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The map label for this gene is fabD [H]

Identifier: 157962316

GI number: 157962316

Start: 3040506

End: 3041432

Strand: Reverse

Name: fabD [H]

Synonym: Spea_2495

Alternate gene names: 157962316

Gene position: 3041432-3040506 (Counterclockwise)

Preceding gene: 157962317

Following gene: 157962315

Centisome position: 58.78

GC content: 46.17

Gene sequence:

>927_bases
ATGGAAAATACTGCTTTTGTATTCCCAGGACAAGGTTCTCAAGCATTAGGAATGCTAGCCGAGTTGGCCGAAGCGCATAG
CGTAGTCGGTGAGACTTTCGCTCAAGCAACCAGTGTTCTTGGGTACGATTTATGGGCTTTGATTCAGCAAGGCCCTGTTG
AAACTCTAAATGAAACAGATAAGACACAGCCTGCACTATTAGCTGCGAGTGTGGCTATTTACCGTGCTTATTTGGCATCG
GGTAAAGGTTTGCCAAAGCTTATGGCAGGTCATAGCTTAGGTGAATACTCAGCATTGGTTTGCGCAGGCGTTATTGATTT
TGAAGCGGCAATTAAATTGGTTGAGCTACGTGGTCAACTAATGCAACAAGCCGTGCCTGCAGGCACTGGTGCTATGTTTG
CAATTATCGGTTTAGATAATGATGCTATCGCAAAAGCTTGTGAAGAAGCGTCAGAAGGCGCAGTCGTTAGCCCTGTTAAC
TACAACAGCCCTGGCCAAGTGGTTATTGCAGGTGAAAAAGCGGCTGTTGAACGCGCTGCAGCACTTTGTAAAGCCAACGG
TGCTAAAATGGCGGTTTCACTGCCTGTAAGCGTGCCGTCGCATTGCCAATTGATGAAGCCTGCTGCCGATAAACTTGCCG
TAGCACTTGAAGCGATAGAATTTAATGAGCCAGCGGTTACCGTTATCAACAATGTTGATGTGGCTAGCCCTAATTCTGCT
GCTGATATTAAAGATGCTTTGGTTCGTCAACTATATTGTCCGGTTCGTTGGTCTGAGACTGTCGAGTTGATGGCTATCGA
TGGGATCACGAATCTGTTTGAAATGGGACCTGGTAAAGTTTTAACGGGTCTAACAAAACGTATTAATCGCTCGCTTTCGG
CACAAGCTGTAAACGATGTGGCTTCATTAACGGCGTTGACCGAATAA

Upstream 100 bases:

>100_bases
GAAGTGCTTTAGTTCGTTTTTAATTATTGTCTTAGATATAGTCTTAGATAAGGTCTTATTGATAACAGTCAAAAGACGTC
GATTTAAAGGGTAGGATAAT

Downstream 100 bases:

>100_bases
GGAAATCTGATGAGTATAAGTTTTGATTTGACTGGTAAAGTAGCCTTAGTTACAGGCGCTAGCCGTGGTATTGGACGCGC
AGTTGCTGAAACATTAGTTT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MENTAFVFPGQGSQALGMLAELAEAHSVVGETFAQATSVLGYDLWALIQQGPVETLNETDKTQPALLAASVAIYRAYLAS
GKGLPKLMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQLMQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGAVVSPVN
YNSPGQVVIAGEKAAVERAAALCKANGAKMAVSLPVSVPSHCQLMKPAADKLAVALEAIEFNEPAVTVINNVDVASPNSA
ADIKDALVRQLYCPVRWSETVELMAIDGITNLFEMGPGKVLTGLTKRINRSLSAQAVNDVASLTALTE

Sequences:

>Translated_308_residues
MENTAFVFPGQGSQALGMLAELAEAHSVVGETFAQATSVLGYDLWALIQQGPVETLNETDKTQPALLAASVAIYRAYLAS
GKGLPKLMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQLMQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGAVVSPVN
YNSPGQVVIAGEKAAVERAAALCKANGAKMAVSLPVSVPSHCQLMKPAADKLAVALEAIEFNEPAVTVINNVDVASPNSA
ADIKDALVRQLYCPVRWSETVELMAIDGITNLFEMGPGKVLTGLTKRINRSLSAQAVNDVASLTALTE
>Mature_308_residues
MENTAFVFPGQGSQALGMLAELAEAHSVVGETFAQATSVLGYDLWALIQQGPVETLNETDKTQPALLAASVAIYRAYLAS
GKGLPKLMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQLMQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGAVVSPVN
YNSPGQVVIAGEKAAVERAAALCKANGAKMAVSLPVSVPSHCQLMKPAADKLAVALEAIEFNEPAVTVINNVDVASPNSA
ADIKDALVRQLYCPVRWSETVELMAIDGITNLFEMGPGKVLTGLTKRINRSLSAQAVNDVASLTALTE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=312, Percent_Identity=34.2948717948718, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI27477045, Length=114, Percent_Identity=41.2280701754386, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=66.2337662337662, Blast_Score=395, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI71984332, Length=299, Percent_Identity=29.0969899665552, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=291, Percent_Identity=27.8350515463918, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24665753, Length=319, Percent_Identity=31.974921630094, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32011; Mature: 32011

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTAFVFPGQGSQALGMLAELAEAHSVVGETFAQATSVLGYDLWALIQQGPVETLNETD
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
KTQPALLAASVAIYRAYLASGKGLPKLMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGAVVSPVNYNSPGQVVIAGEKAAVERAA
HHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEECCCCCCCCCCEEEECCHHHHHHHH
ALCKANGAKMAVSLPVSVPSHCQLMKPAADKLAVALEAIEFNEPAVTVINNVDVASPNSA
HHHHCCCCEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
ADIKDALVRQLYCPVRWSETVELMAIDGITNLFEMGPGKVLTGLTKRINRSLSAQAVNDV
HHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLTALTE
HHHHHCCC
>Mature Secondary Structure
MENTAFVFPGQGSQALGMLAELAEAHSVVGETFAQATSVLGYDLWALIQQGPVETLNETD
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
KTQPALLAASVAIYRAYLASGKGLPKLMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGAVVSPVNYNSPGQVVIAGEKAAVERAA
HHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEECCCCCCCCCCEEEECCHHHHHHHH
ALCKANGAKMAVSLPVSVPSHCQLMKPAADKLAVALEAIEFNEPAVTVINNVDVASPNSA
HHHHCCCCEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
ADIKDALVRQLYCPVRWSETVELMAIDGITNLFEMGPGKVLTGLTKRINRSLSAQAVNDV
HHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLTALTE
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]