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The map label for this gene is speA [H]

Identifier: 157962301

GI number: 157962301

Start: 3025010

End: 3026923

Strand: Reverse

Name: speA [H]

Synonym: Spea_2480

Alternate gene names: 157962301

Gene position: 3026923-3025010 (Counterclockwise)

Preceding gene: 157962306

Following gene: 157962300

Centisome position: 58.5

GC content: 44.98

Gene sequence:

>1914_bases
ATGAGCAATTGGTCTATTGATGATGCACGCGCAAGTTATAACGTAAATCACTGGAGCCAAGGACTATACGGCATTAGCGA
TGATGGAGAGGTGACTGTTTCACCAGATCCAAGCCGCCCAGATTGTAAGATTGGTTTGAATGAAATGGCAAAAGATATGG
TTAAGTCAGGTGTGGCTTTACCCGTTTTGGTGCGTTTCCCACAAATTTTACATCATAGAGTAAATAGTGTTTGTCAGGCA
TTTAATCAGGCAATTAATAAGTATCAATATGAAAATGATTACTTACTGGTTTACCCGATTAAAGTGAACCAACAGCAAAC
TGTTGTTGAAGAGATCCTTGCCAGCCAGGTAGCAAAAGAAGTACCACAGCTAGGTTTAGAAGCGGGCAGTAAGCCGGAGC
TAATGGCAGTACTGGCGATGGCTCAAAAAGCCAGTTCGGTGATCATTTGTAACGGCTATAAAGATAAAGAATATATCCGT
CTTGCCTTAATCGGTGAAAAGCTAGGTCACAAGGTGTATATCGTCCTTGAGAAGATGTCAGAGCTTAAAGTCGTGCTTGA
GCAAGCTAAAGAGCTCGGCGTTACGCCGCGTCTTGGTTTACGTGTCCGTTTGGCATTCCAAGGTAAAGGTAAGTGGCAGG
CTAGTGGTGGCGAGAAGTCAAAGTTTGGATTGAGTGCTGCTCAGGTGTTGCAAGTGATCAACTCACTTAAGCAGGAAAAC
ATGCTTGAGTCATTAGAGTTGTTGCACTTCCACTTAGGTTCGCAAATCGCCAATATTCGCGATATTCGACAAGGTGTTAG
CGAGGCTGGCCGTTTCTATTGTGAGTTGATGAAACTTGGCGCCAGTGTTAAGTGTTTCGACGTGGGTGGCGGCTTAGCTG
TTGATTACGATGGTACGCGTAGCCAAAGCAGCCATTCAATGAACTATGGCTTAACCGAGTATGCTAACAATATCGTGAGT
GTTCTCACTGATATGTGTAAAGAGTATGAGCAGCCGATGCCGAGAATTATCTCAGAATCGGGCCGTTACTTGACTGCACA
TCATGCGGTATTACTAACTGACGTGATTGGTACTGAAGCGTATAAGCCTGAAGATATTCAGCCTCCTGCAGAAGACGCAC
CTCAGTTACTGCACAACATGTGGCAGTCTTGGATCGAAGTCAGTGGTAAAGCCGATCAGCGCGCCTTGATTGAGATTTAT
CATGATTGCCAGAGCGACTTAACTGAAGTGCACTCGCTGTTTGCCGTTGGTCAGTTAGGTTTAGCTGAGCGTGCATGGGC
GGAGCAGGTAAACTTACGCGTATGTTACGAACTACAAGGTAGCATGAGCGCTAAGTACCGTTTCCACAGACCGGTTATTG
ATGAGCTAAACGAAAAACTAGCAGACAAGTTCTTCGTTAACTTCTCATTGTTCCAGTCACTTCCTGACGCTTGGGGTATC
GATCAGGTATTCCCTGTAATGCCACTATCAGGACTTGATAAGGCGCCAGAGAGCAGGGCGGTAATGTTAGACATCACCTG
TGACTCAGACGGTACAGTGGATCAGTACGTAGAAGGTCAAGGTATTGAAACAACGTTACCAGTACCTGCTTGGACACAAG
AGAGCCCATATTTAATCGGTTTCTTCTTAGTCGGTGCATATCAAGAGATTTTAGGTGATATGCATAACTTGTTTGGTGAC
ACTAACTCAGCCGTTGTTCGTTTGGACGACGATGCGCGCACTAACGTTGAGTCGGTATTGGCCGGTGATACGGTTGCCGA
CGTGCTTAGATATGTGAACTTGGATGCGGTTTCATTTATGAGAACCTATGAAGAGTTAGTGAACAAGCATATTGCTGAAG
ACGAGCGTGCTAATATTCTTGAAGAACTACAGTTAGGTCTTAAAGGTTACACTTACCTAGAAGACTTCTCGTAA

Upstream 100 bases:

>100_bases
AGATGAATCGGGATGTTACTGATTCAAATAATCGCAAGTTGATTGAAACGACAAAGAATCGATCAACTTATTTGAGTTAA
ATAGACAGGTTAGGACAAAT

Downstream 100 bases:

>100_bases
TTGTATGGATAGTCGAGTGGGGTTAGCAGCCGAAGTATTTTTATAAAGGCTAGCAACTGCTCTCGAGCTACATAACCAGC
TTTAAGCTCGCTTGAAGCTG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPDCKIGLNEMAKDMVKSGVALPVLVRFPQILHHRVNSVCQA
FNQAINKYQYENDYLLVYPIKVNQQQTVVEEILASQVAKEVPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIR
LALIGEKLGHKVYIVLEKMSELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVINSLKQEN
MLESLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGASVKCFDVGGGLAVDYDGTRSQSSHSMNYGLTEYANNIVS
VLTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEAYKPEDIQPPAEDAPQLLHNMWQSWIEVSGKADQRALIEIY
HDCQSDLTEVHSLFAVGQLGLAERAWAEQVNLRVCYELQGSMSAKYRFHRPVIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVMPLSGLDKAPESRAVMLDITCDSDGTVDQYVEGQGIETTLPVPAWTQESPYLIGFFLVGAYQEILGDMHNLFGD
TNSAVVRLDDDARTNVESVLAGDTVADVLRYVNLDAVSFMRTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS

Sequences:

>Translated_637_residues
MSNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPDCKIGLNEMAKDMVKSGVALPVLVRFPQILHHRVNSVCQA
FNQAINKYQYENDYLLVYPIKVNQQQTVVEEILASQVAKEVPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIR
LALIGEKLGHKVYIVLEKMSELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVINSLKQEN
MLESLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGASVKCFDVGGGLAVDYDGTRSQSSHSMNYGLTEYANNIVS
VLTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEAYKPEDIQPPAEDAPQLLHNMWQSWIEVSGKADQRALIEIY
HDCQSDLTEVHSLFAVGQLGLAERAWAEQVNLRVCYELQGSMSAKYRFHRPVIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVMPLSGLDKAPESRAVMLDITCDSDGTVDQYVEGQGIETTLPVPAWTQESPYLIGFFLVGAYQEILGDMHNLFGD
TNSAVVRLDDDARTNVESVLAGDTVADVLRYVNLDAVSFMRTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS
>Mature_636_residues
SNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPDCKIGLNEMAKDMVKSGVALPVLVRFPQILHHRVNSVCQAF
NQAINKYQYENDYLLVYPIKVNQQQTVVEEILASQVAKEVPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIRL
ALIGEKLGHKVYIVLEKMSELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVINSLKQENM
LESLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGASVKCFDVGGGLAVDYDGTRSQSSHSMNYGLTEYANNIVSV
LTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEAYKPEDIQPPAEDAPQLLHNMWQSWIEVSGKADQRALIEIYH
DCQSDLTEVHSLFAVGQLGLAERAWAEQVNLRVCYELQGSMSAKYRFHRPVIDELNEKLADKFFVNFSLFQSLPDAWGID
QVFPVMPLSGLDKAPESRAVMLDITCDSDGTVDQYVEGQGIETTLPVPAWTQESPYLIGFFLVGAYQEILGDMHNLFGDT
NSAVVRLDDDARTNVESVLAGDTVADVLRYVNLDAVSFMRTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=636, Percent_Identity=54.559748427673, Blast_Score=722, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71055; Mature: 70923

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPDCKIGLNEMAKDMVKSGVAL
CCCCCCCCHHCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCH
PVLVRFPQILHHRVNSVCQAFNQAINKYQYENDYLLVYPIKVNQQQTVVEEILASQVAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIRLALIGEKLGHKVYIVLEKMS
HHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHEEEEEEHHHHCCEEEEEHHHHH
ELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVINSLKQEN
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHH
MLESLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGASVKCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCC
SQSSHSMNYGLTEYANNIVSVLTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEHHHHHHHHHHCCCC
YKPEDIQPPAEDAPQLLHNMWQSWIEVSGKADQRALIEIYHDCQSDLTEVHSLFAVGQLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LAERAWAEQVNLRVCYELQGSMSAKYRFHRPVIDELNEKLADKFFVNFSLFQSLPDAWGI
HHHHHHHHHCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DQVFPVMPLSGLDKAPESRAVMLDITCDSDGTVDQYVEGQGIETTLPVPAWTQESPYLIG
CHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHCCCCCCEECCCCCCCCCCCCEEH
FFLVGAYQEILGDMHNLFGDTNSAVVRLDDDARTNVESVLAGDTVADVLRYVNLDAVSFM
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHCHHHHHHH
RTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
SNWSIDDARASYNVNHWSQGLYGISDDGEVTVSPDPSRPDCKIGLNEMAKDMVKSGVAL
CCCCCCCHHCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCH
PVLVRFPQILHHRVNSVCQAFNQAINKYQYENDYLLVYPIKVNQQQTVVEEILASQVAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIICNGYKDKEYIRLALIGEKLGHKVYIVLEKMS
HHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHEEEEEEHHHHCCEEEEEHHHHH
ELKVVLEQAKELGVTPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLQVINSLKQEN
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHH
MLESLELLHFHLGSQIANIRDIRQGVSEAGRFYCELMKLGASVKCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCC
SQSSHSMNYGLTEYANNIVSVLTDMCKEYEQPMPRIISESGRYLTAHHAVLLTDVIGTEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEHHHHHHHHHHCCCC
YKPEDIQPPAEDAPQLLHNMWQSWIEVSGKADQRALIEIYHDCQSDLTEVHSLFAVGQLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LAERAWAEQVNLRVCYELQGSMSAKYRFHRPVIDELNEKLADKFFVNFSLFQSLPDAWGI
HHHHHHHHHCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DQVFPVMPLSGLDKAPESRAVMLDITCDSDGTVDQYVEGQGIETTLPVPAWTQESPYLIG
CHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHCCCCCCEECCCCCCCCCCCCEEH
FFLVGAYQEILGDMHNLFGDTNSAVVRLDDDARTNVESVLAGDTVADVLRYVNLDAVSFM
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHCHHHHHHH
RTYEELVNKHIAEDERANILEELQLGLKGYTYLEDFS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA