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The map label for this gene is trxB [H]

Identifier: 157962079

GI number: 157962079

Start: 2737834

End: 2738784

Strand: Direct

Name: trxB [H]

Synonym: Spea_2258

Alternate gene names: 157962079

Gene position: 2737834-2738784 (Clockwise)

Preceding gene: 157962075

Following gene: 157962085

Centisome position: 52.91

GC content: 46.37

Gene sequence:

>951_bases
ATGACCCAAGCTAGACATTGTGACTTACTTATTCTGGGTTCTGGCCCAGCAGGCTATACGGCCGCAGTTTATGCCGCTCG
CGCAAATTTAAAGCCTGTATTGATCACTGGTATTCAACAAGGTGGACAATTAACCACCACGACTGAAGTAGAAAACTGGC
CAGGAGATGCTGAAGACTTAACAGGTCCAGCATTGATGGAGCGTATGCAGAAGCACGCTGAAAAGTTTGAAACTGAGATT
ATTTTCGATCACATCAACGAAGTGAACCTAAATGTTCGCCCTTTCCAACTGAAAGGCGACAACGGTGAATTCACTTGTGA
CTCACTCATCATCTCGACTGGTGCATCAGCCATCTACCTTGGCCTAGAGTCTGAAGAAGCGTTTAAAGGCCGCGGCGTAT
CAGCCTGTGCGACCTGTGACGGTTTCTTCTATCGTAACCAGAAAGTTGCCGTGATCGGTGGCGGTAACACTGCCGTTGAA
GAAGCACTTTACTTAAGCAACATCGCGTCTGAGGTTCATCTTATTCACCGTCGTGATAGCTTCCGCAGTGAGAAGATCTT
AACTAAGCGCCTGATGGACAAAGTAGCCAATGGCAACATCATCCTTCACCTTGATAACACACTCGATGAAGTAGTTGGCG
ATCAAATGGGTGTAACGGGTCTTAAGATGAAGAGCACTAAAGACGGTAGCATTAAGGATCTTGAAGTTGCTGGCGTATTC
GTTGCTATTGGCCATAAGCCAAACACATCTATGTTTGAAGGCCAGTTAGAAATGAACAATGGCTATATCAAAGTGCAAAG
TGGCCTTGATGGTAACGCGACTCAAACTAGCATCGAAGGTGTGTTTGCAGCAGGTGATGTGATGGATCAACATTACCGCC
AAGCAATTACATCAGCAGGTACTGGCTGTATGGCGGCATTAGACGCAGAACGTTACCTAGACGCAAAATAG

Upstream 100 bases:

>100_bases
TACCCCTTACCTGAAATTCCATACAATCGCTGCAATTCGTAAAACAAGAGGGATACTATTCCCCTTGCAGTACCGTATTC
GTTAAAGAACGGAGAGACTA

Downstream 100 bases:

>100_bases
GAATAACTAAATAAGAGCGCTTAAATAAGCACTCTATTGTTAAACTAAAAAGCCAACACTCAGTGTTGGCTTTTTATTTT
CTACTATTTTATTTTTAGTT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTQARHCDLLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDLTGPALMERMQKHAEKFETEI
IFDHINEVNLNVRPFQLKGDNGEFTCDSLIISTGASAIYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIASEVHLIHRRDSFRSEKILTKRLMDKVANGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDGSIKDLEVAGVF
VAIGHKPNTSMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERYLDAK

Sequences:

>Translated_316_residues
MTQARHCDLLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDLTGPALMERMQKHAEKFETEI
IFDHINEVNLNVRPFQLKGDNGEFTCDSLIISTGASAIYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIASEVHLIHRRDSFRSEKILTKRLMDKVANGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDGSIKDLEVAGVF
VAIGHKPNTSMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERYLDAK
>Mature_315_residues
TQARHCDLLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDLTGPALMERMQKHAEKFETEII
FDHINEVNLNVRPFQLKGDNGEFTCDSLIISTGASAIYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEE
ALYLSNIASEVHLIHRRDSFRSEKILTKRLMDKVANGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDGSIKDLEVAGVFV
AIGHKPNTSMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERYLDAK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=80.9523809523809, Blast_Score=533, Evalue=1e-153,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6321898, Length=328, Percent_Identity=46.6463414634146, Blast_Score=282, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=46.25, Blast_Score=271, Evalue=1e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34085; Mature: 33954

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQARHCDLLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDL
CCCCCCCCEEEECCCCCCCCEEEEEHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHC
TGPALMERMQKHAEKFETEIIFDHINEVNLNVRPFQLKGDNGEFTCDSLIISTGASAIYL
CCHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCEEEHEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDS
EECCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHEEHHCCC
FRSEKILTKRLMDKVANGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDGSIKDLEVAGVF
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEEEE
VAIGHKPNTSMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHCEEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDAK
CCCEEEECHHHHCCCC
>Mature Secondary Structure 
TQARHCDLLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDL
CCCCCCCEEEECCCCCCCCEEEEEHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHC
TGPALMERMQKHAEKFETEIIFDHINEVNLNVRPFQLKGDNGEFTCDSLIISTGASAIYL
CCHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCEEEHEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDS
EECCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHEEHHCCC
FRSEKILTKRLMDKVANGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDGSIKDLEVAGVF
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEEEE
VAIGHKPNTSMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHCEEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDAK
CCCEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]