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The map label for this gene is slyD [H]

Identifier: 157961728

GI number: 157961728

Start: 2316083

End: 2316565

Strand: Direct

Name: slyD [H]

Synonym: Spea_1905

Alternate gene names: 157961728

Gene position: 2316083-2316565 (Clockwise)

Preceding gene: 157961727

Following gene: 157961729

Centisome position: 44.76

GC content: 46.38

Gene sequence:

>483_bases
ATGAGCATTAAAGATGATTCAGTTGTGCAGTTTAACTACACATTACGTGATGAGCAGGGCGAAGTTTTAGAAACCAATGA
CGGTTTAGAGCCAATCGCCTACCTTCATGGCCATGACAACATGATGCATGGTGTTGAAGATGCACTTACCGGTAAAGACG
TTGGTGCTAAATTCTCTGTAACTTTGCCAGCGAGCCAAACTTATGGTGAGCGTAATGAAGACGCCGAACAACGCGTTTCG
GTAAAGCATCTTCAAGGTGCTAGTGTATGGAAACCTGGTATGCGCGCATTGATCAACACAGATCAAGGTCAGCGCCAAGT
CACTATCGTAAAGATGGGGAAGTTTATGGCAACTGTGGATGTTAACCATCCACTGGCAGGCCGTGAATTAACCTTCGATC
TTGAAGTGATGGACGTCCGTGATGCGACTAGTGAAGAGATTGCCCATGGTCATGCCCACGGTAAAGGTGGACACCAACAC
TAA

Upstream 100 bases:

>100_bases
GAGTGATATAATTTTGACTCATTAGATAACACTAGAGGGTTCAGGCGAGTTTTGTTAAGCTGCGGCCACTAAATTAGAGC
GAACAGTGTTAAGGAATACC

Downstream 100 bases:

>100_bases
GCTGGCTTTGTCAGTTGACTAAAGCCCAACAGTGTTGGGCTTTTTTATTGCATCTTAGAGATATTAACTCGTTATGATTG
TTCAATTTTCTGCTGGAAAA

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSIKDDSVVQFNYTLRDEQGEVLETNDGLEPIAYLHGHDNMMHGVEDALTGKDVGAKFSVTLPASQTYGERNEDAEQRVS
VKHLQGASVWKPGMRALINTDQGQRQVTIVKMGKFMATVDVNHPLAGRELTFDLEVMDVRDATSEEIAHGHAHGKGGHQH

Sequences:

>Translated_160_residues
MSIKDDSVVQFNYTLRDEQGEVLETNDGLEPIAYLHGHDNMMHGVEDALTGKDVGAKFSVTLPASQTYGERNEDAEQRVS
VKHLQGASVWKPGMRALINTDQGQRQVTIVKMGKFMATVDVNHPLAGRELTFDLEVMDVRDATSEEIAHGHAHGKGGHQH
>Mature_159_residues
SIKDDSVVQFNYTLRDEQGEVLETNDGLEPIAYLHGHDNMMHGVEDALTGKDVGAKFSVTLPASQTYGERNEDAEQRVSV
KHLQGASVWKPGMRALINTDQGQRQVTIVKMGKFMATVDVNHPLAGRELTFDLEVMDVRDATSEEIAHGHAHGKGGHQH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=149, Percent_Identity=40.2684563758389, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17647; Mature: 17516

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKDDSVVQFNYTLRDEQGEVLETNDGLEPIAYLHGHDNMMHGVEDALTGKDVGAKFSV
CCCCCCCEEEEEEEEECCCCCEEECCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCEEEE
TLPASQTYGERNEDAEQRVSVKHLQGASVWKPGMRALINTDQGQRQVTIVKMGKFMATVD
EECCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHEEECCCCCCEEEEEEEECCEEEEEE
VNHPLAGRELTFDLEVMDVRDATSEEIAHGHAHGKGGHQH
CCCCCCCCEEEEEEEEEECCCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SIKDDSVVQFNYTLRDEQGEVLETNDGLEPIAYLHGHDNMMHGVEDALTGKDVGAKFSV
CCCCCCEEEEEEEEECCCCCEEECCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCEEEE
TLPASQTYGERNEDAEQRVSVKHLQGASVWKPGMRALINTDQGQRQVTIVKMGKFMATVD
EECCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHEEECCCCCCEEEEEEEECCEEEEEE
VNHPLAGRELTFDLEVMDVRDATSEEIAHGHAHGKGGHQH
CCCCCCCCEEEEEEEEEECCCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]