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The map label for this gene is ptxB [H]

Identifier: 157961571

GI number: 157961571

Start: 2124429

End: 2125283

Strand: Direct

Name: ptxB [H]

Synonym: Spea_1747

Alternate gene names: 157961571

Gene position: 2124429-2125283 (Clockwise)

Preceding gene: 157961568

Following gene: 157961572

Centisome position: 41.06

GC content: 45.26

Gene sequence:

>855_bases
ATGTCGTTTGTTAGGCTACTTACTGGGTTAGCACTGCTTTTACTCGCACCGAGTGTAATGGCCACAACGTTTACGTTTAC
TGCAATTCCCGATGAAGATGAGAGTCAATTAAGAACGCGATTCGATAAAGTTGCTGTCTACCTAGAGGAAAAGCTTGGGG
TTGAGGTTAAGTATGTTCCGGTTAAATCATACTCTGCAGCCGTTACTGCTTTTCGTAATAACCAAGTCCAATTAGCCTGG
TTTGGCGGTCTATCTGGCGTACAGGCACGTCGTTTGGTGCCAGGTTCAGAGGCCATAGCACAAGGCTATGAAGATCAGTT
TTTCAAGAGCTACTTTATTGCCCACTCCTCAGCGGAGATCATCCCAAGTGATAGTTTTCCTAATTTAAACGGTTATACCT
TTACTTATGGCTCTAAAAATTCAACTTCCGGTCGCCTGATGCCGCAGTTCTTTATCGAGCGAAATCTAGGTAAGAACAGT
AAGGATATCTTTAAACGCATAGGTTATTCCGGTGACCATAGCCGTACCATTGCTCAGGTACAGGCGGGGGTCTATCAAGT
CGGTGCGGTTAATTACAAGGTATGGGAAACTGCCCTATCAAACGGCAAAGTGGATCTCAATAAGGTCAGTGTTATTTGGG
AAACCCCAGCGTACCCCGATTATCAGTGGACCATACGTGGTGATATTGACGGCAAATTTGGTGCAGGTTTTAGCGAAAAA
GTGACAGCAGCACTCATCGGTATGAAAGATCCTGAGCTGTTAGAGAGCTTTCCTCGCCAGTCATTTGTCCCCGCTGATAA
CCGAGACTATGAAGCGATTGAAGACGTTGCTAAAGCAATTGGCCTAATTGACTAG

Upstream 100 bases:

>100_bases
GATTTATTCAGTTAGACGTTATTTCGTACCGTTATCTCTGGGTTTATTGCTGCTTTTTCGTTAAGATTCCGTAAATTTTT
TTAAGCTGAAGGATTAAGGT

Downstream 100 bases:

>100_bases
GCTACCTTGGGTAAATTTAGCTTGGGCAAGCCTAAGTTGGCTAAGCAGATGTCGATTCACTCCAAATTGGCTCATTCAGA
GTTGAATCGGCCTATGTTGA

Product: phosphonate ABC transporter periplasmic phosphonate-binding protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSFVRLLTGLALLLLAPSVMATTFTFTAIPDEDESQLRTRFDKVAVYLEEKLGVEVKYVPVKSYSAAVTAFRNNQVQLAW
FGGLSGVQARRLVPGSEAIAQGYEDQFFKSYFIAHSSAEIIPSDSFPNLNGYTFTYGSKNSTSGRLMPQFFIERNLGKNS
KDIFKRIGYSGDHSRTIAQVQAGVYQVGAVNYKVWETALSNGKVDLNKVSVIWETPAYPDYQWTIRGDIDGKFGAGFSEK
VTAALIGMKDPELLESFPRQSFVPADNRDYEAIEDVAKAIGLID

Sequences:

>Translated_284_residues
MSFVRLLTGLALLLLAPSVMATTFTFTAIPDEDESQLRTRFDKVAVYLEEKLGVEVKYVPVKSYSAAVTAFRNNQVQLAW
FGGLSGVQARRLVPGSEAIAQGYEDQFFKSYFIAHSSAEIIPSDSFPNLNGYTFTYGSKNSTSGRLMPQFFIERNLGKNS
KDIFKRIGYSGDHSRTIAQVQAGVYQVGAVNYKVWETALSNGKVDLNKVSVIWETPAYPDYQWTIRGDIDGKFGAGFSEK
VTAALIGMKDPELLESFPRQSFVPADNRDYEAIEDVAKAIGLID
>Mature_283_residues
SFVRLLTGLALLLLAPSVMATTFTFTAIPDEDESQLRTRFDKVAVYLEEKLGVEVKYVPVKSYSAAVTAFRNNQVQLAWF
GGLSGVQARRLVPGSEAIAQGYEDQFFKSYFIAHSSAEIIPSDSFPNLNGYTFTYGSKNSTSGRLMPQFFIERNLGKNSK
DIFKRIGYSGDHSRTIAQVQAGVYQVGAVNYKVWETALSNGKVDLNKVSVIWETPAYPDYQWTIRGDIDGKFGAGFSEKV
TAALIGMKDPELLESFPRQSFVPADNRDYEAIEDVAKAIGLID

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=201, Percent_Identity=25.3731343283582, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 31482; Mature: 31351

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVRLLTGLALLLLAPSVMATTFTFTAIPDEDESQLRTRFDKVAVYLEEKLGVEVKYVP
CHHHHHHHHHHHHHHCCHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEE
VKSYSAAVTAFRNNQVQLAWFGGLSGVQARRLVPGSEAIAQGYEDQFFKSYFIAHSSAEI
CCCCCCEEEEEECCEEEEEEECCCCCCCHHCCCCCHHHHHCCHHHHHHHHHHHHCCCCCC
IPSDSFPNLNGYTFTYGSKNSTSGRLMPQFFIERNLGKNSKDIFKRIGYSGDHSRTIAQV
CCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
QAGVYQVGAVNYKVWETALSNGKVDLNKVSVIWETPAYPDYQWTIRGDIDGKFGAGFSEK
HHCEEEECCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHH
VTAALIGMKDPELLESFPRQSFVPADNRDYEAIEDVAKAIGLID
HHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFVRLLTGLALLLLAPSVMATTFTFTAIPDEDESQLRTRFDKVAVYLEEKLGVEVKYVP
HHHHHHHHHHHHHHCCHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEE
VKSYSAAVTAFRNNQVQLAWFGGLSGVQARRLVPGSEAIAQGYEDQFFKSYFIAHSSAEI
CCCCCCEEEEEECCEEEEEEECCCCCCCHHCCCCCHHHHHCCHHHHHHHHHHHHCCCCCC
IPSDSFPNLNGYTFTYGSKNSTSGRLMPQFFIERNLGKNSKDIFKRIGYSGDHSRTIAQV
CCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
QAGVYQVGAVNYKVWETALSNGKVDLNKVSVIWETPAYPDYQWTIRGDIDGKFGAGFSEK
HHCEEEECCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHH
VTAALIGMKDPELLESFPRQSFVPADNRDYEAIEDVAKAIGLID
HHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]