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The map label for this gene is aceB [H]

Identifier: 157961118

GI number: 157961118

Start: 1573642

End: 1575306

Strand: Direct

Name: aceB [H]

Synonym: Spea_1290

Alternate gene names: 157961118

Gene position: 1573642-1575306 (Clockwise)

Preceding gene: 157961117

Following gene: 157961119

Centisome position: 30.41

GC content: 46.97

Gene sequence:

>1665_bases
ATGAGCAAAGTTTTGGGAGATAAAATGATGACAGAGCAATTAACAGCGCTAGATACTTGCGACGCACTGGTATCGAGTCA
AGAGTTACAGATAAAAGGGCAAGCTGTTGCAGGGCAGGAGCAGGTATTAACTGAAGGCACACTGTGCTTGTTAAAGGCAT
TGTGTAAGCAGTTTGCGCCACAGGTGCCAGATTTACTTGCTAATAGGCAGGCAAAGCAAAAGCGTATTGATTTAGGTGAG
TTGCCCGATTTTTTGGAGGAGACCAAGGAGATCCGTCAAGGGAATTGGCAGATCCGAGGTATTCCTGAAGACTTACAAGA
TAGGCGCGTAGAGATCACCGGGCCTGTTGAGCGCAAGATGGTGATCAATGCGCTTAATGCTAATGCCAAAGTGTTTATGG
CCGATTTTGAGGATTCACTGGCGCCAAGCTGGCACAAGGTGGTGCAAGGTCAAATCAACCTGCGGGATGCGGTGAACGGT
GATATTGGCTATACGGCGCCAGAAACAGGCAAGCATTATTCATTAAATGACAATCCTGCGGTGCTTATTTGCCGAGTCCG
TGGTCTACATATGCAAGAGCAGCATGTGCAGTTTGGCGGCGTCGCCATTCCTGCTGGCTTGTTCGATTTTTGTGTCTATT
TCTACAATAACTACTGTAAGTTATTGAGTAAGGGCAGCGGGCCGTATTTTTATATTCCTAAGCTAGAAAGCCATCTAGAG
GCCAAGTGGTGGGCAAGAGTGTTTGCTTTTGTTGAGGCGCGTTTCTGTTTACAGCCTGGCACCATAAAATGTACCTGCCT
AATTGAAACCCTACCCGCCGTCTTTGAGATGGATGAGATCTTGTATGAACTGCGCTCTAACATCGTTGCGCTTAATTGCG
GTCGTTGGGACTATATATTTAGCTATATTAAAACCCTAAATAACCATAGCGACAGAGTGCTGCCCGACAGGCAGTCGGTC
ACCATGGATAAGCCATTTTTAAGTGCTTACTCTCGCTTATTGATCAAGACCTGCCACAAGCGTGGTGCGTTAGCTATGGG
CGGCATGGCAGCCTTTATTCCAGCAAAAGATACTGAGCTCAATCAACAAGTGCTAGCTAAGGTTAAACAGGATAAGCAAC
TCGAAGCGCGAAATGGCCATGATGGCACTTGGGTAGCACATCCTGGGCTGGCCGATACTGCGATGGCAATTTTTAATGAA
TACATAGGTGAAGACCATATTAATCAACTACACATTACCCGTGATGTTGACGCCCCTATTCATGCTAGAGAGTTACTCGA
ACCTGCAAAGGGGCAATGTACAGAAGCTGGCATGCGCCTCAATATTAGAATTGCACTGCAATACATAGAGTCGTGGATTA
ACGGCAATGGCTGCGTGCCTATCTATGGCTTAATGGAGGATGCGGCTACGGCTGAAATATCTCGCACTTCAATTTGGCAG
TGGATTAAGCATCGTCAGCAGCTTACCTCTGGGGCTGTGGTCACTAAGGCACTATTTAAGGATATGTTGGTAGAAGAGCT
CGCCCACGTTAAAGATGAGGTAGGGGCCGATCGTTTTACTCACGGCAGTTTTACTCAGGCCGCAGTCTTGCTAGAGCAGA
TCACTACAGCAGACGAGTTGGTCGATTTTTTAACTGAGCCGGGATATCAACTGTTGGTGGAGTAA

Upstream 100 bases:

>100_bases
AGGTTCAGGTTAAGCACGACTTTATGAAAGGCATGCTAGGGAACTGGATTAATTGAGCGCTGACGGCCTAAAGCAACCAA
TGCTAGGTGTCATCAAGGAT

Downstream 100 bases:

>100_bases
TACCAATTAGATATTGAGTATGCTTTTTATAAAATCTGCCTTGTTATAAAACCTGCCTTGGTAAAAGTTTGGCTACATCT
TGTAGCTTGTGTCCCCCGCA

Product: malate synthase

Products: NA

Alternate protein names: MSA [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSKVLGDKMMTEQLTALDTCDALVSSQELQIKGQAVAGQEQVLTEGTLCLLKALCKQFAPQVPDLLANRQAKQKRIDLGE
LPDFLEETKEIRQGNWQIRGIPEDLQDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWHKVVQGQINLRDAVNG
DIGYTAPETGKHYSLNDNPAVLICRVRGLHMQEQHVQFGGVAIPAGLFDFCVYFYNNYCKLLSKGSGPYFYIPKLESHLE
AKWWARVFAFVEARFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLNNHSDRVLPDRQSV
TMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDTELNQQVLAKVKQDKQLEARNGHDGTWVAHPGLADTAMAIFNE
YIGEDHINQLHITRDVDAPIHARELLEPAKGQCTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQ
WIKHRQQLTSGAVVTKALFKDMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTADELVDFLTEPGYQLLVE

Sequences:

>Translated_554_residues
MSKVLGDKMMTEQLTALDTCDALVSSQELQIKGQAVAGQEQVLTEGTLCLLKALCKQFAPQVPDLLANRQAKQKRIDLGE
LPDFLEETKEIRQGNWQIRGIPEDLQDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWHKVVQGQINLRDAVNG
DIGYTAPETGKHYSLNDNPAVLICRVRGLHMQEQHVQFGGVAIPAGLFDFCVYFYNNYCKLLSKGSGPYFYIPKLESHLE
AKWWARVFAFVEARFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLNNHSDRVLPDRQSV
TMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDTELNQQVLAKVKQDKQLEARNGHDGTWVAHPGLADTAMAIFNE
YIGEDHINQLHITRDVDAPIHARELLEPAKGQCTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQ
WIKHRQQLTSGAVVTKALFKDMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTADELVDFLTEPGYQLLVE
>Mature_553_residues
SKVLGDKMMTEQLTALDTCDALVSSQELQIKGQAVAGQEQVLTEGTLCLLKALCKQFAPQVPDLLANRQAKQKRIDLGEL
PDFLEETKEIRQGNWQIRGIPEDLQDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWHKVVQGQINLRDAVNGD
IGYTAPETGKHYSLNDNPAVLICRVRGLHMQEQHVQFGGVAIPAGLFDFCVYFYNNYCKLLSKGSGPYFYIPKLESHLEA
KWWARVFAFVEARFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLNNHSDRVLPDRQSVT
MDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDTELNQQVLAKVKQDKQLEARNGHDGTWVAHPGLADTAMAIFNEY
IGEDHINQLHITRDVDAPIHARELLEPAKGQCTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQW
IKHRQQLTSGAVVTKALFKDMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTADELVDFLTEPGYQLLVE

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=543, Percent_Identity=66.2983425414365, Blast_Score=738, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=537, Percent_Identity=47.4860335195531, Blast_Score=473, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI71982926, Length=430, Percent_Identity=49.0697674418605, Blast_Score=389, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6324212, Length=502, Percent_Identity=45.2191235059761, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322222, Length=522, Percent_Identity=43.4865900383142, Blast_Score=408, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 62186; Mature: 62055

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVLGDKMMTEQLTALDTCDALVSSQELQIKGQAVAGQEQVLTEGTLCLLKALCKQFAP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
QVPDLLANRQAKQKRIDLGELPDFLEETKEIRQGNWQIRGIPEDLQDRRVEITGPVERKM
CHHHHHHCCHHHHHCCCHHCCHHHHHHHHHHHCCCCEEECCCHHHHCCEEEEECCHHHHH
VINALNANAKVFMADFEDSLAPSWHKVVQGQINLRDAVNGDIGYTAPETGKHYSLNDNPA
HHHEECCCCEEEEECCCCCCCCCHHHHHCCCCEEHHCCCCCCCCCCCCCCCEEECCCCCE
VLICRVRGLHMQEQHVQFGGVAIPAGLFDFCVYFYNNYCKLLSKGSGPYFYIPKLESHLE
EEEEEECCCCCHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHH
AKWWARVFAFVEARFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIF
HHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHH
SYIKTLNNHSDRVLPDRQSVTMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDTEL
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCHH
NQQVLAKVKQDKQLEARNGHDGTWVAHPGLADTAMAIFNEYIGEDHINQLHITRDVDAPI
HHHHHHHHHHCCCHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCH
HARELLEPAKGQCTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQ
HHHHHHCCCCCCHHHCCCEEEEHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHH
WIKHRQQLTSGAVVTKALFKDMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTADEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
VDFLTEPGYQLLVE
HHHHHCCCCEEECC
>Mature Secondary Structure 
SKVLGDKMMTEQLTALDTCDALVSSQELQIKGQAVAGQEQVLTEGTLCLLKALCKQFAP
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
QVPDLLANRQAKQKRIDLGELPDFLEETKEIRQGNWQIRGIPEDLQDRRVEITGPVERKM
CHHHHHHCCHHHHHCCCHHCCHHHHHHHHHHHCCCCEEECCCHHHHCCEEEEECCHHHHH
VINALNANAKVFMADFEDSLAPSWHKVVQGQINLRDAVNGDIGYTAPETGKHYSLNDNPA
HHHEECCCCEEEEECCCCCCCCCHHHHHCCCCEEHHCCCCCCCCCCCCCCCEEECCCCCE
VLICRVRGLHMQEQHVQFGGVAIPAGLFDFCVYFYNNYCKLLSKGSGPYFYIPKLESHLE
EEEEEECCCCCHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHH
AKWWARVFAFVEARFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIF
HHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHH
SYIKTLNNHSDRVLPDRQSVTMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDTEL
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCHH
NQQVLAKVKQDKQLEARNGHDGTWVAHPGLADTAMAIFNEYIGEDHINQLHITRDVDAPI
HHHHHHHHHHCCCHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCH
HARELLEPAKGQCTEAGMRLNIRIALQYIESWINGNGCVPIYGLMEDAATAEISRTSIWQ
HHHHHHCCCCCCHHHCCCEEEEHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHH
WIKHRQQLTSGAVVTKALFKDMLVEELAHVKDEVGADRFTHGSFTQAAVLLEQITTADEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
VDFLTEPGYQLLVE
HHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3050899; 3060852; 8265357; 9278503 [H]