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The map label for this gene is yegE [H]

Identifier: 157961117

GI number: 157961117

Start: 1570703

End: 1572490

Strand: Direct

Name: yegE [H]

Synonym: Spea_1289

Alternate gene names: 157961117

Gene position: 1570703-1572490 (Clockwise)

Preceding gene: 157961116

Following gene: 157961118

Centisome position: 30.35

GC content: 40.32

Gene sequence:

>1788_bases
ATGAGGACTGTTATATCGATCTTTTTCTTGCTCACATTGTATGCATCTTTTCCGTTGTTTGGCGGGCAAGGTGACTTTGA
TGATGTTTTGGTAAAAATAGAAAAAGCGTTGAGGGCATCTCCTGAACAGGTTGAAAGTTTGATAAATAGATTATTGGTTT
CTTGGGATGAACTATCTAAAGAGCAGCAAATTAAATTAATCGTTTATCAGGCTATAAGGAAAAGCTACAACGGCGAATAT
CGGTCCTCTCAAAATTTTTTGGAGCGTGTAAAAGAGTATAGAGTTAGATCTGATTTGTTAGATGATGTATATCACTATCA
AGCGGTTAATTTAATAGGTTTGAGGCAATATACTGATGCATTCCCATTAATGGAACGTTATCTTAAATCGGTAGAAAATA
TTGGCGATAATAATGTAAAAGCTAAGGCCTATATGAGGATGGCTAACTTAGCATTAAATCTAGAAGCGTATGAGGACCTT
CGGAATTATGGTGAAAAGGCGTTAAGTCTGAGCCAAAGTTCTGATAAAAAAGTTTATTGTTTTTCTCTTATATTGATTGC
GTTTGCAGATCTTAAGGAATATGAACTTAAAGAAGCGGAAAGAGGCTTTAAGAGTAGTAAATTATTTTGTGATCAAAATG
AACTTCCTTTATTCGGTTTCATGTCTGGAAAAGGTTTGGCTGAAATAGCCATGAAAATGGATGATTTTGAAAGCGCCGAA
ATGCAACTTAATGAGGTCCTTGCCGGATACATTAAGTATGGCTATAAAGCGGAAATAATAAGTGTTCATGCTTTGCTTGC
CAAGACGAACCTGCGACTCAAGAAGTATTCTCAAGCTGAAGAGTTTGCTAATAAGGTGATGGGGTTAAGTGATGAGCCCA
GTCATACTGAATATAAAGCTATTGCCAGCAAAGTACTGTCGCAGAGATACTTAGAGTCAAAGCAGTACAAACTTGCCCAT
GATTACCTCGAATCCCATCAACACTATAGTAATTTAATCTTCGATGACACTAAAGCTAAGGCTAATGCCTATCAGATGGC
TAAGTTTAAACACCAAGAACAGGCGCGCGAAATAGCCTTGCTCAATCAGGAGCGGCAATTGGTGGAAACTCAGAAAGAGT
TAGACCGTTCCGACCGGACTAATAATGTCATGATAATGACCATGTTGGCGGGCAGTGTGATTTTCTTGTCGCTATTTTTG
CTATACAGCCACAGACAAAAGGTGCGTTACCGTAGGCTGGCATTAACTGATAGGTTAACCAGTGTTTATAATCGCGGTGC
CGGGCAGGATTTTGCCGAAAATGAGTTCGTACAGGTCAGCATGCGAAAAGCTGATTACGCTGTGATAGTGTTTGATTTAG
ATCTGTTTAAAAACATCAATGATAGTTTTGGTCATGCAACCGGTGACTGGACGTTAAAACATGTGGTGTCGGTGATTAGG
CCGCTTATCCGCGATAGCGATATTTTTACTCGAATGGGAGGTGAAGAGTTTGCATTATTCTTACCTTATTCTAGCGAGCA
GACCGCACTTAAAATAGCCGAGCGCTGTAAACTGGCGGTAGCTGCAATCGATACCAAGTATTCTGGCCATGTGTTTAACA
TTAGTGCTAGCTTTGGCGTATCGTGTAGCACTAGTGAAGATCTCAGTTTAGATCCGTTATTAAAGCGTGCCGATATCGCG
CTCTATGCTTCGAAGCACTCGGGCCGTAATAGAGTGACGTTATACACACCTGAGCTTAAGCTACAGCGCCCGACCGATGA
GACTCAGCGTTCACTGGTGTTTAATTAG

Upstream 100 bases:

>100_bases
GTGATTTCGGGCGATGATAATAAGCTTAAATCTTTCTCTGATGGTAAAAACTATAGCTCCCTTGTATTGGTGTACGCTTC
GGATAAGTGATACTTGAATA

Downstream 100 bases:

>100_bases
GCAAAATTAATCACCTAGTGTACCTAGTGTATTAGCTTGTACTAGTTGTACTAGCGGTCTTAGCTGTATTAGTCGTCTTA
ACCCGGACTCAAGCTGAACT

Product: diguanylate cyclase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MRTVISIFFLLTLYASFPLFGGQGDFDDVLVKIEKALRASPEQVESLINRLLVSWDELSKEQQIKLIVYQAIRKSYNGEY
RSSQNFLERVKEYRVRSDLLDDVYHYQAVNLIGLRQYTDAFPLMERYLKSVENIGDNNVKAKAYMRMANLALNLEAYEDL
RNYGEKALSLSQSSDKKVYCFSLILIAFADLKEYELKEAERGFKSSKLFCDQNELPLFGFMSGKGLAEIAMKMDDFESAE
MQLNEVLAGYIKYGYKAEIISVHALLAKTNLRLKKYSQAEEFANKVMGLSDEPSHTEYKAIASKVLSQRYLESKQYKLAH
DYLESHQHYSNLIFDDTKAKANAYQMAKFKHQEQAREIALLNQERQLVETQKELDRSDRTNNVMIMTMLAGSVIFLSLFL
LYSHRQKVRYRRLALTDRLTSVYNRGAGQDFAENEFVQVSMRKADYAVIVFDLDLFKNINDSFGHATGDWTLKHVVSVIR
PLIRDSDIFTRMGGEEFALFLPYSSEQTALKIAERCKLAVAAIDTKYSGHVFNISASFGVSCSTSEDLSLDPLLKRADIA
LYASKHSGRNRVTLYTPELKLQRPTDETQRSLVFN

Sequences:

>Translated_595_residues
MRTVISIFFLLTLYASFPLFGGQGDFDDVLVKIEKALRASPEQVESLINRLLVSWDELSKEQQIKLIVYQAIRKSYNGEY
RSSQNFLERVKEYRVRSDLLDDVYHYQAVNLIGLRQYTDAFPLMERYLKSVENIGDNNVKAKAYMRMANLALNLEAYEDL
RNYGEKALSLSQSSDKKVYCFSLILIAFADLKEYELKEAERGFKSSKLFCDQNELPLFGFMSGKGLAEIAMKMDDFESAE
MQLNEVLAGYIKYGYKAEIISVHALLAKTNLRLKKYSQAEEFANKVMGLSDEPSHTEYKAIASKVLSQRYLESKQYKLAH
DYLESHQHYSNLIFDDTKAKANAYQMAKFKHQEQAREIALLNQERQLVETQKELDRSDRTNNVMIMTMLAGSVIFLSLFL
LYSHRQKVRYRRLALTDRLTSVYNRGAGQDFAENEFVQVSMRKADYAVIVFDLDLFKNINDSFGHATGDWTLKHVVSVIR
PLIRDSDIFTRMGGEEFALFLPYSSEQTALKIAERCKLAVAAIDTKYSGHVFNISASFGVSCSTSEDLSLDPLLKRADIA
LYASKHSGRNRVTLYTPELKLQRPTDETQRSLVFN
>Mature_595_residues
MRTVISIFFLLTLYASFPLFGGQGDFDDVLVKIEKALRASPEQVESLINRLLVSWDELSKEQQIKLIVYQAIRKSYNGEY
RSSQNFLERVKEYRVRSDLLDDVYHYQAVNLIGLRQYTDAFPLMERYLKSVENIGDNNVKAKAYMRMANLALNLEAYEDL
RNYGEKALSLSQSSDKKVYCFSLILIAFADLKEYELKEAERGFKSSKLFCDQNELPLFGFMSGKGLAEIAMKMDDFESAE
MQLNEVLAGYIKYGYKAEIISVHALLAKTNLRLKKYSQAEEFANKVMGLSDEPSHTEYKAIASKVLSQRYLESKQYKLAH
DYLESHQHYSNLIFDDTKAKANAYQMAKFKHQEQAREIALLNQERQLVETQKELDRSDRTNNVMIMTMLAGSVIFLSLFL
LYSHRQKVRYRRLALTDRLTSVYNRGAGQDFAENEFVQVSMRKADYAVIVFDLDLFKNINDSFGHATGDWTLKHVVSVIR
PLIRDSDIFTRMGGEEFALFLPYSSEQTALKIAERCKLAVAAIDTKYSGHVFNISASFGVSCSTSEDLSLDPLLKRADIA
LYASKHSGRNRVTLYTPELKLQRPTDETQRSLVFN

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=162, Percent_Identity=36.4197530864198, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082007, Length=161, Percent_Identity=39.7515527950311, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081881, Length=156, Percent_Identity=37.1794871794872, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=31.9277108433735, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786584, Length=192, Percent_Identity=29.6875, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=34.1463414634146, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1787541, Length=182, Percent_Identity=31.8681318681319, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787816, Length=126, Percent_Identity=34.9206349206349, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=31.4814814814815, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788085, Length=191, Percent_Identity=30.3664921465969, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=182, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787056, Length=132, Percent_Identity=35.6060606060606, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 68323; Mature: 68323

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVISIFFLLTLYASFPLFGGQGDFDDVLVKIEKALRASPEQVESLINRLLVSWDELSK
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
EQQIKLIVYQAIRKSYNGEYRSSQNFLERVKEYRVRSDLLDDVYHYQAVNLIGLRQYTDA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPLMERYLKSVENIGDNNVKAKAYMRMANLALNLEAYEDLRNYGEKALSLSQSSDKKVYC
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
FSLILIAFADLKEYELKEAERGFKSSKLFCDQNELPLFGFMSGKGLAEIAMKMDDFESAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHCCCCHHH
MQLNEVLAGYIKYGYKAEIISVHALLAKTNLRLKKYSQAEEFANKVMGLSDEPSHTEYKA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
IASKVLSQRYLESKQYKLAHDYLESHQHYSNLIFDDTKAKANAYQMAKFKHQEQAREIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHHHHHHHHH
LNQERQLVETQKELDRSDRTNNVMIMTMLAGSVIFLSLFLLYSHRQKVRYRRLALTDRLT
HHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVYNRGAGQDFAENEFVQVSMRKADYAVIVFDLDLFKNINDSFGHATGDWTLKHVVSVIR
HHHHCCCCCCCCCCCEEEEEEECCCEEEEEEEHHHHHCCCHHCCCCCCCHHHHHHHHHHH
PLIRDSDIFTRMGGEEFALFLPYSSEQTALKIAERCKLAVAAIDTKYSGHVFNISASFGV
HHHCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCC
SCSTSEDLSLDPLLKRADIALYASKHSGRNRVTLYTPELKLQRPTDETQRSLVFN
CCCCCCCCCCCHHHHHCCEEEEEECCCCCCEEEEECCCEEEECCCCHHHHCCCCC
>Mature Secondary Structure
MRTVISIFFLLTLYASFPLFGGQGDFDDVLVKIEKALRASPEQVESLINRLLVSWDELSK
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
EQQIKLIVYQAIRKSYNGEYRSSQNFLERVKEYRVRSDLLDDVYHYQAVNLIGLRQYTDA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPLMERYLKSVENIGDNNVKAKAYMRMANLALNLEAYEDLRNYGEKALSLSQSSDKKVYC
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
FSLILIAFADLKEYELKEAERGFKSSKLFCDQNELPLFGFMSGKGLAEIAMKMDDFESAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHCCCCHHH
MQLNEVLAGYIKYGYKAEIISVHALLAKTNLRLKKYSQAEEFANKVMGLSDEPSHTEYKA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
IASKVLSQRYLESKQYKLAHDYLESHQHYSNLIFDDTKAKANAYQMAKFKHQEQAREIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHHHHHHHHH
LNQERQLVETQKELDRSDRTNNVMIMTMLAGSVIFLSLFLLYSHRQKVRYRRLALTDRLT
HHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVYNRGAGQDFAENEFVQVSMRKADYAVIVFDLDLFKNINDSFGHATGDWTLKHVVSVIR
HHHHCCCCCCCCCCCEEEEEEECCCEEEEEEEHHHHHCCCHHCCCCCCCHHHHHHHHHHH
PLIRDSDIFTRMGGEEFALFLPYSSEQTALKIAERCKLAVAAIDTKYSGHVFNISASFGV
HHHCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCC
SCSTSEDLSLDPLLKRADIALYASKHSGRNRVTLYTPELKLQRPTDETQRSLVFN
CCCCCCCCCCCHHHHHCCEEEEEECCCCCCEEEEECCCEEEECCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]