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The map label for this gene is pheC [H]

Identifier: 157961067

GI number: 157961067

Start: 1511101

End: 1513311

Strand: Direct

Name: pheC [H]

Synonym: Spea_1239

Alternate gene names: 157961067

Gene position: 1511101-1513311 (Clockwise)

Preceding gene: 157961066

Following gene: 157961068

Centisome position: 29.2

GC content: 43.92

Gene sequence:

>2211_bases
ATGAGCAGTAAAACGGATACTATAGAGCCAGAAGCGAACGATACCGAGCAACAAAAACCAAAGCAGAAGATGAGTATGTC
GACTCTGGTTTTATTGTCGTTTGCGGCAGGTATTATTGCAGGGCTATTTTTTGGTGAGATGTTGGCGTGGATGTCTGTCA
TTGGTGATGCATTTATTAAACTGCTGCAGATGACGATTATTCCCTACATCATAGTGTCCTTGGTCTCGAGCCTCGGTAGT
TTGACCATGGAACAGGCTAAATCTTTGGGGGTGAAGGTTGGTAAGCTAATGTTGGTGATCTGGGCCTTTGGTCTACTGAC
TATGTATCTTATCAAGTACACCTTTCCCGACTGGCAGGCGGGGGAATTTTTTAGCTTAACAGCTCTAGAAGATCCCAATT
CGGTAAACTTACTCGATATCTATATTCCTTCCAACCCGTTCTTTTCATTGTCGAACAGTTATATCCCTGCAATTGTGCTG
TTCTGTGTCGCCACGGGTATTGCGCTGATCTCTATCGATAATAAAGACTCGCTTATGAAGCCGATGCAGCTGCTTGGAGA
GTCGTTTAATAAGGTGACTCAAAGCATTGTTAAATTAATGCCGATTGGTATCTTCGCCATGACAGCGGCGACAGCGGGCA
CCATGGACTTTGACGAGTTTCAAAAGTTACAGGTCTATTTTGTAGCCCATGTGGTGATGACTATTATCCTGACTTACTGG
GTCTTGCCGGGTATTTTAATGGTGATCACTCCCTTCTCTTATCGAGATATCACGGGGATTGCTAAAGATGCGATGATCAC
GGCATTTGCTGCGGGCAATATTTTTATCGTTATTCCTATTCTCATTGAGCGTACCAAAGAGTTATTCCATAAATATAATA
TCGGCAGCCAGCAGAGTGATGACTATGCCAACATCATTATTCCTGTTGTGTTTAGCTTCCCAAATCTAGGCAAATTACTC
ACCATAGTCTTTGTGCTTTTTGCGGCTTGGTTTTCAGGGGCTGAACTGGATTTTTTAACTTACTTGCCCATGTCATTAAA
TGGTTTAGTGAGCCTGTTTGGTAGTGTTTATTTGACCATACCTATGCTACTTGATTCTCTAGAGCTTTCCTCCGATCTGT
TTCAGTTGTATATGGTCTCTAGTCTGTTCACCAGTCGTTTTACCTCTTTGCTTGCTGCGATGAATATTTTCATCTTGGCT
ATAGGCGGTACGGCGATGTTGGTCGGTATCGCTAAAGTGAGCATGAAGCGATTAGCAATTGTAAGCCTACTGACTCCAGT
GGTGTTCGGTGTGAGTTTACTGGCAACGAGCTGGTTACTGAGCTCTATCGTCGATACCGAGTATGAGATGGATGAAGTCG
TGGCGCAGATGAGTGCGGCAGAGAAAGTGCCTGATCAAGTTACCGCCTATAACTGGGCTGACTTAGCTCAAGCTGATGGA
CCTCGCAACATGCAGCAGATTAGAGAGAGCGGTGTGATCAGAGTCGGCTACAACCCGACGCAGGTTCCTTTCTCTTTTTA
TAATGCCGATCAACAGCTAGTAGGATTTGATGTTGAGCTAATGAAAAAGTTAGCGCTAGAGTTAGAGCTTAAAATTGCAT
TTGTACCTTATACCTTCAGTAACGTTTTAGAGGGGATCAATCAAGGTCAGTTTGATATTGCGATATCGGGTTTGCAGATG
ACAACCAAGCGAATCGAGCTGGTGGGCTTTACCACTCCTGTGCTCGACCTGCACTACGCGTTTGTGGTGAAGGATCATCG
CGTTGATGAGTTTAAAACTGACAAGTTAATTCGTGATGCCGACAAGATTCGTATCGCCACAGTGGGTCGTTATTCAATTA
TTCCGCAGTTAGAAGAGAAGTTTCCCAATATCGAGTTTGTGACTATTCAGTCGGACCGATTGTTTTTTGAAGATGACGGC
AAGACCTGGGATGGGCTTATGATAAGTCTCGAAGCGGGTAAAACTTGGACAATCTTATACCCAGATTACGCCACACTTTA
TAATCGTGAAGAGATTAAGTCGTTTCCCGCTTCCTACGCAGTGGCTCGTGACAACGCCTCGCTACAAACCTTTTTAAATA
GCTGGCTTGAGCTACAAAAGTCATCAGGTTATGTCGACAAACTGTATGGTTATTGGATTTTAGGTGAGAATGCCAAGCCC
CAAAAGCCACGCTGGTCAGTAATAAAAGATGTGTTACATTGGGTTGATTAA

Upstream 100 bases:

>100_bases
CCCGAGAGAAAAGTCGAGCAATACATAGCCTGCTACCGAGAAGCCATTCAGGATTGCCAATGTGCTTGTTCATCAGTGCA
GACATTACACGGAGACAGTA

Downstream 100 bases:

>100_bases
AAATAATAATAACAACGCGATAGTCATAAATGACAAGGAGTATTGTTGGTGAAAATACTTACTGCTGTATTACTCATGAT
GGTCACTCAATCTGCGGCCT

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 736; Mature: 735

Protein sequence:

>736_residues
MSSKTDTIEPEANDTEQQKPKQKMSMSTLVLLSFAAGIIAGLFFGEMLAWMSVIGDAFIKLLQMTIIPYIIVSLVSSLGS
LTMEQAKSLGVKVGKLMLVIWAFGLLTMYLIKYTFPDWQAGEFFSLTALEDPNSVNLLDIYIPSNPFFSLSNSYIPAIVL
FCVATGIALISIDNKDSLMKPMQLLGESFNKVTQSIVKLMPIGIFAMTAATAGTMDFDEFQKLQVYFVAHVVMTIILTYW
VLPGILMVITPFSYRDITGIAKDAMITAFAAGNIFIVIPILIERTKELFHKYNIGSQQSDDYANIIIPVVFSFPNLGKLL
TIVFVLFAAWFSGAELDFLTYLPMSLNGLVSLFGSVYLTIPMLLDSLELSSDLFQLYMVSSLFTSRFTSLLAAMNIFILA
IGGTAMLVGIAKVSMKRLAIVSLLTPVVFGVSLLATSWLLSSIVDTEYEMDEVVAQMSAAEKVPDQVTAYNWADLAQADG
PRNMQQIRESGVIRVGYNPTQVPFSFYNADQQLVGFDVELMKKLALELELKIAFVPYTFSNVLEGINQGQFDIAISGLQM
TTKRIELVGFTTPVLDLHYAFVVKDHRVDEFKTDKLIRDADKIRIATVGRYSIIPQLEEKFPNIEFVTIQSDRLFFEDDG
KTWDGLMISLEAGKTWTILYPDYATLYNREEIKSFPASYAVARDNASLQTFLNSWLELQKSSGYVDKLYGYWILGENAKP
QKPRWSVIKDVLHWVD

Sequences:

>Translated_736_residues
MSSKTDTIEPEANDTEQQKPKQKMSMSTLVLLSFAAGIIAGLFFGEMLAWMSVIGDAFIKLLQMTIIPYIIVSLVSSLGS
LTMEQAKSLGVKVGKLMLVIWAFGLLTMYLIKYTFPDWQAGEFFSLTALEDPNSVNLLDIYIPSNPFFSLSNSYIPAIVL
FCVATGIALISIDNKDSLMKPMQLLGESFNKVTQSIVKLMPIGIFAMTAATAGTMDFDEFQKLQVYFVAHVVMTIILTYW
VLPGILMVITPFSYRDITGIAKDAMITAFAAGNIFIVIPILIERTKELFHKYNIGSQQSDDYANIIIPVVFSFPNLGKLL
TIVFVLFAAWFSGAELDFLTYLPMSLNGLVSLFGSVYLTIPMLLDSLELSSDLFQLYMVSSLFTSRFTSLLAAMNIFILA
IGGTAMLVGIAKVSMKRLAIVSLLTPVVFGVSLLATSWLLSSIVDTEYEMDEVVAQMSAAEKVPDQVTAYNWADLAQADG
PRNMQQIRESGVIRVGYNPTQVPFSFYNADQQLVGFDVELMKKLALELELKIAFVPYTFSNVLEGINQGQFDIAISGLQM
TTKRIELVGFTTPVLDLHYAFVVKDHRVDEFKTDKLIRDADKIRIATVGRYSIIPQLEEKFPNIEFVTIQSDRLFFEDDG
KTWDGLMISLEAGKTWTILYPDYATLYNREEIKSFPASYAVARDNASLQTFLNSWLELQKSSGYVDKLYGYWILGENAKP
QKPRWSVIKDVLHWVD
>Mature_735_residues
SSKTDTIEPEANDTEQQKPKQKMSMSTLVLLSFAAGIIAGLFFGEMLAWMSVIGDAFIKLLQMTIIPYIIVSLVSSLGSL
TMEQAKSLGVKVGKLMLVIWAFGLLTMYLIKYTFPDWQAGEFFSLTALEDPNSVNLLDIYIPSNPFFSLSNSYIPAIVLF
CVATGIALISIDNKDSLMKPMQLLGESFNKVTQSIVKLMPIGIFAMTAATAGTMDFDEFQKLQVYFVAHVVMTIILTYWV
LPGILMVITPFSYRDITGIAKDAMITAFAAGNIFIVIPILIERTKELFHKYNIGSQQSDDYANIIIPVVFSFPNLGKLLT
IVFVLFAAWFSGAELDFLTYLPMSLNGLVSLFGSVYLTIPMLLDSLELSSDLFQLYMVSSLFTSRFTSLLAAMNIFILAI
GGTAMLVGIAKVSMKRLAIVSLLTPVVFGVSLLATSWLLSSIVDTEYEMDEVVAQMSAAEKVPDQVTAYNWADLAQADGP
RNMQQIRESGVIRVGYNPTQVPFSFYNADQQLVGFDVELMKKLALELELKIAFVPYTFSNVLEGINQGQFDIAISGLQMT
TKRIELVGFTTPVLDLHYAFVVKDHRVDEFKTDKLIRDADKIRIATVGRYSIIPQLEEKFPNIEFVTIQSDRLFFEDDGK
TWDGLMISLEAGKTWTILYPDYATLYNREEIKSFPASYAVARDNASLQTFLNSWLELQKSSGYVDKLYGYWILGENAKPQ
KPRWSVIKDVLHWVD

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1787085, Length=225, Percent_Identity=24.4444444444444, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: 1180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 82313; Mature: 82182

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKTDTIEPEANDTEQQKPKQKMSMSTLVLLSFAAGIIAGLFFGEMLAWMSVIGDAFIK
CCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQMTIIPYIIVSLVSSLGSLTMEQAKSLGVKVGKLMLVIWAFGLLTMYLIKYTFPDWQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GEFFSLTALEDPNSVNLLDIYIPSNPFFSLSNSYIPAIVLFCVATGIALISIDNKDSLMK
CCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCEEEEEECCCHHHHH
PMQLLGESFNKVTQSIVKLMPIGIFAMTAATAGTMDFDEFQKLQVYFVAHVVMTIILTYW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLPGILMVITPFSYRDITGIAKDAMITAFAAGNIFIVIPILIERTKELFHKYNIGSQQSD
HHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHCCCCCCCCC
DYANIIIPVVFSFPNLGKLLTIVFVLFAAWFSGAELDFLTYLPMSLNGLVSLFGSVYLTI
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEECCHHHHHHHHHHHHHHHHH
PMLLDSLELSSDLFQLYMVSSLFTSRFTSLLAAMNIFILAIGGTAMLVGIAKVSMKRLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHH
VSLLTPVVFGVSLLATSWLLSSIVDTEYEMDEVVAQMSAAEKVPDQVTAYNWADLAQADG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHCCC
PRNMQQIRESGVIRVGYNPTQVPFSFYNADQQLVGFDVELMKKLALELELKIAFVPYTFS
CCHHHHHHHCCEEEECCCCCCCCCCEECCCCHHCCCCHHHHHHHHHEEEEEEEEECCCHH
NVLEGINQGQFDIAISGLQMTTKRIELVGFTTPVLDLHYAFVVKDHRVDEFKTDKLIRDA
HHHHHCCCCCEEEEEECHHHHHHHEEEEECCCHHHHHHEEEEEECCCCCHHHHHHHHHCC
DKIRIATVGRYSIIPQLEEKFPNIEFVTIQSDRLFFEDDGKTWDGLMISLEAGKTWTILY
CCEEEEEECCHHCCCHHHHHCCCEEEEEEECCEEEEECCCCCCCCEEEEEECCCEEEEEC
PDYATLYNREEIKSFPASYAVARDNASLQTFLNSWLELQKSSGYVDKLYGYWILGENAKP
CCHHHHCCHHHHHHCCCHHEEECCCCHHHHHHHHHHHHHHCCCCHHHHCEEEEECCCCCC
QKPRWSVIKDVLHWVD
CCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSKTDTIEPEANDTEQQKPKQKMSMSTLVLLSFAAGIIAGLFFGEMLAWMSVIGDAFIK
CCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQMTIIPYIIVSLVSSLGSLTMEQAKSLGVKVGKLMLVIWAFGLLTMYLIKYTFPDWQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GEFFSLTALEDPNSVNLLDIYIPSNPFFSLSNSYIPAIVLFCVATGIALISIDNKDSLMK
CCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCEEEEEECCCHHHHH
PMQLLGESFNKVTQSIVKLMPIGIFAMTAATAGTMDFDEFQKLQVYFVAHVVMTIILTYW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLPGILMVITPFSYRDITGIAKDAMITAFAAGNIFIVIPILIERTKELFHKYNIGSQQSD
HHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHCCCCCCCCC
DYANIIIPVVFSFPNLGKLLTIVFVLFAAWFSGAELDFLTYLPMSLNGLVSLFGSVYLTI
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEECCHHHHHHHHHHHHHHHHH
PMLLDSLELSSDLFQLYMVSSLFTSRFTSLLAAMNIFILAIGGTAMLVGIAKVSMKRLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHH
VSLLTPVVFGVSLLATSWLLSSIVDTEYEMDEVVAQMSAAEKVPDQVTAYNWADLAQADG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHCCC
PRNMQQIRESGVIRVGYNPTQVPFSFYNADQQLVGFDVELMKKLALELELKIAFVPYTFS
CCHHHHHHHCCEEEECCCCCCCCCCEECCCCHHCCCCHHHHHHHHHEEEEEEEEECCCHH
NVLEGINQGQFDIAISGLQMTTKRIELVGFTTPVLDLHYAFVVKDHRVDEFKTDKLIRDA
HHHHHCCCCCEEEEEECHHHHHHHEEEEECCCHHHHHHEEEEEECCCCCHHHHHHHHHCC
DKIRIATVGRYSIIPQLEEKFPNIEFVTIQSDRLFFEDDGKTWDGLMISLEAGKTWTILY
CCEEEEEECCHHCCCHHHHHCCCEEEEEEECCEEEEECCCCCCCCEEEEEECCCEEEEEC
PDYATLYNREEIKSFPASYAVARDNASLQTFLNSWLELQKSSGYVDKLYGYWILGENAKP
CCHHHHCCHHHHHHCCCHHEEECCCCHHHHHHHHHHHHHHCCCCHHHHCEEEEECCCCCC
QKPRWSVIKDVLHWVD
CCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]