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The map label for this gene is ribD [H]

Identifier: 157960990

GI number: 157960990

Start: 1407589

End: 1408710

Strand: Direct

Name: ribD [H]

Synonym: Spea_1162

Alternate gene names: 157960990

Gene position: 1407589-1408710 (Clockwise)

Preceding gene: 157960989

Following gene: 157960991

Centisome position: 27.2

GC content: 51.25

Gene sequence:

>1122_bases
ATGTGGTCTATCGAAGACAGTCAAATGATGAGCCTTGCCATTGAATTGGCACAAAAGGGCATGTACACCACTCGTCCAAA
TCCTAGCGTGGGGAGTGTTATCGTTAAAGACGGTGAGATCGTTGGTGAGGGCTACCATATTCGAGCCGGCGGTCCTCATG
CGGAAGTTTACGCCTTGAATATGGCGGGCAGTGACGCTAAAGGCGCCACCGCCTACGTAACACTTGAACCTTGTAGCCAT
TACGGTCGTACGCCACCTTGCGCCAAGGCGTTAATCGAACACGGCGTCAGCCGAGTGGTTATTGCGGTGACCGACCCGAA
TCCTGAAGTCTCTGGCCGTGGTATTGCTATGTTGCGGGATGCGGGTATTCGAGTCGATGTTGGGCTGATGACCGAAGAAG
CTAAGCAGGTCAACCTAGGCTTTTTAAAGCGTATGGAAAAAGGCCTGCCTTGGGTGACAGTTAAACTTGCCGCCAGTCTC
GATGGCAAAACGGCCTTGTCTAACGGCGTATCCAAGTGGATTACCGGCCCTGAAGCCCGCCGTGATGTACAGCGTCTTCG
TGCTCGCCATTGCGCTTTAGTCACTGGCGTTGAAACCATACTTGCCGATGACCCCAGTTTAAATGTGCGTCACAGTGAGT
TAGGCTCACTTGCAAGTCAACTCGCCCCAGCCGAAATTCACCAGCCACTTAGGGTGGTATTAGACAGTCAGGCGCGTTTA
GGTCATGAATTAAACCTGTTTAAAATCGACAGTCCGATTTTACTGGTGTCGACTCAAGCTTATCCCGAGAGCGTGCAGGC
CGCATGGCCGCCTCATGTGCAGAGTCAGGTATTAGCGGCGGTTGATTCACGTATCGACTTAAATGCGTTATTAAGCCTAC
TGGGTGAGAGTTGTAACTCTGTGTTGGTTGAAGCTGGTGCGACGCTTGCGGGGGCCTTTGTTAATCAAGGGCTAGCCGAT
GAGATTGTACTGTATCAGGCGATGAAGATTTTAGGCTCGCAAGGGCGAAACCTGCTGACACTTGATGATTTTCAAGCCAT
GTCAGAGGTGCCAAAGATTAACCTAATCGATGAGCGCAAAGTGGGGCCAGACACCCGCTTAACGTTAAGAGTGAGTAATT
AA

Upstream 100 bases:

>100_bases
TTGGTGAAGCGATCGCTAAACTGCAAAAATAAACTACGCAACCGGGGCTAAGCGCTGCGCCTAGCCCTTCATCAATCGAA
CAATCGGAATTGCCGCCAAT

Downstream 100 bases:

>100_bases
TTTATGTTTACTGGGATTATTGAATCAGTCGGACACCTACGAAAAGTTGAGCGTCGCGGCGATGATATTCGCTTAACGGT
AGCCAGTGGTAAACTGGATC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MWSIEDSQMMSLAIELAQKGMYTTRPNPSVGSVIVKDGEIVGEGYHIRAGGPHAEVYALNMAGSDAKGATAYVTLEPCSH
YGRTPPCAKALIEHGVSRVVIAVTDPNPEVSGRGIAMLRDAGIRVDVGLMTEEAKQVNLGFLKRMEKGLPWVTVKLAASL
DGKTALSNGVSKWITGPEARRDVQRLRARHCALVTGVETILADDPSLNVRHSELGSLASQLAPAEIHQPLRVVLDSQARL
GHELNLFKIDSPILLVSTQAYPESVQAAWPPHVQSQVLAAVDSRIDLNALLSLLGESCNSVLVEAGATLAGAFVNQGLAD
EIVLYQAMKILGSQGRNLLTLDDFQAMSEVPKINLIDERKVGPDTRLTLRVSN

Sequences:

>Translated_373_residues
MWSIEDSQMMSLAIELAQKGMYTTRPNPSVGSVIVKDGEIVGEGYHIRAGGPHAEVYALNMAGSDAKGATAYVTLEPCSH
YGRTPPCAKALIEHGVSRVVIAVTDPNPEVSGRGIAMLRDAGIRVDVGLMTEEAKQVNLGFLKRMEKGLPWVTVKLAASL
DGKTALSNGVSKWITGPEARRDVQRLRARHCALVTGVETILADDPSLNVRHSELGSLASQLAPAEIHQPLRVVLDSQARL
GHELNLFKIDSPILLVSTQAYPESVQAAWPPHVQSQVLAAVDSRIDLNALLSLLGESCNSVLVEAGATLAGAFVNQGLAD
EIVLYQAMKILGSQGRNLLTLDDFQAMSEVPKINLIDERKVGPDTRLTLRVSN
>Mature_373_residues
MWSIEDSQMMSLAIELAQKGMYTTRPNPSVGSVIVKDGEIVGEGYHIRAGGPHAEVYALNMAGSDAKGATAYVTLEPCSH
YGRTPPCAKALIEHGVSRVVIAVTDPNPEVSGRGIAMLRDAGIRVDVGLMTEEAKQVNLGFLKRMEKGLPWVTVKLAASL
DGKTALSNGVSKWITGPEARRDVQRLRARHCALVTGVETILADDPSLNVRHSELGSLASQLAPAEIHQPLRVVLDSQARL
GHELNLFKIDSPILLVSTQAYPESVQAAWPPHVQSQVLAAVDSRIDLNALLSLLGESCNSVLVEAGATLAGAFVNQGLAD
EIVLYQAMKILGSQGRNLLTLDDFQAMSEVPKINLIDERKVGPDTRLTLRVSN

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=368, Percent_Identity=51.3586956521739, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40044; Mature: 40044

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSIEDSQMMSLAIELAQKGMYTTRPNPSVGSVIVKDGEIVGEGYHIRAGGPHAEVYALN
CCCCCHHHHHHHHHHHHHCCCEECCCCCCCCEEEEECCEEECCCEEEECCCCCEEEEEEE
MAGSDAKGATAYVTLEPCSHYGRTPPCAKALIEHGVSRVVIAVTDPNPEVSGRGIAMLRD
ECCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEC
AGIRVDVGLMTEEAKQVNLGFLKRMEKGLPWVTVKLAASLDGKTALSNGVSKWITGPEAR
CCCEEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHCHHHHCCCHHHH
RDVQRLRARHCALVTGVETILADDPSLNVRHSELGSLASQLAPAEIHQPLRVVLDSQARL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHC
GHELNLFKIDSPILLVSTQAYPESVQAAWPPHVQSQVLAAVDSRIDLNALLSLLGESCNS
CCCEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VLVEAGATLAGAFVNQGLADEIVLYQAMKILGSQGRNLLTLDDFQAMSEVPKINLIDERK
HHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCEEEECCCC
VGPDTRLTLRVSN
CCCCCEEEEEECC
>Mature Secondary Structure
MWSIEDSQMMSLAIELAQKGMYTTRPNPSVGSVIVKDGEIVGEGYHIRAGGPHAEVYALN
CCCCCHHHHHHHHHHHHHCCCEECCCCCCCCEEEEECCEEECCCEEEECCCCCEEEEEEE
MAGSDAKGATAYVTLEPCSHYGRTPPCAKALIEHGVSRVVIAVTDPNPEVSGRGIAMLRD
ECCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEC
AGIRVDVGLMTEEAKQVNLGFLKRMEKGLPWVTVKLAASLDGKTALSNGVSKWITGPEAR
CCCEEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHCHHHHCCCHHHH
RDVQRLRARHCALVTGVETILADDPSLNVRHSELGSLASQLAPAEIHQPLRVVLDSQARL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHC
GHELNLFKIDSPILLVSTQAYPESVQAAWPPHVQSQVLAAVDSRIDLNALLSLLGESCNS
CCCEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VLVEAGATLAGAFVNQGLADEIVLYQAMKILGSQGRNLLTLDDFQAMSEVPKINLIDERK
HHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCEEEECCCC
VGPDTRLTLRVSN
CCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]