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The map label for this gene is aroF [H]

Identifier: 157960881

GI number: 157960881

Start: 1275021

End: 1276112

Strand: Direct

Name: aroF [H]

Synonym: Spea_1053

Alternate gene names: 157960881

Gene position: 1275021-1276112 (Clockwise)

Preceding gene: 157960880

Following gene: 157960882

Centisome position: 24.64

GC content: 46.34

Gene sequence:

>1092_bases
ATGCAACAAGATACAATTAACAATGTTCATATCAGTTCAGAGCAAGTACTAGTCACTCCAGAGGAGTTAAAGCGTGAGCT
TCCTCTTTCCACCCATGCTTACCAGTACGTTCTCAATGCTCGCAAGACAGTATCTGACATTGTGCATAAACGTGATAATC
GCGTATTGGTGATTTCAGGTCCTTGCTCTATCCATGATATTGATGCTGCCAAAGAGTACGCGCTAAAGCTTAAGAAGTTA
CATGATGAACTTGGTGATCAGTTTTTTGTGTTGATGCGAGTTTACTTCGAAAAGCCGCGTACTACTGTTGGCTGGAAAGG
AATGATTAACGACCCTGATATGGATGAATCCTTCGATGTGGATAAAGGCTTGAGAAAAGCTCGCGAACTGATGATCTGGC
TTGCTGAACTTGAACTGCCTGTTGCCACTGAGGCGCTCGATCCTATTAGTCCGCAATACATGTCGGAGTTGGTAACTTGG
TCAGCCATTGGCGCACGCACCACTGAGTCACAGACTCACCGTGAAATGGCGTCGGGTCTTTCTATGCCGGTAGGCTTTAA
AAATGGTACCGATGGCAAGCTTGGTGTGGCCATCAATGCATTAGAGTCGGCTGCGAGTAGTCACCGCTTCATGGGTATTA
ACCAGCAAGGTCAGGTCGCACTGCTACAGACCGCAGGTAACCCTGATGGACATGTGATTTTACGTGGCGGCAAAACACCT
AACTATGATGCTGCGAGTGTGGCGGAGTGTGAACAGCAGTTACATGCAGCCAAACTCAGTGCACGATTGATTGTCGATTG
CAGTCATGGTAACTCGTCAAAAGATCATAATAAGCAAAAGCCTGTGTGCGAAGATGTTTTTAACCAGATTGTGGCGGGCA
ATAAGTCTATTATCGGTGTGATGCTAGAAAGCCATTTAAATGCGGGTAAGCAGAGCAGTGACTTGCCGATGGATGAGCTT
GCTTACGGCGTTTCGGTTACAGATGCTTGTATCGACTGGAAAACCACAGAAGCGTTATTACGAACGGGAGCCGATGAGTT
AGCCTCGGTATTACCGACAAGATTTGATATGCTAAAAGTTGCAAACGGCTGA

Upstream 100 bases:

>100_bases
GTTACTTCGGTAATTTGATTTAATAATGAGTTGAGACGTTCTTCAGTGTAGAAAAGGTCGTTGACGCGAGAAGCGGATTA
GAGATAGGCAGGTGGTAATT

Downstream 100 bases:

>100_bases
TGGAAGAAACACAGATGAATGAGAAGACTACCGCAGAGCTTGAAAATCTAAGAGGTTTGATTGACGGTGTCGATCAGCAG
TTACTGCACCTGTTACGCAA

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MQQDTINNVHISSEQVLVTPEELKRELPLSTHAYQYVLNARKTVSDIVHKRDNRVLVISGPCSIHDIDAAKEYALKLKKL
HDELGDQFFVLMRVYFEKPRTTVGWKGMINDPDMDESFDVDKGLRKARELMIWLAELELPVATEALDPISPQYMSELVTW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGKLGVAINALESAASSHRFMGINQQGQVALLQTAGNPDGHVILRGGKTP
NYDAASVAECEQQLHAAKLSARLIVDCSHGNSSKDHNKQKPVCEDVFNQIVAGNKSIIGVMLESHLNAGKQSSDLPMDEL
AYGVSVTDACIDWKTTEALLRTGADELASVLPTRFDMLKVANG

Sequences:

>Translated_363_residues
MQQDTINNVHISSEQVLVTPEELKRELPLSTHAYQYVLNARKTVSDIVHKRDNRVLVISGPCSIHDIDAAKEYALKLKKL
HDELGDQFFVLMRVYFEKPRTTVGWKGMINDPDMDESFDVDKGLRKARELMIWLAELELPVATEALDPISPQYMSELVTW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGKLGVAINALESAASSHRFMGINQQGQVALLQTAGNPDGHVILRGGKTP
NYDAASVAECEQQLHAAKLSARLIVDCSHGNSSKDHNKQKPVCEDVFNQIVAGNKSIIGVMLESHLNAGKQSSDLPMDEL
AYGVSVTDACIDWKTTEALLRTGADELASVLPTRFDMLKVANG
>Mature_363_residues
MQQDTINNVHISSEQVLVTPEELKRELPLSTHAYQYVLNARKTVSDIVHKRDNRVLVISGPCSIHDIDAAKEYALKLKKL
HDELGDQFFVLMRVYFEKPRTTVGWKGMINDPDMDESFDVDKGLRKARELMIWLAELELPVATEALDPISPQYMSELVTW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGKLGVAINALESAASSHRFMGINQQGQVALLQTAGNPDGHVILRGGKTP
NYDAASVAECEQQLHAAKLSARLIVDCSHGNSSKDHNKQKPVCEDVFNQIVAGNKSIIGVMLESHLNAGKQSSDLPMDEL
AYGVSVTDACIDWKTTEALLRTGADELASVLPTRFDMLKVANG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=354, Percent_Identity=62.1468926553672, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1786969, Length=348, Percent_Identity=52.2988505747126, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1787996, Length=339, Percent_Identity=48.0825958702065, Blast_Score=340, Evalue=9e-95,
Organism=Saccharomyces cerevisiae, GI6319726, Length=363, Percent_Identity=50.4132231404959, Blast_Score=354, Evalue=1e-98,
Organism=Saccharomyces cerevisiae, GI6320240, Length=333, Percent_Identity=48.948948948949, Blast_Score=337, Evalue=2e-93,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39866; Mature: 39866

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQDTINNVHISSEQVLVTPEELKRELPLSTHAYQYVLNARKTVSDIVHKRDNRVLVISG
CCCCCCCCEEECCCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PCSIHDIDAAKEYALKLKKLHDELGDQFFVLMRVYFEKPRTTVGWKGMINDPDMDESFDV
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
DKGLRKARELMIWLAELELPVATEALDPISPQYMSELVTWSAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SMPVGFKNGTDGKLGVAINALESAASSHRFMGINQQGQVALLQTAGNPDGHVILRGGKTP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCEEEEEECCCCCCEEEEECCCCC
NYDAASVAECEQQLHAAKLSARLIVDCSHGNSSKDHNKQKPVCEDVFNQIVAGNKSIIGV
CCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
MLESHLNAGKQSSDLPMDELAYGVSVTDACIDWKTTEALLRTGADELASVLPTRFDMLKV
HHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHCCHHHHHHHHCCHHHHHHHHCCHHHHHEE
ANG
CCC
>Mature Secondary Structure
MQQDTINNVHISSEQVLVTPEELKRELPLSTHAYQYVLNARKTVSDIVHKRDNRVLVISG
CCCCCCCCEEECCCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PCSIHDIDAAKEYALKLKKLHDELGDQFFVLMRVYFEKPRTTVGWKGMINDPDMDESFDV
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
DKGLRKARELMIWLAELELPVATEALDPISPQYMSELVTWSAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SMPVGFKNGTDGKLGVAINALESAASSHRFMGINQQGQVALLQTAGNPDGHVILRGGKTP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCEEEEEECCCCCCEEEEECCCCC
NYDAASVAECEQQLHAAKLSARLIVDCSHGNSSKDHNKQKPVCEDVFNQIVAGNKSIIGV
CCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
MLESHLNAGKQSSDLPMDELAYGVSVTDACIDWKTTEALLRTGADELASVLPTRFDMLKV
HHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHCCHHHHHHHHCCHHHHHHHHCCHHHHHEE
ANG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]