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The map label for this gene is estR [H]

Identifier: 157960844

GI number: 157960844

Start: 1238980

End: 1239915

Strand: Direct

Name: estR [H]

Synonym: Spea_1016

Alternate gene names: 157960844

Gene position: 1238980-1239915 (Clockwise)

Preceding gene: 157960843

Following gene: 157960849

Centisome position: 23.94

GC content: 44.23

Gene sequence:

>936_bases
ATGTCATTGGTAATCTATTTTATGAAACATCTCCCCAGTTTAAAAAACCTGTTCTATTTGGTGAATCTGCATCAAGAGCA
GAATTTCAATAGAGCCGCCAAAATCTGCCATGTTAGTCAGTCGACCTTGTCTAGCGGTATTCAAAACCTTGAAGAGCAGT
TGGGGCACCAACTTATTGAACGTGATCATAAATCTTTTATCTTTACCGCTATCGGTGAAGAGGTCGTGATGCGCTCGCGC
AAATTATTGACCGATGTAGATGATCTTGTCGAGCTGGTTAAACACCAGGGCGAGCCTATGACGGGGGAGATTCGTTTAGG
TTGTATTCCAACGATTGCGCCTTTCTTATTGAGTAATGTGGTTCAGCATTGCAAACAGACTTATCCAGACTTAACGCTGT
TTTTAAAAGAAGACACTACAGATAGATTGATAGATGCACTGAGCAAAGGTGAATTAGATCTGTTGTTGTTAGCCCTTCCT
GTAGACACCAGTGGCTTTCATAGCATGAAGGTCGGTATTGATCCGTTCAAGATGGTGGTGCATAAAGATTTAACCGATGA
GATCCACGAGCCGATTGACTATCAAGACCTGCCCGATGAAAGCATCTTCCTACTGCAGGCTGAGCACTGTATTACTGGAC
ATGCGATTACAGCTTGCCAGTTAGGGGAGAGCGTTAAGATTAATCCATTTGCGGCGACGAGTCTGCATACCTTAGTGCAG
ATGGTTAACTGTAAGCTCGGTACCACCTTCTTGCCACAGATGGCAATTGATGCGGGTATTTTAAATAATACCGACCTGAC
GACTATGGCGCCACCGGGGGAAACTCCTTATCGAGATATCGGCCTAGTTTGGCGTCAAACGTCTAGCAGAATTTTGACCT
TTAGAACCTTGGGGTTAGAGATCCAAAAGCTGTTGGGTCAAGAAGACGCGATATAA

Upstream 100 bases:

>100_bases
TTATCTTGTACATTTTTGATTCAGTTCACAAACTAATCAAGTCAGCCCAAGGTTCGCTTGGAGATTTATGGTAGAGTTAG
ATTGAACGATTAGATAAATA

Downstream 100 bases:

>100_bases
TACCAATCAGTATAAATATTTGGTCGCTCAGCGAGAGTTTAGCGGTTCTGAGGCGAGGTCATTAAATGCTCCTCGGTAAC
TGCTCCTGCGTTACTCTACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Esterase operon transcriptional regulator [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSLVIYFMKHLPSLKNLFYLVNLHQEQNFNRAAKICHVSQSTLSSGIQNLEEQLGHQLIERDHKSFIFTAIGEEVVMRSR
KLLTDVDDLVELVKHQGEPMTGEIRLGCIPTIAPFLLSNVVQHCKQTYPDLTLFLKEDTTDRLIDALSKGELDLLLLALP
VDTSGFHSMKVGIDPFKMVVHKDLTDEIHEPIDYQDLPDESIFLLQAEHCITGHAITACQLGESVKINPFAATSLHTLVQ
MVNCKLGTTFLPQMAIDAGILNNTDLTTMAPPGETPYRDIGLVWRQTSSRILTFRTLGLEIQKLLGQEDAI

Sequences:

>Translated_311_residues
MSLVIYFMKHLPSLKNLFYLVNLHQEQNFNRAAKICHVSQSTLSSGIQNLEEQLGHQLIERDHKSFIFTAIGEEVVMRSR
KLLTDVDDLVELVKHQGEPMTGEIRLGCIPTIAPFLLSNVVQHCKQTYPDLTLFLKEDTTDRLIDALSKGELDLLLLALP
VDTSGFHSMKVGIDPFKMVVHKDLTDEIHEPIDYQDLPDESIFLLQAEHCITGHAITACQLGESVKINPFAATSLHTLVQ
MVNCKLGTTFLPQMAIDAGILNNTDLTTMAPPGETPYRDIGLVWRQTSSRILTFRTLGLEIQKLLGQEDAI
>Mature_310_residues
SLVIYFMKHLPSLKNLFYLVNLHQEQNFNRAAKICHVSQSTLSSGIQNLEEQLGHQLIERDHKSFIFTAIGEEVVMRSRK
LLTDVDDLVELVKHQGEPMTGEIRLGCIPTIAPFLLSNVVQHCKQTYPDLTLFLKEDTTDRLIDALSKGELDLLLLALPV
DTSGFHSMKVGIDPFKMVVHKDLTDEIHEPIDYQDLPDESIFLLQAEHCITGHAITACQLGESVKINPFAATSLHTLVQM
VNCKLGTTFLPQMAIDAGILNNTDLTTMAPPGETPYRDIGLVWRQTSSRILTFRTLGLEIQKLLGQEDAI

Specific function: Transcriptional regulator of the esterase operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=278, Percent_Identity=34.8920863309352, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787879, Length=261, Percent_Identity=30.6513409961686, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI157672245, Length=264, Percent_Identity=24.6212121212121, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=22.8571428571429, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI145693105, Length=251, Percent_Identity=23.1075697211155, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790208, Length=155, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI2367136, Length=242, Percent_Identity=23.9669421487603, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788887, Length=292, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787530, Length=145, Percent_Identity=26.8965517241379, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=21.031746031746, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34857; Mature: 34726

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVIYFMKHLPSLKNLFYLVNLHQEQNFNRAAKICHVSQSTLSSGIQNLEEQLGHQLIE
CHHHHHHHHHCCHHHHHEEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDHKSFIFTAIGEEVVMRSRKLLTDVDDLVELVKHQGEPMTGEIRLGCIPTIAPFLLSNV
HHCHHEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHH
VQHCKQTYPDLTLFLKEDTTDRLIDALSKGELDLLLLALPVDTSGFHSMKVGIDPFKMVV
HHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEEEEEEECCCCCCCEEECCCCHHHHHH
HKDLTDEIHEPIDYQDLPDESIFLLQAEHCITGHAITACQLGESVKINPFAATSLHTLVQ
HHHHHHHHHCCCCCCCCCCCCEEEEEECHHHCCCHHHHHHCCCCEEECCCHHHHHHHHHH
MVNCKLGTTFLPQMAIDAGILNNTDLTTMAPPGETPYRDIGLVWRQTSSRILTFRTLGLE
HHHCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHEECCCCEEEEEHHHHHH
IQKLLGQEDAI
HHHHCCCCCCC
>Mature Secondary Structure 
SLVIYFMKHLPSLKNLFYLVNLHQEQNFNRAAKICHVSQSTLSSGIQNLEEQLGHQLIE
HHHHHHHHHCCHHHHHEEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDHKSFIFTAIGEEVVMRSRKLLTDVDDLVELVKHQGEPMTGEIRLGCIPTIAPFLLSNV
HHCHHEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHH
VQHCKQTYPDLTLFLKEDTTDRLIDALSKGELDLLLLALPVDTSGFHSMKVGIDPFKMVV
HHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEEEEEEECCCCCCCEEECCCCHHHHHH
HKDLTDEIHEPIDYQDLPDESIFLLQAEHCITGHAITACQLGESVKINPFAATSLHTLVQ
HHHHHHHHHCCCCCCCCCCCCEEEEEECHHHCCCHHHHHHCCCCEEECCCHHHHHHHHHH
MVNCKLGTTFLPQMAIDAGILNNTDLTTMAPPGETPYRDIGLVWRQTSSRILTFRTLGLE
HHHCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHEECCCCEEEEEHHHHHH
IQKLLGQEDAI
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA