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The map label for this gene is gcp [H]

Identifier: 157960790

GI number: 157960790

Start: 1173970

End: 1174986

Strand: Direct

Name: gcp [H]

Synonym: Spea_0962

Alternate gene names: 157960790

Gene position: 1173970-1174986 (Clockwise)

Preceding gene: 157960785

Following gene: 157960793

Centisome position: 22.69

GC content: 49.85

Gene sequence:

>1017_bases
ATGCGGGTTTTAGGTATAGAAACATCCTGTGATGAAACAGGGATTGCGGTTTATGATGATAAAAAGGGCTTGCTGTCGCA
TGCGCTTTACAGTCAGGTTAAATTGCATGCCGACTATGGTGGGGTTGTGCCGGAGTTGGCCTCTCGCGACCATGTTCGCA
AAATTGTACCTTTAATACGCCAAGCGTTAGCGGATGCTGGCATGACTATCGAGGATATCGATGGTATCGCTTATACCAAA
GGTCCTGGACTGATAGGAGCACTGTTGGTGGGGGCTTGTGTGGGGCGTGCCTTGGCATTTTCATGGGATAAGCCTGCAAT
TGGTGTACATCATATGGAAGGTCACTTGCTAGCTCCTATGCTGGAAGATGACGTACCTGAGTTTCCATTTTTAGCGTTAT
TAGTTTCAGGCGGTCACTCCATGATTGTTGGCGTGGAAGGCATTGGGCGCTATACGGTACTGGGTGAGTCAGTTGATGAC
GCCGCGGGTGAAGCATTCGATAAAACCGCTAAGCTGATGGGGCTCGATTACCCTGGTGGCCCAAGGCTTTCTAAGCTTGC
CGCTAAGGGAGTGCCAAACAGCTATCGTTTCCCACGTCCAATGACTGACAAACCTGGCCTTAATATGAGCTTCTCAGGCC
TTAAAACCTTTGCGGCTAATACTATTGCGGCCGAGCCAAAAGATGAGCAGACGCGTGCCAACATCGCCTGTGCCTTTGAA
GAGGCGGTTGTCGATACGTTAGCAATTAAGTGTAAGCGTGCTTTAAAGCAAACGGGTTATAAGAACCTAGTGATAGCGGG
CGGCGTAAGTGCTAATACTCGACTTCGTTCATCTTTGGCTGAAATGATGCAGGGCCTTGGCGGTAAGGTATACTACCCGC
GTGGTGAGTTCTGTACCGATAACGGCGCAATGATCGCTTATGCGGGCCTGCAGCGTCTTAAAGCGGGACAAGTTGAAGGC
TTGGAAGTAAAAGGGCAGCCAAGATGGCCACTCGATACGCTAGAGCCTGTAGATTAA

Upstream 100 bases:

>100_bases
TATTAGGCGATATTATCCGCAGACCGTGATAGGACTATGGAGTAATTAAAGCACAGCAGGTAGAATTAGCGGTAATTATG
TCAACCGAAGACGAGAAATA

Downstream 100 bases:

>100_bases
GCTTGTAAATTCGATACGAAAACGGCGCTCATTGAGCGCCGTTTTTTATTTCTCAACAGTATATGCTGAAGGTATTAGAA
GCCGTGGTTAGCGTTACTTA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRVLGIETSCDETGIAVYDDKKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALADAGMTIEDIDGIAYTK
GPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPMLEDDVPEFPFLALLVSGGHSMIVGVEGIGRYTVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
EAVVDTLAIKCKRALKQTGYKNLVIAGGVSANTRLRSSLAEMMQGLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQVEG
LEVKGQPRWPLDTLEPVD

Sequences:

>Translated_338_residues
MRVLGIETSCDETGIAVYDDKKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALADAGMTIEDIDGIAYTK
GPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPMLEDDVPEFPFLALLVSGGHSMIVGVEGIGRYTVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
EAVVDTLAIKCKRALKQTGYKNLVIAGGVSANTRLRSSLAEMMQGLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQVEG
LEVKGQPRWPLDTLEPVD
>Mature_338_residues
MRVLGIETSCDETGIAVYDDKKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALADAGMTIEDIDGIAYTK
GPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPMLEDDVPEFPFLALLVSGGHSMIVGVEGIGRYTVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
EAVVDTLAIKCKRALKQTGYKNLVIAGGVSANTRLRSSLAEMMQGLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQVEG
LEVKGQPRWPLDTLEPVD

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=357, Percent_Identity=33.6134453781513, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI8923380, Length=339, Percent_Identity=33.3333333333333, Blast_Score=152, Evalue=3e-37,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=73.6526946107784, Blast_Score=509, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=32.2188449848024, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71995670, Length=325, Percent_Identity=32.6153846153846, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320099, Length=368, Percent_Identity=33.1521739130435, Blast_Score=174, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6322891, Length=350, Percent_Identity=28, Blast_Score=116, Evalue=4e-27,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=33.8235294117647, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI21357207, Length=327, Percent_Identity=30.2752293577982, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36045; Mature: 36045

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGIAVYDDKKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
QALADAGMTIEDIDGIAYTKGPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCEECCH
LEDDVPEFPFLALLVSGGHSMIVGVEGIGRYTVLGESVDDAAGEAFDKTAKLMGLDYPGG
HHCCCCCCCHHHHHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
PRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
CCHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHHHHEEHHHH
EAVVDTLAIKCKRALKQTGYKNLVIAGGVSANTRLRSSLAEMMQGLGGKVYYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCEECC
NGAMIAYAGLQRLKAGQVEGLEVKGQPRWPLDTLEPVD
CCCEEEEHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLGIETSCDETGIAVYDDKKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
QALADAGMTIEDIDGIAYTKGPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCEECCH
LEDDVPEFPFLALLVSGGHSMIVGVEGIGRYTVLGESVDDAAGEAFDKTAKLMGLDYPGG
HHCCCCCCCHHHHHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
PRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
CCHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHHHHEEHHHH
EAVVDTLAIKCKRALKQTGYKNLVIAGGVSANTRLRSSLAEMMQGLGGKVYYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCEECC
NGAMIAYAGLQRLKAGQVEGLEVKGQPRWPLDTLEPVD
CCCEEEEHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA