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The map label for this gene is ygjG [C]

Identifier: 157960764

GI number: 157960764

Start: 1142961

End: 1144301

Strand: Reverse

Name: ygjG [C]

Synonym: Spea_0936

Alternate gene names: 157960764

Gene position: 1144301-1142961 (Counterclockwise)

Preceding gene: 157960770

Following gene: 157960763

Centisome position: 22.11

GC content: 49.74

Gene sequence:

>1341_bases
ATGGCAGATCCACAGATGCACAATCAAAGCGATGCGCAATCATTAGAACATTACTGGATGCCGTTTACGGCAAATAGGCA
GTTTAAGTCGAGCCCGAGAATGCTCGCCCATGCCGAAGGTATGTACTATAAAGATGTCGCAGGTCGCCCCATATTAGACG
GTACAGCAGGTTTGTGGTGCTGTAACGCCGGACACGGACGTAAAGAGATCTCTGAAGCGGTCAGCAAACAGATCCACGAA
ATGGACTACGCGCCCTCTTTTCAGATGGGTCATCCTTTAGCCTTTGAGCTAGCCGAGCGTTTAGCCCAAATCAGTCCTAA
AGGGCTAAATAAAGCCTTCTTCACTAATTCAGGTTCAGAATCTGTCGACAGCGCACTAAAAATCGCCCTTACCTATCACC
GCGCTAATGGTGAAGCGACTCGCACCCGTTTTATTGGTCGCGAACTGGGTTATCACGGTGTTGGCTTTGGCGGCATTTCT
GTTGGTGGTATCGGTAATAACCGTAAGACCTTTAACCAGCAGTTGCTACAAGGTGTTGACCACCTCCCCCATACATTAGA
CATGAAAGGCAATGCCTTTTGTCGCGGCATGCCAAAAACAGGCGCCGAGAAAGCCGAAGTACTCGAGCAACTGGTTGCCC
TGCACGGCGCAGAAAACATCGCCGCCGTAATAGTCGAGCCGATGTCTGGCTCGGCAGGGGTTATCTTGCCGCCAGAAGGC
TACCTGCAAAAGCTTCGCGAGATCACCAAAAAGCACGGCATCCTACTTATTTTTGATGAAGTGATTACAGCATTTGGTCG
TGTTGGCGACGCCTTTGCCAGTCAGCGTTGGGGCGTAGTACCCGATATGATCACCACGGCAAAAGCACTCAATAATGGCG
CAATCCCAATGGGCGCAGTACTGGTTGACGATAATATCTATGATACCTGTATGCAGGGGCCTGAAAACGCTATCGAGCTG
TTTCATGGCTACACCTATTCCGGCCACCCAGTAGCCGCAGCGGCAGCACTTGCCACTCTCAATATCTATGAAAATGAAAA
GCTGTTCGATCGTACTAAAGAGCTTGAAGGCTACTTCGAAGATGCAGTACACAGCCTAAAAGGCTTACCGAACGTGATTG
ATATTCGCAACACAGGCCTTGTTGGCGGCATTCAATTTGCTCCTAGCGAAAAGGGCGTGGGTAAGCGCGGCTTCGGGATA
TTCGAGCACTGTTTCGAAGCTGGCACCTTAGTGCGTGCTACCGGTGACATTATCGCGATTTCACCACCGTTAATTGTCGA
CAAACAGCAAATAGATCAGATCGTTAATACCCTTAGCGATGCGATTAAAGCTGTCGGTTAA

Upstream 100 bases:

>100_bases
TTCATGTTCATTATTTCTGACATAGCATGGAATATATCGACCGCTTGCCTAAAAAAGCAACAGATAAAAACAATAATTAA
ACTGAATCAAGGTAGATGAT

Downstream 100 bases:

>100_bases
TCTCTGTACCCATTGCATTTCCACCCGAGATAGCAGCGTTAATGCAATGGGCAAAACCATTACTTATAAACACAATTTGC
TCCCTTTGGGGAGTGATCAT

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MADPQMHNQSDAQSLEHYWMPFTANRQFKSSPRMLAHAEGMYYKDVAGRPILDGTAGLWCCNAGHGRKEISEAVSKQIHE
MDYAPSFQMGHPLAFELAERLAQISPKGLNKAFFTNSGSESVDSALKIALTYHRANGEATRTRFIGRELGYHGVGFGGIS
VGGIGNNRKTFNQQLLQGVDHLPHTLDMKGNAFCRGMPKTGAEKAEVLEQLVALHGAENIAAVIVEPMSGSAGVILPPEG
YLQKLREITKKHGILLIFDEVITAFGRVGDAFASQRWGVVPDMITTAKALNNGAIPMGAVLVDDNIYDTCMQGPENAIEL
FHGYTYSGHPVAAAAALATLNIYENEKLFDRTKELEGYFEDAVHSLKGLPNVIDIRNTGLVGGIQFAPSEKGVGKRGFGI
FEHCFEAGTLVRATGDIIAISPPLIVDKQQIDQIVNTLSDAIKAVG

Sequences:

>Translated_446_residues
MADPQMHNQSDAQSLEHYWMPFTANRQFKSSPRMLAHAEGMYYKDVAGRPILDGTAGLWCCNAGHGRKEISEAVSKQIHE
MDYAPSFQMGHPLAFELAERLAQISPKGLNKAFFTNSGSESVDSALKIALTYHRANGEATRTRFIGRELGYHGVGFGGIS
VGGIGNNRKTFNQQLLQGVDHLPHTLDMKGNAFCRGMPKTGAEKAEVLEQLVALHGAENIAAVIVEPMSGSAGVILPPEG
YLQKLREITKKHGILLIFDEVITAFGRVGDAFASQRWGVVPDMITTAKALNNGAIPMGAVLVDDNIYDTCMQGPENAIEL
FHGYTYSGHPVAAAAALATLNIYENEKLFDRTKELEGYFEDAVHSLKGLPNVIDIRNTGLVGGIQFAPSEKGVGKRGFGI
FEHCFEAGTLVRATGDIIAISPPLIVDKQQIDQIVNTLSDAIKAVG
>Mature_445_residues
ADPQMHNQSDAQSLEHYWMPFTANRQFKSSPRMLAHAEGMYYKDVAGRPILDGTAGLWCCNAGHGRKEISEAVSKQIHEM
DYAPSFQMGHPLAFELAERLAQISPKGLNKAFFTNSGSESVDSALKIALTYHRANGEATRTRFIGRELGYHGVGFGGISV
GGIGNNRKTFNQQLLQGVDHLPHTLDMKGNAFCRGMPKTGAEKAEVLEQLVALHGAENIAAVIVEPMSGSAGVILPPEGY
LQKLREITKKHGILLIFDEVITAFGRVGDAFASQRWGVVPDMITTAKALNNGAIPMGAVLVDDNIYDTCMQGPENAIELF
HGYTYSGHPVAAAAALATLNIYENEKLFDRTKELEGYFEDAVHSLKGLPNVIDIRNTGLVGGIQFAPSEKGVGKRGFGIF
EHCFEAGTLVRATGDIIAISPPLIVDKQQIDQIVNTLSDAIKAVG

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=429, Percent_Identity=26.5734265734266, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI37574042, Length=458, Percent_Identity=27.5109170305677, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI226442705, Length=458, Percent_Identity=27.7292576419214, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI13994255, Length=440, Percent_Identity=27.2727272727273, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI226442709, Length=399, Percent_Identity=28.8220551378446, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI284507298, Length=230, Percent_Identity=32.1739130434783, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI24119277, Length=446, Percent_Identity=25.3363228699552, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI145693181, Length=406, Percent_Identity=31.7733990147783, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1786991, Length=433, Percent_Identity=30.4849884526559, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788044, Length=418, Percent_Identity=26.555023923445, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789759, Length=409, Percent_Identity=28.6063569682152, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1787560, Length=434, Percent_Identity=26.7281105990783, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789016, Length=423, Percent_Identity=25.7683215130024, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786349, Length=379, Percent_Identity=28.2321899736148, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=29.3181818181818, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI25144271, Length=432, Percent_Identity=28.7037037037037, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=266, Percent_Identity=34.2105263157895, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71992977, Length=438, Percent_Identity=26.027397260274, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17541228, Length=107, Percent_Identity=39.2523364485981, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323470, Length=440, Percent_Identity=26.5909090909091, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324386, Length=469, Percent_Identity=24.5202558635394, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324432, Length=414, Percent_Identity=24.1545893719807, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI161085790, Length=465, Percent_Identity=27.3118279569892, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21357415, Length=418, Percent_Identity=26.555023923445, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28574759, Length=464, Percent_Identity=27.3706896551724, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=27.1264367816092, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48279; Mature: 48147

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPQMHNQSDAQSLEHYWMPFTANRQFKSSPRMLAHAEGMYYKDVAGRPILDGTAGLWC
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEECCCCCCCCCCCCCCEEE
CNAGHGRKEISEAVSKQIHEMDYAPSFQMGHPLAFELAERLAQISPKGLNKAFFTNSGSE
ECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHEECCCCCH
SVDSALKIALTYHRANGEATRTRFIGRELGYHGVGFGGISVGGIGNNRKTFNQQLLQGVD
HHHHHHEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
HLPHTLDMKGNAFCRGMPKTGAEKAEVLEQLVALHGAENIAAVIVEPMSGSAGVILPPEG
HCCCEECCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHH
YLQKLREITKKHGILLIFDEVITAFGRVGDAFASQRWGVVPDMITTAKALNNGAIPMGAV
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEE
LVDDNIYDTCMQGPENAIELFHGYTYSGHPVAAAAALATLNIYENEKLFDRTKELEGYFE
EECCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DAVHSLKGLPNVIDIRNTGLVGGIQFAPSEKGVGKRGFGIFEHCFEAGTLVRATGDIIAI
HHHHHHHCCCCEEEECCCCCEECEEECCCCCCCCCCCCHHHHHHHHCCCEEEECCCEEEE
SPPLIVDKQQIDQIVNTLSDAIKAVG
CCCCEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADPQMHNQSDAQSLEHYWMPFTANRQFKSSPRMLAHAEGMYYKDVAGRPILDGTAGLWC
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEECCCCCCCCCCCCCCEEE
CNAGHGRKEISEAVSKQIHEMDYAPSFQMGHPLAFELAERLAQISPKGLNKAFFTNSGSE
ECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHEECCCCCH
SVDSALKIALTYHRANGEATRTRFIGRELGYHGVGFGGISVGGIGNNRKTFNQQLLQGVD
HHHHHHEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
HLPHTLDMKGNAFCRGMPKTGAEKAEVLEQLVALHGAENIAAVIVEPMSGSAGVILPPEG
HCCCEECCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHH
YLQKLREITKKHGILLIFDEVITAFGRVGDAFASQRWGVVPDMITTAKALNNGAIPMGAV
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEE
LVDDNIYDTCMQGPENAIELFHGYTYSGHPVAAAAALATLNIYENEKLFDRTKELEGYFE
EECCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DAVHSLKGLPNVIDIRNTGLVGGIQFAPSEKGVGKRGFGIFEHCFEAGTLVRATGDIIAI
HHHHHHHCCCCEEEECCCCCEECEEECCCCCCCCCCCCHHHHHHHHCCCEEEECCCEEEE
SPPLIVDKQQIDQIVNTLSDAIKAVG
CCCCEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]