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The map label for this gene is trpS [H]

Identifier: 157825842

GI number: 157825842

Start: 699481

End: 700473

Strand: Direct

Name: trpS [H]

Synonym: A1C_03905

Alternate gene names: 157825842

Gene position: 699481-700473 (Clockwise)

Preceding gene: 157825839

Following gene: 157825843

Centisome position: 56.82

GC content: 32.73

Gene sequence:

>993_bases
ATGAAAAAAACTGTTCTTTCCGGTGTGCAAGCGACCGGTTCTTTACATCTCGGTAACTATTTAGGTTCAATTAGACACTG
GGTTAAAATGCAGGAAGAATATAATTGTTTTTTCTTCTTAGCAGATTTGCATTCTATCACGGTTGATATTAAGCCATCAG
AACTTAATAATTCAATTATAGGGGTTCTTGCTGTTTATTTAGCAGCAGGGCTTAACCCTGATAAAGTAACGATTTTTGCC
CAAAGTATGGTGAAAGAGCATGCAGAGTTTGCTTGGCTACTAAACTGTGTTACACCTCTTGGATGGTTAAAGCGAATGAC
GCAATTTAAAGATAAAGCAGGAAGCGATCAGGAAAAAGCTTACCTTGGGTTATTTTCTTATCCGGTACTTATGGCAGCGG
ATATATTGATATATAAAGCTGATATAGTGCCTGTAGGTGAGGATCAGAAGCAGCATTTAGAGCTCACAAGAGATATTGCA
GGTGTGATAAATAGAAAATTTGATAAAGAAATTCTAAAAGTACCTGAACCATTAATTAGTGGTTCAGGTACAAGAATCAT
GAGCTTACGGGATGGATTAAATAAAATGAGTAAATCTGATATATCTGATTTCGCGCGTATTAATTTGAAAGATGATAATG
ACCTTATTCATCAAAAAATAAAAAAAGCCAAAACTGATCATTTAAGCTTTGTGAGCTATGATAAAGAAACAAGACCGGAA
ATTAGTAATTTATTAGATATTTATAGAAGTTTATCCGAAGAGAGTTTAGAAAAAATAATAAATAATTATCAGAACCAAGG
TTTTACGAAATTTAAAGAAGATTTAGCAGAAATTATTATTACAAATCTACAACCGATACGTGATAAATATTTAGAATTAA
TGAATGATAAAGAATATTTATTAAAAATACTACGCAGTGGCGCAGAAAAAGCAAGCATTAGAGCTTCTGAAACGGTTAAC
GCAGTGAAAGAACAATTTGGATTTGTGATTTAA

Upstream 100 bases:

>100_bases
TAAAATTCTTAAACGCCACAGCATAATTATTAAATAATTATTAATTAAAATAGTACTTATAACATAAATTTATAGCGAGT
AAAATAAATAAGGTATTATA

Downstream 100 bases:

>100_bases
ATTTATAATTTAAAGATTTCCCTTGAAATATATAAGATTATTTGGTATGAATCTTCTCGGATAGGTGGCCGAGTGGTTTA
AGGCACTAGTCTTGAAAACT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKKTVLSGVQATGSLHLGNYLGSIRHWVKMQEEYNCFFFLADLHSITVDIKPSELNNSIIGVLAVYLAAGLNPDKVTIFA
QSMVKEHAEFAWLLNCVTPLGWLKRMTQFKDKAGSDQEKAYLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIA
GVINRKFDKEILKVPEPLISGSGTRIMSLRDGLNKMSKSDISDFARINLKDDNDLIHQKIKKAKTDHLSFVSYDKETRPE
ISNLLDIYRSLSEESLEKIINNYQNQGFTKFKEDLAEIIITNLQPIRDKYLELMNDKEYLLKILRSGAEKASIRASETVN
AVKEQFGFVI

Sequences:

>Translated_330_residues
MKKTVLSGVQATGSLHLGNYLGSIRHWVKMQEEYNCFFFLADLHSITVDIKPSELNNSIIGVLAVYLAAGLNPDKVTIFA
QSMVKEHAEFAWLLNCVTPLGWLKRMTQFKDKAGSDQEKAYLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIA
GVINRKFDKEILKVPEPLISGSGTRIMSLRDGLNKMSKSDISDFARINLKDDNDLIHQKIKKAKTDHLSFVSYDKETRPE
ISNLLDIYRSLSEESLEKIINNYQNQGFTKFKEDLAEIIITNLQPIRDKYLELMNDKEYLLKILRSGAEKASIRASETVN
AVKEQFGFVI
>Mature_330_residues
MKKTVLSGVQATGSLHLGNYLGSIRHWVKMQEEYNCFFFLADLHSITVDIKPSELNNSIIGVLAVYLAAGLNPDKVTIFA
QSMVKEHAEFAWLLNCVTPLGWLKRMTQFKDKAGSDQEKAYLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIA
GVINRKFDKEILKVPEPLISGSGTRIMSLRDGLNKMSKSDISDFARINLKDDNDLIHQKIKKAKTDHLSFVSYDKETRPE
ISNLLDIYRSLSEESLEKIINNYQNQGFTKFKEDLAEIIITNLQPIRDKYLELMNDKEYLLKILRSGAEKASIRASETVN
AVKEQFGFVI

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=41.0334346504559, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI41352700, Length=180, Percent_Identity=48.8888888888889, Blast_Score=182, Evalue=4e-46,
Organism=Escherichia coli, GI1789786, Length=330, Percent_Identity=45.4545454545455, Blast_Score=296, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI71982800, Length=330, Percent_Identity=36.0606060606061, Blast_Score=202, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71982793, Length=330, Percent_Identity=36.0606060606061, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6320474, Length=350, Percent_Identity=37.4285714285714, Blast_Score=216, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24666151, Length=328, Percent_Identity=41.1585365853659, Blast_Score=256, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37453; Mature: 37453

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVLSGVQATGSLHLGNYLGSIRHWVKMQEEYNCFFFLADLHSITVDIKPSELNNSII
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHEEEEEECHHHHCHHHH
GVLAVYLAAGLNPDKVTIFAQSMVKEHAEFAWLLNCVTPLGWLKRMTQFKDKAGSDQEKA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIAGVINRKFDKEILKVPEPLIS
HHHHHHHHHHHHHHHHHEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
GSGTRIMSLRDGLNKMSKSDISDFARINLKDDNDLIHQKIKKAKTDHLSFVSYDKETRPE
CCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ISNLLDIYRSLSEESLEKIINNYQNQGFTKFKEDLAEIIITNLQPIRDKYLELMNDKEYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LKILRSGAEKASIRASETVNAVKEQFGFVI
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKTVLSGVQATGSLHLGNYLGSIRHWVKMQEEYNCFFFLADLHSITVDIKPSELNNSII
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHEEEEEECHHHHCHHHH
GVLAVYLAAGLNPDKVTIFAQSMVKEHAEFAWLLNCVTPLGWLKRMTQFKDKAGSDQEKA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIAGVINRKFDKEILKVPEPLIS
HHHHHHHHHHHHHHHHHEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
GSGTRIMSLRDGLNKMSKSDISDFARINLKDDNDLIHQKIKKAKTDHLSFVSYDKETRPE
CCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ISNLLDIYRSLSEESLEKIINNYQNQGFTKFKEDLAEIIITNLQPIRDKYLELMNDKEYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LKILRSGAEKASIRASETVNAVKEQFGFVI
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]