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The map label for this gene is ctaD [H]

Identifier: 157825681

GI number: 157825681

Start: 546881

End: 548503

Strand: Reverse

Name: ctaD [H]

Synonym: A1C_03015

Alternate gene names: 157825681

Gene position: 548503-546881 (Counterclockwise)

Preceding gene: 157825682

Following gene: 157825680

Centisome position: 44.56

GC content: 40.67

Gene sequence:

>1623_bases
ATGAAAACAGGCAAAATAATAATTATGGATATAACTACTACCGAAATTTATCACGATGACCAGCACATCCCGAACGGTTG
GAGGCGATGGCTTTTTTCTACCAATCACAAAGATATCAGCATTATGTATATCATATTTGCCGTTTTTGCCGGAATTGTCG
GAGGGTTATTTTCTCTTCTATTTAGGTTAGAGCTTGCAATGCCCGGCGGCACTTTCTTAAATCATGATTTCCAGCTATAT
AACGTGCTTATCACAGCACATGCGGTTATTATGGTATTCTTTATGATTATGCCGGCGTTGTTTGGTGGTTTTGGTAACTA
TTTCGTACCTCTATTAATAGGGGCTCCCGATATGGCATTTCCACGCCTTAACAATATCAGTTTTTGGCTACTAATTCCTG
CTTTTTTCTTACTTATTGGTTCGGCTTTTGTTGACGGCGGACCGGGAACGGGCTGGACGCTCTACCCTCCTTTAAGTAAT
TTGAGCGGTCACCCGGGGGCAGCAGTTGATATGGCTATTTTCAGCTTACATTTAACAGGTCTATCGTCAATCCTCGGATC
AATTAACTTAATTGTTACTATCTTTAATATGAGAGCTCCAGGGATGGGTCTTTTCAAGATGCCTTTATTTGTTTGGTCTA
TCTTAGTAACTGCATTTCTGATAATCTTAGCTATGCCGGTGCTTGGCGGGGCTGTCACTATGCTCCTTACTGATCGTAAC
TTTGGTACCACTTTCTTTAAGCCTGATGGCGGCGGTGATCCTGTATTATTTCAGCATCTATTTTGGTTTTTCGGTCATCC
TGAAGTATATATCGTAATACTTCCAGGCTTTGGTATAGTAAGTCATGTTATTTCAACTTTTTCACGCAAACCTATATTTG
GTTATCAAGGTATGGTCGGAGCTATGGTAATAATCGGTTTCGTCGGATTTATCGTATGGGCTCACCATATGTTTACTGTT
GGGCTTTCTTATAATACACTTATATATTTCACTGCCGGAACGATGATTATAGCAGTTCCGACAGGCGTTAAAATATTTAG
CTGGATAGCGACTATGTGGGGCGGTTCTATTACATTCCCAACTCCTATGTTATTTTCGATAGGATTTATTATATTATTCA
CGATTGGCGGCGTAACTGGTATAATCCTATCAAATTCGGCACTTGATCGAGTTCTGCACGATACATATTATGTTGTTGCA
CATTTCCATTATACGATGTCACTCGGTGCTTTATTTACGGCATTTGCAGGCTTTTATTATTGGTTTGGAAAAATATCCGG
TAAACAATATCCAGAAATTTTAGGCAAAATCCATTTTTGGATTACATTTATTGGGGTTAATTTAACTTTCTTCCCGCAGC
ATTTCTTAGGTCTTGCGGGCATGCCAAGAAGAATACCGGATTACCCTGAAGCTTTCGGCGGCTGGAATATGGTTTCATCG
ATAGGAGCAGGTATCTCTATGGTGGCGGCTCTTTATTTTGTATTTATCGTTTTCTATACGCTAAAATATGGCAAAAATTG
TCCGGCCAATCCGTGGGGTGACGGTGCTAATACGCTTGAGTGGACGCTTACCTCACCACCGCCGTTCCATACTTTTGAAA
CACCACCGCATATTGAGGGGTAA

Upstream 100 bases:

>100_bases
GAAAGGCCTGGATTCCTACTTTTGCATGAATGACATATAGCACTTTTTTAGAACCAAAAAACAATGACATAATTGCATAC
CAGAACAAACAAAGTGAAAA

Downstream 100 bases:

>100_bases
TAGTGGCTTTAGTGGATGCCAAATCGTCATTGTGAGAAATTGCGTTAGCAACAAGAAGCGGCGATCTCAAGAGTTTGTTA
TTATTTCACGAGATTGCCAC

Product: cytochrome c oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MKTGKIIIMDITTTEIYHDDQHIPNGWRRWLFSTNHKDISIMYIIFAVFAGIVGGLFSLLFRLELAMPGGTFLNHDFQLY
NVLITAHAVIMVFFMIMPALFGGFGNYFVPLLIGAPDMAFPRLNNISFWLLIPAFFLLIGSAFVDGGPGTGWTLYPPLSN
LSGHPGAAVDMAIFSLHLTGLSSILGSINLIVTIFNMRAPGMGLFKMPLFVWSILVTAFLIILAMPVLGGAVTMLLTDRN
FGTTFFKPDGGGDPVLFQHLFWFFGHPEVYIVILPGFGIVSHVISTFSRKPIFGYQGMVGAMVIIGFVGFIVWAHHMFTV
GLSYNTLIYFTAGTMIIAVPTGVKIFSWIATMWGGSITFPTPMLFSIGFIILFTIGGVTGIILSNSALDRVLHDTYYVVA
HFHYTMSLGALFTAFAGFYYWFGKISGKQYPEILGKIHFWITFIGVNLTFFPQHFLGLAGMPRRIPDYPEAFGGWNMVSS
IGAGISMVAALYFVFIVFYTLKYGKNCPANPWGDGANTLEWTLTSPPPFHTFETPPHIEG

Sequences:

>Translated_540_residues
MKTGKIIIMDITTTEIYHDDQHIPNGWRRWLFSTNHKDISIMYIIFAVFAGIVGGLFSLLFRLELAMPGGTFLNHDFQLY
NVLITAHAVIMVFFMIMPALFGGFGNYFVPLLIGAPDMAFPRLNNISFWLLIPAFFLLIGSAFVDGGPGTGWTLYPPLSN
LSGHPGAAVDMAIFSLHLTGLSSILGSINLIVTIFNMRAPGMGLFKMPLFVWSILVTAFLIILAMPVLGGAVTMLLTDRN
FGTTFFKPDGGGDPVLFQHLFWFFGHPEVYIVILPGFGIVSHVISTFSRKPIFGYQGMVGAMVIIGFVGFIVWAHHMFTV
GLSYNTLIYFTAGTMIIAVPTGVKIFSWIATMWGGSITFPTPMLFSIGFIILFTIGGVTGIILSNSALDRVLHDTYYVVA
HFHYTMSLGALFTAFAGFYYWFGKISGKQYPEILGKIHFWITFIGVNLTFFPQHFLGLAGMPRRIPDYPEAFGGWNMVSS
IGAGISMVAALYFVFIVFYTLKYGKNCPANPWGDGANTLEWTLTSPPPFHTFETPPHIEG
>Mature_540_residues
MKTGKIIIMDITTTEIYHDDQHIPNGWRRWLFSTNHKDISIMYIIFAVFAGIVGGLFSLLFRLELAMPGGTFLNHDFQLY
NVLITAHAVIMVFFMIMPALFGGFGNYFVPLLIGAPDMAFPRLNNISFWLLIPAFFLLIGSAFVDGGPGTGWTLYPPLSN
LSGHPGAAVDMAIFSLHLTGLSSILGSINLIVTIFNMRAPGMGLFKMPLFVWSILVTAFLIILAMPVLGGAVTMLLTDRN
FGTTFFKPDGGGDPVLFQHLFWFFGHPEVYIVILPGFGIVSHVISTFSRKPIFGYQGMVGAMVIIGFVGFIVWAHHMFTV
GLSYNTLIYFTAGTMIIAVPTGVKIFSWIATMWGGSITFPTPMLFSIGFIILFTIGGVTGIILSNSALDRVLHDTYYVVA
HFHYTMSLGALFTAFAGFYYWFGKISGKQYPEILGKIHFWITFIGVNLTFFPQHFLGLAGMPRRIPDYPEAFGGWNMVSS
IGAGISMVAALYFVFIVFYTLKYGKNCPANPWGDGANTLEWTLTSPPPFHTFETPPHIEG

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=58.2846003898635, Blast_Score=582, Evalue=1e-166,
Organism=Escherichia coli, GI1786634, Length=521, Percent_Identity=42.6103646833013, Blast_Score=387, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6226519, Length=528, Percent_Identity=56.25, Blast_Score=607, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=60.5590062111801, Blast_Score=416, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=55.0607287449393, Blast_Score=278, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6226521, Length=66, Percent_Identity=51.5151515151515, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6226522, Length=79, Percent_Identity=48.1012658227848, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6226520, Length=54, Percent_Identity=50, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59751; Mature: 59751

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGKIIIMDITTTEIYHDDQHIPNGWRRWLFSTNHKDISIMYIIFAVFAGIVGGLFSLL
CCCCCEEEEEEEEHEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FRLELAMPGGTFLNHDFQLYNVLITAHAVIMVFFMIMPALFGGFGNYFVPLLIGAPDMAF
HHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCC
PRLNNISFWLLIPAFFLLIGSAFVDGGPGTGWTLYPPLSNLSGHPGAAVDMAIFSLHLTG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHH
LSSILGSINLIVTIFNMRAPGMGLFKMPLFVWSILVTAFLIILAMPVLGGAVTMLLTDRN
HHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
FGTTFFKPDGGGDPVLFQHLFWFFGHPEVYIVILPGFGIVSHVISTFSRKPIFGYQGMVG
CCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCHHHH
AMVIIGFVGFIVWAHHMFTVGLSYNTLIYFTAGTMIIAVPTGVKIFSWIATMWGGSITFP
HHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECEEEEEECCCHHHHHHHHHHHCCCCCCC
TPMLFSIGFIILFTIGGVTGIILSNSALDRVLHDTYYVVAHFHYTMSLGALFTAFAGFYY
CHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHH
WFGKISGKQYPEILGKIHFWITFIGVNLTFFPQHFLGLAGMPRRIPDYPEAFGGWNMVSS
HHHHCCCCHHHHHHHHHHHHHEEEECCEEECHHHHHCCCCCCCCCCCCCHHCCCHHHHHH
IGAGISMVAALYFVFIVFYTLKYGKNCPANPWGDGANTLEWTLTSPPPFHTFETPPHIEG
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTGKIIIMDITTTEIYHDDQHIPNGWRRWLFSTNHKDISIMYIIFAVFAGIVGGLFSLL
CCCCCEEEEEEEEHEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FRLELAMPGGTFLNHDFQLYNVLITAHAVIMVFFMIMPALFGGFGNYFVPLLIGAPDMAF
HHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCC
PRLNNISFWLLIPAFFLLIGSAFVDGGPGTGWTLYPPLSNLSGHPGAAVDMAIFSLHLTG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHH
LSSILGSINLIVTIFNMRAPGMGLFKMPLFVWSILVTAFLIILAMPVLGGAVTMLLTDRN
HHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
FGTTFFKPDGGGDPVLFQHLFWFFGHPEVYIVILPGFGIVSHVISTFSRKPIFGYQGMVG
CCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCHHHH
AMVIIGFVGFIVWAHHMFTVGLSYNTLIYFTAGTMIIAVPTGVKIFSWIATMWGGSITFP
HHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECEEEEEECCCHHHHHHHHHHHCCCCCCC
TPMLFSIGFIILFTIGGVTGIILSNSALDRVLHDTYYVVAHFHYTMSLGALFTAFAGFYY
CHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHH
WFGKISGKQYPEILGKIHFWITFIGVNLTFFPQHFLGLAGMPRRIPDYPEAFGGWNMVSS
HHHHCCCCHHHHHHHHHHHHHEEEECCEEECHHHHHCCCCCCCCCCCCCHHCCCHHHHHH
IGAGISMVAALYFVFIVFYTLKYGKNCPANPWGDGANTLEWTLTSPPPFHTFETPPHIEG
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]