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The map label for this gene is ruvA

Identifier: 157825657

GI number: 157825657

Start: 523128

End: 523739

Strand: Direct

Name: ruvA

Synonym: A1C_02895

Alternate gene names: 157825657

Gene position: 523128-523739 (Clockwise)

Preceding gene: 157825656

Following gene: 157825658

Centisome position: 42.49

GC content: 34.31

Gene sequence:

>612_bases
ATGATCGGTAAATTAAGTGGTAAGATTGATGCCCAAGGTGATGATTACATTATAATTGACGTAAATGGGGTAGGATACTT
AGTCTATGCTTCGGGTAAAACTTTAGGTAAACTTTCAGAAGGGGAATTTTATAAACTATTTATCGAAACCCATGTTAGAG
AGGAACATATTCATCTTTACGGTTTTCTAACTATAGAAGAGAAGAATTTTTTTAATTTGCTGCAATCCGTGAACGGTATT
GGTACGAGAATGGCTCTATCTATTTTATCAAATCTAACTCCTACGGATATTCAAATTGCTATAAATAATGAAGATAAAGA
TATATTTAAAGCAATATCTGGCGTCGGTGCTAAACTTGCTGAGCGTATAGTTCTAGAGCTGAAAGGTAAAGTAGCGAAAA
TATCAACTGGTGCGGCTATTATCAACGATAGCTTAAATATCAAAAATATTACATCGGTCGCAAGCAATGAAGTAATAAAA
GCTCTAGTAAATCTAGGCTTTTCTAGATTTGAAGCTCAAAACTCCGTTCAAGGCATTGTTATCCAAAACCCTGAAATCTC
TATTGATGAATTAATCAAAACAGCCCTGAAAAATCGCAATGCTGGCCTTTAA

Upstream 100 bases:

>100_bases
GACCGCTTGTTATTCATTACATCTTAGCAGCAATTATTACCGCTTTACCGGCACTAATTTTAATATATAGTAGAAGTAAG
AAAAAGAAGAAATAAATTAT

Downstream 100 bases:

>100_bases
ATCAAATGTTAATTTATTAATACTTGATTCAAAAGAAATATCATTAAAATTAATAGGTAGAATTATGTCAAAATTAAAAA
TATTTTTAGCAAGTATTAAT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MIGKLSGKIDAQGDDYIIIDVNGVGYLVYASGKTLGKLSEGEFYKLFIETHVREEHIHLYGFLTIEEKNFFNLLQSVNGI
GTRMALSILSNLTPTDIQIAINNEDKDIFKAISGVGAKLAERIVLELKGKVAKISTGAAIINDSLNIKNITSVASNEVIK
ALVNLGFSRFEAQNSVQGIVIQNPEISIDELIKTALKNRNAGL

Sequences:

>Translated_203_residues
MIGKLSGKIDAQGDDYIIIDVNGVGYLVYASGKTLGKLSEGEFYKLFIETHVREEHIHLYGFLTIEEKNFFNLLQSVNGI
GTRMALSILSNLTPTDIQIAINNEDKDIFKAISGVGAKLAERIVLELKGKVAKISTGAAIINDSLNIKNITSVASNEVIK
ALVNLGFSRFEAQNSVQGIVIQNPEISIDELIKTALKNRNAGL
>Mature_203_residues
MIGKLSGKIDAQGDDYIIIDVNGVGYLVYASGKTLGKLSEGEFYKLFIETHVREEHIHLYGFLTIEEKNFFNLLQSVNGI
GTRMALSILSNLTPTDIQIAINNEDKDIFKAISGVGAKLAERIVLELKGKVAKISTGAAIINDSLNIKNITSVASNEVIK
ALVNLGFSRFEAQNSVQGIVIQNPEISIDELIKTALKNRNAGL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=202, Percent_Identity=32.6732673267327, Blast_Score=94, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_RICAH (A8GN94)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493377.1
- ProteinModelPortal:   A8GN94
- SMR:   A8GN94
- STRING:   A8GN94
- GeneID:   5645777
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_02895
- NMPDR:   fig|293614.3.peg.538
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   YKTAMSI
- ProtClustDB:   PRK00116
- BioCyc:   RAKA293614:A1C_02895-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22092; Mature: 22092

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLSGKIDAQGDDYIIIDVNGVGYLVYASGKTLGKLSEGEFYKLFIETHVREEHIHLY
CCCCCCCEEECCCCCEEEEEECCCEEEEEECCCCCCCCCCCCEEEEEEEHHCCCCEEEEE
GFLTIEEKNFFNLLQSVNGIGTRMALSILSNLTPTDIQIAINNEDKDIFKAISGVGAKLA
EEEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
ERIVLELKGKVAKISTGAAIINDSLNIKNITSVASNEVIKALVNLGFSRFEAQNSVQGIV
HHHHHHHCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEE
IQNPEISIDELIKTALKNRNAGL
EECCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIGKLSGKIDAQGDDYIIIDVNGVGYLVYASGKTLGKLSEGEFYKLFIETHVREEHIHLY
CCCCCCCEEECCCCCEEEEEECCCEEEEEECCCCCCCCCCCCEEEEEEEHHCCCCEEEEE
GFLTIEEKNFFNLLQSVNGIGTRMALSILSNLTPTDIQIAINNEDKDIFKAISGVGAKLA
EEEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
ERIVLELKGKVAKISTGAAIINDSLNIKNITSVASNEVIKALVNLGFSRFEAQNSVQGIV
HHHHHHHCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEE
IQNPEISIDELIKTALKNRNAGL
EECCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA