Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 157825624

GI number: 157825624

Start: 486550

End: 487470

Strand: Direct

Name: xerD [H]

Synonym: A1C_02705

Alternate gene names: 157825624

Gene position: 486550-487470 (Clockwise)

Preceding gene: 157825623

Following gene: 157825625

Centisome position: 39.52

GC content: 33.12

Gene sequence:

>921_bases
ATGGAATTTATTTCGCAATTCCTAGAAATGCTCTTAGCCGAGCGAGCATTATCAAAAAATTCTATACTTAGCTATAAGCG
TGACCTATGCGATTTTCAAAACTATCTTGCTAAACAAAGATTATCCGCATTAAATATTACCACAGCAAATGTTAGAGATT
GGATTGAGTATCTAGCAAATAATGATTTACAAGCACGCTCAATCAACAGAAAAATCTCAACTGTAAAAAACTACTATGAA
TTTTTAATTAGCGAAAATCATACTACCTTTAATCCGGTTCTTAACGTAGATTTACCGAAATACCAAAATAAACTTCCTGA
AATACTGTCTATAGATCAGATTAAATCGCTACTTGAATATTGCTCGCAAGATAATTCTCCTGAAGGTATAAGGCTTAATG
CGATGATTCATTTGCTTTATGCTAGTGGCCTTAGAGTCTCGGAGCTTGTGAGTCTTAAACTTAGCGATATTCTGACTAAT
AAAACATCTAAAGGAGAAGTAAGAAAAATATTTTCGGTACTTGGTAAAGGTAATAAGGAAAGAGTCATAGTAATAAATGA
ACAGGCAGTTATCTCTATTGCCAAATATCTTGCAATTAGAGATATTTTTGTGAATAAAGCTAAACCAAAAAATCTAATTT
ATTTATTTCCCTCATCAGCTTTAACAGGTTATATGACTAGGCAAAATTTTGCAATTCTGTTAAAATCTGCTGCTCTTTAT
GCCAATCTTAACCCTGAACATGTTTCTCCTCATATATTACGCCACAGCTTTGCAAGTCATTTACTTGAGGGCGGAGCAGA
CTTAAGAGTAATTCAAGATCTACTCGGCCATTCTGATATATCAACGACCCAAATATATACTCATCTTCAAACTCATCATC
TAAAAAAAGCATTATTGCATCACCCTCTTAACACAAATTAA

Upstream 100 bases:

>100_bases
CCTAGGCTGGGTAGCAAAGTGGTAATGCCGTGGACTGCAAATCCTCTATTCGTCGGTTCGATTCCGACCCTGGCCTCCAT
TATAGAAATTAAAAAATCTT

Downstream 100 bases:

>100_bases
TTTATATTAATCTTTTATAAAGTTCTTGTTAATATTTTTTAACTAAATATAATACGTCTTGTTAATTTAAGGAATAAATT
ATATGAAGCTAAAAGAAATG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MEFISQFLEMLLAERALSKNSILSYKRDLCDFQNYLAKQRLSALNITTANVRDWIEYLANNDLQARSINRKISTVKNYYE
FLISENHTTFNPVLNVDLPKYQNKLPEILSIDQIKSLLEYCSQDNSPEGIRLNAMIHLLYASGLRVSELVSLKLSDILTN
KTSKGEVRKIFSVLGKGNKERVIVINEQAVISIAKYLAIRDIFVNKAKPKNLIYLFPSSALTGYMTRQNFAILLKSAALY
ANLNPEHVSPHILRHSFASHLLEGGADLRVIQDLLGHSDISTTQIYTHLQTHHLKKALLHHPLNTN

Sequences:

>Translated_306_residues
MEFISQFLEMLLAERALSKNSILSYKRDLCDFQNYLAKQRLSALNITTANVRDWIEYLANNDLQARSINRKISTVKNYYE
FLISENHTTFNPVLNVDLPKYQNKLPEILSIDQIKSLLEYCSQDNSPEGIRLNAMIHLLYASGLRVSELVSLKLSDILTN
KTSKGEVRKIFSVLGKGNKERVIVINEQAVISIAKYLAIRDIFVNKAKPKNLIYLFPSSALTGYMTRQNFAILLKSAALY
ANLNPEHVSPHILRHSFASHLLEGGADLRVIQDLLGHSDISTTQIYTHLQTHHLKKALLHHPLNTN
>Mature_306_residues
MEFISQFLEMLLAERALSKNSILSYKRDLCDFQNYLAKQRLSALNITTANVRDWIEYLANNDLQARSINRKISTVKNYYE
FLISENHTTFNPVLNVDLPKYQNKLPEILSIDQIKSLLEYCSQDNSPEGIRLNAMIHLLYASGLRVSELVSLKLSDILTN
KTSKGEVRKIFSVLGKGNKERVIVINEQAVISIAKYLAIRDIFVNKAKPKNLIYLFPSSALTGYMTRQNFAILLKSAALY
ANLNPEHVSPHILRHSFASHLLEGGADLRVIQDLLGHSDISTTQIYTHLQTHHLKKALLHHPLNTN

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=304, Percent_Identity=40.7894736842105, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=35.2739726027397, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34829; Mature: 34829

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFISQFLEMLLAERALSKNSILSYKRDLCDFQNYLAKQRLSALNITTANVRDWIEYLAN
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
NDLQARSINRKISTVKNYYEFLISENHTTFNPVLNVDLPKYQNKLPEILSIDQIKSLLEY
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCEEECCCCHHHHHCHHHHHHHHHHHHHHH
CSQDNSPEGIRLNAMIHLLYASGLRVSELVSLKLSDILTNKTSKGEVRKIFSVLGKGNKE
HCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
RVIVINEQAVISIAKYLAIRDIFVNKAKPKNLIYLFPSSALTGYMTRQNFAILLKSAALY
EEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ANLNPEHVSPHILRHSFASHLLEGGADLRVIQDLLGHSDISTTQIYTHLQTHHLKKALLH
CCCCHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
HPLNTN
CCCCCC
>Mature Secondary Structure
MEFISQFLEMLLAERALSKNSILSYKRDLCDFQNYLAKQRLSALNITTANVRDWIEYLAN
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
NDLQARSINRKISTVKNYYEFLISENHTTFNPVLNVDLPKYQNKLPEILSIDQIKSLLEY
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCEEECCCCHHHHHCHHHHHHHHHHHHHHH
CSQDNSPEGIRLNAMIHLLYASGLRVSELVSLKLSDILTNKTSKGEVRKIFSVLGKGNKE
HCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
RVIVINEQAVISIAKYLAIRDIFVNKAKPKNLIYLFPSSALTGYMTRQNFAILLKSAALY
EEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ANLNPEHVSPHILRHSFASHLLEGGADLRVIQDLLGHSDISTTQIYTHLQTHHLKKALLH
CCCCHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
HPLNTN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]