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The map label for this gene is ctaB

Identifier: 157825599

GI number: 157825599

Start: 467004

End: 467921

Strand: Direct

Name: ctaB

Synonym: A1C_02570

Alternate gene names: 157825599

Gene position: 467004-467921 (Clockwise)

Preceding gene: 157825592

Following gene: 157825602

Centisome position: 37.94

GC content: 33.12

Gene sequence:

>918_bases
ATGAGTTCTTTAGTAACGCAAATCGATTTAGATAAAATCAATCATTCACAAAGTACCGTTAAAGACTATATCTTACTTAT
GAAACCGCGTGTGATGTCGCTTGTAATGTTTACAGGTTTTGTAGGTATGTGGCTTGCTCCTTATTCTGTGCATCCTTTTA
TTGCTGTTATTGTGCTTGCTTGCATATCTCTTGGGGCAGGGAGTGCAGGGGCAATTAATATGTGGTACGATAGAGATATC
GATAGCTTAATGAAACGTACTCAAAAAAGACCTCTCGTCAGAGGTGCTATAGAACCTGATGAGGCTTTATCTTTTGGTTT
GATAACAGGATTTTTTGCAGTATTTTTTATGGCTTTATGTGTTAATTTACTTGCATCCTTTTTACTGCTATTCACTATTT
TTTACTATATCTGTATTTATACTATTTGGTTAAAGCGTCGTTCTATACAAAATATTGTTATTGGCGGAGTATCGGGAGCA
TTACCTCCTGTGATAGGTTATGCAGCGGTAAGTAATACTATATCTCTAGAGTCAATTATATTATTTTTAATTATTTTTAT
TTGGACACCGCCGCATTCATGGGCTCTCGCTTTATTCTGTAACGATGATTATAAAAACTGTAAAGTACCGATGATGCCTA
CAGTAAAAGGGATTTTATATACTAAGGAACAGATTCTAATTTACAGCATTCTTTTATTTCTTGTTTCGTTAATGCCGTTT
TTTATTGGAATGAATAATTTTATATATTTGATAATTGCCGGTATGCTTGGGTTAGTATTTCTATATTATTCCGGTTCTTT
ATTCTATGACACCCCTGATAACAAACAAGCTAAACGATTGTTTGCCTATTCGATATTTTATTTGTTTTTTATCTTTTTAC
TTTTGTCTTCAACTAGCACTATATCCAATATTAGCTAA

Upstream 100 bases:

>100_bases
TATATTTGAACTACGAGACAATGATATACATTTCTTATATCAAAGTCAATCATTGATTTTTACCTTAAAACTTTTTATAT
TTAATTAAAAAATATTTCAT

Downstream 100 bases:

>100_bases
GAGATAATAGTGTTGGGTTACTTTTATGGACGATAAAATTGAAACTCAACGTGAAGCAACATATCATAAGTTTATTTTCA
TGCAAGTGATTTTGTATTTA

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSSLVTQIDLDKINHSQSTVKDYILLMKPRVMSLVMFTGFVGMWLAPYSVHPFIAVIVLACISLGAGSAGAINMWYDRDI
DSLMKRTQKRPLVRGAIEPDEALSFGLITGFFAVFFMALCVNLLASFLLLFTIFYYICIYTIWLKRRSIQNIVIGGVSGA
LPPVIGYAAVSNTISLESIILFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPTVKGILYTKEQILIYSILLFLVSLMPF
FIGMNNFIYLIIAGMLGLVFLYYSGSLFYDTPDNKQAKRLFAYSIFYLFFIFLLLSSTSTISNIS

Sequences:

>Translated_305_residues
MSSLVTQIDLDKINHSQSTVKDYILLMKPRVMSLVMFTGFVGMWLAPYSVHPFIAVIVLACISLGAGSAGAINMWYDRDI
DSLMKRTQKRPLVRGAIEPDEALSFGLITGFFAVFFMALCVNLLASFLLLFTIFYYICIYTIWLKRRSIQNIVIGGVSGA
LPPVIGYAAVSNTISLESIILFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPTVKGILYTKEQILIYSILLFLVSLMPF
FIGMNNFIYLIIAGMLGLVFLYYSGSLFYDTPDNKQAKRLFAYSIFYLFFIFLLLSSTSTISNIS
>Mature_304_residues
SSLVTQIDLDKINHSQSTVKDYILLMKPRVMSLVMFTGFVGMWLAPYSVHPFIAVIVLACISLGAGSAGAINMWYDRDID
SLMKRTQKRPLVRGAIEPDEALSFGLITGFFAVFFMALCVNLLASFLLLFTIFYYICIYTIWLKRRSIQNIVIGGVSGAL
PPVIGYAAVSNTISLESIILFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPTVKGILYTKEQILIYSILLFLVSLMPFF
IGMNNFIYLIIAGMLGLVFLYYSGSLFYDTPDNKQAKRLFAYSIFYLFFIFLLLSSTSTISNIS

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily

Homologues:

Organism=Homo sapiens, GI17921982, Length=291, Percent_Identity=30.9278350515464, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1786631, Length=266, Percent_Identity=32.3308270676692, Blast_Score=138, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71998235, Length=272, Percent_Identity=28.6764705882353, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6325085, Length=262, Percent_Identity=31.2977099236641, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI19921064, Length=276, Percent_Identity=29.3478260869565, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXX_RICAH (A8GN36)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493319.1
- STRING:   A8GN36
- GeneID:   5645166
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_02570
- NMPDR:   fig|293614.3.peg.477
- eggNOG:   COG0109
- HOGENOM:   HBG656003
- OMA:   MALTEGW
- ProtClustDB:   PRK04375
- BioCyc:   RAKA293614:A1C_02570-MONOMER
- HAMAP:   MF_00154
- InterPro:   IPR006369
- InterPro:   IPR000537
- PANTHER:   PTHR11048:SF3
- TIGRFAMs:   TIGR01473

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 34413; Mature: 34281

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11c4fb20)-; HASH(0x11de483c)-; HASH(0x1237f7d0)-; HASH(0x403c6d74)-; HASH(0x12acc464)-; HASH(0x121e9be0)-; HASH(0x125e9a10)-; HASH(0x12337384)-; HASH(0x12413fac)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLVTQIDLDKINHSQSTVKDYILLMKPRVMSLVMFTGFVGMWLAPYSVHPFIAVIVLA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
CISLGAGSAGAINMWYDRDIDSLMKRTQKRPLVRGAIEPDEALSFGLITGFFAVFFMALC
HHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VNLLASFLLLFTIFYYICIYTIWLKRRSIQNIVIGGVSGALPPVIGYAAVSNTISLESII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCHHHHHHHH
LFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPTVKGILYTKEQILIYSILLFLVSLMPF
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGMNNFIYLIIAGMLGLVFLYYSGSLFYDTPDNKQAKRLFAYSIFYLFFIFLLLSSTST
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
ISNIS
HCCCH
>Mature Secondary Structure 
SSLVTQIDLDKINHSQSTVKDYILLMKPRVMSLVMFTGFVGMWLAPYSVHPFIAVIVLA
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
CISLGAGSAGAINMWYDRDIDSLMKRTQKRPLVRGAIEPDEALSFGLITGFFAVFFMALC
HHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VNLLASFLLLFTIFYYICIYTIWLKRRSIQNIVIGGVSGALPPVIGYAAVSNTISLESII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCHHHHHHHH
LFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPTVKGILYTKEQILIYSILLFLVSLMPF
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGMNNFIYLIIAGMLGLVFLYYSGSLFYDTPDNKQAKRLFAYSIFYLFFIFLLLSSTST
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
ISNIS
HCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA