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The map label for this gene is grxC [H]

Identifier: 157373049

GI number: 157373049

Start: 5335011

End: 5335259

Strand: Reverse

Name: grxC [H]

Synonym: Spro_4817

Alternate gene names: 157373049

Gene position: 5335259-5335011 (Counterclockwise)

Preceding gene: 157373050

Following gene: 157373048

Centisome position: 97.92

GC content: 50.2

Gene sequence:

>249_bases
ATGGCTAACATTGATATCTACACCAAAGCGACCTGTCCGTTCTGTCATCGCGCCAAAGCGTTGCTGAACAGCAAGGGAGC
CGCGTTTAACGAAATCGCCATTGATGGTGATAATGAAAAACGCGAAGCGATGATTGCGCGCAGTGGGCGCACCACCGTGC
CTCAGATTTTCATCGATGGCCAACATATTGGCGGCTGTGATGATTTATATGAACTCGATGCTCGTGGTGGTCTGGATCCG
CTGCTTTAA

Upstream 100 bases:

>100_bases
AATGTAGTTACGCTGAAAGACGGTATTGCCGGCTGGAGCGGGGAAAACCTGCCGTTAGTGCGCGGTAAGTAATTCTTTAA
CGTATTTGAGGTGGTAATCC

Downstream 100 bases:

>100_bases
GCGGATGACTGCCGGTTACTGAGTATCAATAAGGACGTTTAACCAAGGGTATTACACACATGTCAGAACAAAACAGCACA
GAGATGGCTTTCCAGATCCA

Product: glutaredoxin 3

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MANIDIYTKATCPFCHRAKALLNSKGAAFNEIAIDGDNEKREAMIARSGRTTVPQIFIDGQHIGGCDDLYELDARGGLDP
LL

Sequences:

>Translated_82_residues
MANIDIYTKATCPFCHRAKALLNSKGAAFNEIAIDGDNEKREAMIARSGRTTVPQIFIDGQHIGGCDDLYELDARGGLDP
LL
>Mature_81_residues
ANIDIYTKATCPFCHRAKALLNSKGAAFNEIAIDGDNEKREAMIARSGRTTVPQIFIDGQHIGGCDDLYELDARGGLDPL
L

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=82, Percent_Identity=79.2682926829268, Blast_Score=143, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 8909; Mature: 8778

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIDIYTKATCPFCHRAKALLNSKGAAFNEIAIDGDNEKREAMIARSGRTTVPQIFIDG
CCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHEEEECCCCCCCCEEEECC
QHIGGCDDLYELDARGGLDPLL
CCCCCCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
ANIDIYTKATCPFCHRAKALLNSKGAAFNEIAIDGDNEKREAMIARSGRTTVPQIFIDG
CCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHEEEECCCCCCCCEEEECC
QHIGGCDDLYELDARGGLDPLL
CCCCCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]