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The map label for this gene is cdh [H]

Identifier: 157372978

GI number: 157372978

Start: 5250242

End: 5251039

Strand: Direct

Name: cdh [H]

Synonym: Spro_4746

Alternate gene names: 157372978

Gene position: 5250242-5251039 (Clockwise)

Preceding gene: 157372977

Following gene: 157372981

Centisome position: 96.35

GC content: 57.77

Gene sequence:

>798_bases
ATGCTTCTCCTTTTACGGAAATGGAAATCAATCATGTCTTTGCGCCGCAGGCTGTTTTTGTACGTTGCGCCGTTGCTAAT
GGCCGCCATTGTCATTGCTGGTGCGCTCTGGATATGGGTGAAGCCACCCCAGTCGAGCGCGCTGTGGCGCATCGTCAGCC
AACAGTGTCTGCCCAACCAACAGGCAAATAACAACCCGGCGCCCTGTGCGCAGGTGGACCCTCAGGCCGGTTTTGTGGTG
TTTAAGGACCGTAACGGGCCACTGCAATATCTGTTGATGCCAAGCGCTAAAATTACCGGCATTGAAAGCCCCGAGGTACT
GGCTGCCACGACCCCAAACTTCTTTGAGCAAGCCTGGCAGGCACGGCACTTTATGGCCGATAAGTACGGCAAGGCGATCG
ACGACGCCGATATTTCGCTGGCGATTAATTCGGCCTATGGCCGCACTCAGAACCAGTTGCACATTCATATCTCGTGCCTG
CTGCCTGCGGTAAAAACGCAGCTGGCGCAGTATGCGGCAGATTACAGCGAGCGGTGGGAACCGTTGCCTGGCGGCCTGCT
GGGCCATGACTATCTGGTGCGCCGGGTGACGCCTGAAGAGTTGCACAAACAGGGTGCTTTCCGCCTGCTGGCAGATGAGG
TAGCACGCTCAAAGGGGCGCATGGGGAGCTTTGGCCTGGCGATGACCGCACTGCCGGGTGGCGATTTTCTGTTGCTGGCC
ACCGAGCGCAGCCTGCTGCCGTTTACGCTGGCTTCGTCAGAAGAGATCCAGGATCACGACTGCCGGGTTCTGCAGTAA

Upstream 100 bases:

>100_bases
AAGAAACCCGCGACCAGTCGCTGTAACCCTGCTTATGCGGCCCCTGCCTGCGGGCCGCACTCCCCGCGTTGTCTCCTGTC
ATAAAATCAGACTATGCTGA

Downstream 100 bases:

>100_bases
GCATGGCCCGCAGTGCGGGCCGTTAGCGATCATTTTTTCTGCTTCATCTGCTGAAGGATTTTACCGCACTGGTTTTCTTC
ACCGCCTTCGCTGGGGGAAA

Product: CDP-diacylglycerol pyrophosphatase

Products: NA

Alternate protein names: CDP-diacylglycerol phosphatidylhydrolase; CDP-diglyceride hydrolase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLLLLRKWKSIMSLRRRLFLYVAPLLMAAIVIAGALWIWVKPPQSSALWRIVSQQCLPNQQANNNPAPCAQVDPQAGFVV
FKDRNGPLQYLLMPSAKITGIESPEVLAATTPNFFEQAWQARHFMADKYGKAIDDADISLAINSAYGRTQNQLHIHISCL
LPAVKTQLAQYAADYSERWEPLPGGLLGHDYLVRRVTPEELHKQGAFRLLADEVARSKGRMGSFGLAMTALPGGDFLLLA
TERSLLPFTLASSEEIQDHDCRVLQ

Sequences:

>Translated_265_residues
MLLLLRKWKSIMSLRRRLFLYVAPLLMAAIVIAGALWIWVKPPQSSALWRIVSQQCLPNQQANNNPAPCAQVDPQAGFVV
FKDRNGPLQYLLMPSAKITGIESPEVLAATTPNFFEQAWQARHFMADKYGKAIDDADISLAINSAYGRTQNQLHIHISCL
LPAVKTQLAQYAADYSERWEPLPGGLLGHDYLVRRVTPEELHKQGAFRLLADEVARSKGRMGSFGLAMTALPGGDFLLLA
TERSLLPFTLASSEEIQDHDCRVLQ
>Mature_265_residues
MLLLLRKWKSIMSLRRRLFLYVAPLLMAAIVIAGALWIWVKPPQSSALWRIVSQQCLPNQQANNNPAPCAQVDPQAGFVV
FKDRNGPLQYLLMPSAKITGIESPEVLAATTPNFFEQAWQARHFMADKYGKAIDDADISLAINSAYGRTQNQLHIHISCL
LPAVKTQLAQYAADYSERWEPLPGGLLGHDYLVRRVTPEELHKQGAFRLLADEVARSKGRMGSFGLAMTALPGGDFLLLA
TERSLLPFTLASSEEIQDHDCRVLQ

Specific function: Phospholipid biosynthesis. [C]

COG id: COG2134

COG function: function code I; CDP-diacylglycerol pyrophosphatase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cdh family [H]

Homologues:

Organism=Escherichia coli, GI1790352, Length=241, Percent_Identity=53.5269709543568, Blast_Score=270, Evalue=8e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003763 [H]

Pfam domain/function: PF02611 CDH [H]

EC number: =3.6.1.26 [H]

Molecular weight: Translated: 29537; Mature: 29537

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLLRKWKSIMSLRRRLFLYVAPLLMAAIVIAGALWIWVKPPQSSALWRIVSQQCLPNQ
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCC
QANNNPAPCAQVDPQAGFVVFKDRNGPLQYLLMPSAKITGIESPEVLAATTPNFFEQAWQ
CCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCEECCCCCCCEEEECCCHHHHHHHH
ARHFMADKYGKAIDDADISLAINSAYGRTQNQLHIHISCLLPAVKTQLAQYAADYSERWE
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
PLPGGLLGHDYLVRRVTPEELHKQGAFRLLADEVARSKGRMGSFGLAMTALPGGDFLLLA
CCCCCCCCCHHHHHCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEE
TERSLLPFTLASSEEIQDHDCRVLQ
ECCCCCEEEECCCCCCCCCCCEECC
>Mature Secondary Structure
MLLLLRKWKSIMSLRRRLFLYVAPLLMAAIVIAGALWIWVKPPQSSALWRIVSQQCLPNQ
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCC
QANNNPAPCAQVDPQAGFVVFKDRNGPLQYLLMPSAKITGIESPEVLAATTPNFFEQAWQ
CCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCEECCCCCCCEEEECCCHHHHHHHH
ARHFMADKYGKAIDDADISLAINSAYGRTQNQLHIHISCLLPAVKTQLAQYAADYSERWE
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
PLPGGLLGHDYLVRRVTPEELHKQGAFRLLADEVARSKGRMGSFGLAMTALPGGDFLLLA
CCCCCCCCCHHHHHCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEE
TERSLLPFTLASSEEIQDHDCRVLQ
ECCCCCEEEECCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]