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The map label for this gene is iolB [H]

Identifier: 157372894

GI number: 157372894

Start: 5152156

End: 5152977

Strand: Reverse

Name: iolB [H]

Synonym: Spro_4662

Alternate gene names: 157372894

Gene position: 5152977-5152156 (Counterclockwise)

Preceding gene: 157372895

Following gene: 157372891

Centisome position: 94.57

GC content: 59.12

Gene sequence:

>822_bases
ATGTCTTCATTACTTGCCAAGTGTCAGCAGCCGGATGACCAGGGCCGCATCCAGCATGTCACCCCCGAGAACGCCGACTG
GCGCTTTGTCGGCTTTGATGTTTATCGCCTTGAGGCCGGCCAGTCGCTGCGGTTGGAAAGCGGCGACAAAGAGCTGTGCC
TGGTGTTGGTCGCCGGCATCGCCTCCGTCGCCACTCTGCGTGCGGAATACCCGAGCATCGGCAAACGCATGAGCCCGTTT
GAACGCACACCGCCTTATGCGGTATACGTGCCGCATCACGACAAGATTGAAGTGCGGGCGGAAAGCGCCCTGGAATTGGC
GGTCTGCAGCGCCCCGGGTCATGGGCATCTGCCGTCGCGCTTGATCACCCCGGCGGAGGTCGGCGTCGAACGTCGTGGCA
AAGGGCGTAACCAGCGTCTGGTACACAACATTCTGCCGGACAGCGAACCGGCTGACAGCCTGCTGGTGGTGGAGGTGTAT
ACGGATGAGGGTAATACCAGTTCGTACCCCAGCCACAAGCATGACCAGGAAAACTCGCCGGATGAAACCTATCTGGAAGA
GACCTATTATCATCGGATCCAGCCGGAACAGGGTTTTTGCATGCAGCGGGTGTATACCGACGATCGCTCACTGGATGAGT
GTATGCCGGTGTATAACCGTGACGTGGTCAAGGTACCACGCGGCTACCACCCGGTGGCGACATTGGCCGGTTACGACAGC
TACTATCTCAACGTGATGGCCGGGCCGGTGCGGCTGTGGAAGTTCACCTGGGAAAAAGACCACGCCTGGATTAACACCGA
CGGCTACCCCGCAGCAAAATAA

Upstream 100 bases:

>100_bases
CCGACGTTGGGTTAAGCCCATTTAGGCAACAGGGGCCGTTATTCCAATGGAGTAGCGGCCGTTGTCGTTTTACCGAATCG
CCAGGTTACAGGAGGAGTCT

Downstream 100 bases:

>100_bases
TTGCCTATTTACGACGTTGCCAAGATGAGCGTCACCCTCTCCAGGGGGAGAGGGCCGGGGTGAGGGGATTTCACGCCACT
ATGCCTACCCTTTCCCAAGG

Product: myo-inositol catabolism IolB domain-containing protein

Products: NA

Alternate protein names: 5DG isomerase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSSLLAKCQQPDDQGRIQHVTPENADWRFVGFDVYRLEAGQSLRLESGDKELCLVLVAGIASVATLRAEYPSIGKRMSPF
ERTPPYAVYVPHHDKIEVRAESALELAVCSAPGHGHLPSRLITPAEVGVERRGKGRNQRLVHNILPDSEPADSLLVVEVY
TDEGNTSSYPSHKHDQENSPDETYLEETYYHRIQPEQGFCMQRVYTDDRSLDECMPVYNRDVVKVPRGYHPVATLAGYDS
YYLNVMAGPVRLWKFTWEKDHAWINTDGYPAAK

Sequences:

>Translated_273_residues
MSSLLAKCQQPDDQGRIQHVTPENADWRFVGFDVYRLEAGQSLRLESGDKELCLVLVAGIASVATLRAEYPSIGKRMSPF
ERTPPYAVYVPHHDKIEVRAESALELAVCSAPGHGHLPSRLITPAEVGVERRGKGRNQRLVHNILPDSEPADSLLVVEVY
TDEGNTSSYPSHKHDQENSPDETYLEETYYHRIQPEQGFCMQRVYTDDRSLDECMPVYNRDVVKVPRGYHPVATLAGYDS
YYLNVMAGPVRLWKFTWEKDHAWINTDGYPAAK
>Mature_272_residues
SSLLAKCQQPDDQGRIQHVTPENADWRFVGFDVYRLEAGQSLRLESGDKELCLVLVAGIASVATLRAEYPSIGKRMSPFE
RTPPYAVYVPHHDKIEVRAESALELAVCSAPGHGHLPSRLITPAEVGVERRGKGRNQRLVHNILPDSEPADSLLVVEVYT
DEGNTSSYPSHKHDQENSPDETYLEETYYHRIQPEQGFCMQRVYTDDRSLDECMPVYNRDVVKVPRGYHPVATLAGYDSY
YLNVMAGPVRLWKFTWEKDHAWINTDGYPAAK

Specific function: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) [H]

COG id: COG3718

COG function: function code G; Uncharacterized enzyme involved in inositol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isomerase iolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR021120
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04962 KduI [H]

EC number: NA

Molecular weight: Translated: 30905; Mature: 30774

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLAKCQQPDDQGRIQHVTPENADWRFVGFDVYRLEAGQSLRLESGDKELCLVLVAGI
CCCHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHH
ASVATLRAEYPSIGKRMSPFERTPPYAVYVPHHDKIEVRAESALELAVCSAPGHGHLPSR
HHHHHHHHHCCHHCCCCCCCCCCCCEEEECCCCCCEEEEECCCEEEEEECCCCCCCCCHH
LITPAEVGVERRGKGRNQRLVHNILPDSEPADSLLVVEVYTDEGNTSSYPSHKHDQENSP
CCCHHHHCHHHCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
DETYLEETYYHRIQPEQGFCMQRVYTDDRSLDECMPVYNRDVVKVPRGYHPVATLAGYDS
CHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCCCEEECCCCCCCHHHHCCCCC
YYLNVMAGPVRLWKFTWEKDHAWINTDGYPAAK
EEEEEEECCEEEEEEEECCCCEEECCCCCCCCC
>Mature Secondary Structure 
SSLLAKCQQPDDQGRIQHVTPENADWRFVGFDVYRLEAGQSLRLESGDKELCLVLVAGI
CCHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHH
ASVATLRAEYPSIGKRMSPFERTPPYAVYVPHHDKIEVRAESALELAVCSAPGHGHLPSR
HHHHHHHHHCCHHCCCCCCCCCCCCEEEECCCCCCEEEEECCCEEEEEECCCCCCCCCHH
LITPAEVGVERRGKGRNQRLVHNILPDSEPADSLLVVEVYTDEGNTSSYPSHKHDQENSP
CCCHHHHCHHHCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
DETYLEETYYHRIQPEQGFCMQRVYTDDRSLDECMPVYNRDVVKVPRGYHPVATLAGYDS
CHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCCCEEECCCCCCCHHHHCCCCC
YYLNVMAGPVRLWKFTWEKDHAWINTDGYPAAK
EEEEEEECCEEEEEEEECCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA