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The map label for this gene is nahR [H]

Identifier: 157372854

GI number: 157372854

Start: 5097847

End: 5098791

Strand: Reverse

Name: nahR [H]

Synonym: Spro_4622

Alternate gene names: 157372854

Gene position: 5098791-5097847 (Counterclockwise)

Preceding gene: 157372863

Following gene: 157372853

Centisome position: 93.58

GC content: 56.08

Gene sequence:

>945_bases
ATGAATTTGAAGAACGTCGATTTGAATTTATTGGTGGTGTTTGACGCTATCTTTCGCCAGCGTAGCGTCGGCCTGGCGGG
GCAGATGCTGGGTATCAGCCAGCCGGCGGTGAGCCATGCGCTGGCTCGCCTGCGTCAACTGTTTGACGACCCGATGTTTG
TGCGGATTAATAACGAAATGCGCCCGACTGACCGGGCCAGTGAACTGATGCCCTCCGTCGAGCGGGTGCTGTCGATGATC
CGCGACGATGTTTTGCAACCGGTGGGGTTTGATCCTGCGGCTAACCGCAGAACGCTAACGCTCTGTATGCCGGACATCGG
AGAGCAGTATTTTTTACCTCCTCTGATTAACCATCTGGCCCAGGTGGCTCCGGGGATGGCGGTGGTCAGCCATGAGCTGG
CTCCGGCGCAATTGGAAGAGGCGCTGGAAAGCGGGCGGGTCGATCTGGCTATCGGCTATTTTCCCGACCTGCGTCGCGCC
GTTTTTTATCAGCAGCGGTTATTTTACAGTGGATTCTGCTGTGCGGTGCGCCAGGGCCATCCGCAGATTGGCAAAACACT
GTCATTGCCGCAGTTCTTGCAGGCTGAACACGTGACCGCTCGTTTGCGTATTCGCAGCCAGGAAATTGCTGAACAGGCGA
TGAGGGAGCAGGGGATTGTGCGCAACGTCAAACTGCAGACCAGCCACTTTCTGAGCCTGACCCAGATCATTGCCCAAACG
GACCTGCTTGCCACGGTGACCTATGAGGCGGCACAGTTACTGCAGGCTGCGGGTAAGGTGCATATTTATCCGGTGCCTTT
CCCAATACCTCAGTTCCCGGTGATGCAGTATTGGCATGAGCGCGCTCATCATGACCGTGGCAATCAATGGCTGCGGGGCG
AAATACGAGGGTTATTCCAACGCGATAACGACAATAGTGCCGATGAATGCACGGCAGAACATTAG

Upstream 100 bases:

>100_bases
ATGCATTTTTGTTAATGAAATGAAAATTCTTATGTACTGAGAGAATATCTGCTGCCTACAATCAATCAATCGAATGTGAT
TTATTGGGCGAATAAGAAAA

Downstream 100 bases:

>100_bases
GTGCATTGTCACTGGCGGCTTAGACTGAGGCTACACTCGCCGGAATCAGGGCTAATCAGGTTATAAATACGTTATTAATT
TGAGGGCCAGTCCCCAGCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MNLKNVDLNLLVVFDAIFRQRSVGLAGQMLGISQPAVSHALARLRQLFDDPMFVRINNEMRPTDRASELMPSVERVLSMI
RDDVLQPVGFDPAANRRTLTLCMPDIGEQYFLPPLINHLAQVAPGMAVVSHELAPAQLEEALESGRVDLAIGYFPDLRRA
VFYQQRLFYSGFCCAVRQGHPQIGKTLSLPQFLQAEHVTARLRIRSQEIAEQAMREQGIVRNVKLQTSHFLSLTQIIAQT
DLLATVTYEAAQLLQAAGKVHIYPVPFPIPQFPVMQYWHERAHHDRGNQWLRGEIRGLFQRDNDNSADECTAEH

Sequences:

>Translated_314_residues
MNLKNVDLNLLVVFDAIFRQRSVGLAGQMLGISQPAVSHALARLRQLFDDPMFVRINNEMRPTDRASELMPSVERVLSMI
RDDVLQPVGFDPAANRRTLTLCMPDIGEQYFLPPLINHLAQVAPGMAVVSHELAPAQLEEALESGRVDLAIGYFPDLRRA
VFYQQRLFYSGFCCAVRQGHPQIGKTLSLPQFLQAEHVTARLRIRSQEIAEQAMREQGIVRNVKLQTSHFLSLTQIIAQT
DLLATVTYEAAQLLQAAGKVHIYPVPFPIPQFPVMQYWHERAHHDRGNQWLRGEIRGLFQRDNDNSADECTAEH
>Mature_314_residues
MNLKNVDLNLLVVFDAIFRQRSVGLAGQMLGISQPAVSHALARLRQLFDDPMFVRINNEMRPTDRASELMPSVERVLSMI
RDDVLQPVGFDPAANRRTLTLCMPDIGEQYFLPPLINHLAQVAPGMAVVSHELAPAQLEEALESGRVDLAIGYFPDLRRA
VFYQQRLFYSGFCCAVRQGHPQIGKTLSLPQFLQAEHVTARLRIRSQEIAEQAMREQGIVRNVKLQTSHFLSLTQIIAQT
DLLATVTYEAAQLLQAAGKVHIYPVPFPIPQFPVMQYWHERAHHDRGNQWLRGEIRGLFQRDNDNSADECTAEH

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=28.4280936454849, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786820, Length=252, Percent_Identity=26.5873015873016, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790147, Length=313, Percent_Identity=25.2396166134185, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87081766, Length=265, Percent_Identity=23.3962264150943, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35556; Mature: 35556

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKNVDLNLLVVFDAIFRQRSVGLAGQMLGISQPAVSHALARLRQLFDDPMFVRINNEM
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
RPTDRASELMPSVERVLSMIRDDVLQPVGFDPAANRRTLTLCMPDIGEQYFLPPLINHLA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
QVAPGMAVVSHELAPAQLEEALESGRVDLAIGYFPDLRRAVFYQQRLFYSGFCCAVRQGH
HHCCCHHHHHHCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PQIGKTLSLPQFLQAEHVTARLRIRSQEIAEQAMREQGIVRNVKLQTSHFLSLTQIIAQT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHHHHHHH
DLLATVTYEAAQLLQAAGKVHIYPVPFPIPQFPVMQYWHERAHHDRGNQWLRGEIRGLFQ
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RDNDNSADECTAEH
CCCCCCCCCCCCCC
>Mature Secondary Structure
MNLKNVDLNLLVVFDAIFRQRSVGLAGQMLGISQPAVSHALARLRQLFDDPMFVRINNEM
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
RPTDRASELMPSVERVLSMIRDDVLQPVGFDPAANRRTLTLCMPDIGEQYFLPPLINHLA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
QVAPGMAVVSHELAPAQLEEALESGRVDLAIGYFPDLRRAVFYQQRLFYSGFCCAVRQGH
HHCCCHHHHHHCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PQIGKTLSLPQFLQAEHVTARLRIRSQEIAEQAMREQGIVRNVKLQTSHFLSLTQIIAQT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHHHHHHH
DLLATVTYEAAQLLQAAGKVHIYPVPFPIPQFPVMQYWHERAHHDRGNQWLRGEIRGLFQ
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RDNDNSADECTAEH
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]