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The map label for this gene is argD [H]

Identifier: 157372814

GI number: 157372814

Start: 5055721

End: 5056938

Strand: Reverse

Name: argD [H]

Synonym: Spro_4582

Alternate gene names: 157372814

Gene position: 5056938-5055721 (Counterclockwise)

Preceding gene: 157372815

Following gene: 157372811

Centisome position: 92.81

GC content: 58.13

Gene sequence:

>1218_bases
ATGACCGAAAAAACCGCAGTAAGCCGCAGTACCTTTGATCAGGTTATCCTGCCTGTTTATGCACCCGCGCAGTTTGTTCC
GGTCAGGGGCAAAGGCAGCCGCGTGTGGGACAGCCAAGGGAAAGAGTACATTGATTTCTCTGGCGGCATTGCGGTGACGG
CGTTAGGGCACTGTCACCCGGCCCTGGTCGAAGCGCTGAAACAGCAGGGCGAAACCCTGTGGCATACCAGCAACGTTTTT
ACTAACGAGCCGGCGCTGCGGCTGGCCACCAAGTTGATCAACGCCACCTTTGCCGACCGGGTGTTTTTTGCCAACTCCGG
CGCAGAGGCTAACGAAGCGGCCTTCAAACTGGCGCGTCATTACGCCATTACCCGCCACAGCCCGTACAAAACCAAAATCA
TCGCGTTTTATAACGCTTTCCACGGTCGCACGCTATTCACCGTCTCGGTGGGCGGGCAGGCCAAGTATTCGGATGGTTTT
GGGCCAAAACCGGCCGACATCGTGCACGTGCCGTTCAACGATTTGGCGGCGGTGAAAGCAGTGATGGACGACCATACCTG
TGCGGTGGTGATGGAGCCAATCCAGGGCGAAGGGGGCATTACTCCGGTTAATGCCGAATTCCTCAAGGGCGTGCGTGAAC
TGTGCGATAAACACCAGGCACTGCTGGTATTCGACGAAGTGCAAAGCGGCATGGGGCGCAGCGGCAAACTGTTTGCCTAT
ATGCACTATGGCGTGACGCCGGACATTCTCACCACGGCCAAAGCGCTTGGCGGCGGTTTCCCGGTCAGCGCCATGCTGAC
CACCGAAGAGATTGCCTCGGTGATGCAGGTTGGTACCCACGGCACCACCTACGGCGGCAATCCGCTGGCCTGCGCGGTGG
CGGAAGCGGCGCTGGACGTGATCAATACGCCGGAAGTGCTGAGTGGCATTGAGTTGCGTCATGGGCTATACGTGCAGGCG
TTAAAGAAAATTGGCGATAAGTACGGTATTTTCAGCGATATTCGCGGCATGGGCCTGCTGATTGGTGCTGAATTAACACC
GCAATACCAGGGTAAGGCGCGCGATTTCCTGACCGCCGCCGCCGCACGTGGGCTGATGATCCTCAATGCCGGGCCAAATG
TGATCCGCTTTGCGCCTTCGCTGGTGGTGGAGACCCAGGACATCGACGAAGGGATGGCGCTGTTTGAGCTGGCGGTGCAG
GACGTGATTGACGCGTAA

Upstream 100 bases:

>100_bases
TTTGCGTTTGCCCTTTATTGGTTTTTTATGCATATTTTGTGATTATATTTTCACTCAATTGCAACCAAAAGACTGAGTCA
TATTCAGGGTGGGCCACATA

Downstream 100 bases:

>100_bases
TGCGTTGCATTGATGACAAGGGCGCCAGACGGCGCCCTTATTGATCGCGCAGTTTGCGTTTCAGCCAGATGCCGTGGTGT
GGGCGTTGGCTCCAGGCCAA

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTEKTAVSRSTFDQVILPVYAPAQFVPVRGKGSRVWDSQGKEYIDFSGGIAVTALGHCHPALVEALKQQGETLWHTSNVF
TNEPALRLATKLINATFADRVFFANSGAEANEAAFKLARHYAITRHSPYKTKIIAFYNAFHGRTLFTVSVGGQAKYSDGF
GPKPADIVHVPFNDLAAVKAVMDDHTCAVVMEPIQGEGGITPVNAEFLKGVRELCDKHQALLVFDEVQSGMGRSGKLFAY
MHYGVTPDILTTAKALGGGFPVSAMLTTEEIASVMQVGTHGTTYGGNPLACAVAEAALDVINTPEVLSGIELRHGLYVQA
LKKIGDKYGIFSDIRGMGLLIGAELTPQYQGKARDFLTAAAARGLMILNAGPNVIRFAPSLVVETQDIDEGMALFELAVQ
DVIDA

Sequences:

>Translated_405_residues
MTEKTAVSRSTFDQVILPVYAPAQFVPVRGKGSRVWDSQGKEYIDFSGGIAVTALGHCHPALVEALKQQGETLWHTSNVF
TNEPALRLATKLINATFADRVFFANSGAEANEAAFKLARHYAITRHSPYKTKIIAFYNAFHGRTLFTVSVGGQAKYSDGF
GPKPADIVHVPFNDLAAVKAVMDDHTCAVVMEPIQGEGGITPVNAEFLKGVRELCDKHQALLVFDEVQSGMGRSGKLFAY
MHYGVTPDILTTAKALGGGFPVSAMLTTEEIASVMQVGTHGTTYGGNPLACAVAEAALDVINTPEVLSGIELRHGLYVQA
LKKIGDKYGIFSDIRGMGLLIGAELTPQYQGKARDFLTAAAARGLMILNAGPNVIRFAPSLVVETQDIDEGMALFELAVQ
DVIDA
>Mature_404_residues
TEKTAVSRSTFDQVILPVYAPAQFVPVRGKGSRVWDSQGKEYIDFSGGIAVTALGHCHPALVEALKQQGETLWHTSNVFT
NEPALRLATKLINATFADRVFFANSGAEANEAAFKLARHYAITRHSPYKTKIIAFYNAFHGRTLFTVSVGGQAKYSDGFG
PKPADIVHVPFNDLAAVKAVMDDHTCAVVMEPIQGEGGITPVNAEFLKGVRELCDKHQALLVFDEVQSGMGRSGKLFAYM
HYGVTPDILTTAKALGGGFPVSAMLTTEEIASVMQVGTHGTTYGGNPLACAVAEAALDVINTPEVLSGIELRHGLYVQAL
KKIGDKYGIFSDIRGMGLLIGAELTPQYQGKARDFLTAAAARGLMILNAGPNVIRFAPSLVVETQDIDEGMALFELAVQD
VIDA

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=36.9897959183673, Blast_Score=231, Evalue=9e-61,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=37.6666666666667, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI13994255, Length=422, Percent_Identity=28.9099526066351, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI37574042, Length=401, Percent_Identity=30.4239401496259, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI226442709, Length=374, Percent_Identity=30.7486631016043, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI24119277, Length=414, Percent_Identity=28.2608695652174, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI226442705, Length=401, Percent_Identity=29.426433915212, Blast_Score=133, Evalue=3e-31,
Organism=Escherichia coli, GI1789759, Length=403, Percent_Identity=76.6749379652606, Blast_Score=660, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=397, Percent_Identity=61.4609571788413, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1789016, Length=420, Percent_Identity=34.7619047619048, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI145693181, Length=330, Percent_Identity=36.6666666666667, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787560, Length=410, Percent_Identity=35.1219512195122, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1786991, Length=413, Percent_Identity=30.7506053268765, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786349, Length=335, Percent_Identity=30.7462686567164, Blast_Score=121, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=387, Percent_Identity=36.1757105943152, Blast_Score=238, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI32564660, Length=422, Percent_Identity=31.7535545023697, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI25144274, Length=266, Percent_Identity=37.593984962406, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71992977, Length=420, Percent_Identity=30, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17541228, Length=436, Percent_Identity=25, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=165, Percent_Identity=31.5151515151515, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=40.4040404040404, Blast_Score=299, Evalue=7e-82,
Organism=Saccharomyces cerevisiae, GI6323470, Length=417, Percent_Identity=35.2517985611511, Blast_Score=219, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=30.2547770700637, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6321456, Length=429, Percent_Identity=24.009324009324, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=35.4497354497354, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=29.81220657277, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI161085790, Length=423, Percent_Identity=30.0236406619385, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21356575, Length=444, Percent_Identity=28.3783783783784, Blast_Score=145, Evalue=5e-35,
Organism=Drosophila melanogaster, GI281366494, Length=432, Percent_Identity=22.6851851851852, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667139, Length=432, Percent_Identity=22.6851851851852, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667143, Length=432, Percent_Identity=22.6851851851852, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11; =2.6.1.17 [H]

Molecular weight: Translated: 43436; Mature: 43305

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKTAVSRSTFDQVILPVYAPAQFVPVRGKGSRVWDSQGKEYIDFSGGIAVTALGHCHP
CCCCHHCCHHHHHHHEEEEECCCEEEEECCCCCCCCCCCCCEEEEECCCEEEEEECCCCH
ALVEALKQQGETLWHTSNVFTNEPALRLATKLINATFADRVFFANSGAEANEAAFKLARH
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHH
YAITRHSPYKTKIIAFYNAFHGRTLFTVSVGGQAKYSDGFGPKPADIVHVPFNDLAAVKA
HHHCCCCCCCEEEEEEEECCCCCEEEEEEECCCEEECCCCCCCCCCEEEECCHHHHHHHH
VMDDHTCAVVMEPIQGEGGITPVNAEFLKGVRELCDKHQALLVFDEVQSGMGRSGKLFAY
HHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEEE
MHYGVTPDILTTAKALGGGFPVSAMLTTEEIASVMQVGTHGTTYGGNPLACAVAEAALDV
EECCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
INTPEVLSGIELRHGLYVQALKKIGDKYGIFSDIRGMGLLIGAELTPQYQGKARDFLTAA
CCCHHHHHCHHHHCCHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCCCCCCHHHHHHHHH
AARGLMILNAGPNVIRFAPSLVVETQDIDEGMALFELAVQDVIDA
HHCCEEEEECCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEKTAVSRSTFDQVILPVYAPAQFVPVRGKGSRVWDSQGKEYIDFSGGIAVTALGHCHP
CCCHHCCHHHHHHHEEEEECCCEEEEECCCCCCCCCCCCCEEEEECCCEEEEEECCCCH
ALVEALKQQGETLWHTSNVFTNEPALRLATKLINATFADRVFFANSGAEANEAAFKLARH
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHH
YAITRHSPYKTKIIAFYNAFHGRTLFTVSVGGQAKYSDGFGPKPADIVHVPFNDLAAVKA
HHHCCCCCCCEEEEEEEECCCCCEEEEEEECCCEEECCCCCCCCCCEEEECCHHHHHHHH
VMDDHTCAVVMEPIQGEGGITPVNAEFLKGVRELCDKHQALLVFDEVQSGMGRSGKLFAY
HHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEEE
MHYGVTPDILTTAKALGGGFPVSAMLTTEEIASVMQVGTHGTTYGGNPLACAVAEAALDV
EECCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
INTPEVLSGIELRHGLYVQALKKIGDKYGIFSDIRGMGLLIGAELTPQYQGKARDFLTAA
CCCHHHHHCHHHHCCHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCCCCCCHHHHHHHHH
AARGLMILNAGPNVIRFAPSLVVETQDIDEGMALFELAVQDVIDA
HHCCEEEEECCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]