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The map label for this gene is uxaC

Identifier: 157372554

GI number: 157372554

Start: 4791513

End: 4792925

Strand: Reverse

Name: uxaC

Synonym: Spro_4321

Alternate gene names: 157372554

Gene position: 4792925-4791513 (Counterclockwise)

Preceding gene: 157372566

Following gene: 157372553

Centisome position: 87.96

GC content: 56.4

Gene sequence:

>1413_bases
ATGGCGACGTTTTTAAGCGAAGATTTTCTGTTGGGCAATGAATTTGCCCGACGTTTGTATCATGACTATGCGGCAGACCA
GCCGATCTTTGACTATCACTGTCATTTACCGCCGGAGCAGATCGCCGAGAACACCCGCTTCAAAAATTTATATGAGATCT
GGCTAAAGGGCGATCACTATAAATGGCGGGCGATGCGCACCAACGGTGTGGCTGAGCGGCTGTGTACCGGGGATGCCGGT
GACCGTGAAAAGTTTGATGCCTGGGCCGCTACCGTGCCGCATACCATAGGTAATCCGCTCTACCACTGGACTCATCTGGA
GCTGCGCCGCCCGTTCGGGATTACCGGCACGCTGCTTTCCCCAACGACTGCGGACGATATCTGGCAGCGGGGCAACGCCT
TGCTGGCGCAGGATGATTTCAGGGCGCGTGGCATCATGCAGCAAATGAATGTGAAGATGGTTGGTACTACCGACGATCCG
ATCGACGATTTGCGCCACCATAAAGCGATTGCGGCTGACAGTAGCTTCGATATCAAGGTGTTGCCAAGCTGGCGACCGGA
CAAGGCGTTCAATATCGACGCGCCGGGTTTCAATGATTACCTGCAAAAACTGGAAGCGGCGGCGGATATCAATATTGGCC
GGTTTAGCGCGCTGTGTGACGCGTTGAAAAAACGCATGGATCATTTTGCCGCCCATGGCTGCAAGGTGGCTGACCATGCG
CTGGACGTGGTGGTGTATGGCGAAGCGGACGAAAGCACATTGGACGCGATTTTAACCGCGCGCCTGAGTGGCAAGCTGCC
GACGCCGGAGCAGAGCGCCCAGTTCAAAAGTGCGGTACTGCTGTTCCTGGCCGCCGAATATCAACGTCGTGAATGGGTAC
AGCAGTATCACATCGGCGCGCTGCGCAATAATAACAGCCGTATGCTCGCCAGTGTGGGGCCGGACATCGGCTTCGACTCG
ATTAACGACCGGCCGCTGGCGGAGGCGCTTTCTCGCCTGCTGGATGCCCAGGCACGCCAGGGCGGCCTGCCGAAAACTAT
TCTGTACTGCCTGAACCCGCGCGACAACGAAGTGATCGGCACCATGGTCGGCAACTTCCAGGGGGAGGGCACGCCGGGCA
AGATGCAGTTCGGCTCCGGCTGGTGGTTCAACGATCAAAAAGACGGTATGCAGCGGCAAATGACGCAGTTGGCGCAACTG
GGCCTGCTGAGCCGTTTTGTCGGCATGCTGACCGACAGCCGCAGTTTCTTGTCTTATACCCGTCATGAATATTTCCGCCG
CATCCTTTGCCAGATGATTGGCGGCTGGGTGGAGAACGGGGAAGCGCCGGCGGATATCACGTTACTGGGTGAGATGGTGA
AAAACATCTGTTTCGACAATGCCAAAAACTATTTCGCCATTGAACTGGCCTAG

Upstream 100 bases:

>100_bases
ATAGGGTGATATTTTGCTGGACGCTCAGTGAAATTGGTGTGATAACTTTGTCGCATTGGACAGAGTACCGAACGGCAAGC
AAGGCGAGGAACCAAAAAAG

Downstream 100 bases:

>100_bases
CCGTTGCCCGAGGTGGGTTTATGCAAAGCATGGTAAAAATTCATTCGCTGGATAATGTCGCGGTAGCGCTGAGCGATCTG
GCCGCCGGCGAAACCTTGGC

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MATFLSEDFLLGNEFARRLYHDYAADQPIFDYHCHLPPEQIAENTRFKNLYEIWLKGDHYKWRAMRTNGVAERLCTGDAG
DREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGTLLSPTTADDIWQRGNALLAQDDFRARGIMQQMNVKMVGTTDDP
IDDLRHHKAIAADSSFDIKVLPSWRPDKAFNIDAPGFNDYLQKLEAAADINIGRFSALCDALKKRMDHFAAHGCKVADHA
LDVVVYGEADESTLDAILTARLSGKLPTPEQSAQFKSAVLLFLAAEYQRREWVQQYHIGALRNNNSRMLASVGPDIGFDS
INDRPLAEALSRLLDAQARQGGLPKTILYCLNPRDNEVIGTMVGNFQGEGTPGKMQFGSGWWFNDQKDGMQRQMTQLAQL
GLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGGWVENGEAPADITLLGEMVKNICFDNAKNYFAIELA

Sequences:

>Translated_470_residues
MATFLSEDFLLGNEFARRLYHDYAADQPIFDYHCHLPPEQIAENTRFKNLYEIWLKGDHYKWRAMRTNGVAERLCTGDAG
DREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGTLLSPTTADDIWQRGNALLAQDDFRARGIMQQMNVKMVGTTDDP
IDDLRHHKAIAADSSFDIKVLPSWRPDKAFNIDAPGFNDYLQKLEAAADINIGRFSALCDALKKRMDHFAAHGCKVADHA
LDVVVYGEADESTLDAILTARLSGKLPTPEQSAQFKSAVLLFLAAEYQRREWVQQYHIGALRNNNSRMLASVGPDIGFDS
INDRPLAEALSRLLDAQARQGGLPKTILYCLNPRDNEVIGTMVGNFQGEGTPGKMQFGSGWWFNDQKDGMQRQMTQLAQL
GLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGGWVENGEAPADITLLGEMVKNICFDNAKNYFAIELA
>Mature_469_residues
ATFLSEDFLLGNEFARRLYHDYAADQPIFDYHCHLPPEQIAENTRFKNLYEIWLKGDHYKWRAMRTNGVAERLCTGDAGD
REKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGTLLSPTTADDIWQRGNALLAQDDFRARGIMQQMNVKMVGTTDDPI
DDLRHHKAIAADSSFDIKVLPSWRPDKAFNIDAPGFNDYLQKLEAAADINIGRFSALCDALKKRMDHFAAHGCKVADHAL
DVVVYGEADESTLDAILTARLSGKLPTPEQSAQFKSAVLLFLAAEYQRREWVQQYHIGALRNNNSRMLASVGPDIGFDSI
NDRPLAEALSRLLDAQARQGGLPKTILYCLNPRDNEVIGTMVGNFQGEGTPGKMQFGSGWWFNDQKDGMQRQMTQLAQLG
LLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGGWVENGEAPADITLLGEMVKNICFDNAKNYFAIELA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family

Homologues:

Organism=Escherichia coli, GI2367192, Length=469, Percent_Identity=79.1044776119403, Blast_Score=796, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXAC_SERP5 (A8GJX5)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480543.1
- ProteinModelPortal:   A8GJX5
- SMR:   A8GJX5
- STRING:   A8GJX5
- GeneID:   5606957
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4321
- eggNOG:   COG1904
- HOGENOM:   HBG297087
- OMA:   AWAKTVP
- ProtClustDB:   PRK02925
- BioCyc:   SPRO399741:SPRO_4321-MONOMER
- HAMAP:   MF_00675
- InterPro:   IPR003766
- InterPro:   IPR023177
- Gene3D:   G3DSA:1.10.2020.10

Pfam domain/function: PF02614 UxaC

EC number: =5.3.1.12

Molecular weight: Translated: 53063; Mature: 52931

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFLSEDFLLGNEFARRLYHDYAADQPIFDYHCHLPPEQIAENTRFKNLYEIWLKGDHY
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCHHHHHHHHHCCCCCE
KWRAMRTNGVAERLCTGDAGDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGTLLS
EEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCCCC
PTTADDIWQRGNALLAQDDFRARGIMQQMNVKMVGTTDDPIDDLRHHKAIAADSSFDIKV
CCCHHHHHHCCCEEEECCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEE
LPSWRPDKAFNIDAPGFNDYLQKLEAAADINIGRFSALCDALKKRMDHFAAHGCKVADHA
CCCCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCE
LDVVVYGEADESTLDAILTARLSGKLPTPEQSAQFKSAVLLFLAAEYQRREWVQQYHIGA
EEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNNNSRMLASVGPDIGFDSINDRPLAEALSRLLDAQARQGGLPKTILYCLNPRDNEVIG
EECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
TMVGNFQGEGTPGKMQFGSGWWFNDQKDGMQRQMTQLAQLGLLSRFVGMLTDSRSFLSYT
EHHCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RHEYFRRILCQMIGGWVENGEAPADITLLGEMVKNICFDNAKNYFAIELA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
>Mature Secondary Structure 
ATFLSEDFLLGNEFARRLYHDYAADQPIFDYHCHLPPEQIAENTRFKNLYEIWLKGDHY
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCHHHHHHHHHCCCCCE
KWRAMRTNGVAERLCTGDAGDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGTLLS
EEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCCCC
PTTADDIWQRGNALLAQDDFRARGIMQQMNVKMVGTTDDPIDDLRHHKAIAADSSFDIKV
CCCHHHHHHCCCEEEECCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEE
LPSWRPDKAFNIDAPGFNDYLQKLEAAADINIGRFSALCDALKKRMDHFAAHGCKVADHA
CCCCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCE
LDVVVYGEADESTLDAILTARLSGKLPTPEQSAQFKSAVLLFLAAEYQRREWVQQYHIGA
EEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNNNSRMLASVGPDIGFDSINDRPLAEALSRLLDAQARQGGLPKTILYCLNPRDNEVIG
EECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
TMVGNFQGEGTPGKMQFGSGWWFNDQKDGMQRQMTQLAQLGLLSRFVGMLTDSRSFLSYT
EHHCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RHEYFRRILCQMIGGWVENGEAPADITLLGEMVKNICFDNAKNYFAIELA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA