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The map label for this gene is uup [H]

Identifier: 157372541

GI number: 157372541

Start: 4777393

End: 4779012

Strand: Reverse

Name: uup [H]

Synonym: Spro_4308

Alternate gene names: 157372541

Gene position: 4779012-4777393 (Counterclockwise)

Preceding gene: 157372545

Following gene: 157372539

Centisome position: 87.71

GC content: 61.11

Gene sequence:

>1620_bases
ATGGCTCATTTTGCGCAGTCCCCTCATCTTGTTTTACATCAACTGACCTGCCAGTTTGCTGACGGCGAAACGCTGTTCGG
CCCATTGGATCTGACTTTCGATCAACAACGCTGCGGCCTGGTTGGGCGCAACGGCGTCGGCAAAACGCGTCTGCTACGGC
TGATTGCCGGGCTGGACTTGCCGGGTAACGGCCATGTTGAATCCCATGCTTCACTGGCCTACGTGGCGCAGCAGCCGGAT
CTCGCACCGCGGACCACGCTGGCGCAGCTGCTCGGCTACGGCGAGACCTTTGCCGCGTTGGCCCGTCTTGAGCAGGGACG
ACCGCAGGCGGACGATATCGATCGTCTGGAAGGGCAATGGGATCTCAGCGATCGTCTGCAGGCCGTTTTTACCTCCGCCG
GATTGCCGCCGTTCGATCCGCAACGGCCGGCGAGCGATCTGAGCGGCGGTGAACGGATGCGTGCCGCCTTGTGCGGGGCG
ATGCTCGGCGCAGCCGACTTCCTGCTACTGGACGAACCGACCAACCACCTTGATACCCGCGCCCGCGACTGGCTGTATCA
GCAGTTGGAAAACTGGCGTGGCGGCTTGCTGGTTGCCAGCCATGATCGACAACTGCTGGCGCGTATGCAGCGCATTGTCG
AACTGACGCCCGGCGCACTGCACAGCTACGGCGGTAATTATGATGATTATCGTCACCAGCGTGATCTGGAGCAGCAGGCT
GCGCGTGCCGGACTGGAACATGCGCGTCAGGAACGTCGACGCACCCGCGCCCGGCAGCAGAAAGAACACGACATCAGCCA
ACGGCGCTCTGCGCAGACGCTGAAAACCGTCGATACGCTGAATATTGCCTCCTTTGAACGCGTGGCCTACAAGGCGGCGG
CCAAAGAGAGTTTGGGTACGCTGCGCAAGCAGCATCAGGAGCAGAAAGGCTCCCTCGATGCCGCAGTGCGTGAAGCCTGG
CAGCGGGTGGAGGAAGACAGCCCGGTGATGTTGACTCTGCCAGGCAGTACAGTGGCGGCGGGCAAACAGGTACTGGTGCT
GGAACAACTGCAACTGCCCTTTATCACTATGCCGCCGCTGGATTTACGCATCGATGGCCCGATGCGCGTGGCGTTAACCG
GCCCGAACGGCTGCGGTAAAACGACCTTGCTGAAGGTGATCCTCGGGCAGTTGGCCGCCAAAGCCGGTCGTTGCCATTGC
TTGCTACCGACGGCTTATCTCGATCAAAATCTTTCGCAGCTCGATCTGTCGCTCTCGGTGGTTGAGCACCTTGGCCTGCA
GGATTCGCCGCTAAATGAGGGCAGGATGCGCAGCCAGTTGGCACAGTTGCAGCTAAACGCCGAGCGCGTACTGTTGCCCC
TGGCGGCGCTGAGTGGCGGTGAGCGGTTGAAGGCGGCGCTGGCCTGCATGCTGTGGCGGCAGGAACCGGCGCAGTTGCTG
CTGCTGGATGAGCCGACCAACCACCTGGATCTGGCATCGTCACTGGCGATTGAGGCCGCATTGGCCAGTTTTCCCGGCGC
GATGCTGGTGGTCTCCCATGATGAAGCGTTTTTGCAGGCGCTGAAATTAACTCACCGTTTGCAATGGCGGCAGGAAGGGT
GGCAATTGCAGAGCCTTTGA

Upstream 100 bases:

>100_bases
GCCATTACCGAAAATGAACACACACGCCTGCTGATATCTTGTCCCACGTTGCGCACATCGGTGCCTTGTGGGGATGTTTT
GATCTCATTCAGGAGTGCTT

Downstream 100 bases:

>100_bases
TGGAAAACAGCGCTCAGGGACGGATGCATTCCAGCAGCAAGGTAAAGGCGGCGGCCATTTGTTCTTCTGGCACGCAGGCA
AACCCCATCAGCAGGCCACG

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MAHFAQSPHLVLHQLTCQFADGETLFGPLDLTFDQQRCGLVGRNGVGKTRLLRLIAGLDLPGNGHVESHASLAYVAQQPD
LAPRTTLAQLLGYGETFAALARLEQGRPQADDIDRLEGQWDLSDRLQAVFTSAGLPPFDPQRPASDLSGGERMRAALCGA
MLGAADFLLLDEPTNHLDTRARDWLYQQLENWRGGLLVASHDRQLLARMQRIVELTPGALHSYGGNYDDYRHQRDLEQQA
ARAGLEHARQERRRTRARQQKEHDISQRRSAQTLKTVDTLNIASFERVAYKAAAKESLGTLRKQHQEQKGSLDAAVREAW
QRVEEDSPVMLTLPGSTVAAGKQVLVLEQLQLPFITMPPLDLRIDGPMRVALTGPNGCGKTTLLKVILGQLAAKAGRCHC
LLPTAYLDQNLSQLDLSLSVVEHLGLQDSPLNEGRMRSQLAQLQLNAERVLLPLAALSGGERLKAALACMLWRQEPAQLL
LLDEPTNHLDLASSLAIEAALASFPGAMLVVSHDEAFLQALKLTHRLQWRQEGWQLQSL

Sequences:

>Translated_539_residues
MAHFAQSPHLVLHQLTCQFADGETLFGPLDLTFDQQRCGLVGRNGVGKTRLLRLIAGLDLPGNGHVESHASLAYVAQQPD
LAPRTTLAQLLGYGETFAALARLEQGRPQADDIDRLEGQWDLSDRLQAVFTSAGLPPFDPQRPASDLSGGERMRAALCGA
MLGAADFLLLDEPTNHLDTRARDWLYQQLENWRGGLLVASHDRQLLARMQRIVELTPGALHSYGGNYDDYRHQRDLEQQA
ARAGLEHARQERRRTRARQQKEHDISQRRSAQTLKTVDTLNIASFERVAYKAAAKESLGTLRKQHQEQKGSLDAAVREAW
QRVEEDSPVMLTLPGSTVAAGKQVLVLEQLQLPFITMPPLDLRIDGPMRVALTGPNGCGKTTLLKVILGQLAAKAGRCHC
LLPTAYLDQNLSQLDLSLSVVEHLGLQDSPLNEGRMRSQLAQLQLNAERVLLPLAALSGGERLKAALACMLWRQEPAQLL
LLDEPTNHLDLASSLAIEAALASFPGAMLVVSHDEAFLQALKLTHRLQWRQEGWQLQSL
>Mature_538_residues
AHFAQSPHLVLHQLTCQFADGETLFGPLDLTFDQQRCGLVGRNGVGKTRLLRLIAGLDLPGNGHVESHASLAYVAQQPDL
APRTTLAQLLGYGETFAALARLEQGRPQADDIDRLEGQWDLSDRLQAVFTSAGLPPFDPQRPASDLSGGERMRAALCGAM
LGAADFLLLDEPTNHLDTRARDWLYQQLENWRGGLLVASHDRQLLARMQRIVELTPGALHSYGGNYDDYRHQRDLEQQAA
RAGLEHARQERRRTRARQQKEHDISQRRSAQTLKTVDTLNIASFERVAYKAAAKESLGTLRKQHQEQKGSLDAAVREAWQ
RVEEDSPVMLTLPGSTVAAGKQVLVLEQLQLPFITMPPLDLRIDGPMRVALTGPNGCGKTTLLKVILGQLAAKAGRCHCL
LPTAYLDQNLSQLDLSLSVVEHLGLQDSPLNEGRMRSQLAQLQLNAERVLLPLAALSGGERLKAALACMLWRQEPAQLLL
LDEPTNHLDLASSLAIEAALASFPGAMLVVSHDEAFLQALKLTHRLQWRQEGWQLQSL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=527, Percent_Identity=31.1195445920304, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI10947137, Length=512, Percent_Identity=29.1015625, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI27881506, Length=512, Percent_Identity=29.1015625, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI10947135, Length=535, Percent_Identity=30.8411214953271, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI69354671, Length=535, Percent_Identity=30.8411214953271, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1787182, Length=516, Percent_Identity=32.1705426356589, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI2367384, Length=533, Percent_Identity=29.6435272045028, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789751, Length=501, Percent_Identity=30.3393213572854, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787041, Length=538, Percent_Identity=26.2081784386617, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI48994943, Length=231, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081709, Length=244, Percent_Identity=26.6393442622951, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=522, Percent_Identity=29.1187739463602, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17555318, Length=498, Percent_Identity=29.1164658634538, Blast_Score=161, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17553372, Length=535, Percent_Identity=30.2803738317757, Blast_Score=154, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6320874, Length=524, Percent_Identity=26.9083969465649, Blast_Score=148, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6321121, Length=556, Percent_Identity=25.1798561151079, Blast_Score=146, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323278, Length=158, Percent_Identity=32.2784810126582, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324314, Length=166, Percent_Identity=32.5301204819277, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325030, Length=205, Percent_Identity=28.780487804878, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24666836, Length=530, Percent_Identity=30, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24642252, Length=502, Percent_Identity=29.0836653386454, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI18859989, Length=502, Percent_Identity=29.0836653386454, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24641342, Length=554, Percent_Identity=29.0613718411552, Blast_Score=152, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59536; Mature: 59405

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHFAQSPHLVLHQLTCQFADGETLFGPLDLTFDQQRCGLVGRNGVGKTRLLRLIAGLDL
CCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCC
PGNGHVESHASLAYVAQQPDLAPRTTLAQLLGYGETFAALARLEQGRPQADDIDRLEGQW
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCCC
DLSDRLQAVFTSAGLPPFDPQRPASDLSGGERMRAALCGAMLGAADFLLLDEPTNHLDTR
CHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCEEEECCCCCHHHHH
ARDWLYQQLENWRGGLLVASHDRQLLARMQRIVELTPGALHSYGGNYDDYRHQRDLEQQA
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHH
ARAGLEHARQERRRTRARQQKEHDISQRRSAQTLKTVDTLNIASFERVAYKAAAKESLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LRKQHQEQKGSLDAAVREAWQRVEEDSPVMLTLPGSTVAAGKQVLVLEQLQLPFITMPPL
HHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCHHCCCEEEEEHHCCCCEEECCCC
DLRIDGPMRVALTGPNGCGKTTLLKVILGQLAAKAGRCHCLLPTAYLDQNLSQLDLSLSV
CEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCHHHHHHHHHH
VEHLGLQDSPLNEGRMRSQLAQLQLNAERVLLPLAALSGGERLKAALACMLWRQEPAQLL
HHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEE
LLDEPTNHLDLASSLAIEAALASFPGAMLVVSHDEAFLQALKLTHRLQWRQEGWQLQSL
EEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure 
AHFAQSPHLVLHQLTCQFADGETLFGPLDLTFDQQRCGLVGRNGVGKTRLLRLIAGLDL
CCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCC
PGNGHVESHASLAYVAQQPDLAPRTTLAQLLGYGETFAALARLEQGRPQADDIDRLEGQW
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCCC
DLSDRLQAVFTSAGLPPFDPQRPASDLSGGERMRAALCGAMLGAADFLLLDEPTNHLDTR
CHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCEEEECCCCCHHHHH
ARDWLYQQLENWRGGLLVASHDRQLLARMQRIVELTPGALHSYGGNYDDYRHQRDLEQQA
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHH
ARAGLEHARQERRRTRARQQKEHDISQRRSAQTLKTVDTLNIASFERVAYKAAAKESLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LRKQHQEQKGSLDAAVREAWQRVEEDSPVMLTLPGSTVAAGKQVLVLEQLQLPFITMPPL
HHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCHHCCCEEEEEHHCCCCEEECCCC
DLRIDGPMRVALTGPNGCGKTTLLKVILGQLAAKAGRCHCLLPTAYLDQNLSQLDLSLSV
CEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCHHHHHHHHHH
VEHLGLQDSPLNEGRMRSQLAQLQLNAERVLLPLAALSGGERLKAALACMLWRQEPAQLL
HHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEE
LLDEPTNHLDLASSLAIEAALASFPGAMLVVSHDEAFLQALKLTHRLQWRQEGWQLQSL
EEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]