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The map label for this gene is shlB [H]

Identifier: 157372312

GI number: 157372312

Start: 4532462

End: 4534207

Strand: Reverse

Name: shlB [H]

Synonym: Spro_4078

Alternate gene names: 157372312

Gene position: 4534207-4532462 (Counterclockwise)

Preceding gene: 157372319

Following gene: 157372311

Centisome position: 83.21

GC content: 60.14

Gene sequence:

>1746_bases
ATGAAATGGATTTTCATGAAAAGGACCTTTCTTTCGCACGGATCCACATCGAAGGCGTTGAGCCACGTTCTCGCTGGTGT
TCTCTTCACCGGCACTTTCCCGGGTATGGCCGCCACGCCCTCCGATGCCTCGGATCAGGCCGCTTCCGCCATTGATGCCC
GCGAGCAGCAACGCCAGCAGGAGCGCGAGCGCGCTCTGCAACAACAAAATGCACCGCAGGCCGATGCGCGCTTTTCCCGC
CCCCAGGTTGTGCTGCCGGATTACCCGGCCAATGAGTCCCCTTGCTTCGCCATCGAACGGCTCACCTTGGTCGGCGAAAC
GGCCGATCGCTTTCAGTGGGCGCTGGAGGCTGCGGCGGATGCGAGAGGTCGCTGCCTGGGCGGTCAGGGTATCGTGCTTG
CCATCAATAAAGTGCAAAACGCCATACTGGCCAAAGGCTATGTCACCACCCGGGTGATGGCGCAGGAGCAGGACCTGACC
ACGGGGGCGTTGACGCTGACCTTGCAACCGGGTCGTATTGGCGACATTCGCTTTGAGGAGCCAGTCTCCTGGCGTGGACG
GCTGTGGAACGCTATCCCGATCTCACACGGCGATATCCTCAACTTGCGTGATATCGAACAGGGACTGGAGAACTTCAGGC
GAATACCCAGCGCCAGTGCCGACATCAAAATTGTACCCGGTGCTCAGGAGGCCACCAGTGACCTGAAGGTCAACTGGCAC
GAAGGTCGGCCGGTACGGCTTAGTCTGGGACTGGATGACAGCGGCTCCAAGAGTACCGGGCGTTATCTCGGTTCGGCCAC
CCTGGCACTCGATGCCCCCTTTGCGCAGAATGACCTGTTCTACGCCAATATCGGCAAGGATGTGTTCCAGCACGGACCGT
TCGGCAACCGTTCGCATGCACTGAACTACTTTTTCCCGGTGGGTTACTGGGCCTTTTCGGCCAACTACAACGACTACACC
TACCATCAGAACATCCCCAACGCCAATGAGGTACTGCGCTACAGCGGCAAGAGCGACAACATTCAGTTGACCGTTTCCCG
GTTGCTGTACCGCGACCAATCCCACAAGACCACGCTCAACCTGCGCGGCTACCGCAAGCACTCGACTAACCACGTGGATG
ACGTCGAGCTGACCCAGCAAAAACGCCGCACCGCAGGCTGGGAGCTGGGGCTGAACCAGCGCAGCTATTTCGGTACCACC
ACGTTGGATGCCAATATCAGTTGGCGGCGCGGAACCGGGGCGCTGGGTGCCCTGCGCGCACCGGAGGAGGTCAACCACGA
CGGGTCTGCCCGTACAGGTATGTTGCTGGGTGATGCAGCCATCAATATCCCCTTTGCTCTGGGTGAGCAGCCCTGGCGGG
TGTATACCAGCATGCGGGGCCAGTGGAGCCCTAACGCACTAACGCCGCAGGAGCGAATGGCCATTGCCGGGCGTTACACG
GTGCGCGGCTTTGACGGCGAACAGATGCTGTCAGGCGAAAAAGGCCTGCTATGGCGTAATGAAATCGCCTGGAATGTGCT
TTCTCGTGGGCACGAATTGTACCTGGCCGCCGACTACGGTCGGGTGGATGGCCCAGGCACCCGCTACCTGGTGGGTCATC
AGTTGGCGGGCAGTGCGCTCGGTGTGCGCGGCGCACTGTGGGGGCGATTCAGTTACGACCTATTCGCTGGCGTTCCGCTC
TATAAGCCGGCGGGGTTCCATACCTCCGGTGCGACCACGGGTTTTAGCGTAAATCTGGAAATTTGA

Upstream 100 bases:

>100_bases
AGACAAAAGAGGGTTGGAAGCCCCCGCCAAAAACATAATTCACTTGCTTTTTGATCTTGCTGGCGGATAATGCGCCGAAA
ATTACATACCTTTACACTTT

Downstream 100 bases:

>100_bases
ACATCGCGATACCGGCAACGTTGCTGATACTGACCTGATTGGACTGACTTTTCTCACGGATGTGACCCATGAACAAACAT
TGTTATCGCCTTATCTTCAG

Product: polypeptide-transport-associated domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MKWIFMKRTFLSHGSTSKALSHVLAGVLFTGTFPGMAATPSDASDQAASAIDAREQQRQQERERALQQQNAPQADARFSR
PQVVLPDYPANESPCFAIERLTLVGETADRFQWALEAAADARGRCLGGQGIVLAINKVQNAILAKGYVTTRVMAQEQDLT
TGALTLTLQPGRIGDIRFEEPVSWRGRLWNAIPISHGDILNLRDIEQGLENFRRIPSASADIKIVPGAQEATSDLKVNWH
EGRPVRLSLGLDDSGSKSTGRYLGSATLALDAPFAQNDLFYANIGKDVFQHGPFGNRSHALNYFFPVGYWAFSANYNDYT
YHQNIPNANEVLRYSGKSDNIQLTVSRLLYRDQSHKTTLNLRGYRKHSTNHVDDVELTQQKRRTAGWELGLNQRSYFGTT
TLDANISWRRGTGALGALRAPEEVNHDGSARTGMLLGDAAINIPFALGEQPWRVYTSMRGQWSPNALTPQERMAIAGRYT
VRGFDGEQMLSGEKGLLWRNEIAWNVLSRGHELYLAADYGRVDGPGTRYLVGHQLAGSALGVRGALWGRFSYDLFAGVPL
YKPAGFHTSGATTGFSVNLEI

Sequences:

>Translated_581_residues
MKWIFMKRTFLSHGSTSKALSHVLAGVLFTGTFPGMAATPSDASDQAASAIDAREQQRQQERERALQQQNAPQADARFSR
PQVVLPDYPANESPCFAIERLTLVGETADRFQWALEAAADARGRCLGGQGIVLAINKVQNAILAKGYVTTRVMAQEQDLT
TGALTLTLQPGRIGDIRFEEPVSWRGRLWNAIPISHGDILNLRDIEQGLENFRRIPSASADIKIVPGAQEATSDLKVNWH
EGRPVRLSLGLDDSGSKSTGRYLGSATLALDAPFAQNDLFYANIGKDVFQHGPFGNRSHALNYFFPVGYWAFSANYNDYT
YHQNIPNANEVLRYSGKSDNIQLTVSRLLYRDQSHKTTLNLRGYRKHSTNHVDDVELTQQKRRTAGWELGLNQRSYFGTT
TLDANISWRRGTGALGALRAPEEVNHDGSARTGMLLGDAAINIPFALGEQPWRVYTSMRGQWSPNALTPQERMAIAGRYT
VRGFDGEQMLSGEKGLLWRNEIAWNVLSRGHELYLAADYGRVDGPGTRYLVGHQLAGSALGVRGALWGRFSYDLFAGVPL
YKPAGFHTSGATTGFSVNLEI
>Mature_581_residues
MKWIFMKRTFLSHGSTSKALSHVLAGVLFTGTFPGMAATPSDASDQAASAIDAREQQRQQERERALQQQNAPQADARFSR
PQVVLPDYPANESPCFAIERLTLVGETADRFQWALEAAADARGRCLGGQGIVLAINKVQNAILAKGYVTTRVMAQEQDLT
TGALTLTLQPGRIGDIRFEEPVSWRGRLWNAIPISHGDILNLRDIEQGLENFRRIPSASADIKIVPGAQEATSDLKVNWH
EGRPVRLSLGLDDSGSKSTGRYLGSATLALDAPFAQNDLFYANIGKDVFQHGPFGNRSHALNYFFPVGYWAFSANYNDYT
YHQNIPNANEVLRYSGKSDNIQLTVSRLLYRDQSHKTTLNLRGYRKHSTNHVDDVELTQQKRRTAGWELGLNQRSYFGTT
TLDANISWRRGTGALGALRAPEEVNHDGSARTGMLLGDAAINIPFALGEQPWRVYTSMRGQWSPNALTPQERMAIAGRYT
VRGFDGEQMLSGEKGLLWRNEIAWNVLSRGHELYLAADYGRVDGPGTRYLVGHQLAGSALGVRGALWGRFSYDLFAGVPL
YKPAGFHTSGATTGFSVNLEI

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 64179; Mature: 64179

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWIFMKRTFLSHGSTSKALSHVLAGVLFTGTFPGMAATPSDASDQAASAIDAREQQRQQ
CCEEEEEHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERERALQQQNAPQADARFSRPQVVLPDYPANESPCFAIERLTLVGETADRFQWALEAAAD
HHHHHHHHCCCCCCCHHCCCCEEECCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCC
ARGRCLGGQGIVLAINKVQNAILAKGYVTTRVMAQEQDLTTGALTLTLQPGRIGDIRFEE
CCCEEECCCCEEEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCCCEEECC
PVSWRGRLWNAIPISHGDILNLRDIEQGLENFRRIPSASADIKIVPGAQEATSDLKVNWH
CCCCCCCEEEEEECCCCCEECHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEC
EGRPVRLSLGLDDSGSKSTGRYLGSATLALDAPFAQNDLFYANIGKDVFQHGPFGNRSHA
CCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCHHHHHCCCCCCCCCE
LNYFFPVGYWAFSANYNDYTYHQNIPNANEVLRYSGKSDNIQLTVSRLLYRDQSHKTTLN
EEEEEEEEEEEEECCCCCEEEECCCCCHHHHHEECCCCCCEEEEEHHHHHCCCCCCEEEE
LRGYRKHSTNHVDDVELTQQKRRTAGWELGLNQRSYFGTTTLDANISWRRGTGALGALRA
ECCEECCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCEEEEECCEEEECCCCCCCCCCC
PEEVNHDGSARTGMLLGDAAINIPFALGEQPWRVYTSMRGQWSPNALTPQERMAIAGRYT
CHHCCCCCCCCCCEEEECCEEECCCCCCCCCEEEHECCCCCCCCCCCCHHHHHEEEEEEE
VRGFDGEQMLSGEKGLLWRNEIAWNVLSRGHELYLAADYGRVDGPGTRYLVGHQLAGSAL
EECCCCHHHHCCCCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCCCC
GVRGALWGRFSYDLFAGVPLYKPAGFHTSGATTGFSVNLEI
CCCHHEECCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKWIFMKRTFLSHGSTSKALSHVLAGVLFTGTFPGMAATPSDASDQAASAIDAREQQRQQ
CCEEEEEHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERERALQQQNAPQADARFSRPQVVLPDYPANESPCFAIERLTLVGETADRFQWALEAAAD
HHHHHHHHCCCCCCCHHCCCCEEECCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCC
ARGRCLGGQGIVLAINKVQNAILAKGYVTTRVMAQEQDLTTGALTLTLQPGRIGDIRFEE
CCCEEECCCCEEEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCCCEEECC
PVSWRGRLWNAIPISHGDILNLRDIEQGLENFRRIPSASADIKIVPGAQEATSDLKVNWH
CCCCCCCEEEEEECCCCCEECHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEC
EGRPVRLSLGLDDSGSKSTGRYLGSATLALDAPFAQNDLFYANIGKDVFQHGPFGNRSHA
CCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCHHHHHCCCCCCCCCE
LNYFFPVGYWAFSANYNDYTYHQNIPNANEVLRYSGKSDNIQLTVSRLLYRDQSHKTTLN
EEEEEEEEEEEEECCCCCEEEECCCCCHHHHHEECCCCCCEEEEEHHHHHCCCCCCEEEE
LRGYRKHSTNHVDDVELTQQKRRTAGWELGLNQRSYFGTTTLDANISWRRGTGALGALRA
ECCEECCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCEEEEECCEEEECCCCCCCCCCC
PEEVNHDGSARTGMLLGDAAINIPFALGEQPWRVYTSMRGQWSPNALTPQERMAIAGRYT
CHHCCCCCCCCCCEEEECCEEECCCCCCCCCEEEHECCCCCCCCCCCCHHHHHEEEEEEE
VRGFDGEQMLSGEKGLLWRNEIAWNVLSRGHELYLAADYGRVDGPGTRYLVGHQLAGSAL
EECCCCHHHHCCCCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCCCC
GVRGALWGRFSYDLFAGVPLYKPAGFHTSGATTGFSVNLEI
CCCHHEECCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]