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The map label for this gene is creB [H]

Identifier: 157372130

GI number: 157372130

Start: 4317279

End: 4317974

Strand: Reverse

Name: creB [H]

Synonym: Spro_3896

Alternate gene names: 157372130

Gene position: 4317974-4317279 (Counterclockwise)

Preceding gene: 157372131

Following gene: 157372129

Centisome position: 79.25

GC content: 58.62

Gene sequence:

>696_bases
ATGAAGCCGACGCTCTGGCTGGTGGAAGATGAACCCAGCATTGCCGACACGCTGATTTATACCCTGGAAAGCGAAGGCTT
TCAGGTGCGCTGGTTCGAACGCGGTGAACCGGCATTACAGGCGTTGGCGCAAGGGGCACCTGCGCTGGCGATCCTCGATG
TTGGTCTGCCGGACATCAATGGTTTTGAACTCTGCCGCCGGTTGTTATCGCAGTCGGCGGATTTGCCTATTTTATTTCTC
ACCGCCCGCAGCGATGAGCTTGATCGCCTGATAGGGTTGGAAATCGGTGCCGATGATTACGTCGCCAAACCCTTTTCCCC
GCGAGAAGTCAGCGCCCGGGTGCGCACTATTCTGCGCCGTTTGCAAAAACAGCAGCGCCTGCAGCAGCCGGCTCTGTATC
AATTCGGCCCTTTCAGCCTGGACGAACAGGCCGCGGCCATCCATTACCATCAGCAGCCGCTGCTGCTGACCCGTTACGAA
TTTTTGCTGTTGAAAACGCTGTTGCTGGCGCCCGGCCGGGTATTTTCACGCCAGCAACTGATGGAAAGTGTCTGGGCGCT
GGCCGAAGAAAGCCTGGATCGCACCGTCGACACCCATATCAAAACGTTGCGTGCCAAGCTGCGCGCCATCGATCCCGCTG
AACCCCCGATCCACACTCATCGCGGCCTCGGCTACAGCGTGAGCCGCCAGCCATGA

Upstream 100 bases:

>100_bases
GTCGGCTGTGGCTGGCTTCCGACTCTATGGCTAAAGCCGACTGGCGGCAGTTGCGCCAACGGTTGCTGTATCCGCCCGCC
AGTGATGACGAGGAGCCCTG

Downstream 100 bases:

>100_bases
GAATAGGCCTGCGCCTGCTGTTGGGGTACTTCCTGATTGTGGCGGTGGCGGGCTATTTCGTACTGAGCATTTTCGTGCAG
GAAGTGAAACCCGGCGTGCG

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKPTLWLVEDEPSIADTLIYTLESEGFQVRWFERGEPALQALAQGAPALAILDVGLPDINGFELCRRLLSQSADLPILFL
TARSDELDRLIGLEIGADDYVAKPFSPREVSARVRTILRRLQKQQRLQQPALYQFGPFSLDEQAAAIHYHQQPLLLTRYE
FLLLKTLLLAPGRVFSRQQLMESVWALAEESLDRTVDTHIKTLRAKLRAIDPAEPPIHTHRGLGYSVSRQP

Sequences:

>Translated_231_residues
MKPTLWLVEDEPSIADTLIYTLESEGFQVRWFERGEPALQALAQGAPALAILDVGLPDINGFELCRRLLSQSADLPILFL
TARSDELDRLIGLEIGADDYVAKPFSPREVSARVRTILRRLQKQQRLQQPALYQFGPFSLDEQAAAIHYHQQPLLLTRYE
FLLLKTLLLAPGRVFSRQQLMESVWALAEESLDRTVDTHIKTLRAKLRAIDPAEPPIHTHRGLGYSVSRQP
>Mature_231_residues
MKPTLWLVEDEPSIADTLIYTLESEGFQVRWFERGEPALQALAQGAPALAILDVGLPDINGFELCRRLLSQSADLPILFL
TARSDELDRLIGLEIGADDYVAKPFSPREVSARVRTILRRLQKQQRLQQPALYQFGPFSLDEQAAAIHYHQQPLLLTRYE
FLLLKTLLLAPGRVFSRQQLMESVWALAEESLDRTVDTHIKTLRAKLRAIDPAEPPIHTHRGLGYSVSRQP

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=65.1982378854625, Blast_Score=290, Evalue=6e-80,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=43.0493273542601, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=38.2222222222222, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=36.6379310344828, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=33.7719298245614, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=34.9344978165939, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=37.219730941704, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=35.5855855855856, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=33.4821428571429, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=32.579185520362, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=35.7466063348416, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=38.2222222222222, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=32.579185520362, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=29.6137339055794, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=31.9672131147541, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26190; Mature: 26190

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTLWLVEDEPSIADTLIYTLESEGFQVRWFERGEPALQALAQGAPALAILDVGLPDIN
CCCCEEEEECCCCHHHHHHHEECCCCCEEEEEECCCHHHHHHHCCCCEEEEEECCCCCCC
GFELCRRLLSQSADLPILFLTARSDELDRLIGLEIGADDYVAKPFSPREVSARVRTILRR
HHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCEECCCCCCCCCCCCHHHHHHHHHHHHH
LQKQQRLQQPALYQFGPFSLDEQAAAIHYHQQPLLLTRYEFLLLKTLLLAPGRVFSRQQL
HHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
MESVWALAEESLDRTVDTHIKTLRAKLRAIDPAEPPIHTHRGLGYSVSRQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKPTLWLVEDEPSIADTLIYTLESEGFQVRWFERGEPALQALAQGAPALAILDVGLPDIN
CCCCEEEEECCCCHHHHHHHEECCCCCEEEEEECCCHHHHHHHCCCCEEEEEECCCCCCC
GFELCRRLLSQSADLPILFLTARSDELDRLIGLEIGADDYVAKPFSPREVSARVRTILRR
HHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCEECCCCCCCCCCCCHHHHHHHHHHHHH
LQKQQRLQQPALYQFGPFSLDEQAAAIHYHQQPLLLTRYEFLLLKTLLLAPGRVFSRQQL
HHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
MESVWALAEESLDRTVDTHIKTLRAKLRAIDPAEPPIHTHRGLGYSVSRQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]