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The map label for this gene is slt [C]

Identifier: 157372112

GI number: 157372112

Start: 4292220

End: 4294916

Strand: Reverse

Name: slt [C]

Synonym: Spro_3877

Alternate gene names: 157372112

Gene position: 4294916-4292220 (Counterclockwise)

Preceding gene: 157372113

Following gene: 157372111

Centisome position: 78.82

GC content: 48.24

Gene sequence:

>2697_bases
ATGCCAATCGTCCCAACGTATCAGCGTCAGTCTCAATCGCAGATGGCACCGGTTAACACTCAGGATTTGAGGATCCCGAA
AGATAGCGCCTTCACTGCGCTGGCAGATGTAGGCGCGAAAGGGCTGGAGGTGTACCAGCAGGAGCGGCAAAAGGTCGATT
TGGCTGATATGCAGGACAAACTCAATCAGTTTTCCCAGTATGCCGATGACTTGTACAACAACCCGCAGAATGGCCTGATC
ACGTTGCAGGGAAAAAACGCTATCGGCCAAGGTGAAGCACGAGCTGGTCAGATATCAAATAAAGCAGCTGAGATACGTGA
ATCTTTGCCCGAGTACATGCGCCCGGCGTTTGATCAACAGATCCAGCCGCTTGGCCGTAGTTATGGCAATAAATTTCGCC
AGTATGATATTGGGCAGAAGCAACAGTATGAAGCTGGCCAACAGCAAGGCGTATTGAGTAATTTTTTAACTCAGGCTAAT
GATCCTACACAGTTTCAGCCAGCGGTGCTTTCTGCTCGACAGGCGATAATGGATTATGGTGCTACTCATGGTCAGAGTCC
GGAAGAGATAGAGGCAAATTGGCAGCAATGGTATCAAGGAGCAGCTAATTCAGCATTTAGCACTGCCTATACCAATATGT
ATCAGCAGACCATGGGGCCGGATGGGGTAATTCCTGTAACGGATGGTGCAAATAGCGATCAATTATTCTCTGCAATGATT
CGAGCAGAAAGTGGAGGCAACCAATTCGATAGTACTGGCTCGCCGCTTATGTCCTCAAAAGGAGCTGCTGGGATTGCTCA
GGTAACAGAATCAACAGGACCCGAGGCTGCTCAGCTTGCTGGCTTGTCGTGGGATAGGGATAAGTGGCTGAATGACCCAC
GCTACAACGCGACTATTGGGCATGCCTATTTTCAGTCACAGATGAAACGTTATGACGGAGATTCAGTGCTCGCTGTTGCC
GCATATAATGCAGGTCAAGGTCAGGTTAACAAATGGATCGCGCAACTTGGTGATCCGCGCAAAGGTGAGATTTCATCTGC
TGAATTCGTAGCCAAAATACCATTTGAAGAAACACGGAACTATGTATCAAAAGTAGTTGGTTCTGCCCCAGGAATTCCGG
TCAACGCTTCTATTACTGGATTGATGAATACGCCATATTGGCAGGCTATGAGCCCTCAGAACAAATCAGCCGCAATGGCT
AAAATTGCTGGGCTGTACGACCTTCAAAATTCAGCAGCACGTTTGAGTTTACAGAATAGAATGCAGGACGATGAAACGCG
TGTTGAGCTTGGTCAGCCAGTGTCTGCACCAATTACAGAGCGAGAGTGGGTTTCCTCGATGCCGCTCAGTGCCACGCCGC
AAGAGCGAATGCAATTACAGCAGTCATACCAACGCTACCAGCAAACCCTTGCTATGCAGGCAGCCTATCAAACGATTGTG
CAAGGTGATGTACAGCAGGGCATGGCGGCAGTAAATGCTATGAAGCCAGATGTTAGCGATCCCGACTTTACGTTCAAACA
GCAGCGATATGCGCAAGTGGCCAGTAAATATTCTCAAGTGCAGAAAGCCAGGGAAGATGACCCGGGCACATGGCTTCTTC
AGAACTCTCCAGTTATCAAGGATGCCTATAACCAATTTTCTCAACGGCAGGTATCCGGCGAATACTTTGCCTCGCGTATT
CGGGCTGAGAAAGAGCGGCTGGGGATCCGTAGCAAAGACATACTTCCGGCCGAGATGGTTAATAGTGTTCTGCACCAGAT
CGATAGTAGCAATGAGCAAAGCGTGGCGGCCGTACAAGCTATTGCCCAGAGCTATGGGAGCCAAGCACCGGCTGTAATCG
CGCAATTGCAGGGGAAATCGGGAAGTGCACTCAGTGTTGTCATGTCTGTTGATAATGCCAATGCAGCTAATGCATTGTTC
CAAAACAGAAAGCTATCAACAGATGAATTAAAAAAGGCGTCTGGCACACAATCATCATCTGTTGAAAGCGAATGGTCGGA
TCAGTTTGCTGATTTTGGTGTGTCACTGGCATCTCAAAGGGGTGGACTAAAGGCATATTCAGACTTCAATGAGCAAGGAA
AGCGTCTTGCATACATCTATGCATCGCGCGGCATGGATGGGGCGTCTGCTGCCAAGATGGCATTCAATCAGATTGCTGGC
GACCAATACGACTTTGAAGGCGCTTGGCGCCTGCCAAAATCATTAAACCTAAATGTTCGAGACATTACTGACGGAACAAA
GAACTACCTGGAAAAACTAAAGCCAGAAGATATAGATCCGCAAGGTTTTGTGGGTGACTCTCGCTTACCCGCCGATGTTG
GCAGAGCAATGGCGTTGTCCAGAATAAAAAACAATGCTGAATGGGTTACAAGTGAAGACGAAAAAGGGCTTTACCTCACA
GCAGATCGAACCTATATCAACGGGGCTGATGGCAATCCAATATTTGTCCCATTCAAGGAACTTTCTCAGCTTGGAATTGC
AGACAGAAGTTTCATTAATGCACGGCTCCATGAATTAAAAACCCCGGCAACTTTCACCCCTGCTGACGGAATGGATAATC
GAACTATCAATAATGATTTGTCAGATGTCTACCGTAGCCTGCGTGGCGAACCTGCGAGAGAGTTTACTGGCTACCAGGAA
CAGAATCCTGCGGAAAACACACTGGGTAATGCTCTTCAGCACAGGAGTGGTCAATGA

Upstream 100 bases:

>100_bases
CAGGAGCGCAGTAAATCCCCCCTTGGTGTTGCGCCATCCCTCCAAGACATCGCCCGCGGCCTCATCCGCAAAGCATTGCA
ACAAGTAGGAGAGTAGTTCC

Downstream 100 bases:

>100_bases
CAATCTATACAACAAAGCCTGATTCATCAGTTACCAGGCCACTTACAAATTTAGAATCAGGACTTGGTGAAAGTCTATCG
GCTGAATTTACCGAAGGATT

Product: lytic transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: Soluble Lytic Murein Transglycosylase; Soluble Lytic Transglycosylase; Transglycosylase Slt Family; Lytic Transglycosylase; Slt Family Transglycosylase; Transglycosylase; Murein Transglycosylase Protein; Transglycosylase SLT Domain Protein; Lytic Murein Transglycosylase; Soluble Lytic Transglycosylase Domain-Containing Protein; Lytic Murein Transglycosylase Family Protein; Lytic Transglycosylase Domain-Containing Protein; MltE Protein; Secreted Protein

Number of amino acids: Translated: 898; Mature: 897

Protein sequence:

>898_residues
MPIVPTYQRQSQSQMAPVNTQDLRIPKDSAFTALADVGAKGLEVYQQERQKVDLADMQDKLNQFSQYADDLYNNPQNGLI
TLQGKNAIGQGEARAGQISNKAAEIRESLPEYMRPAFDQQIQPLGRSYGNKFRQYDIGQKQQYEAGQQQGVLSNFLTQAN
DPTQFQPAVLSARQAIMDYGATHGQSPEEIEANWQQWYQGAANSAFSTAYTNMYQQTMGPDGVIPVTDGANSDQLFSAMI
RAESGGNQFDSTGSPLMSSKGAAGIAQVTESTGPEAAQLAGLSWDRDKWLNDPRYNATIGHAYFQSQMKRYDGDSVLAVA
AYNAGQGQVNKWIAQLGDPRKGEISSAEFVAKIPFEETRNYVSKVVGSAPGIPVNASITGLMNTPYWQAMSPQNKSAAMA
KIAGLYDLQNSAARLSLQNRMQDDETRVELGQPVSAPITEREWVSSMPLSATPQERMQLQQSYQRYQQTLAMQAAYQTIV
QGDVQQGMAAVNAMKPDVSDPDFTFKQQRYAQVASKYSQVQKAREDDPGTWLLQNSPVIKDAYNQFSQRQVSGEYFASRI
RAEKERLGIRSKDILPAEMVNSVLHQIDSSNEQSVAAVQAIAQSYGSQAPAVIAQLQGKSGSALSVVMSVDNANAANALF
QNRKLSTDELKKASGTQSSSVESEWSDQFADFGVSLASQRGGLKAYSDFNEQGKRLAYIYASRGMDGASAAKMAFNQIAG
DQYDFEGAWRLPKSLNLNVRDITDGTKNYLEKLKPEDIDPQGFVGDSRLPADVGRAMALSRIKNNAEWVTSEDEKGLYLT
ADRTYINGADGNPIFVPFKELSQLGIADRSFINARLHELKTPATFTPADGMDNRTINNDLSDVYRSLRGEPAREFTGYQE
QNPAENTLGNALQHRSGQ

Sequences:

>Translated_898_residues
MPIVPTYQRQSQSQMAPVNTQDLRIPKDSAFTALADVGAKGLEVYQQERQKVDLADMQDKLNQFSQYADDLYNNPQNGLI
TLQGKNAIGQGEARAGQISNKAAEIRESLPEYMRPAFDQQIQPLGRSYGNKFRQYDIGQKQQYEAGQQQGVLSNFLTQAN
DPTQFQPAVLSARQAIMDYGATHGQSPEEIEANWQQWYQGAANSAFSTAYTNMYQQTMGPDGVIPVTDGANSDQLFSAMI
RAESGGNQFDSTGSPLMSSKGAAGIAQVTESTGPEAAQLAGLSWDRDKWLNDPRYNATIGHAYFQSQMKRYDGDSVLAVA
AYNAGQGQVNKWIAQLGDPRKGEISSAEFVAKIPFEETRNYVSKVVGSAPGIPVNASITGLMNTPYWQAMSPQNKSAAMA
KIAGLYDLQNSAARLSLQNRMQDDETRVELGQPVSAPITEREWVSSMPLSATPQERMQLQQSYQRYQQTLAMQAAYQTIV
QGDVQQGMAAVNAMKPDVSDPDFTFKQQRYAQVASKYSQVQKAREDDPGTWLLQNSPVIKDAYNQFSQRQVSGEYFASRI
RAEKERLGIRSKDILPAEMVNSVLHQIDSSNEQSVAAVQAIAQSYGSQAPAVIAQLQGKSGSALSVVMSVDNANAANALF
QNRKLSTDELKKASGTQSSSVESEWSDQFADFGVSLASQRGGLKAYSDFNEQGKRLAYIYASRGMDGASAAKMAFNQIAG
DQYDFEGAWRLPKSLNLNVRDITDGTKNYLEKLKPEDIDPQGFVGDSRLPADVGRAMALSRIKNNAEWVTSEDEKGLYLT
ADRTYINGADGNPIFVPFKELSQLGIADRSFINARLHELKTPATFTPADGMDNRTINNDLSDVYRSLRGEPAREFTGYQE
QNPAENTLGNALQHRSGQ
>Mature_897_residues
PIVPTYQRQSQSQMAPVNTQDLRIPKDSAFTALADVGAKGLEVYQQERQKVDLADMQDKLNQFSQYADDLYNNPQNGLIT
LQGKNAIGQGEARAGQISNKAAEIRESLPEYMRPAFDQQIQPLGRSYGNKFRQYDIGQKQQYEAGQQQGVLSNFLTQAND
PTQFQPAVLSARQAIMDYGATHGQSPEEIEANWQQWYQGAANSAFSTAYTNMYQQTMGPDGVIPVTDGANSDQLFSAMIR
AESGGNQFDSTGSPLMSSKGAAGIAQVTESTGPEAAQLAGLSWDRDKWLNDPRYNATIGHAYFQSQMKRYDGDSVLAVAA
YNAGQGQVNKWIAQLGDPRKGEISSAEFVAKIPFEETRNYVSKVVGSAPGIPVNASITGLMNTPYWQAMSPQNKSAAMAK
IAGLYDLQNSAARLSLQNRMQDDETRVELGQPVSAPITEREWVSSMPLSATPQERMQLQQSYQRYQQTLAMQAAYQTIVQ
GDVQQGMAAVNAMKPDVSDPDFTFKQQRYAQVASKYSQVQKAREDDPGTWLLQNSPVIKDAYNQFSQRQVSGEYFASRIR
AEKERLGIRSKDILPAEMVNSVLHQIDSSNEQSVAAVQAIAQSYGSQAPAVIAQLQGKSGSALSVVMSVDNANAANALFQ
NRKLSTDELKKASGTQSSSVESEWSDQFADFGVSLASQRGGLKAYSDFNEQGKRLAYIYASRGMDGASAAKMAFNQIAGD
QYDFEGAWRLPKSLNLNVRDITDGTKNYLEKLKPEDIDPQGFVGDSRLPADVGRAMALSRIKNNAEWVTSEDEKGLYLTA
DRTYINGADGNPIFVPFKELSQLGIADRSFINARLHELKTPATFTPADGMDNRTINNDLSDVYRSLRGEPAREFTGYQEQ
NPAENTLGNALQHRSGQ

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082441, Length=164, Percent_Identity=30.4878048780488, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 98722; Mature: 98591

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIVPTYQRQSQSQMAPVNTQDLRIPKDSAFTALADVGAKGLEVYQQERQKVDLADMQDK
CCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHH
LNQFSQYADDLYNNPQNGLITLQGKNAIGQGEARAGQISNKAAEIRESLPEYMRPAFDQQ
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IQPLGRSYGNKFRQYDIGQKQQYEAGQQQGVLSNFLTQANDPTQFQPAVLSARQAIMDYG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
ATHGQSPEEIEANWQQWYQGAANSAFSTAYTNMYQQTMGPDGVIPVTDGANSDQLFSAMI
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHH
RAESGGNQFDSTGSPLMSSKGAAGIAQVTESTGPEAAQLAGLSWDRDKWLNDPRYNATIG
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCCHHHHCCCCCCCCHHH
HAYFQSQMKRYDGDSVLAVAAYNAGQGQVNKWIAQLGDPRKGEISSAEFVAKIPFEETRN
HHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHEEECCHHHHHH
YVSKVVGSAPGIPVNASITGLMNTPYWQAMSPQNKSAAMAKIAGLYDLQNSAARLSLQNR
HHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
MQDDETRVELGQPVSAPITEREWVSSMPLSATPQERMQLQQSYQRYQQTLAMQAAYQTIV
CCCCHHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGDVQQGMAAVNAMKPDVSDPDFTFKQQRYAQVASKYSQVQKAREDDPGTWLLQNSPVIK
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHH
DAYNQFSQRQVSGEYFASRIRAEKERLGIRSKDILPAEMVNSVLHQIDSSNEQSVAAVQA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
IAQSYGSQAPAVIAQLQGKSGSALSVVMSVDNANAANALFQNRKLSTDELKKASGTQSSS
HHHHHCCCCCHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCCHHHHHHHCCCCCCC
VESEWSDQFADFGVSLASQRGGLKAYSDFNEQGKRLAYIYASRGMDGASAAKMAFNQIAG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCC
DQYDFEGAWRLPKSLNLNVRDITDGTKNYLEKLKPEDIDPQGFVGDSRLPADVGRAMALS
CCCCCCCHHCCCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RIKNNAEWVTSEDEKGLYLTADRTYINGADGNPIFVPFKELSQLGIADRSFINARLHELK
HHHCCCCCCCCCCCCCEEEEECCEEEECCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHC
TPATFTPADGMDNRTINNDLSDVYRSLRGEPAREFTGYQEQNPAENTLGNALQHRSGQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PIVPTYQRQSQSQMAPVNTQDLRIPKDSAFTALADVGAKGLEVYQQERQKVDLADMQDK
CCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHH
LNQFSQYADDLYNNPQNGLITLQGKNAIGQGEARAGQISNKAAEIRESLPEYMRPAFDQQ
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IQPLGRSYGNKFRQYDIGQKQQYEAGQQQGVLSNFLTQANDPTQFQPAVLSARQAIMDYG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
ATHGQSPEEIEANWQQWYQGAANSAFSTAYTNMYQQTMGPDGVIPVTDGANSDQLFSAMI
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHH
RAESGGNQFDSTGSPLMSSKGAAGIAQVTESTGPEAAQLAGLSWDRDKWLNDPRYNATIG
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCCHHHHCCCCCCCCHHH
HAYFQSQMKRYDGDSVLAVAAYNAGQGQVNKWIAQLGDPRKGEISSAEFVAKIPFEETRN
HHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHEEECCHHHHHH
YVSKVVGSAPGIPVNASITGLMNTPYWQAMSPQNKSAAMAKIAGLYDLQNSAARLSLQNR
HHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
MQDDETRVELGQPVSAPITEREWVSSMPLSATPQERMQLQQSYQRYQQTLAMQAAYQTIV
CCCCHHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGDVQQGMAAVNAMKPDVSDPDFTFKQQRYAQVASKYSQVQKAREDDPGTWLLQNSPVIK
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHH
DAYNQFSQRQVSGEYFASRIRAEKERLGIRSKDILPAEMVNSVLHQIDSSNEQSVAAVQA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
IAQSYGSQAPAVIAQLQGKSGSALSVVMSVDNANAANALFQNRKLSTDELKKASGTQSSS
HHHHHCCCCCHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCCHHHHHHHCCCCCCC
VESEWSDQFADFGVSLASQRGGLKAYSDFNEQGKRLAYIYASRGMDGASAAKMAFNQIAG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCC
DQYDFEGAWRLPKSLNLNVRDITDGTKNYLEKLKPEDIDPQGFVGDSRLPADVGRAMALS
CCCCCCCHHCCCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RIKNNAEWVTSEDEKGLYLTADRTYINGADGNPIFVPFKELSQLGIADRSFINARLHELK
HHHCCCCCCCCCCCCCEEEEECCEEEECCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHC
TPATFTPADGMDNRTINNDLSDVYRSLRGEPAREFTGYQEQNPAENTLGNALQHRSGQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA