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The map label for this gene is lgt

Identifier: 157372057

GI number: 157372057

Start: 4228818

End: 4229690

Strand: Reverse

Name: lgt

Synonym: Spro_3822

Alternate gene names: 157372057

Gene position: 4229690-4228818 (Counterclockwise)

Preceding gene: 157372058

Following gene: 157372056

Centisome position: 77.63

GC content: 56.24

Gene sequence:

>873_bases
ATGACCAATAGCTATCTGGCGTTTCCTAAATTTGATCCGGTGATTTTCTCGATCGGCCCGGTTTCTCTGCATTGGTACGG
TCTGATGTACCTGGTTGGCTTTGTTTTTGCCATGTGGCTGGCGGTACGCCGGGCTAACAAACCAGGCAGCGGCTGGACCA
AGGATGAAGTAGAGAACCTGCTGTACGCCGGTTTCCTCGGTGTGTTCGTCGGTGGCCGCGTGGGCTATGTGCTGTTCTAC
AACCTGCCGCTGTTCATGGAAAACCCGCTCTATCTGTTTAAAGTCTGGGATGGCGGTATGTCGTTCCACGGCGGTTTGAT
GGGGGTGATCCTGGTGATGTTCTGGTTCGCTCGCCGCACCAAACGCACCTTCTTCCAGGTTTCTGATTTTATTGCCCCGT
TGATCCCCTTCGGCCTGGGCGCCGGCCGTTTGGGCAACTTTATCAATGGTGAACTCTGGGGCCGCGTGACTACCGATACC
CCATGGGCGATGCTGTTCCCAAGCTCGCGTGCAGAAGACGTGGCGCTTGCCGCCGCCGATCCGAAACTGTTGCCTATCCT
GAACCAATACGGCGTGTTGCCGCGTCACCCGTCCCAGCTGTATGAACTGCTGTTGGAAGGCGTGGTGCTGTTTATCATTC
TGAACCTATTTATCCGCAAGCCGCGGCCGATGGGTGCCGTCTCCGGCCTGTTCCTGATTGGCTATGGTGCATTCCGTATT
ATTGTCGAAGCTTTCCGCCAGCCGGATGCCCAACTCGGCCTGTTCGACGGCGTAATCAGCATGGGGCAGATCCTGTCCGT
CCCTATGGTGGTGGCCGGTATTATTATGATGATTTGGGCGTATCGTCGCCGCCCGCAGCAACAACTGTCGTGA

Upstream 100 bases:

>100_bases
GTTGAAAGCCACGGAAAAATAGTGTTCCCGCTGTGTTTCACCGCGTTTGGCACCTGCCGCCCCCGGATGGGGAAGAATAA
TAGACATGTTGTGGTGATAG

Downstream 100 bases:

>100_bases
GGAACAAATGAAACAGTATCTGGATTTGATGAACAAAGTGCTCGCCGAGGGCACCCCTAAAGCCGACCGTACCGGCACTG
GCACCTTGTCGATATTCGGC

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTNSYLAFPKFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKDEVENLLYAGFLGVFVGGRVGYVLFY
NLPLFMENPLYLFKVWDGGMSFHGGLMGVILVMFWFARRTKRTFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVTTDT
PWAMLFPSSRAEDVALAAADPKLLPILNQYGVLPRHPSQLYELLLEGVVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRI
IVEAFRQPDAQLGLFDGVISMGQILSVPMVVAGIIMMIWAYRRRPQQQLS

Sequences:

>Translated_290_residues
MTNSYLAFPKFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKDEVENLLYAGFLGVFVGGRVGYVLFY
NLPLFMENPLYLFKVWDGGMSFHGGLMGVILVMFWFARRTKRTFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVTTDT
PWAMLFPSSRAEDVALAAADPKLLPILNQYGVLPRHPSQLYELLLEGVVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRI
IVEAFRQPDAQLGLFDGVISMGQILSVPMVVAGIIMMIWAYRRRPQQQLS
>Mature_289_residues
TNSYLAFPKFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKDEVENLLYAGFLGVFVGGRVGYVLFYN
LPLFMENPLYLFKVWDGGMSFHGGLMGVILVMFWFARRTKRTFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVTTDTP
WAMLFPSSRAEDVALAAADPKLLPILNQYGVLPRHPSQLYELLLEGVVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRII
VEAFRQPDAQLGLFDGVISMGQILSVPMVVAGIIMMIWAYRRRPQQQLS

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=291, Percent_Identity=80.7560137457045, Blast_Score=476, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_SERP5 (A8GIH8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480046.1
- STRING:   A8GIH8
- GeneID:   5606800
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3822
- eggNOG:   COG0682
- HOGENOM:   HBG450278
- OMA:   RIGPLAI
- ProtClustDB:   PRK00052
- BioCyc:   SPRO399741:SPRO_3822-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 32591; Mature: 32460

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1078bff8)-; HASH(0xedc1a8c)-; HASH(0xed9a034)-; HASH(0xedc1e1c)-; HASH(0x118550bc)-; HASH(0x102c7be8)-; HASH(0x10784294)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSYLAFPKFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKDEVENL
CCCCEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LYAGFLGVFVGGRVGYVLFYNLPLFMENPLYLFKVWDGGMSFHGGLMGVILVMFWFARRT
HHHHHHHHHHCCHHEEEEEEECCCEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
KRTFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVTTDTPWAMLFPSSRAEDVALAAAD
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCEEEECCC
PKLLPILNQYGVLPRHPSQLYELLLEGVVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRI
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IVEAFRQPDAQLGLFDGVISMGQILSVPMVVAGIIMMIWAYRRRPQQQLS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCH
>Mature Secondary Structure 
TNSYLAFPKFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKDEVENL
CCCEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LYAGFLGVFVGGRVGYVLFYNLPLFMENPLYLFKVWDGGMSFHGGLMGVILVMFWFARRT
HHHHHHHHHHCCHHEEEEEEECCCEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
KRTFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVTTDTPWAMLFPSSRAEDVALAAAD
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCEEEECCC
PKLLPILNQYGVLPRHPSQLYELLLEGVVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRI
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IVEAFRQPDAQLGLFDGVISMGQILSVPMVVAGIIMMIWAYRRRPQQQLS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA