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The map label for this gene is cysW [H]

Identifier: 157371692

GI number: 157371692

Start: 3826505

End: 3827380

Strand: Reverse

Name: cysW [H]

Synonym: Spro_3455

Alternate gene names: 157371692

Gene position: 3827380-3826505 (Counterclockwise)

Preceding gene: 157371693

Following gene: 157371691

Centisome position: 70.24

GC content: 57.53

Gene sequence:

>876_bases
ATGGCGGATATCTCTGAGTTCAACGGCGTCGAACGCCCGCGCGTCAACTGGGGCAAGTGGACGCTGATCGGTATCGGCGT
GCTGTTTTCGGTACTGCTGCTGGTAGTGCCGATCGTTTCGATTTTCGCCGAGGCCTTTTCCAAAGGTATTGGTGCGATGT
GGGGCAACCTGGTCGATCACGACATGTTGCACGCTATCTGGCTGACGGTGCTGATCGCCTTGATTACCGTGCCGTTCAAC
CTGATTTTCGGCACGCTGTTGGCCTGGCTGGTGACGCGTTTTACCTTTCCGGGGCGTCAACTGTTACTGACGTTGATCGA
CATCCCGTTCGCCGTTTCGCCGGTGGTAGCGGGGCTGATTTACCTGTTGTTCTACGGCAGCAATGGCCTGCTGGGCGGTT
GGCTGGATGCGCATAATATCCAGCTGATGTTCTCCTGGCCGGGCATGGTGCTGGTGACCATTTTCGTGACCTGTCCGTTC
GTGGTACGTGAGCTGGTGCCGATGATGTTCAGCCAGGGCAGTCAGGAAGACGAGGCCGCCATTTTGCTGGGGGCTTCCGG
TTGGCAGATGTTCCGCCGGGTGACCTTGCCAAACATTCGCTGGGCGCTGTTGTACGGCGTGGTCTTGACCAACGCGCGCG
CCATCGGTGAGTTCGGCGCGGTATCGGTAGTGTCCGGTTCTATTCGCGGCGAGACTTTCAGCTTGCCGCTGCAGGTTGAG
TTGTTGCAACAGGATTACAACGCGGTCGGTTCCTTTACCGCCGCCGGTTTGCTGACCCTGATGGCGATAGTGACCCTATT
TTTGAAGAGTGGCCTGCAATGGCGTCTGGAACGTCAGAATGCACGTCTCGAGCGGGAGGAAAATCATGAGCATTGA

Upstream 100 bases:

>100_bases
CCAGTGCGATTGCCTCGGTGATCCTGGCGGCCTCGCTGCTGTTGCTGTTCAGCATTAACGTTCTGCAGAGCCGCTTTGGC
CGACGTATCGGGGGGCATTG

Downstream 100 bases:

>100_bases
GATTAACGGTATCAATAAGTTTTTCGGTCGTACCAAGGTATTGAACGATATCTCGCTCGACATTGCCTCCGGTGAGATGG
TGGCACTGCTGGGGCCGTCC

Product: sulfate/thiosulfate transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MADISEFNGVERPRVNWGKWTLIGIGVLFSVLLLVVPIVSIFAEAFSKGIGAMWGNLVDHDMLHAIWLTVLIALITVPFN
LIFGTLLAWLVTRFTFPGRQLLLTLIDIPFAVSPVVAGLIYLLFYGSNGLLGGWLDAHNIQLMFSWPGMVLVTIFVTCPF
VVRELVPMMFSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETFSLPLQVE
LLQQDYNAVGSFTAAGLLTLMAIVTLFLKSGLQWRLERQNARLEREENHEH

Sequences:

>Translated_291_residues
MADISEFNGVERPRVNWGKWTLIGIGVLFSVLLLVVPIVSIFAEAFSKGIGAMWGNLVDHDMLHAIWLTVLIALITVPFN
LIFGTLLAWLVTRFTFPGRQLLLTLIDIPFAVSPVVAGLIYLLFYGSNGLLGGWLDAHNIQLMFSWPGMVLVTIFVTCPF
VVRELVPMMFSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETFSLPLQVE
LLQQDYNAVGSFTAAGLLTLMAIVTLFLKSGLQWRLERQNARLEREENHEH
>Mature_290_residues
ADISEFNGVERPRVNWGKWTLIGIGVLFSVLLLVVPIVSIFAEAFSKGIGAMWGNLVDHDMLHAIWLTVLIALITVPFNL
IFGTLLAWLVTRFTFPGRQLLLTLIDIPFAVSPVVAGLIYLLFYGSNGLLGGWLDAHNIQLMFSWPGMVLVTIFVTCPFV
VRELVPMMFSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETFSLPLQVEL
LQQDYNAVGSFTAAGLLTLMAIVTLFLKSGLQWRLERQNARLEREENHEH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=291, Percent_Identity=79.0378006872852, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1788764, Length=200, Percent_Identity=39.5, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786980, Length=220, Percent_Identity=32.7272727272727, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32276; Mature: 32144

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADISEFNGVERPRVNWGKWTLIGIGVLFSVLLLVVPIVSIFAEAFSKGIGAMWGNLVDH
CCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMLHAIWLTVLIALITVPFNLIFGTLLAWLVTRFTFPGRQLLLTLIDIPFAVSPVVAGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHH
YLLFYGSNGLLGGWLDAHNIQLMFSWPGMVLVTIFVTCPFVVRELVPMMFSQGSQEDEAA
HHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
ILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETFSLPLQVE
EEEECCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCHHHEECCCCCCEEECCHHHH
LLQQDYNAVGSFTAAGLLTLMAIVTLFLKSGLQWRLERQNARLEREENHEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ADISEFNGVERPRVNWGKWTLIGIGVLFSVLLLVVPIVSIFAEAFSKGIGAMWGNLVDH
CCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMLHAIWLTVLIALITVPFNLIFGTLLAWLVTRFTFPGRQLLLTLIDIPFAVSPVVAGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHH
YLLFYGSNGLLGGWLDAHNIQLMFSWPGMVLVTIFVTCPFVVRELVPMMFSQGSQEDEAA
HHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
ILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETFSLPLQVE
EEEECCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCHHHEECCCCCCEEECCHHHH
LLQQDYNAVGSFTAAGLLTLMAIVTLFLKSGLQWRLERQNARLEREENHEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]