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The map label for this gene is yfeR [H]

Identifier: 157371678

GI number: 157371678

Start: 3811269

End: 3812189

Strand: Reverse

Name: yfeR [H]

Synonym: Spro_3441

Alternate gene names: 157371678

Gene position: 3812189-3811269 (Counterclockwise)

Preceding gene: 157371680

Following gene: 157371677

Centisome position: 69.96

GC content: 60.48

Gene sequence:

>921_bases
ATGAATTACTCGATTAAACAACTCAAAGTCTTTGTCGCTATTGCCCGGCACCGCAGTTTCAGCCGGGCGGGCGAGGCCAT
TGGGCTGACGCAGTCGGCGGTCAGCCACAGCGTGAAAGAGCTGGAGGCGGAGGTCGGCGTTCGCCTGCTCGATCGCACCA
CCCGTGAAGTGTTGCTGACCGACGCCGGGCAACGGCTGGCCAACCGGGTTGAACGTTTACTGGATGAGTTGCAGTCGTCA
TTGTTGGATGCGCGCAGCTTTGGCGTGCTACGCAGCGGTACGGTGCGGGTGGCATCGAGCCAGACCATCTCCGCGCACCT
GATGCCGCAGTGCATTGCAGCCGGGGAAAAGCAGTATCCGGATATCCGCATCATGCTGCGTGACCAGGCGCAGCAGCAGG
TGCTGCACAGCATTCGCAACGCCGAGGTCGATTTTGGCATCGTGGTCGATCCGGTGCAGGCGTTGGATCTGGACTGTGAA
CCGATCCTGCACGAACCTTTCCTGTTGCTGTGCCGTAACGATCACCCGTTTGCTGAATTGCCCGAAGTGCACTGGTCGGC
GCTGAACGGCAGCCGTTTGGTGTTGCAGGATTATGCTTCAGGTAGTCGGCCACTGATTGACAGCGCGCTGCGCCAACAAG
GGGTGGAAGCGACGGTAGTGCAGGAGATCGGCCACCCGGCTACGCTGTTTCCTATGGTGGCCGCGGGTATCGGCATCAGT
ATTTTCCCCGCGCTGGCCTTACCCTTACCGGAGGGCGGCCAATTGAAGGTTCGCCGATTGGTGCCGGAAATCAACCGTGC
GCTGATGCTGGTACGGCGTAAAAACCGCTCGCTGACACCGGCAGCAGAGGTCATCTGGCAGGTGGTGGGGCAGCAGGCGG
CCTTGCTGCAACAACAGCGTCAGCGGCAGGCAGATTACTGA

Upstream 100 bases:

>100_bases
CTCATGGCGGCGTACTCGAAGAAAAATCAATGCGCCCATTGTCGCGCGACCGGATATAATAATTAAATTGATTTATTTAA
TTCATATATGAATAAAAAAC

Downstream 100 bases:

>100_bases
GTCAAATATACACATCCACGGCGTTGTGCGCGGTAGCCTGTTTATTGAACAGCATTGACGGTCGGGTTAATCGGCGTACT
ATAACGAATATAAGCGATAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNYSIKQLKVFVAIARHRSFSRAGEAIGLTQSAVSHSVKELEAEVGVRLLDRTTREVLLTDAGQRLANRVERLLDELQSS
LLDARSFGVLRSGTVRVASSQTISAHLMPQCIAAGEKQYPDIRIMLRDQAQQQVLHSIRNAEVDFGIVVDPVQALDLDCE
PILHEPFLLLCRNDHPFAELPEVHWSALNGSRLVLQDYASGSRPLIDSALRQQGVEATVVQEIGHPATLFPMVAAGIGIS
IFPALALPLPEGGQLKVRRLVPEINRALMLVRRKNRSLTPAAEVIWQVVGQQAALLQQQRQRQADY

Sequences:

>Translated_306_residues
MNYSIKQLKVFVAIARHRSFSRAGEAIGLTQSAVSHSVKELEAEVGVRLLDRTTREVLLTDAGQRLANRVERLLDELQSS
LLDARSFGVLRSGTVRVASSQTISAHLMPQCIAAGEKQYPDIRIMLRDQAQQQVLHSIRNAEVDFGIVVDPVQALDLDCE
PILHEPFLLLCRNDHPFAELPEVHWSALNGSRLVLQDYASGSRPLIDSALRQQGVEATVVQEIGHPATLFPMVAAGIGIS
IFPALALPLPEGGQLKVRRLVPEINRALMLVRRKNRSLTPAAEVIWQVVGQQAALLQQQRQRQADY
>Mature_306_residues
MNYSIKQLKVFVAIARHRSFSRAGEAIGLTQSAVSHSVKELEAEVGVRLLDRTTREVLLTDAGQRLANRVERLLDELQSS
LLDARSFGVLRSGTVRVASSQTISAHLMPQCIAAGEKQYPDIRIMLRDQAQQQVLHSIRNAEVDFGIVVDPVQALDLDCE
PILHEPFLLLCRNDHPFAELPEVHWSALNGSRLVLQDYASGSRPLIDSALRQQGVEATVVQEIGHPATLFPMVAAGIGIS
IFPALALPLPEGGQLKVRRLVPEINRALMLVRRKNRSLTPAAEVIWQVVGQQAALLQQQRQRQADY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=306, Percent_Identity=65.6862745098039, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=33.0985915492958, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI157672245, Length=297, Percent_Identity=27.9461279461279, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790399, Length=278, Percent_Identity=29.8561151079137, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787879, Length=247, Percent_Identity=27.1255060728745, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788887, Length=279, Percent_Identity=25.8064516129032, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788481, Length=283, Percent_Identity=25.4416961130742, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787128, Length=126, Percent_Identity=34.9206349206349, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787601, Length=174, Percent_Identity=28.735632183908, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=28.1632653061224, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367136, Length=238, Percent_Identity=25.2100840336134, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786401, Length=178, Percent_Identity=28.0898876404494, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788296, Length=248, Percent_Identity=26.2096774193548, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081904, Length=175, Percent_Identity=26.8571428571429, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788706, Length=169, Percent_Identity=27.810650887574, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787589, Length=122, Percent_Identity=32.7868852459016, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789173, Length=171, Percent_Identity=30.4093567251462, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787530, Length=249, Percent_Identity=22.0883534136546, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786508, Length=186, Percent_Identity=27.9569892473118, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=30.327868852459, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786713, Length=184, Percent_Identity=28.804347826087, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=242, Percent_Identity=21.900826446281, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789506, Length=247, Percent_Identity=22.6720647773279, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33873; Mature: 33873

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSIKQLKVFVAIARHRSFSRAGEAIGLTQSAVSHSVKELEAEVGVRLLDRTTREVLLT
CCCCHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAGQRLANRVERLLDELQSSLLDARSFGVLRSGTVRVASSQTISAHLMPQCIAAGEKQYP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
DIRIMLRDQAQQQVLHSIRNAEVDFGIVVDPVQALDLDCEPILHEPFLLLCRNDHPFAEL
CEEEEEHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCHHHCCCEEEEECCCCCCHHC
PEVHWSALNGSRLVLQDYASGSRPLIDSALRQQGVEATVVQEIGHPATLFPMVAAGIGIS
CHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCHH
IFPALALPLPEGGQLKVRRLVPEINRALMLVRRKNRSLTPAAEVIWQVVGQQAALLQQQR
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
QRQADY
HHCCCC
>Mature Secondary Structure
MNYSIKQLKVFVAIARHRSFSRAGEAIGLTQSAVSHSVKELEAEVGVRLLDRTTREVLLT
CCCCHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAGQRLANRVERLLDELQSSLLDARSFGVLRSGTVRVASSQTISAHLMPQCIAAGEKQYP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
DIRIMLRDQAQQQVLHSIRNAEVDFGIVVDPVQALDLDCEPILHEPFLLLCRNDHPFAEL
CEEEEEHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCHHHCCCEEEEECCCCCCHHC
PEVHWSALNGSRLVLQDYASGSRPLIDSALRQQGVEATVVQEIGHPATLFPMVAAGIGIS
CHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCHH
IFPALALPLPEGGQLKVRRLVPEINRALMLVRRKNRSLTPAAEVIWQVVGQQAALLQQQR
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
QRQADY
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]