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The map label for this gene is bdbD [H]

Identifier: 157371586

GI number: 157371586

Start: 3705206

End: 3705922

Strand: Reverse

Name: bdbD [H]

Synonym: Spro_3349

Alternate gene names: 157371586

Gene position: 3705922-3705206 (Counterclockwise)

Preceding gene: 157371587

Following gene: 157371585

Centisome position: 68.01

GC content: 55.79

Gene sequence:

>717_bases
ATGAAAAAATTAATGATTTTACTGATGTTGATCGCCACCCCTGTCTGGGCCGCTGCCCCATTTACTCCAGAACAGGAAGT
CCGCATTAAAGAGCTGATCCGCGAAACGCTGGTGTCGAACCCGGATATTCTGGCGCAGGCGGTCGATGCCTGGCAGCAGC
AAACCGCCGGCCAGCAAATCAGCCAGGCGATCAAGCAAAACGCCAAAGCCCTGTATGAAGACCCGGCCAGCCCGCGTCTG
GGGGCGGCCAACGCCAAACTGACGCTGGTGACCTTTACCGATTACAACTGTCCGTACTGCAAGCGTTTTGATCCGATGCT
GGAGAAGATCGTCAAACAATACCCGGATGTGGCGTTGGTGGTGAAATTATTGCCGTTCAAAGGCGAAAGCTCGGTCAGTT
CGGCACGGGTGGCATTGACTGCCTGGCAGCAGCATCCGGACCAGTTTTGGGCGTTACACCAGCGGCTGATGGCGAAAAAA
GGTTTCCACGACACCGCCAGCATTGCCGCTGCTCAGCAGAAAACCGGAGTGAAAGAAGTAGCACCCAGTGAGCTGAGCAT
GACCACGCTGCGCACTAACATGGAGCTGGCAGAAAAATTGGGCGTGCAGGGGACGCCGGCAACGCTGATCGGCGATCAGA
TGTTGCCGGGGGCAGTATCTTACGAGGAGCTGGAGGCGATGGTGAAACAGCAATTGGCGAAGGTCAAAAATGGCTAG

Upstream 100 bases:

>100_bases
AAATTTATGGCCCCGGCAGGCGCGACGGCGTGGTGTTGTCCCCACTGTTGACCCGCGATGCCGTATTGCAAACCCTGTCC
GCCGCCAAAGGAAATTCACA

Downstream 100 bases:

>100_bases
GCTGCGGCGTTGGGCGCGGGAGCTGCTGATCCTGCTGTTGATTGTCCTGGTGGCGGCGTTCGGCATGGACTGGCTGCGTG
CACCGCAGGCTCCGCCAGCC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Disulfide oxidoreductase D; Thiol-disulfide oxidoreductase D [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKKLMILLMLIATPVWAAAPFTPEQEVRIKELIRETLVSNPDILAQAVDAWQQQTAGQQISQAIKQNAKALYEDPASPRL
GAANAKLTLVTFTDYNCPYCKRFDPMLEKIVKQYPDVALVVKLLPFKGESSVSSARVALTAWQQHPDQFWALHQRLMAKK
GFHDTASIAAAQQKTGVKEVAPSELSMTTLRTNMELAEKLGVQGTPATLIGDQMLPGAVSYEELEAMVKQQLAKVKNG

Sequences:

>Translated_238_residues
MKKLMILLMLIATPVWAAAPFTPEQEVRIKELIRETLVSNPDILAQAVDAWQQQTAGQQISQAIKQNAKALYEDPASPRL
GAANAKLTLVTFTDYNCPYCKRFDPMLEKIVKQYPDVALVVKLLPFKGESSVSSARVALTAWQQHPDQFWALHQRLMAKK
GFHDTASIAAAQQKTGVKEVAPSELSMTTLRTNMELAEKLGVQGTPATLIGDQMLPGAVSYEELEAMVKQQLAKVKNG
>Mature_238_residues
MKKLMILLMLIATPVWAAAPFTPEQEVRIKELIRETLVSNPDILAQAVDAWQQQTAGQQISQAIKQNAKALYEDPASPRL
GAANAKLTLVTFTDYNCPYCKRFDPMLEKIVKQYPDVALVVKLLPFKGESSVSSARVALTAWQQHPDQFWALHQRLMAKK
GFHDTASIAAAQQKTGVKEVAPSELSMTTLRTNMELAEKLGVQGTPATLIGDQMLPGAVSYEELEAMVKQQLAKVKNG

Specific function: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26247; Mature: 26247

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLMILLMLIATPVWAAAPFTPEQEVRIKELIRETLVSNPDILAQAVDAWQQQTAGQQI
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SQAIKQNAKALYEDPASPRLGAANAKLTLVTFTDYNCPYCKRFDPMLEKIVKQYPDVALV
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEH
VKLLPFKGESSVSSARVALTAWQQHPDQFWALHQRLMAKKGFHDTASIAAAQQKTGVKEV
HHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHH
APSELSMTTLRTNMELAEKLGVQGTPATLIGDQMLPGAVSYEELEAMVKQQLAKVKNG
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKLMILLMLIATPVWAAAPFTPEQEVRIKELIRETLVSNPDILAQAVDAWQQQTAGQQI
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SQAIKQNAKALYEDPASPRLGAANAKLTLVTFTDYNCPYCKRFDPMLEKIVKQYPDVALV
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEH
VKLLPFKGESSVSSARVALTAWQQHPDQFWALHQRLMAKKGFHDTASIAAAQQKTGVKEV
HHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHH
APSELSMTTLRTNMELAEKLGVQGTPATLIGDQMLPGAVSYEELEAMVKQQLAKVKNG
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11844773; 11744713 [H]