Click here to switch to the map view.

The map label for this gene is rstA [H]

Identifier: 157370830

GI number: 157370830

Start: 2847908

End: 2848669

Strand: Direct

Name: rstA [H]

Synonym: Spro_2590

Alternate gene names: 157370830

Gene position: 2847908-2848669 (Clockwise)

Preceding gene: 157370829

Following gene: 157370831

Centisome position: 52.27

GC content: 54.59

Gene sequence:

>762_bases
ATGCTGAATTTCGTTATTCTGATAAAACCGCTGAATATGCATAAAATTGTTTTTGTGGAAGACGATCCCGAAGTCGGCAA
ACTGATTGCCGCCTATCTGGGCAAGCACGACATTGAAGTGTTGATTGAGCCACGCGGCGACAGTGCACAGGCCCGCATCG
AGCTGGAGCAACCTGATTTGGTGCTGCTGGATATTATGTTGCCCGGCAAGGATGGTATGACGCTGTGCCGTGATTTGCGC
CCAACCTTCCCCGGCCCGATCGTGCTGCTCACCTCACTCGACAGCGATATGAACCATATTCTTTCGCTGGAAATGGGCGC
CAACGATTACATCCTGAAGACCACGCCACCGGCAGTGTTACTGGCGCGACTGCGTTTGCACCTGCGTCAGCATGGCAGCC
AGCCAAAGGAAGAGTCAACACAACCGCTCACTCAACACAACGCCCTGCACTTTGGCCTGTTATGCATCGACCCGGTTAAC
CGGCAGGTGACGTTGGGTGAAGAGGTCATCACCCTTTCCACCTCAGATTTTGATCTGCTGTGGGAACTGGCCACCCACGC
CGGCCAAATAATGGATCGCGAAGCCCTGCTGCAGAACCTGCGTGGCGTGAGTTATGACGGTCTGGACCGCAGTATAGACG
TGGCGATTTCCCGCCTGCGCCGCAAACTGTACGACAATGCCCTGGAACCCTTCCGCGTCAAAACCGTGCGTAATAAAGGT
TACCTGTTCGCTCCGAATGCCTGGGAGTTCGTGCAGCAATGA

Upstream 100 bases:

>100_bases
CTGGACAGTCGCTATGTCACCGGCCGTACCCACGGTGTCGACGGCGGACGCCCGCTGCGCTAACGCATGATCTGCATGGC
GTATCGCGGAGCCCCGCGTT

Downstream 100 bases:

>100_bases
GAAAGCTCTTTGTGCAGTTCTTCCTGCTGCTTTTCGTGTGTTTCCTGGTGATGGCAATGCTGGTGGGGTTGGTGTACAAA
GTCACCGCCGAACGCGCCGG

Product: DNA-binding transcriptional regulator RstA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLNFVILIKPLNMHKIVFVEDDPEVGKLIAAYLGKHDIEVLIEPRGDSAQARIELEQPDLVLLDIMLPGKDGMTLCRDLR
PTFPGPIVLLTSLDSDMNHILSLEMGANDYILKTTPPAVLLARLRLHLRQHGSQPKEESTQPLTQHNALHFGLLCIDPVN
RQVTLGEEVITLSTSDFDLLWELATHAGQIMDREALLQNLRGVSYDGLDRSIDVAISRLRRKLYDNALEPFRVKTVRNKG
YLFAPNAWEFVQQ

Sequences:

>Translated_253_residues
MLNFVILIKPLNMHKIVFVEDDPEVGKLIAAYLGKHDIEVLIEPRGDSAQARIELEQPDLVLLDIMLPGKDGMTLCRDLR
PTFPGPIVLLTSLDSDMNHILSLEMGANDYILKTTPPAVLLARLRLHLRQHGSQPKEESTQPLTQHNALHFGLLCIDPVN
RQVTLGEEVITLSTSDFDLLWELATHAGQIMDREALLQNLRGVSYDGLDRSIDVAISRLRRKLYDNALEPFRVKTVRNKG
YLFAPNAWEFVQQ
>Mature_253_residues
MLNFVILIKPLNMHKIVFVEDDPEVGKLIAAYLGKHDIEVLIEPRGDSAQARIELEQPDLVLLDIMLPGKDGMTLCRDLR
PTFPGPIVLLTSLDSDMNHILSLEMGANDYILKTTPPAVLLARLRLHLRQHGSQPKEESTQPLTQHNALHFGLLCIDPVN
RQVTLGEEVITLSTSDFDLLWELATHAGQIMDREALLQNLRGVSYDGLDRSIDVAISRLRRKLYDNALEPFRVKTVRNKG
YLFAPNAWEFVQQ

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=75.3138075313807, Blast_Score=343, Evalue=5e-96,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=33.6170212765957, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=34.5833333333333, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=32.9004329004329, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082012, Length=184, Percent_Identity=36.9565217391304, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786599, Length=237, Percent_Identity=31.6455696202532, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=33.4782608695652, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787229, Length=239, Percent_Identity=30.5439330543933, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790552, Length=235, Percent_Identity=30.2127659574468, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=191, Percent_Identity=30.3664921465969, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=28.1385281385281, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787375, Length=240, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28590; Mature: 28590

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFVILIKPLNMHKIVFVEDDPEVGKLIAAYLGKHDIEVLIEPRGDSAQARIELEQPDL
CCEEEEEEEECCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCE
VLLDIMLPGKDGMTLCRDLRPTFPGPIVLLTSLDSDMNHILSLEMGANDYILKTTPPAVL
EEEEEEECCCCCHHHHHHCCCCCCCCEEEEEECCCCCHHEEEEEECCCCEEEECCCHHHH
LARLRLHLRQHGSQPKEESTQPLTQHNALHFGLLCIDPVNRQVTLGEEVITLSTSDFDLL
HHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEEEECCCCCEEEECCEEEEEECCCHHHH
WELATHAGQIMDREALLQNLRGVSYDGLDRSIDVAISRLRRKLYDNALEPFRVKTVRNKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
YLFAPNAWEFVQQ
EEECCCHHHHHCC
>Mature Secondary Structure
MLNFVILIKPLNMHKIVFVEDDPEVGKLIAAYLGKHDIEVLIEPRGDSAQARIELEQPDL
CCEEEEEEEECCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCE
VLLDIMLPGKDGMTLCRDLRPTFPGPIVLLTSLDSDMNHILSLEMGANDYILKTTPPAVL
EEEEEEECCCCCHHHHHHCCCCCCCCEEEEEECCCCCHHEEEEEECCCCEEEECCCHHHH
LARLRLHLRQHGSQPKEESTQPLTQHNALHFGLLCIDPVNRQVTLGEEVITLSTSDFDLL
HHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEEEECCCCCEEEECCEEEEEECCCHHHH
WELATHAGQIMDREALLQNLRGVSYDGLDRSIDVAISRLRRKLYDNALEPFRVKTVRNKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
YLFAPNAWEFVQQ
EEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]