Click here to switch to the map view.

The map label for this gene is agaR [H]

Identifier: 157370817

GI number: 157370817

Start: 2834140

End: 2834910

Strand: Direct

Name: agaR [H]

Synonym: Spro_2577

Alternate gene names: 157370817

Gene position: 2834140-2834910 (Clockwise)

Preceding gene: 157370816

Following gene: 157370818

Centisome position: 52.01

GC content: 57.2

Gene sequence:

>771_bases
ATGATCAATACCCTAAAACGACGGGAATTAATTATCGACCAGCTTTGTCGCGAAGGCTCAGTGCGCGTCGAGCAACTCAG
CGCCCAGTTTTCGGTTTCCAGCGTCACTATTCGCAGCGACCTGCGCCAACTGGAAAAAAGCGGCTGTGCGGTCCGTGCCT
ATGGCGGCGCAATGCTCAATAAGCAGTTCGCCTTCGATCGTCCGCTACAGGACAAGGGGCGCCTCAATCGCGACGTGAAA
TACGCCATTGCCTGCGCGGCGGCGGAACTGGTCAAAGACGGCGATGCCATCATTCTCGACTCCGGTTCGACCACCAGCCA
AATGGCGCAGCAGCTGGTCGGTAAAAAGGATCTGGTGGTGATGACCAATGCGCTGAATATCGCTTTCGAACTGGCCAACA
ACGAACAGGTTGACCTGATGGTGGTCGGCGGCAGCGTACGACGCAAATCCTGGTCTTTGTATGGCCCGGCCGCCGAGCAA
CACATGCGTCAGTTCCGTTTCGACAAGCTGTTTCTCGGCGTCGACGGTTTTGACCTGATTAGCGGCATCACCACGCCGGA
TCCCGGTGAAGCGCAACTCAACCGCGCCATGTGCGACGTAGCGCGTGAAGTGATCGCCGTAGCGGACGCCAGCAAGTTCG
GCCGCACCAGCTTTTGCATGATCCGTGAAATCGGCCAAATCCAGCGTTTGGTCACCGACAGCCGCATTCCGGAAAGCTAC
CTGCATGCGCTGAACCATTTAGGGGTCGACGTGATTATCGCCGACCGTTAA

Upstream 100 bases:

>100_bases
TAATTCGCCACGAACAACTGAAAGCACTCCTGCCAGATTAACTGCGACGCATTGCGCCGCGGCCGGGTATGGCTACAGCT
AAATCAGGAGTCACGCGTTA

Downstream 100 bases:

>100_bases
CCGAGGTTTTTAAGGAGTTTCAACATGAACGGTTATTTTGCTTACGATGCGGGCTGGCTGGAACAACGACATGCGCTGCA
TACCGCACGTGAGATCTGGC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MINTLKRRELIIDQLCREGSVRVEQLSAQFSVSSVTIRSDLRQLEKSGCAVRAYGGAMLNKQFAFDRPLQDKGRLNRDVK
YAIACAAAELVKDGDAIILDSGSTTSQMAQQLVGKKDLVVMTNALNIAFELANNEQVDLMVVGGSVRRKSWSLYGPAAEQ
HMRQFRFDKLFLGVDGFDLISGITTPDPGEAQLNRAMCDVAREVIAVADASKFGRTSFCMIREIGQIQRLVTDSRIPESY
LHALNHLGVDVIIADR

Sequences:

>Translated_256_residues
MINTLKRRELIIDQLCREGSVRVEQLSAQFSVSSVTIRSDLRQLEKSGCAVRAYGGAMLNKQFAFDRPLQDKGRLNRDVK
YAIACAAAELVKDGDAIILDSGSTTSQMAQQLVGKKDLVVMTNALNIAFELANNEQVDLMVVGGSVRRKSWSLYGPAAEQ
HMRQFRFDKLFLGVDGFDLISGITTPDPGEAQLNRAMCDVAREVIAVADASKFGRTSFCMIREIGQIQRLVTDSRIPESY
LHALNHLGVDVIIADR
>Mature_256_residues
MINTLKRRELIIDQLCREGSVRVEQLSAQFSVSSVTIRSDLRQLEKSGCAVRAYGGAMLNKQFAFDRPLQDKGRLNRDVK
YAIACAAAELVKDGDAIILDSGSTTSQMAQQLVGKKDLVVMTNALNIAFELANNEQVDLMVVGGSVRRKSWSLYGPAAEQ
HMRQFRFDKLFLGVDGFDLISGITTPDPGEAQLNRAMCDVAREVIAVADASKFGRTSFCMIREIGQIQRLVTDSRIPESY
LHALNHLGVDVIIADR

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=45.2380952380952, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1789059, Length=251, Percent_Identity=42.6294820717131, Blast_Score=190, Evalue=9e-50,
Organism=Escherichia coli, GI226510968, Length=250, Percent_Identity=31.6, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789829, Length=239, Percent_Identity=31.3807531380753, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787540, Length=251, Percent_Identity=31.0756972111554, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082344, Length=236, Percent_Identity=27.9661016949153, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788069, Length=228, Percent_Identity=28.0701754385965, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789170, Length=236, Percent_Identity=27.5423728813559, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790753, Length=239, Percent_Identity=26.7782426778243, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790635, Length=249, Percent_Identity=24.8995983935743, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28282; Mature: 28282

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTLKRRELIIDQLCREGSVRVEQLSAQFSVSSVTIRSDLRQLEKSGCAVRAYGGAMLN
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHC
KQFAFDRPLQDKGRLNRDVKYAIACAAAELVKDGDAIILDSGSTTSQMAQQLVGKKDLVV
CCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEE
MTNALNIAFELANNEQVDLMVVGGSVRRKSWSLYGPAAEQHMRQFRFDKLFLGVDGFDLI
EEEEEEEEEEECCCCCEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHEEECCCCHHHH
SGITTPDPGEAQLNRAMCDVAREVIAVADASKFGRTSFCMIREIGQIQRLVTDSRIPESY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHH
LHALNHLGVDVIIADR
HHHHHHCCEEEEEECC
>Mature Secondary Structure
MINTLKRRELIIDQLCREGSVRVEQLSAQFSVSSVTIRSDLRQLEKSGCAVRAYGGAMLN
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHC
KQFAFDRPLQDKGRLNRDVKYAIACAAAELVKDGDAIILDSGSTTSQMAQQLVGKKDLVV
CCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEE
MTNALNIAFELANNEQVDLMVVGGSVRRKSWSLYGPAAEQHMRQFRFDKLFLGVDGFDLI
EEEEEEEEEEECCCCCEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHEEECCCCHHHH
SGITTPDPGEAQLNRAMCDVAREVIAVADASKFGRTSFCMIREIGQIQRLVTDSRIPESY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHH
LHALNHLGVDVIIADR
HHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]