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The map label for this gene is pdxK [H]

Identifier: 157370806

GI number: 157370806

Start: 2820763

End: 2821602

Strand: Direct

Name: pdxK [H]

Synonym: Spro_2566

Alternate gene names: 157370806

Gene position: 2820763-2821602 (Clockwise)

Preceding gene: 157370805

Following gene: 157370811

Centisome position: 51.77

GC content: 54.64

Gene sequence:

>840_bases
ATGCAACAGGTTTCTCAATTACAACCGCCGCAGATTGATGTGATCAGTATTCAATCGCAGGTCGTGTATGGCAGCGTCGG
CAACGGTATCGCCTATCGCACCTTGCTGAAAAAAGGGCTGGAAGCGTTACAGGTACCCAGCGTGCTGTTCGGCTGCCCGC
CCTATTATGGCGCGCCCAGCGGTGGCGTAATTCCGGCCGAGTGGTTCAGCGGCTTTCTCGAGGATTTACTGACCCGCGGC
GTAATGAAACGCACCCGGGCGGTGATCATCGGTTATCTGGGCGACGTTGGCCAATGTCATTTTCTACACACCTGGCTACA
ACGCGTGCGCGCTATCAATCCGCAGATAAAAATTTATATCGACCCGGTGATGGGCGATTACGGTGAAGGCGTTTACGTGG
ATGAGCGTATCGTCAGTTGCTATCGCTCGCCGTTCCTGCAACTGGCTAATGGCCTCACCCCAAACGGTTTCGAACTGGAG
CAACTTTGCGGGCATCCGTTAACCAGCCGAGAGCAAACGCAGCATGCCGCACAGGCGTTATTGAATGACACTACCGAGTG
GGTACTGGTGACCAGTGCGCCAGGCGTGGCGGAAAATGACGATCAGATTGGCTTACTGTTGGTCAGCCACGACGAGGTGC
AAAGCTATACCCATCCCAAGATTCAGTCGAAGGTAAAGGGCACCGGTGACATGTTCACCGCGTTGCTGGTCAGCCATTTG
TTGAACGGGAAAAATCTCAATAGTGCAGTCCTGACCGCCAGCAGTGAGGTCTGCGATGTGCTGACTGAAGCGGCGCATTT
CGGTTTGGAGGAAATCGGCAGCCTGCGTGCCTTGAAATAG

Upstream 100 bases:

>100_bases
TTTGCGCCAACAGGCTGCGCGCCACGGTACAGAATTAGAACAGCGCGCCCGTCAGGTATTTACGCGGTGGCTGGATAAAG
TCGAACCAAGGATGTTATAG

Downstream 100 bases:

>100_bases
AATAGAACGGAGTGACGGGGCAGCCTGCTGCCCCGCTGATTTCCTATTTAGCGTTTTTTCTTTTTATTGAAATCCAATTC
GAAAGCAAACACTGCGCTCT

Product: pyridoxal kinase

Products: NA

Alternate protein names: PN/PL/PM kinase; Pyridoxal kinase; Pyridoxamine kinase; Vitamin B6 kinase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MQQVSQLQPPQIDVISIQSQVVYGSVGNGIAYRTLLKKGLEALQVPSVLFGCPPYYGAPSGGVIPAEWFSGFLEDLLTRG
VMKRTRAVIIGYLGDVGQCHFLHTWLQRVRAINPQIKIYIDPVMGDYGEGVYVDERIVSCYRSPFLQLANGLTPNGFELE
QLCGHPLTSREQTQHAAQALLNDTTEWVLVTSAPGVAENDDQIGLLLVSHDEVQSYTHPKIQSKVKGTGDMFTALLVSHL
LNGKNLNSAVLTASSEVCDVLTEAAHFGLEEIGSLRALK

Sequences:

>Translated_279_residues
MQQVSQLQPPQIDVISIQSQVVYGSVGNGIAYRTLLKKGLEALQVPSVLFGCPPYYGAPSGGVIPAEWFSGFLEDLLTRG
VMKRTRAVIIGYLGDVGQCHFLHTWLQRVRAINPQIKIYIDPVMGDYGEGVYVDERIVSCYRSPFLQLANGLTPNGFELE
QLCGHPLTSREQTQHAAQALLNDTTEWVLVTSAPGVAENDDQIGLLLVSHDEVQSYTHPKIQSKVKGTGDMFTALLVSHL
LNGKNLNSAVLTASSEVCDVLTEAAHFGLEEIGSLRALK
>Mature_279_residues
MQQVSQLQPPQIDVISIQSQVVYGSVGNGIAYRTLLKKGLEALQVPSVLFGCPPYYGAPSGGVIPAEWFSGFLEDLLTRG
VMKRTRAVIIGYLGDVGQCHFLHTWLQRVRAINPQIKIYIDPVMGDYGEGVYVDERIVSCYRSPFLQLANGLTPNGFELE
QLCGHPLTSREQTQHAAQALLNDTTEWVLVTSAPGVAENDDQIGLLLVSHDEVQSYTHPKIQSKVKGTGDMFTALLVSHL
LNGKNLNSAVLTASSEVCDVLTEAAHFGLEEIGSLRALK

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=238, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788758, Length=251, Percent_Identity=43.4262948207171, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1787924, Length=253, Percent_Identity=28.4584980237154, Blast_Score=107, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17507759, Length=268, Percent_Identity=29.8507462686567, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17507757, Length=278, Percent_Identity=29.136690647482, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320806, Length=261, Percent_Identity=29.1187739463602, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324354, Length=255, Percent_Identity=29.0196078431373, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45553007, Length=240, Percent_Identity=28.3333333333333, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 30434; Mature: 30434

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQVSQLQPPQIDVISIQSQVVYGSVGNGIAYRTLLKKGLEALQVPSVLFGCPPYYGAPS
CCCCHHCCCCCEEEEEEECEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
GGVIPAEWFSGFLEDLLTRGVMKRTRAVIIGYLGDVGQCHFLHTWLQRVRAINPQIKIYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHHCCCEEEEEE
DPVMGDYGEGVYVDERIVSCYRSPFLQLANGLTPNGFELEQLCGHPLTSREQTQHAAQAL
ECCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHH
LNDTTEWVLVTSAPGVAENDDQIGLLLVSHDEVQSYTHPKIQSKVKGTGDMFTALLVSHL
HCCCCCEEEEECCCCCCCCCCCEEEEEEECHHHHHHCCCHHHHHCCCCHHHHHHHHHHHH
LNGKNLNSAVLTASSEVCDVLTEAAHFGLEEIGSLRALK
HCCCCCCHHHEECCHHHHHHHHHHHHHCHHHHHHHCCCC
>Mature Secondary Structure
MQQVSQLQPPQIDVISIQSQVVYGSVGNGIAYRTLLKKGLEALQVPSVLFGCPPYYGAPS
CCCCHHCCCCCEEEEEEECEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
GGVIPAEWFSGFLEDLLTRGVMKRTRAVIIGYLGDVGQCHFLHTWLQRVRAINPQIKIYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHHCCCEEEEEE
DPVMGDYGEGVYVDERIVSCYRSPFLQLANGLTPNGFELEQLCGHPLTSREQTQHAAQAL
ECCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHH
LNDTTEWVLVTSAPGVAENDDQIGLLLVSHDEVQSYTHPKIQSKVKGTGDMFTALLVSHL
HCCCCCEEEEECCCCCCCCCCCEEEEEEECHHHHHHCCCHHHHHCCCCHHHHHHHHHHHH
LNGKNLNSAVLTASSEVCDVLTEAAHFGLEEIGSLRALK
HCCCCCCHHHEECCHHHHHHHHHHHHHCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA