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The map label for this gene is ygcS [H]

Identifier: 157370707

GI number: 157370707

Start: 2702693

End: 2704054

Strand: Direct

Name: ygcS [H]

Synonym: Spro_2467

Alternate gene names: 157370707

Gene position: 2702693-2704054 (Clockwise)

Preceding gene: 157370704

Following gene: 157370708

Centisome position: 49.6

GC content: 56.02

Gene sequence:

>1362_bases
ATGCAAAATATGACATCGCAACAAATTCGTATGGATGACGTTCCTTTAAACCGATTCCATCTCAAAATCGCCGGGCTGAT
GTTTGGTGCCCACTTTACCGACGGCTACGTACTGGGCGTCATTGGTTTCGCCCTGGCACAAATCAAACCACAAATGGGGA
TCTCCGCCTTTTGGGAAGGCATGCTCGGCAGCTCAGCGTTGATCGGGCTGTTTATCGGTAGCCTGGCCCTCGGCTGGATC
GCCGATCATATTGGACGGCAAAAAATATTCTGCTTCAGCTTTGTGGTCATCACTCTCGCCTCGGCTCTGCAGTTTTTTGC
CACCACGCCGGAGCAGCTGTTCCTGTTGCGGGTCATGGTGGGCATCGGGCTCGGCGGTGATTTTTCTGTCGGGCATACCA
TGCTTGCCGAGTTCTCCCCGCGTAAACACCGTGGCGTACTGCTGGGTTCCTTCAGCGTGATTTGGACCTTCGGCTATGTT
GCGGCCGGATTTGCCGGGCACTTCCTGACGGCGATGGGTCCGGATGCCTGGCGTTGGCTTCTTTCATCTTCCGCAGTGCC
GGCATTCATCATTCTGATCATGCGTATCGGCACGCCGGAATCCCCCCGCTGGCTGCTGGGCAAAGGCCAGCGCGAACAGG
CCATGGCAATTGTTCACCGCTATTTCGGCCCGAATGTGATGCTGGTTGGTGAAGCGCCAACCCTCAGCAAACCGCGTTTT
ATGTCGCTGTTTGGCCCCCTTTATCGTCGTCGTACCGCCTTCAACAGCCTGTTCTTTGTCTGCCTGGTGATCCCGTACTT
CGCGATTTATACCTTCTTGCCGTCGATTTTGCAGGTGATGGGTCTGGATCAAAACTTCTCTACTGACCTGTTGCTCAATG
GTCTGCTGATCGTCGGAGCGCTGCTGGGTATTGTGCTGACGATGTTCTGTTCACGACGGGGTTTCCTGATTGGTGCCTTC
GTGTTCCTGGCCGCCTGTCTGATGTTGCTGAGCCTCATTCCCGCCAGCCAAACGGCCTGGCTGATTGCCCTGTTTGCCGC
CTTTACGCTGGTGATGTCGGCGGTCAGCAACCTGGTCGGCGTTTTCCCGGCGGAAAGCTTCCCGACGGAAGTGCGATCGA
TGGGCGTCGGCTTTGCTACCTCAATGAGCCGTTTGGGATCGGCTATCGGCACCGGCCTGTTGCCGTTGGCGATTGTCCAC
TATGGCATGCCCGCCACCACCGGCATTCTGGCGGTGATTTTAATTATTGGCGCATTGGTCTCCATCGCCTGGGCGCCGGA
AACCAAGGGTTTAACCCTGGTTGATGCCAGCCAGGATCCTGCACAGCGCGCAGAAAATGCTTTGCTGACATCAGCTAAAT
AA

Upstream 100 bases:

>100_bases
ACGCACTCGCCGAATACCCCGTTCCGCTGCCACATTGTTCACGCATTCAAAACAAAAATCTAACAATAACCCTACACCGC
TCCTACCGGAGGACAGGTCA

Downstream 100 bases:

>100_bases
CACCATCTTATTGAAAACAGGAGTAATGACGTGGAAATGTATATCGGTGAAGGTTTTGAGGGGAATGGCGTAAACGCCTC
GCACATCAATATTATGATTG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MQNMTSQQIRMDDVPLNRFHLKIAGLMFGAHFTDGYVLGVIGFALAQIKPQMGISAFWEGMLGSSALIGLFIGSLALGWI
ADHIGRQKIFCFSFVVITLASALQFFATTPEQLFLLRVMVGIGLGGDFSVGHTMLAEFSPRKHRGVLLGSFSVIWTFGYV
AAGFAGHFLTAMGPDAWRWLLSSSAVPAFIILIMRIGTPESPRWLLGKGQREQAMAIVHRYFGPNVMLVGEAPTLSKPRF
MSLFGPLYRRRTAFNSLFFVCLVIPYFAIYTFLPSILQVMGLDQNFSTDLLLNGLLIVGALLGIVLTMFCSRRGFLIGAF
VFLAACLMLLSLIPASQTAWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTGLLPLAIVH
YGMPATTGILAVILIIGALVSIAWAPETKGLTLVDASQDPAQRAENALLTSAK

Sequences:

>Translated_453_residues
MQNMTSQQIRMDDVPLNRFHLKIAGLMFGAHFTDGYVLGVIGFALAQIKPQMGISAFWEGMLGSSALIGLFIGSLALGWI
ADHIGRQKIFCFSFVVITLASALQFFATTPEQLFLLRVMVGIGLGGDFSVGHTMLAEFSPRKHRGVLLGSFSVIWTFGYV
AAGFAGHFLTAMGPDAWRWLLSSSAVPAFIILIMRIGTPESPRWLLGKGQREQAMAIVHRYFGPNVMLVGEAPTLSKPRF
MSLFGPLYRRRTAFNSLFFVCLVIPYFAIYTFLPSILQVMGLDQNFSTDLLLNGLLIVGALLGIVLTMFCSRRGFLIGAF
VFLAACLMLLSLIPASQTAWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTGLLPLAIVH
YGMPATTGILAVILIIGALVSIAWAPETKGLTLVDASQDPAQRAENALLTSAK
>Mature_453_residues
MQNMTSQQIRMDDVPLNRFHLKIAGLMFGAHFTDGYVLGVIGFALAQIKPQMGISAFWEGMLGSSALIGLFIGSLALGWI
ADHIGRQKIFCFSFVVITLASALQFFATTPEQLFLLRVMVGIGLGGDFSVGHTMLAEFSPRKHRGVLLGSFSVIWTFGYV
AAGFAGHFLTAMGPDAWRWLLSSSAVPAFIILIMRIGTPESPRWLLGKGQREQAMAIVHRYFGPNVMLVGEAPTLSKPRF
MSLFGPLYRRRTAFNSLFFVCLVIPYFAIYTFLPSILQVMGLDQNFSTDLLLNGLLIVGALLGIVLTMFCSRRGFLIGAF
VFLAACLMLLSLIPASQTAWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTGLLPLAIVH
YGMPATTGILAVILIIGALVSIAWAPETKGLTLVDASQDPAQRAENALLTSAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI302148518, Length=371, Percent_Identity=24.7978436657682, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4506999, Length=446, Percent_Identity=25.7847533632287, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI213021148, Length=427, Percent_Identity=23.8875878220141, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI203098995, Length=227, Percent_Identity=28.6343612334802, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4507005, Length=389, Percent_Identity=24.1645244215938, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI24308167, Length=470, Percent_Identity=23.8297872340426, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI7662270, Length=288, Percent_Identity=26.0416666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI24497490, Length=387, Percent_Identity=25.5813953488372, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI23510410, Length=391, Percent_Identity=25.3196930946292, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI24497497, Length=401, Percent_Identity=23.6907730673317, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI90669191, Length=401, Percent_Identity=23.6907730673317, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI8923870, Length=397, Percent_Identity=25.4408060453401, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI11415038, Length=387, Percent_Identity=24.2894056847545, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI166197673, Length=358, Percent_Identity=24.5810055865922, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI24497476, Length=401, Percent_Identity=22.4438902743142, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI20070188, Length=401, Percent_Identity=22.4438902743142, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI21553331, Length=308, Percent_Identity=23.0519480519481, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI166064021, Length=388, Percent_Identity=24.7422680412371, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI296080734, Length=153, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI296080721, Length=163, Percent_Identity=26.9938650306748, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI296080719, Length=163, Percent_Identity=26.9938650306748, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI24497499, Length=163, Percent_Identity=26.9938650306748, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI262399383, Length=231, Percent_Identity=25.1082251082251, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87082159, Length=435, Percent_Identity=60.2298850574713, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1786229, Length=431, Percent_Identity=34.8027842227378, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1788068, Length=468, Percent_Identity=25, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788074, Length=463, Percent_Identity=23.5421166306695, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790463, Length=451, Percent_Identity=24.1685144124169, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789207, Length=219, Percent_Identity=28.7671232876712, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789312, Length=443, Percent_Identity=23.4762979683973, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082404, Length=392, Percent_Identity=24.234693877551, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71980582, Length=385, Percent_Identity=25.7142857142857, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71980584, Length=385, Percent_Identity=25.7142857142857, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564663, Length=457, Percent_Identity=23.8512035010941, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17565978, Length=216, Percent_Identity=26.3888888888889, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565976, Length=194, Percent_Identity=25.7731958762887, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71988651, Length=210, Percent_Identity=29.0476190476191, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193209824, Length=429, Percent_Identity=23.7762237762238, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323512, Length=523, Percent_Identity=22.3709369024857, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320595, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323653, Length=353, Percent_Identity=23.2294617563739, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19922616, Length=404, Percent_Identity=24.5049504950495, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640198, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24640196, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24640200, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24649622, Length=414, Percent_Identity=23.6714975845411, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649618, Length=353, Percent_Identity=26.9121813031161, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24668456, Length=409, Percent_Identity=24.4498777506112, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19922874, Length=388, Percent_Identity=22.9381443298969, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 48911; Mature: 48911

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]