Click here to switch to the map view.

The map label for this gene is yegH [H]

Identifier: 157369823

GI number: 157369823

Start: 1723194

End: 1724780

Strand: Reverse

Name: yegH [H]

Synonym: Spro_1580

Alternate gene names: 157369823

Gene position: 1724780-1723194 (Counterclockwise)

Preceding gene: 157369846

Following gene: 157369818

Centisome position: 31.65

GC content: 54.38

Gene sequence:

>1587_bases
ATGGAATGGATCGCAGATCCAACAATTTGGGCCGGCCTGGCCACTCTGGTCGTGCTGGAAATCGTTCTGGGTATAGACAA
CCTTATCTTTATCGCCATCCTGGCGGAAAAATTACCAAAACATCAAAGAGATAAAGCCCGCATTGTTGGTTTAATGCTGG
CGTTGCTGATGCGCCTGGCGCTGTTGGCCTCCATCTCATGGTTGGCGACACTGACTCAACCGTTGTTTTTTGCCGGCGGA
CATCCCTTCAGCGGCCGCGATCTGATAATGCTGGTTGGGGGCATATTCCTGCTGTTCAAAGCCACCATGGAGCTCAACGA
GCGACTCGAGGGTAAAGATGAAGAGCAACAGGGCCAGCGCAAAGGCGCCCGCTTCTGGCCAGTGGTGGCACAAATCGTGG
TGCTGGATGCGGTCTTCTCGCTCGACTCGGTGATCACCGCCGTCGGCATGGTCGATCACCTGGCAGTCATGATGCTTGCG
GTGTGTATCGCTATCGGCCTGATGTTGCTTGCCAGTAAGCCGCTGACGCGTTTCGTCAATGCCCACCCTACGATTGTCAT
CCTGTGCTTGAGCTTTCTGTTGATGATCGGTTTCAGTCTGGTTGCCGAAGGCTTTGGCTACCACATTCCGAAAGGTTATC
TGTACGCCGCCATTGGTTTCTCGGTGATGATTGAAGCTTTGAACCAGCTATCGCAGTTCAATCGCCGCCGTTTTCTTTCC
AAAGTGCGACCATTGCGCGAACGGACGGCAGAGGCCGTGCTGCGCATGCTGAGCGGCAAACATGAAGAAGCAGAAGTCGA
CAGCCACTCAGCCAACCTGCTGGCTGACAGCGACAGTGAGAGCGGCGAGATTTTCAACCAGCAGGAACGCCATATGATCG
AACGCGTGTTGGGAATGGCCCAGCGTACGGTAAGCAGCATCATGACTTCTCGACATGATGTGGAATACCTTGAGCTGAAT
GACCCACAGGAAAAGCTGACCCAACTGCTGGAAAAAAACCAGCATACGCGCATCGTGGTGGTGGAAAACAGTGCCAGCGA
TGAACCGCTCGGCGTTATTCACACCATTGACGTGTTGAAACAACAGCTGACCCAAGCCCCGCTAGATTTACGCGCGCTGG
TGCTGCAGCCGCTGATTTTCCCCGAGCAGTTAACCCTGCTGAGCGCGCTGGAGCAATTTCGCCAGGCGCAGACCCATTTT
GCCTTTGTCGTAGACGAATTCGGCTCGGTTGAAGGGATAGTCACGCTGACTGATGTGATGGAGACCATTGCAGGCAACCT
GCCGGAAGCCGGAGAGGAAGTCGACGCCCGGCATGACATTGTGCAAAATGATGACGGAAGCTGGACCGCCAACGGTTACA
TGCCGCTGGAGGATCTGGTGTTGTATCTGCCATTACCGCTGGAAGATAAGCGTGAATACCACACGTTGGCCGGCCTGCTG
ATGGAACACAGCCAGCGCATTCCCCAGGAAGGCGAGCAGTTGCGGATCGGTGACTACCTGTTTGAACCGCTGGAAGTCAG
TAGCCACCGTATTTTGAAGGTAAAAATCACCCCGTTGTCGGTACCAGAACCAGACTACGAGGTTTAA

Upstream 100 bases:

>100_bases
AGCAGGCAACTCCCCCGGTTTTAAAGTTGAATTTTCCCGGTGCAACACCCATCATTCACTGGCGGCATAAGCCGTCGAAC
TTACAGGTGAAATTGGGCGT

Downstream 100 bases:

>100_bases
ACCGGGGCCGGGCATCGCTCGGCCGCTATTATAAATGCTGGGGAACCAGTAACTCCGTCGCCACAATCACCACGATCAAC
CCAACAATCACCGGTACCGA

Product: integral membrane protein TerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MEWIADPTIWAGLATLVVLEIVLGIDNLIFIAILAEKLPKHQRDKARIVGLMLALLMRLALLASISWLATLTQPLFFAGG
HPFSGRDLIMLVGGIFLLFKATMELNERLEGKDEEQQGQRKGARFWPVVAQIVVLDAVFSLDSVITAVGMVDHLAVMMLA
VCIAIGLMLLASKPLTRFVNAHPTIVILCLSFLLMIGFSLVAEGFGYHIPKGYLYAAIGFSVMIEALNQLSQFNRRRFLS
KVRPLRERTAEAVLRMLSGKHEEAEVDSHSANLLADSDSESGEIFNQQERHMIERVLGMAQRTVSSIMTSRHDVEYLELN
DPQEKLTQLLEKNQHTRIVVVENSASDEPLGVIHTIDVLKQQLTQAPLDLRALVLQPLIFPEQLTLLSALEQFRQAQTHF
AFVVDEFGSVEGIVTLTDVMETIAGNLPEAGEEVDARHDIVQNDDGSWTANGYMPLEDLVLYLPLPLEDKREYHTLAGLL
MEHSQRIPQEGEQLRIGDYLFEPLEVSSHRILKVKITPLSVPEPDYEV

Sequences:

>Translated_528_residues
MEWIADPTIWAGLATLVVLEIVLGIDNLIFIAILAEKLPKHQRDKARIVGLMLALLMRLALLASISWLATLTQPLFFAGG
HPFSGRDLIMLVGGIFLLFKATMELNERLEGKDEEQQGQRKGARFWPVVAQIVVLDAVFSLDSVITAVGMVDHLAVMMLA
VCIAIGLMLLASKPLTRFVNAHPTIVILCLSFLLMIGFSLVAEGFGYHIPKGYLYAAIGFSVMIEALNQLSQFNRRRFLS
KVRPLRERTAEAVLRMLSGKHEEAEVDSHSANLLADSDSESGEIFNQQERHMIERVLGMAQRTVSSIMTSRHDVEYLELN
DPQEKLTQLLEKNQHTRIVVVENSASDEPLGVIHTIDVLKQQLTQAPLDLRALVLQPLIFPEQLTLLSALEQFRQAQTHF
AFVVDEFGSVEGIVTLTDVMETIAGNLPEAGEEVDARHDIVQNDDGSWTANGYMPLEDLVLYLPLPLEDKREYHTLAGLL
MEHSQRIPQEGEQLRIGDYLFEPLEVSSHRILKVKITPLSVPEPDYEV
>Mature_528_residues
MEWIADPTIWAGLATLVVLEIVLGIDNLIFIAILAEKLPKHQRDKARIVGLMLALLMRLALLASISWLATLTQPLFFAGG
HPFSGRDLIMLVGGIFLLFKATMELNERLEGKDEEQQGQRKGARFWPVVAQIVVLDAVFSLDSVITAVGMVDHLAVMMLA
VCIAIGLMLLASKPLTRFVNAHPTIVILCLSFLLMIGFSLVAEGFGYHIPKGYLYAAIGFSVMIEALNQLSQFNRRRFLS
KVRPLRERTAEAVLRMLSGKHEEAEVDSHSANLLADSDSESGEIFNQQERHMIERVLGMAQRTVSSIMTSRHDVEYLELN
DPQEKLTQLLEKNQHTRIVVVENSASDEPLGVIHTIDVLKQQLTQAPLDLRALVLQPLIFPEQLTLLSALEQFRQAQTHF
AFVVDEFGSVEGIVTLTDVMETIAGNLPEAGEEVDARHDIVQNDDGSWTANGYMPLEDLVLYLPLPLEDKREYHTLAGLL
MEHSQRIPQEGEQLRIGDYLFEPLEVSSHRILKVKITPLSVPEPDYEV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=353, Percent_Identity=23.7960339943343, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI87082033, Length=529, Percent_Identity=71.6446124763705, Blast_Score=751, Evalue=0.0,
Organism=Escherichia coli, GI1788119, Length=518, Percent_Identity=49.4208494208494, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1789197, Length=226, Percent_Identity=51.3274336283186, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1790664, Length=252, Percent_Identity=31.3492063492063, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786879, Length=256, Percent_Identity=26.953125, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI145693175, Length=275, Percent_Identity=26.5454545454545, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 59047; Mature: 59047

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCEEEHHHHHHCCHHCCCCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure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HHHHHCCCCCCCEEEHHHHHHCCHHCCCCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]