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The map label for this gene is cdd

Identifier: 157369811

GI number: 157369811

Start: 1709937

End: 1710821

Strand: Reverse

Name: cdd

Synonym: Spro_1568

Alternate gene names: 157369811

Gene position: 1710821-1709937 (Counterclockwise)

Preceding gene: 157369812

Following gene: 157369810

Centisome position: 31.4

GC content: 59.55

Gene sequence:

>885_bases
ATGCACCCGCGTTTTCAAACCGCTTTTGGCGAACTGCCCGCCACCTTGCAATCCGCCCTGCAGTCTTATATTGATGCGCC
TGATTTCCCGGCCATGCTCAAGGCGGAACAAGTGGACGCGATCACGCAGCGCTGCGGGCTGGATGATGATGCTCTGGCAT
TCGCTCTGCTGCCACTGGCGGCGGCCTGCTCGTTAGCGCCAATCTCACAATTTTATGTCGGTGCCATTGCCCGTGGGCAG
AGCGGCAATCTGTATTTTGGTGCCAATATGGAATTCAGCGGCGCCCCGATGCAACAAACCATTCATGCGGAACAGTGTGC
GGTGACCCACGCCTGGCTGCGCGGTGAGCCCGCCCTGGCCTCCATCACCGTTAACTACACGCCTTGCGGCCACTGCCGTC
AGTTTATGAACGAACTGAACAGCGGCGTCAGCCTTAAAATTCGTCTGCCCGGCCGTGAACCGGCAACGCTTGGCGATTAC
CTGCCGGACTCCTTCGGCCCGAAAGACCTGGATATCACCACGCTGCTGATGGACCAGGTCGATCATGGTTTCCAACTGGC
GCTGACTGACGAACTGGAAAAAGCAGCGCTGGCCGCTGCCAATCAGAGCCACGCGCCCTACAGCAACGCCCACAGCGGCG
TCGCACTGGAGGCTGAAGACGGCACAGTCTACACTGGCCGTTATGCGGAAAACGCCGCCTTCAACCCAAGTCTGCCGCCC
CTGCAGGCCGCGCTGATTCTGATGAATGTTTCCGGCGACGACTGTCAAAAGGTGAAGCGCGCCGTGCTGGCTGAGCCAGA
AAGTGCCATCCTCACCCAATGGGATGCTACCCGTGCCACGCTGGCTGCCCTGGGCTGCCAAAATGTCAGCCGCATTACTT
TCTGA

Upstream 100 bases:

>100_bases
TTTCATTGCATTGATTTCATCAATAAAGAGATTTACATCACACTTTATTCACGCAAGGCTGCCTAGAATGTTATCCCGTT
AACCTGTAGAGAGAGTTTCT

Downstream 100 bases:

>100_bases
TCCTGACCCTGGCGGTGCTGCCCGGCACCGCTATTAACAGCCCCGCCAGCCAAATACAATGGCATTCACGTCTTAAAACA
CTTTCTTTAGTTAAATTAGG

Product: cytidine deaminase

Products: NA

Alternate protein names: Cytidine aminohydrolase; CDA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MHPRFQTAFGELPATLQSALQSYIDAPDFPAMLKAEQVDAITQRCGLDDDALAFALLPLAAACSLAPISQFYVGAIARGQ
SGNLYFGANMEFSGAPMQQTIHAEQCAVTHAWLRGEPALASITVNYTPCGHCRQFMNELNSGVSLKIRLPGREPATLGDY
LPDSFGPKDLDITTLLMDQVDHGFQLALTDELEKAALAAANQSHAPYSNAHSGVALEAEDGTVYTGRYAENAAFNPSLPP
LQAALILMNVSGDDCQKVKRAVLAEPESAILTQWDATRATLAALGCQNVSRITF

Sequences:

>Translated_294_residues
MHPRFQTAFGELPATLQSALQSYIDAPDFPAMLKAEQVDAITQRCGLDDDALAFALLPLAAACSLAPISQFYVGAIARGQ
SGNLYFGANMEFSGAPMQQTIHAEQCAVTHAWLRGEPALASITVNYTPCGHCRQFMNELNSGVSLKIRLPGREPATLGDY
LPDSFGPKDLDITTLLMDQVDHGFQLALTDELEKAALAAANQSHAPYSNAHSGVALEAEDGTVYTGRYAENAAFNPSLPP
LQAALILMNVSGDDCQKVKRAVLAEPESAILTQWDATRATLAALGCQNVSRITF
>Mature_294_residues
MHPRFQTAFGELPATLQSALQSYIDAPDFPAMLKAEQVDAITQRCGLDDDALAFALLPLAAACSLAPISQFYVGAIARGQ
SGNLYFGANMEFSGAPMQQTIHAEQCAVTHAWLRGEPALASITVNYTPCGHCRQFMNELNSGVSLKIRLPGREPATLGDY
LPDSFGPKDLDITTLLMDQVDHGFQLALTDELEKAALAAANQSHAPYSNAHSGVALEAEDGTVYTGRYAENAAFNPSLPP
LQAALILMNVSGDDCQKVKRAVLAEPESAILTQWDATRATLAALGCQNVSRITF

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Escherichia coli, GI1788465, Length=292, Percent_Identity=66.0958904109589, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDD_SERP5 (A8GC32)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477800.1
- ProteinModelPortal:   A8GC32
- SMR:   A8GC32
- STRING:   A8GC32
- GeneID:   5602890
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1568
- eggNOG:   COG0295
- HOGENOM:   HBG591160
- OMA:   NRSHAPY
- ProtClustDB:   PRK09027
- BioCyc:   SPRO399741:SPRO_1568-MONOMER
- HAMAP:   MF_01558
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013171
- InterPro:   IPR006263
- InterPro:   IPR016193
- InterPro:   IPR020797
- PIRSF:   PIRSF006334
- TIGRFAMs:   TIGR01355

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF08211 dCMP_cyt_deam_2; SSF53927 Cytidine_deaminase-like

EC number: =3.5.4.5

Molecular weight: Translated: 31458; Mature: 31458

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPRFQTAFGELPATLQSALQSYIDAPDFPAMLKAEQVDAITQRCGLDDDALAFALLPLA
CCCCHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AACSLAPISQFYVGAIARGQSGNLYFGANMEFSGAPMQQTIHAEQCAVTHAWLRGEPALA
HHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
SITVNYTPCGHCRQFMNELNSGVSLKIRLPGREPATLGDYLPDSFGPKDLDITTLLMDQV
EEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHC
DHGFQLALTDELEKAALAAANQSHAPYSNAHSGVALEAEDGTVYTGRYAENAAFNPSLPP
CCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCH
LQAALILMNVSGDDCQKVKRAVLAEPESAILTQWDATRATLAALGCQNVSRITF
HEEEEEEEECCCHHHHHHHHHHHCCCCHHHEECCCHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure
MHPRFQTAFGELPATLQSALQSYIDAPDFPAMLKAEQVDAITQRCGLDDDALAFALLPLA
CCCCHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AACSLAPISQFYVGAIARGQSGNLYFGANMEFSGAPMQQTIHAEQCAVTHAWLRGEPALA
HHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
SITVNYTPCGHCRQFMNELNSGVSLKIRLPGREPATLGDYLPDSFGPKDLDITTLLMDQV
EEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHC
DHGFQLALTDELEKAALAAANQSHAPYSNAHSGVALEAEDGTVYTGRYAENAAFNPSLPP
CCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCH
LQAALILMNVSGDDCQKVKRAVLAEPESAILTQWDATRATLAALGCQNVSRITF
HEEEEEEEECCCHHHHHHHHHHHCCCCHHHEECCCHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA