Click here to switch to the map view.

The map label for this gene is resE [H]

Identifier: 157369750

GI number: 157369750

Start: 1642319

End: 1643785

Strand: Reverse

Name: resE [H]

Synonym: Spro_1507

Alternate gene names: 157369750

Gene position: 1643785-1642319 (Counterclockwise)

Preceding gene: 157369751

Following gene: 157369740

Centisome position: 30.17

GC content: 59.17

Gene sequence:

>1467_bases
ATGAAAAATCTTACGCTAACGCAACGTCTGACCCTGATCTTCGCCCTGTTGATGGTAGTCAGCTGCGCCATCTCCGGCTG
GATGCAGGTGCGCAGCAGCACCCAGTACAGCCAGACGGTGATCCAACGGCTGTCCGGTAATCTGGCGCAGCACATTGCCG
ACAGTAACCCGCTGTTGGGGCAAAACGGGCTGAACGCGCAGTCGGTGCAAAACCTGTTCGGTCAACTGATGGCGGTGAAT
CCCAGCGTTGAGGTTTATCTGCTCGATAAGCAGGGTGAGATTATCGGCAACGCCGCACCGGCCGGTCACCTGAAACGCCA
GAAGGTCGATCTGCTGCCGCTGCAGGCGCTCTTTAATGGTGCAAATATGCCGGTTTACGGCGATGACCCGCGTAATCCGG
ATGCCAAAAAAGTGTTCAGCGCCGCGCCCCTGAAGGTCAACGGTCAGGTTGAGGGCTACCTGTACGTGGTTTTGCTGGGC
GAGGATTACGACGCGTTAACCAGTCATGCTTTGCATAACTCCGCAGTCTCCATGGCGCTGTGGACCTCGGGCCTGATGGT
GCTATTTAGTCTGGTGGCCGGTGGTTTTGCATTTTATTGGGTGACCCGACCTATCCGCCGTTTGACACGTCAGGTCAGTG
AGTTGGACAGCGGTGGCATCGCGGCAGTACAAGCCTATGCGGCACTGCCAGCCGACAGCGGCGGTCGCGATGAAGTCAGC
CGACTGCAGCAGGCATTCCGCAGCATGGCGCAGCGTATCGCCGAACAGTGGCAGACGCTTTCGCAGCAGGATCAGCAACG
CCGTGAGTTCATCGCCAACATCTCGCACGATCTGCGCACTCCCCTGACGTCGTTGCACGGCTACCTGGAAACGCTATCGG
TTAAATCGGCCAGCCTGAGCGACAACGATCGCCAACGCTATCTGGAGATTGCACTGGCGCAGAGCCGTAAGGTCGGCCGA
TTGGCGCAGGAACTGTTCGAGCTGGCGCGACTGGAGTATGGCGTGGTGAAACCGCAGAAGGAGCCGTTCTCGCTCAGCGA
ATTGGTGCAGGACGTGTTCCAGAAGTTCGAATTGGCAGCAGAGGCTCGCCAGCAAAGGCTGCTGGCGGATATTACCCCCG
GCATTCCGTTGGTGTTTGCCGATGTCAGTATGATTGAGCGGGTACTGACCAACCTGCTGGACAACGCCATCCGCCACACG
CCGCAGGGCGGTGAGATTGAAGTGCGCCTGTGGCAACAGGCAGGCAAGGTGCTGGTGCAGGTTAATGACAGCGGCCCGGG
CATCCCGCAGGAACTACGCGCCGATCTGTTCGTGCGCCCTTCGATTCTGAGCAGCGCCCGCCGCCATGCCAGCGGGTTGG
GACTGATGATCGTTCGGCGCATTTTGCTGCTGCACGACAGCGATATCCAACTGGTCGAGCGGCCGCAAACCGGTGCCTGT
TTCCGCTTTTCGATCCCGCTGCGTTAG

Upstream 100 bases:

>100_bases
GCTGCGTATCAAGATCGAAACCAATCCGGCGGAACCCGAGCGCATCCTCACCGTGTGGGGCATGGGCTATAAATTCGCGG
CGGTGCCGCAAGAGTAAACC

Downstream 100 bases:

>100_bases
TTAATGCAGCTTTTATCGACGCTGATAAATTTGTCGTTATAAATAATAAATTTCTGCCCTTTCAGCCGAATGCCTGCATG
GGTCAGCGTATCACCCGGGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MKNLTLTQRLTLIFALLMVVSCAISGWMQVRSSTQYSQTVIQRLSGNLAQHIADSNPLLGQNGLNAQSVQNLFGQLMAVN
PSVEVYLLDKQGEIIGNAAPAGHLKRQKVDLLPLQALFNGANMPVYGDDPRNPDAKKVFSAAPLKVNGQVEGYLYVVLLG
EDYDALTSHALHNSAVSMALWTSGLMVLFSLVAGGFAFYWVTRPIRRLTRQVSELDSGGIAAVQAYAALPADSGGRDEVS
RLQQAFRSMAQRIAEQWQTLSQQDQQRREFIANISHDLRTPLTSLHGYLETLSVKSASLSDNDRQRYLEIALAQSRKVGR
LAQELFELARLEYGVVKPQKEPFSLSELVQDVFQKFELAAEARQQRLLADITPGIPLVFADVSMIERVLTNLLDNAIRHT
PQGGEIEVRLWQQAGKVLVQVNDSGPGIPQELRADLFVRPSILSSARRHASGLGLMIVRRILLLHDSDIQLVERPQTGAC
FRFSIPLR

Sequences:

>Translated_488_residues
MKNLTLTQRLTLIFALLMVVSCAISGWMQVRSSTQYSQTVIQRLSGNLAQHIADSNPLLGQNGLNAQSVQNLFGQLMAVN
PSVEVYLLDKQGEIIGNAAPAGHLKRQKVDLLPLQALFNGANMPVYGDDPRNPDAKKVFSAAPLKVNGQVEGYLYVVLLG
EDYDALTSHALHNSAVSMALWTSGLMVLFSLVAGGFAFYWVTRPIRRLTRQVSELDSGGIAAVQAYAALPADSGGRDEVS
RLQQAFRSMAQRIAEQWQTLSQQDQQRREFIANISHDLRTPLTSLHGYLETLSVKSASLSDNDRQRYLEIALAQSRKVGR
LAQELFELARLEYGVVKPQKEPFSLSELVQDVFQKFELAAEARQQRLLADITPGIPLVFADVSMIERVLTNLLDNAIRHT
PQGGEIEVRLWQQAGKVLVQVNDSGPGIPQELRADLFVRPSILSSARRHASGLGLMIVRRILLLHDSDIQLVERPQTGAC
FRFSIPLR
>Mature_488_residues
MKNLTLTQRLTLIFALLMVVSCAISGWMQVRSSTQYSQTVIQRLSGNLAQHIADSNPLLGQNGLNAQSVQNLFGQLMAVN
PSVEVYLLDKQGEIIGNAAPAGHLKRQKVDLLPLQALFNGANMPVYGDDPRNPDAKKVFSAAPLKVNGQVEGYLYVVLLG
EDYDALTSHALHNSAVSMALWTSGLMVLFSLVAGGFAFYWVTRPIRRLTRQVSELDSGGIAAVQAYAALPADSGGRDEVS
RLQQAFRSMAQRIAEQWQTLSQQDQQRREFIANISHDLRTPLTSLHGYLETLSVKSASLSDNDRQRYLEIALAQSRKVGR
LAQELFELARLEYGVVKPQKEPFSLSELVQDVFQKFELAAEARQQRLLADITPGIPLVFADVSMIERVLTNLLDNAIRHT
PQGGEIEVRLWQQAGKVLVQVNDSGPGIPQELRADLFVRPSILSSARRHASGLGLMIVRRILLLHDSDIQLVERPQTGAC
FRFSIPLR

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=33.0543933054393, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790861, Length=462, Percent_Identity=25.974025974026, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788713, Length=305, Percent_Identity=27.5409836065574, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=290, Percent_Identity=28.6206896551724, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=30.9012875536481, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=28.099173553719, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786783, Length=509, Percent_Identity=24.3614931237721, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI87081816, Length=321, Percent_Identity=28.0373831775701, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082128, Length=310, Percent_Identity=26.1290322580645, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789149, Length=355, Percent_Identity=25.9154929577465, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=26.6393442622951, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790551, Length=307, Percent_Identity=26.7100977198697, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=25.5060728744939, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=25.6302521008403, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790300, Length=257, Percent_Identity=26.8482490272374, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788279, Length=263, Percent_Identity=24.3346007604563, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=274, Percent_Identity=29.9270072992701, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787374, Length=267, Percent_Identity=24.3445692883895, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54026; Mature: 54026

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLTLTQRLTLIFALLMVVSCAISGWMQVRSSTQYSQTVIQRLSGNLAQHIADSNPLLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
QNGLNAQSVQNLFGQLMAVNPSVEVYLLDKQGEIIGNAAPAGHLKRQKVDLLPLQALFNG
CCCCCHHHHHHHHHHHEEECCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHCC
ANMPVYGDDPRNPDAKKVFSAAPLKVNGQVEGYLYVVLLGEDYDALTSHALHNSAVSMAL
CCCCCCCCCCCCCCHHHHHCCCCEEECCEECEEEEEEEECCCHHHHHHHHHHHHHHHHHH
WTSGLMVLFSLVAGGFAFYWVTRPIRRLTRQVSELDSGGIAAVQAYAALPADSGGRDEVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHH
RLQQAFRSMAQRIAEQWQTLSQQDQQRREFIANISHDLRTPLTSLHGYLETLSVKSASLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DNDRQRYLEIALAQSRKVGRLAQELFELARLEYGVVKPQKEPFSLSELVQDVFQKFELAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
EARQQRLLADITPGIPLVFADVSMIERVLTNLLDNAIRHTPQGGEIEVRLWQQAGKVLVQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEE
VNDSGPGIPQELRADLFVRPSILSSARRHASGLGLMIVRRILLLHDSDIQLVERPQTGAC
ECCCCCCCCHHHHHHHEECHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCE
FRFSIPLR
EEEECCCC
>Mature Secondary Structure
MKNLTLTQRLTLIFALLMVVSCAISGWMQVRSSTQYSQTVIQRLSGNLAQHIADSNPLLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
QNGLNAQSVQNLFGQLMAVNPSVEVYLLDKQGEIIGNAAPAGHLKRQKVDLLPLQALFNG
CCCCCHHHHHHHHHHHEEECCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHCC
ANMPVYGDDPRNPDAKKVFSAAPLKVNGQVEGYLYVVLLGEDYDALTSHALHNSAVSMAL
CCCCCCCCCCCCCCHHHHHCCCCEEECCEECEEEEEEEECCCHHHHHHHHHHHHHHHHHH
WTSGLMVLFSLVAGGFAFYWVTRPIRRLTRQVSELDSGGIAAVQAYAALPADSGGRDEVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHH
RLQQAFRSMAQRIAEQWQTLSQQDQQRREFIANISHDLRTPLTSLHGYLETLSVKSASLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DNDRQRYLEIALAQSRKVGRLAQELFELARLEYGVVKPQKEPFSLSELVQDVFQKFELAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
EARQQRLLADITPGIPLVFADVSMIERVLTNLLDNAIRHTPQGGEIEVRLWQQAGKVLVQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEE
VNDSGPGIPQELRADLFVRPSILSSARRHASGLGLMIVRRILLLHDSDIQLVERPQTGAC
ECCCCCCCCHHHHHHHEECHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCE
FRFSIPLR
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]