Click here to switch to the map view.

The map label for this gene is can [H]

Identifier: 157369660

GI number: 157369660

Start: 1544945

End: 1545556

Strand: Reverse

Name: can [H]

Synonym: Spro_1417

Alternate gene names: 157369660

Gene position: 1545556-1544945 (Counterclockwise)

Preceding gene: 157369671

Following gene: 157369659

Centisome position: 28.36

GC content: 54.58

Gene sequence:

>612_bases
ATGACAACGATTAATCATCTGCTGGTAAAAAACCGCAGTTGGGCAACTCAGCAACAATCCCGCGATCCCAATTTCTTCCC
GCAGTTGGCACAGGCGCAGAAACCGCACATTCTGTGGATTGGCTGCTCCGACAGCCGGGTTCCCGCCGAAACTATTGTGC
GTGCACAACCCGGCGAGCTGTTTGTACACCGCAATATCGCCAACGTGGTCGAAGAGCAGGATGATAATTTGATGAGCGTG
GTGCAATACGCGGTCGAACATCTGGAGGTCGGGGCCATCGTGATTTGCGGGCATTACGGTTGCGGTGGGATCCAGGCGGC
CCTGAGCAGCCGTAACACCCCCAGTAAGGATTCACTCACACGCCGTCTCAATTCGCTACGTGCCAAACTGGAGCCACATT
TGCCGGCTGAGACCGATACCCATGACGACGACCTGAATAAAGCAGCCCACGCCAACGTACAGCTCCAGCTCAATACCCTC
AGCAAAACCCAGTTAATACAACGCGCCTGGCGACACAATGCCGGGTTAACGCTGGTCGGTTGTATTTACGACATGCATAC
CGGATTTTTAAACGTACTGGAACAGCGCAACGCTGCCGGGAGGATGACATGA

Upstream 100 bases:

>100_bases
ATTGGACTAACCTTGGACAGGAGTTTTTTGCTAGTGGCGACGGCCTGCACGTCAGCGCCGAACTTTCTCGCTGCCAAATC
CCCTGACCCAAGGAGCTTTC

Downstream 100 bases:

>100_bases
ATCGTGCCGATCTGCGTTTTGACCTGCCCGCCGGGCTGGTGGTGTTTCTGGTCGCCCTGCCGCTCAGTCTGGGCATTGCA
CAAGCCAGCGGCGTACCGCC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTTINHLLVKNRSWATQQQSRDPNFFPQLAQAQKPHILWIGCSDSRVPAETIVRAQPGELFVHRNIANVVEEQDDNLMSV
VQYAVEHLEVGAIVICGHYGCGGIQAALSSRNTPSKDSLTRRLNSLRAKLEPHLPAETDTHDDDLNKAAHANVQLQLNTL
SKTQLIQRAWRHNAGLTLVGCIYDMHTGFLNVLEQRNAAGRMT

Sequences:

>Translated_203_residues
MTTINHLLVKNRSWATQQQSRDPNFFPQLAQAQKPHILWIGCSDSRVPAETIVRAQPGELFVHRNIANVVEEQDDNLMSV
VQYAVEHLEVGAIVICGHYGCGGIQAALSSRNTPSKDSLTRRLNSLRAKLEPHLPAETDTHDDDLNKAAHANVQLQLNTL
SKTQLIQRAWRHNAGLTLVGCIYDMHTGFLNVLEQRNAAGRMT
>Mature_202_residues
TTINHLLVKNRSWATQQQSRDPNFFPQLAQAQKPHILWIGCSDSRVPAETIVRAQPGELFVHRNIANVVEEQDDNLMSVV
QYAVEHLEVGAIVICGHYGCGGIQAALSSRNTPSKDSLTRRLNSLRAKLEPHLPAETDTHDDDLNKAAHANVQLQLNTLS
KTQLIQRAWRHNAGLTLVGCIYDMHTGFLNVLEQRNAAGRMT

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=200, Percent_Identity=43.5, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1786534, Length=179, Percent_Identity=34.0782122905028, Blast_Score=84, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324292, Length=191, Percent_Identity=30.3664921465969, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 22632; Mature: 22501

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTINHLLVKNRSWATQQQSRDPNFFPQLAQAQKPHILWIGCSDSRVPAETIVRAQPGEL
CCCHHHHHHCCCCCCCHHHCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVHRNIANVVEEQDDNLMSVVQYAVEHLEVGAIVICGHYGCGGIQAALSSRNTPSKDSLT
EEECHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCCHHHHH
RRLNSLRAKLEPHLPAETDTHDDDLNKAAHANVQLQLNTLSKTQLIQRAWRHNAGLTLVG
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCCEEEH
CIYDMHTGFLNVLEQRNAAGRMT
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTINHLLVKNRSWATQQQSRDPNFFPQLAQAQKPHILWIGCSDSRVPAETIVRAQPGEL
CCHHHHHHCCCCCCCHHHCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVHRNIANVVEEQDDNLMSVVQYAVEHLEVGAIVICGHYGCGGIQAALSSRNTPSKDSLT
EEECHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCCHHHHH
RRLNSLRAKLEPHLPAETDTHDDDLNKAAHANVQLQLNTLSKTQLIQRAWRHNAGLTLVG
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCCEEEH
CIYDMHTGFLNVLEQRNAAGRMT
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]