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The map label for this gene is ycaN [H]

Identifier: 157369422

GI number: 157369422

Start: 1296631

End: 1297542

Strand: Direct

Name: ycaN [H]

Synonym: Spro_1179

Alternate gene names: 157369422

Gene position: 1296631-1297542 (Clockwise)

Preceding gene: 157369420

Following gene: 157369423

Centisome position: 23.8

GC content: 59.87

Gene sequence:

>912_bases
ATGAGAGGAAGTGATTTCGCGGAATTACGCGCTTTTGCCGTCATTGTTGAGCATGGCAGCTTTACCCGTGCCGCAGCGCA
ATTGGGCATCTCCGCCTCAGCGCTTAGTCAGACGCAGCGCAATCTGGAAACCCGGCTGGGTGTACGTCTGCTGAATCGCA
CCACGCGAAGTGTCGCGCTGACCCAAGCGGGGGAATTGCTGTTGGCGCGTTTATCACCGGCAATGGCCGAGATTGAAGCC
GCCGTGACGCAGACCGCCGCGCTGCGTTTGCAGCCGGCGGGCACCCTACGGCTTAATGCATCCGGCCTGGCGGCGATCCA
TTATTTGGCTCCGCTGTTGGCTCCGTTCAATGCGCATTATCCCGATATTGTTGTGGATCTGAGCGTGGAGGATCGGCTGG
TGGATATGGTAGCCGCGGGTTTTGATGCGGGTGTGCGGCTGCATGAGCGACTGGAGAAGGATATGGTGGCCGTCGCGCTG
GGGGGCGAGCAACGAATGTGCGTGGTAGCCTCGCCAGCCTATTTGGCGCGTTATGGCACGCCGCAAACCCCCGATGCGCT
ACGTCAGCACCGCTGCCTGAATACTCGCTGGCCAACCAATGGCAGTATTTATCGTTGGGAATTCGAGCGCGGTGGCGAAA
AGCTGGAAATCGCGGTGGAGGGGCCGTTGATTGTGGATGAACCGCAGGTGCTGGTGCGTGCCGCTGCGGATGGATTGGGG
ATTGCCTATCTGTTTGAGAGTCAGGTGGCAGAGGCATTGAACGACGGCCGATTGCTGCCGTTACTGGCGGCCTGGACGCC
ACCGTTTCCCGGTTTCTATCTTTATTACCCCGCCAACCGGCAAATGCCGCGTCCGCTGCGCGCGTTTATTGATTTCGCCC
GGCAGCAGAGCCCACAGGCAATTGGCGCATGA

Upstream 100 bases:

>100_bases
CATGGGGTATTTCCTCTATGGTTTTGTTCAAGCATAGGCCCCACCGGGAGTGTAATGAATACGCTATAATCTTCATGAAT
TATTAAGTGTAGGGGGCATA

Downstream 100 bases:

>100_bases
ATACCGCCCGGTTTTTTTGAATAACTCTGTCAGATAAATTTGGTATTCACCCCAGGGTCAGTTGATTAGATTGGATAAGA
ATATCCTCGGGTGCCGTCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MRGSDFAELRAFAVIVEHGSFTRAAAQLGISASALSQTQRNLETRLGVRLLNRTTRSVALTQAGELLLARLSPAMAEIEA
AVTQTAALRLQPAGTLRLNASGLAAIHYLAPLLAPFNAHYPDIVVDLSVEDRLVDMVAAGFDAGVRLHERLEKDMVAVAL
GGEQRMCVVASPAYLARYGTPQTPDALRQHRCLNTRWPTNGSIYRWEFERGGEKLEIAVEGPLIVDEPQVLVRAAADGLG
IAYLFESQVAEALNDGRLLPLLAAWTPPFPGFYLYYPANRQMPRPLRAFIDFARQQSPQAIGA

Sequences:

>Translated_303_residues
MRGSDFAELRAFAVIVEHGSFTRAAAQLGISASALSQTQRNLETRLGVRLLNRTTRSVALTQAGELLLARLSPAMAEIEA
AVTQTAALRLQPAGTLRLNASGLAAIHYLAPLLAPFNAHYPDIVVDLSVEDRLVDMVAAGFDAGVRLHERLEKDMVAVAL
GGEQRMCVVASPAYLARYGTPQTPDALRQHRCLNTRWPTNGSIYRWEFERGGEKLEIAVEGPLIVDEPQVLVRAAADGLG
IAYLFESQVAEALNDGRLLPLLAAWTPPFPGFYLYYPANRQMPRPLRAFIDFARQQSPQAIGA
>Mature_303_residues
MRGSDFAELRAFAVIVEHGSFTRAAAQLGISASALSQTQRNLETRLGVRLLNRTTRSVALTQAGELLLARLSPAMAEIEA
AVTQTAALRLQPAGTLRLNASGLAAIHYLAPLLAPFNAHYPDIVVDLSVEDRLVDMVAAGFDAGVRLHERLEKDMVAVAL
GGEQRMCVVASPAYLARYGTPQTPDALRQHRCLNTRWPTNGSIYRWEFERGGEKLEIAVEGPLIVDEPQVLVRAAADGLG
IAYLFESQVAEALNDGRLLPLLAAWTPPFPGFYLYYPANRQMPRPLRAFIDFARQQSPQAIGA

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=294, Percent_Identity=44.8979591836735, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=40.5498281786942, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=34.3434343434343, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=33.6805555555556, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=28.5234899328859, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=30.9278350515464, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=27.4305555555556, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786448, Length=283, Percent_Identity=27.5618374558304, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788706, Length=299, Percent_Identity=25.0836120401338, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=173, Percent_Identity=35.2601156069364, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788748, Length=118, Percent_Identity=36.4406779661017, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790011, Length=269, Percent_Identity=24.1635687732342, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=145, Percent_Identity=32.4137931034483, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=121, Percent_Identity=29.7520661157025, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786713, Length=276, Percent_Identity=27.536231884058, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33042; Mature: 33042

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGSDFAELRAFAVIVEHGSFTRAAAQLGISASALSQTQRNLETRLGVRLLNRTTRSVAL
CCCCHHHHHHEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQAGELLLARLSPAMAEIEAAVTQTAALRLQPAGTLRLNASGLAAIHYLAPLLAPFNAHY
HHHHHHHHHHHCHHHHHHHHHHHHHHHEEECCCCEEEECCCCHHHHHHHHHHHCCCCCCC
PDIVVDLSVEDRLVDMVAAGFDAGVRLHERLEKDMVAVALGGEQRMCVVASPAYLARYGT
CCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHCEEEEEECCCCEEEEEECCHHHHHCCC
PQTPDALRQHRCLNTRWPTNGSIYRWEFERGGEKLEIAVEGPLIVDEPQVLVRAAADGLG
CCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCEEECCCHHHHHHHCCCCE
IAYLFESQVAEALNDGRLLPLLAAWTPPFPGFYLYYPANRQMPRPLRAFIDFARQQSPQA
EEHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCC
IGA
CCC
>Mature Secondary Structure
MRGSDFAELRAFAVIVEHGSFTRAAAQLGISASALSQTQRNLETRLGVRLLNRTTRSVAL
CCCCHHHHHHEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQAGELLLARLSPAMAEIEAAVTQTAALRLQPAGTLRLNASGLAAIHYLAPLLAPFNAHY
HHHHHHHHHHHCHHHHHHHHHHHHHHHEEECCCCEEEECCCCHHHHHHHHHHHCCCCCCC
PDIVVDLSVEDRLVDMVAAGFDAGVRLHERLEKDMVAVALGGEQRMCVVASPAYLARYGT
CCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHCEEEEEECCCCEEEEEECCHHHHHCCC
PQTPDALRQHRCLNTRWPTNGSIYRWEFERGGEKLEIAVEGPLIVDEPQVLVRAAADGLG
CCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCEEECCCHHHHHHHCCCCE
IAYLFESQVAEALNDGRLLPLLAAWTPPFPGFYLYYPANRQMPRPLRAFIDFARQQSPQA
EEHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCC
IGA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]