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The map label for this gene is cfa [H]

Identifier: 157369397

GI number: 157369397

Start: 1270207

End: 1271358

Strand: Direct

Name: cfa [H]

Synonym: Spro_1154

Alternate gene names: 157369397

Gene position: 1270207-1271358 (Clockwise)

Preceding gene: 157369394

Following gene: 157369401

Centisome position: 23.31

GC content: 54.34

Gene sequence:

>1152_bases
ATGGACTCAATCAGTGTTGATGAACTCGCCCCAAAAAAAGATCGTTGGTATCGCATTGTGGAGGAATTACTGTCCGCTGC
CGGTATTGCCATCAATGGCAACCGTGCCTGCGATATCAAGGTACACAACCCGGCGTTGTTTAAACGTATTTTGCAGGAGG
GGTCGCTGGGGTTCGGCGAAAGCTACATGGACGGCTGGTGGGACTGCGAGCGGTTGGACGCATTATTTACCCGCGTCCTG
CAGGCCGGCGTTGATGAACGTTTGCCAAAAAATCTGAGCGACATTGCGCGCATCGCCTATACCCGGCTGTTCAACCTTCA
GTCACGCAAACGCGCCTGGCAGGTGGGTAAAGAACATTACGATATCGGCAACGATCTGTTCCGTGCGATGCTCGATCCCT
ATATGCAATATTCCTGCGGTTACTGGAAAGAGGCCGATACGCTGGAGCAGGCGCAGTTGGCCAAGCTGAAAATGATCTGC
GAGAAACTGCAGTTGAAACCGGGCATGTCGTTGCTGGATATCGGCTGCGGCTGGGGTGGGCTGGCGCAGTATGCCGCGGA
AAACTACGGCGTAACAGTGCATGGTGTGACCATTTCCGCCGAGCAGCAAAAACTGGCGCAGGAGCGCTGCGCCGGTCTTG
AGGTCGAAATTGTGCTGCAGGATTACCGTGACTTGAACCGCCAGTTTGATCGTATTGTTTCAGTCGGCATGTTTGAACAC
GTGGGGCCGAAAAACTACGACACTTACTTCCGTGTTGCCGCGCGTAATCTTAAGCCCGACGGTTTGTTCCTGCTGCACAC
CATTGGCGCCAACCAAACCAATCTTCACGTCGATGCCTGGATAAACAAGTACATCTTCCCCAATGGCTGTCTGCCTTCGG
TGCGCCATATTGCCCAAGCCAGCGAAGGGCGCTTTGTGATGGAAGATTGGCACAATATCGGCGCCGATTACGATCGCACG
CTGATGGCCTGGTATGAGAATTTCAAACAGGCGTGGCCGATGCTGTCCGAGGGCTATTCTGAACGTTTCGAGCGGATGTT
CACCTATTACCTGAACGCCTGCGCCGGAGCATTCCGCTCGCGTGATATTCAGCTGTGGCAGGTGTTGTTCAGCCCGAAAG
GCGTTGAAGGTGGGGCACGGGTTTACCGTTGA

Upstream 100 bases:

>100_bases
TCTTGGCTAGAGTAAAAAGCATTGCCGTTTTTCACTTCGAATATTTGTCATTTTTATTTGCGACTATGCTTTTTGAAATG
ACATTTCTCCAAGGATTGTT

Downstream 100 bases:

>100_bases
GAAGGGAGGGGCGCAGCGGACTACGCCCCGAACTATCAGTACAACAGCGAATACAGCTGGCGGCGGTATTTGGCGGCCAG
CGCATCGCCGGTGCCCAGTG

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MDSISVDELAPKKDRWYRIVEELLSAAGIAINGNRACDIKVHNPALFKRILQEGSLGFGESYMDGWWDCERLDALFTRVL
QAGVDERLPKNLSDIARIAYTRLFNLQSRKRAWQVGKEHYDIGNDLFRAMLDPYMQYSCGYWKEADTLEQAQLAKLKMIC
EKLQLKPGMSLLDIGCGWGGLAQYAAENYGVTVHGVTISAEQQKLAQERCAGLEVEIVLQDYRDLNRQFDRIVSVGMFEH
VGPKNYDTYFRVAARNLKPDGLFLLHTIGANQTNLHVDAWINKYIFPNGCLPSVRHIAQASEGRFVMEDWHNIGADYDRT
LMAWYENFKQAWPMLSEGYSERFERMFTYYLNACAGAFRSRDIQLWQVLFSPKGVEGGARVYR

Sequences:

>Translated_383_residues
MDSISVDELAPKKDRWYRIVEELLSAAGIAINGNRACDIKVHNPALFKRILQEGSLGFGESYMDGWWDCERLDALFTRVL
QAGVDERLPKNLSDIARIAYTRLFNLQSRKRAWQVGKEHYDIGNDLFRAMLDPYMQYSCGYWKEADTLEQAQLAKLKMIC
EKLQLKPGMSLLDIGCGWGGLAQYAAENYGVTVHGVTISAEQQKLAQERCAGLEVEIVLQDYRDLNRQFDRIVSVGMFEH
VGPKNYDTYFRVAARNLKPDGLFLLHTIGANQTNLHVDAWINKYIFPNGCLPSVRHIAQASEGRFVMEDWHNIGADYDRT
LMAWYENFKQAWPMLSEGYSERFERMFTYYLNACAGAFRSRDIQLWQVLFSPKGVEGGARVYR
>Mature_383_residues
MDSISVDELAPKKDRWYRIVEELLSAAGIAINGNRACDIKVHNPALFKRILQEGSLGFGESYMDGWWDCERLDALFTRVL
QAGVDERLPKNLSDIARIAYTRLFNLQSRKRAWQVGKEHYDIGNDLFRAMLDPYMQYSCGYWKEADTLEQAQLAKLKMIC
EKLQLKPGMSLLDIGCGWGGLAQYAAENYGVTVHGVTISAEQQKLAQERCAGLEVEIVLQDYRDLNRQFDRIVSVGMFEH
VGPKNYDTYFRVAARNLKPDGLFLLHTIGANQTNLHVDAWINKYIFPNGCLPSVRHIAQASEGRFVMEDWHNIGADYDRT
LMAWYENFKQAWPMLSEGYSERFERMFTYYLNACAGAFRSRDIQLWQVLFSPKGVEGGARVYR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=383, Percent_Identity=73.6292428198433, Blast_Score=602, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI133904226, Length=377, Percent_Identity=30.2387267904509, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 43980; Mature: 43980

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSISVDELAPKKDRWYRIVEELLSAAGIAINGNRACDIKVHNPALFKRILQEGSLGFGE
CCCCCCHHCCCCHHHHHHHHHHHHHHCCEEECCCEEEEEEECCHHHHHHHHHHCCCCCCH
SYMDGWWDCERLDALFTRVLQAGVDERLPKNLSDIARIAYTRLFNLQSRKRAWQVGKEHY
HHHCCCCCHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DIGNDLFRAMLDPYMQYSCGYWKEADTLEQAQLAKLKMICEKLQLKPGMSLLDIGCGWGG
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHH
LAQYAAENYGVTVHGVTISAEQQKLAQERCAGLEVEIVLQDYRDLNRQFDRIVSVGMFEH
HHHHHHHCCCEEEEEEEECHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VGPKNYDTYFRVAARNLKPDGLFLLHTIGANQTNLHVDAWINKYIFPNGCLPSVRHIAQA
CCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCEEHHHHHHHCCCCCCCCHHHHHHHHH
SEGRFVMEDWHNIGADYDRTLMAWYENFKQAWPMLSEGYSERFERMFTYYLNACAGAFRS
CCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDIQLWQVLFSPKGVEGGARVYR
CCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDSISVDELAPKKDRWYRIVEELLSAAGIAINGNRACDIKVHNPALFKRILQEGSLGFGE
CCCCCCHHCCCCHHHHHHHHHHHHHHCCEEECCCEEEEEEECCHHHHHHHHHHCCCCCCH
SYMDGWWDCERLDALFTRVLQAGVDERLPKNLSDIARIAYTRLFNLQSRKRAWQVGKEHY
HHHCCCCCHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DIGNDLFRAMLDPYMQYSCGYWKEADTLEQAQLAKLKMICEKLQLKPGMSLLDIGCGWGG
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHH
LAQYAAENYGVTVHGVTISAEQQKLAQERCAGLEVEIVLQDYRDLNRQFDRIVSVGMFEH
HHHHHHHCCCEEEEEEEECHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VGPKNYDTYFRVAARNLKPDGLFLLHTIGANQTNLHVDAWINKYIFPNGCLPSVRHIAQA
CCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCEEHHHHHHHCCCCCCCCHHHHHHHHH
SEGRFVMEDWHNIGADYDRTLMAWYENFKQAWPMLSEGYSERFERMFTYYLNACAGAFRS
CCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDIQLWQVLFSPKGVEGGARVYR
CCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]