Click here to switch to the map view.

The map label for this gene is cyoB [H]

Identifier: 157369332

GI number: 157369332

Start: 1196293

End: 1198284

Strand: Reverse

Name: cyoB [H]

Synonym: Spro_1089

Alternate gene names: 157369332

Gene position: 1198284-1196293 (Counterclockwise)

Preceding gene: 157369333

Following gene: 157369331

Centisome position: 21.99

GC content: 53.26

Gene sequence:

>1992_bases
ATGTTGGGAAAATTAACGATTGATGCGGTTCCGTACCACGAACCGATCATCATGGTCACCGTTGCTGCAATTGTTATCGG
GGGTCTGGCTCTGCTGGCTCTGATAACCTATTTCGGCAAGTGGAAATGGCTATGGAGCGATTGGCTGACTTCGGTCGACC
ATAAGAAAATTGGTATCATGTACATCATCGTGGCAATGGTTATGTTGCTGCGTGGTTTTGCCGATGCCATCATGATGCGT
AGCCAGCAGGCGCTTGCGTCCGCCGGCGAGGCCGGATTCCTGCCGCCGCACCACTACGACCAGATCTTTACCGCCCACGG
CGTAATCATGATCTTCTTCATGGCGATGCCTTTCGTGGTCGGCCTGATGAACGTGGTTGTACCCTTGCAAATCGGTGCGC
GCGACGTTGCCTTCCCGTTCCTGAACTCCCTGAGCTTCTGGTTCTTCGTGGTGGGTGTCGTCCTGATCAACATCTCTCTG
GGGGTGGGTGAGTTTGCGCAGACCGGTTGGCTGGCGTATCCGCCGCTGTCGGGTAAGGAATACAGTCCTGGCGTCGGGGT
CGATTACTGGATCTGGAGTCTGCAGATTTCCGGTCTGGGTACCCTGTTGACCGGTGTGAACTTCTTCGCCACCATCATGA
AGATGCGTGCTCCTGGCATGCCTCTGATGAAGATGCCGGTGTTCACCTGGGCGGCGCTGTGTACTAACGTCCTGATCATC
GTTTCTTTCCCAATTCTGACTGTTACCATCGCGTTGCTGACCCTGGATCGCTACCTGGGCTTCCATTTCTTTACCAATGA
TATGGGCGGCAACATGATGATGTACATCAACCTGATTTGGGCCTGGGGTCACCCAGAGGTGTATATCCTGGTTCTGCCAG
TGTTTGGTGTGTTCTCTGAAGTCACCGCGACCTTCTCAAGAAAACGCCTGTTCGGCTATACCTCACTGGTATGGGCAACC
ATCGCGATTACCGTTCTGTCGTTCATCGTATGGCTGCACCACTTCTTTACCATGGGGTCCGGCGCGAACGTTAACGCCTT
CTTCGGTATCGCCACCATGATCATTTCCATCCCTACCGGGGTGAAAATCTTCAACTGGCTGTTCACCATGTACCAGGGCC
GCATTCAGCTCAACTCCGCAATGCTGTGGACCATCGGCTTCATCATCACCTTCTCCGTGGGTGGGATGACCGGCGTTCTG
CTGGCAGTACCGGGCGCGAACTTCGTGCTGCACAACAGTCTGTTCCTGATTGCCCACTTCCATAACGTGATTATCGGTGG
TGTGGTGTTTGGTTGCTTCGCCGGCCTGACCTACTGGTTCCCTAAATCCTTCGGCTTCACGCTGAACGAGACCTGGGGTA
TCCGTGCGTTCTGGTTCTGGATCATCGGTTTCTTCGTGGCCTTTATGCCACTGTATGCTCTGGGCTTTATGGGTATGACT
CGTCGTATCAGCCAGAACATCAACCCAGAGTTCCACCCACTGCTTCTGGTAGCGGCTGGCGGCGCGGCTCTGATTGCCTG
CGGTATCCTGTGCCAACTGATTCAGATTTACGTCAGTGTGCGTGACCGTGAGCAGAACCGTGATCTGACCGGTGACCCAT
GGGGCGCTCGTACGCTGGAGTGGTCTACTTCGTCTCCACCGCCGTTCTATAACTTTGCCGTAGTGCCGCAGATTCATGAC
CGTGATGAATTCTGGGACATGAAAGAAAAAGGCAACGCTTATAAGAAACCGGCGAAATACGAACCGATTCATATGCCGAA
AAATACCGGCGCCGGTGTGATTATTGCTGGCTTCAGCCTGGTATTTGGTTTCGCGATGATCTGGGACATCTGGTGGATGG
CGATCGCTGCCTTCGTAGGTATGATCGTGACCTGGATTGCCAAGAGCTTCGATGAAGATGTTGATTACTATGTGCAGGTT
GATGAAATCGAGCGCATTGAAAACCAACACTATGAACAAATCAGCAAAGCAGGCGTGAAACATGTCAACTGA

Upstream 100 bases:

>100_bases
GAACATGCACAAGGGCGCTACCACGCACGAAGGTATGGACATGAGCCAGGGTATGGACATGGGTGAACATGCAGCTCACG
CCGGAGCCGAGGAATAACTG

Downstream 100 bases:

>100_bases
TACTCTGACTAACCATGACGCAGCCCATGCAGAGCATGGGCACCACGACGCAGGTGAGACCAAAGTCTTCGGATTCTGGA
TCTACCTGATGAGCGACTGT

Product: cytochrome o ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MLGKLTIDAVPYHEPIIMVTVAAIVIGGLALLALITYFGKWKWLWSDWLTSVDHKKIGIMYIIVAMVMLLRGFADAIMMR
SQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVVGLMNVVVPLQIGARDVAFPFLNSLSFWFFVVGVVLINISL
GVGEFAQTGWLAYPPLSGKEYSPGVGVDYWIWSLQISGLGTLLTGVNFFATIMKMRAPGMPLMKMPVFTWAALCTNVLII
VSFPILTVTIALLTLDRYLGFHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSEVTATFSRKRLFGYTSLVWAT
IAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYQGRIQLNSAMLWTIGFIITFSVGGMTGVL
LAVPGANFVLHNSLFLIAHFHNVIIGGVVFGCFAGLTYWFPKSFGFTLNETWGIRAFWFWIIGFFVAFMPLYALGFMGMT
RRISQNINPEFHPLLLVAAGGAALIACGILCQLIQIYVSVRDREQNRDLTGDPWGARTLEWSTSSPPPFYNFAVVPQIHD
RDEFWDMKEKGNAYKKPAKYEPIHMPKNTGAGVIIAGFSLVFGFAMIWDIWWMAIAAFVGMIVTWIAKSFDEDVDYYVQV
DEIERIENQHYEQISKAGVKHVN

Sequences:

>Translated_663_residues
MLGKLTIDAVPYHEPIIMVTVAAIVIGGLALLALITYFGKWKWLWSDWLTSVDHKKIGIMYIIVAMVMLLRGFADAIMMR
SQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVVGLMNVVVPLQIGARDVAFPFLNSLSFWFFVVGVVLINISL
GVGEFAQTGWLAYPPLSGKEYSPGVGVDYWIWSLQISGLGTLLTGVNFFATIMKMRAPGMPLMKMPVFTWAALCTNVLII
VSFPILTVTIALLTLDRYLGFHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSEVTATFSRKRLFGYTSLVWAT
IAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYQGRIQLNSAMLWTIGFIITFSVGGMTGVL
LAVPGANFVLHNSLFLIAHFHNVIIGGVVFGCFAGLTYWFPKSFGFTLNETWGIRAFWFWIIGFFVAFMPLYALGFMGMT
RRISQNINPEFHPLLLVAAGGAALIACGILCQLIQIYVSVRDREQNRDLTGDPWGARTLEWSTSSPPPFYNFAVVPQIHD
RDEFWDMKEKGNAYKKPAKYEPIHMPKNTGAGVIIAGFSLVFGFAMIWDIWWMAIAAFVGMIVTWIAKSFDEDVDYYVQV
DEIERIENQHYEQISKAGVKHVN
>Mature_663_residues
MLGKLTIDAVPYHEPIIMVTVAAIVIGGLALLALITYFGKWKWLWSDWLTSVDHKKIGIMYIIVAMVMLLRGFADAIMMR
SQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVVGLMNVVVPLQIGARDVAFPFLNSLSFWFFVVGVVLINISL
GVGEFAQTGWLAYPPLSGKEYSPGVGVDYWIWSLQISGLGTLLTGVNFFATIMKMRAPGMPLMKMPVFTWAALCTNVLII
VSFPILTVTIALLTLDRYLGFHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSEVTATFSRKRLFGYTSLVWAT
IAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYQGRIQLNSAMLWTIGFIITFSVGGMTGVL
LAVPGANFVLHNSLFLIAHFHNVIIGGVVFGCFAGLTYWFPKSFGFTLNETWGIRAFWFWIIGFFVAFMPLYALGFMGMT
RRISQNINPEFHPLLLVAAGGAALIACGILCQLIQIYVSVRDREQNRDLTGDPWGARTLEWSTSSPPPFYNFAVVPQIHD
RDEFWDMKEKGNAYKKPAKYEPIHMPKNTGAGVIIAGFSLVFGFAMIWDIWWMAIAAFVGMIVTWIAKSFDEDVDYYVQV
DEIERIENQHYEQISKAGVKHVN

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=509, Percent_Identity=39.0962671905697, Blast_Score=330, Evalue=2e-90,
Organism=Escherichia coli, GI1786634, Length=663, Percent_Identity=83.4087481146305, Blast_Score=1172, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=441, Percent_Identity=40.3628117913832, Blast_Score=315, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=40.6153846153846, Blast_Score=231, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6226523, Length=250, Percent_Identity=33.2, Blast_Score=124, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74345; Mature: 74345

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGKLTIDAVPYHEPIIMVTVAAIVIGGLALLALITYFGKWKWLWSDWLTSVDHKKIGIM
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHH
YIIVAMVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNVVVPLQIGARDVAFPFLNSLSFWFFVVGVVLINISLGVGEFAQTGWLAYPPLSGKE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEECCCCCCCC
YSPGVGVDYWIWSLQISGLGTLLTGVNFFATIMKMRAPGMPLMKMPVFTWAALCTNVLII
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VSFPILTVTIALLTLDRYLGFHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSE
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEEECCCCCEEEEEEEHHHHHHH
VTATFSRKRLFGYTSLVWATIAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VKIFNWLFTMYQGRIQLNSAMLWTIGFIITFSVGGMTGVLLAVPGANFVLHNSLFLIAHF
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEHHCHHHHHHHH
HNVIIGGVVFGCFAGLTYWFPKSFGFTLNETWGIRAFWFWIIGFFVAFMPLYALGFMGMT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRISQNINPEFHPLLLVAAGGAALIACGILCQLIQIYVSVRDREQNRDLTGDPWGARTLE
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
WSTSSPPPFYNFAVVPQIHDRDEFWDMKEKGNAYKKPAKYEPIHMPKNTGAGVIIAGFSL
CCCCCCCCCCEEEECCCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHH
VFGFAMIWDIWWMAIAAFVGMIVTWIAKSFDEDVDYYVQVDEIERIENQHYEQISKAGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCC
HVN
CCC
>Mature Secondary Structure
MLGKLTIDAVPYHEPIIMVTVAAIVIGGLALLALITYFGKWKWLWSDWLTSVDHKKIGIM
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHH
YIIVAMVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFMAMPFVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNVVVPLQIGARDVAFPFLNSLSFWFFVVGVVLINISLGVGEFAQTGWLAYPPLSGKE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEECCCCCCCC
YSPGVGVDYWIWSLQISGLGTLLTGVNFFATIMKMRAPGMPLMKMPVFTWAALCTNVLII
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VSFPILTVTIALLTLDRYLGFHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGVFSE
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEEECCCCCEEEEEEEHHHHHHH
VTATFSRKRLFGYTSLVWATIAITVLSFIVWLHHFFTMGSGANVNAFFGIATMIISIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VKIFNWLFTMYQGRIQLNSAMLWTIGFIITFSVGGMTGVLLAVPGANFVLHNSLFLIAHF
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEHHCHHHHHHHH
HNVIIGGVVFGCFAGLTYWFPKSFGFTLNETWGIRAFWFWIIGFFVAFMPLYALGFMGMT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRISQNINPEFHPLLLVAAGGAALIACGILCQLIQIYVSVRDREQNRDLTGDPWGARTLE
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
WSTSSPPPFYNFAVVPQIHDRDEFWDMKEKGNAYKKPAKYEPIHMPKNTGAGVIIAGFSL
CCCCCCCCCCEEEECCCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHH
VFGFAMIWDIWWMAIAAFVGMIVTWIAKSFDEDVDYYVQVDEIERIENQHYEQISKAGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCC
HVN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]