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The map label for this gene is fbaA [H]

Identifier: 157369276

GI number: 157369276

Start: 1135465

End: 1136325

Strand: Direct

Name: fbaA [H]

Synonym: Spro_1033

Alternate gene names: 157369276

Gene position: 1135465-1136325 (Clockwise)

Preceding gene: 157369275

Following gene: 157369277

Centisome position: 20.84

GC content: 59.7

Gene sequence:

>861_bases
ATGGCATTGATTTCATTGGCGCAGGGTTTGGCGCAGGCTCGTCAACACGGCTATGCGCTGGGCGCATTCAACGTGCTCGA
CAGCCATTTCCTGCGTGCGTTGTTTGCTGCGGCGCAGGCGGCGCGATCGCCGTTTATTATCAATATTGCCGAAGTGCACT
TTAAGTACGTCTCGCTGGAGTCGCTGGTGGCGGCGATTAAAAGTGAAGTGGCGCAGCATGATATCCCGGTGGTGTTGAAT
CTGGATCACGGTCTGCATTTCGAGGCGGTGGTGCAGGCGCTGCGGCTGGGATTCAGCTCGGTGATGTTCGACGGTTCCGG
CCTGAGCTACGAAGAGAACGTGCGTCAGACGCAGGAAGTGGTGCGCATGTGTCACGCGGTCGGCGTCTCGGTTGAGGCTG
AGCTGGGGGCGGTCGGCGGTGACGAAGGCGGCGCGCTGTACGGCGAGGCCGACAGCAACAAATTTACCGACCCGCAGCGG
GCGCGCGAATTTGTCGAATTGACCGGCATTGATGCGCTGGCGGTGGCGATTGGCAATGCGCACGGCAAATATAAAGGCGA
GCCGAAGCTCGATTTTGAGCGGTTGGCGGCTATCCAGCAGCAGGCGGGGATCCCACTGGTGCTGCACGGCGGTTCCGGCA
TCAGCGACGCCGATTTCAAACGCGCCATTGGCCTGGGAATTCACAAAATCAATTTCTATACCGGCATGTCTCAGGCGGCG
CTGGGGGCGGTGGAGCAGCGGATAACGCAACGCCACGCGATTTACGATGAATTCGCCGAAGTGTTGCTGGCGGTGGAGCA
GTCGATCAGCGAAGTGGTGCAGCAGCAAATGCATATTTTCGGCAGCGCCGGGCGGTTGTGA

Upstream 100 bases:

>100_bases
TGCAGCCGCTCAGCCGCTTTAGCCAGATTGAAGAGGACCAGCCACCGCAGTGGTTGCTGTGTCATGAATACTTGCGCTTT
ATCGCTTAAGGAGAACCAGC

Downstream 100 bases:

>100_bases
TGAGCCGGCGTGGCATTGTTTCGGCCGGCAATATGCTGGTGGATCATGTGCATCAAATTGCACACTGGCCGCAGCCGGGC
TGGCTGGTTGAGATTGAACA

Product: hypothetical protein

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MALISLAQGLAQARQHGYALGAFNVLDSHFLRALFAAAQAARSPFIINIAEVHFKYVSLESLVAAIKSEVAQHDIPVVLN
LDHGLHFEAVVQALRLGFSSVMFDGSGLSYEENVRQTQEVVRMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPQR
AREFVELTGIDALAVAIGNAHGKYKGEPKLDFERLAAIQQQAGIPLVLHGGSGISDADFKRAIGLGIHKINFYTGMSQAA
LGAVEQRITQRHAIYDEFAEVLLAVEQSISEVVQQQMHIFGSAGRL

Sequences:

>Translated_286_residues
MALISLAQGLAQARQHGYALGAFNVLDSHFLRALFAAAQAARSPFIINIAEVHFKYVSLESLVAAIKSEVAQHDIPVVLN
LDHGLHFEAVVQALRLGFSSVMFDGSGLSYEENVRQTQEVVRMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPQR
AREFVELTGIDALAVAIGNAHGKYKGEPKLDFERLAAIQQQAGIPLVLHGGSGISDADFKRAIGLGIHKINFYTGMSQAA
LGAVEQRITQRHAIYDEFAEVLLAVEQSISEVVQQQMHIFGSAGRL
>Mature_285_residues
ALISLAQGLAQARQHGYALGAFNVLDSHFLRALFAAAQAARSPFIINIAEVHFKYVSLESLVAAIKSEVAQHDIPVVLNL
DHGLHFEAVVQALRLGFSSVMFDGSGLSYEENVRQTQEVVRMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPQRA
REFVELTGIDALAVAIGNAHGKYKGEPKLDFERLAAIQQQAGIPLVLHGGSGISDADFKRAIGLGIHKINFYTGMSQAAL
GAVEQRITQRHAIYDEFAEVLLAVEQSISEVVQQQMHIFGSAGRL

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=286, Percent_Identity=37.7622377622378, Blast_Score=197, Evalue=5e-52,
Organism=Escherichia coli, GI87082041, Length=285, Percent_Identity=38.9473684210526, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1788072, Length=275, Percent_Identity=40.3636363636364, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789293, Length=283, Percent_Identity=24.7349823321555, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322790, Length=282, Percent_Identity=28.7234042553192, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30708; Mature: 30577

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLAQGLAQARQHGYALGAFNVLDSHFLRALFAAAQAARSPFIINIAEVHFKYVSLE
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHH
SLVAAIKSEVAQHDIPVVLNLDHGLHFEAVVQALRLGFSSVMFDGSGLSYEENVRQTQEV
HHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCHHHHEECCCCCCHHHHHHHHHHH
VRMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPQRAREFVELTGIDALAVAIGNA
HHHHHHHCCCEEHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCC
HGKYKGEPKLDFERLAAIQQQAGIPLVLHGGSGISDADFKRAIGLGIHKINFYTGMSQAA
CCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCEEEEHHHCHHHHH
LGAVEQRITQRHAIYDEFAEVLLAVEQSISEVVQQQMHIFGSAGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALISLAQGLAQARQHGYALGAFNVLDSHFLRALFAAAQAARSPFIINIAEVHFKYVSLE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHH
SLVAAIKSEVAQHDIPVVLNLDHGLHFEAVVQALRLGFSSVMFDGSGLSYEENVRQTQEV
HHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCHHHHEECCCCCCHHHHHHHHHHH
VRMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPQRAREFVELTGIDALAVAIGNA
HHHHHHHCCCEEHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCC
HGKYKGEPKLDFERLAAIQQQAGIPLVLHGGSGISDADFKRAIGLGIHKINFYTGMSQAA
CCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCEEEEHHHCHHHHH
LGAVEQRITQRHAIYDEFAEVLLAVEQSISEVVQQQMHIFGSAGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2457578; 1640835; 9353933; 9384377; 1556067 [H]