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The map label for this gene is hutU [H]

Identifier: 157369050

GI number: 157369050

Start: 899932

End: 901713

Strand: Reverse

Name: hutU [H]

Synonym: Spro_0805

Alternate gene names: 157369050

Gene position: 901713-899932 (Counterclockwise)

Preceding gene: 157369051

Following gene: 157369049

Centisome position: 16.55

GC content: 59.15

Gene sequence:

>1782_bases
ATGTTAATAAACCCTACGCATTGTTATGGCGTGGTGATTCACCCCACCGCGTTATGGGATTCTGCACCAATACTGTTTGA
GGAAAATGCTGTGACTGCAAATAACAAAGTTCGCAATGTCGAAGTACGCGCGCCACGCGGCACAAAATTAAATGCAAAAA
GCTGGCTGACCGAAGCGCCGTTGCGCATGCTGATGAACAACCTCGATCCTGAAGTGGCGGAGAACCCGCACGAGCTGGTG
GTATACGGCGGTATTGGCCGCGCCGCGCGTGACTGGGATTGCTACGACAAAATTGTCGCTACCCTGAAAACCCTGGAAGA
CGACGAAACCCTGCTGGTGCAGTCCGGCAAACCGGTTGGGGTATTCAAAACCCACAGCAACGCGCCACGCGTGCTGATCG
CCAACTCCAACCTGGTGCCTCACTGGGCAACCTGGGAACACTTTAACGAACTGGATGCCAAAGGCCTGGCCATGTACGGC
CAGATGACCGCCGGCAGCTGGATCTACATCGGCAGCCAGGGCATCGTCCAGGGCACCTACGAGACCTTCGTCGAAGCGGG
TCGCCAGCATTATGACGGCAGCCTGCAAGGCCGCTGGGTACTGACCGCCGGTCTGGGTGGCATGGGTGGCGCACAGCCGC
TGGCCGCCACGCTGGCAGGTGCTTGCTCGCTGAACATCGAATGCCAGCAGAGCCGCATCGATTTCCGCCTGAAAACCCGC
TATGTCGATGAACAGGCCAAAGATCTGGACGACGCACTGGCCCGCATCAAGAAATACACCGCTGAAGGCAAAGCCATCTC
CATCGCCCTGTGCGGTAACGCGGCGGACGTTTTGCCGGAACTGGTGCGCCGCGGCGTGCGTCCAGACATGGTCACCGACC
AGACCAGCGCCCACGATCCGCTGAACGGCTACCTGCCTAAGGGCTGGAGCTGGGAAGAATACCGTCAGCGTGCGCTGACC
GAACCCGCTCAGGTGGTTATCGCCGCCAAGCAGTCAATGGCTGAACACGTTGAAGCCATGCTGGCGTTCCAGAAAATGGG
CGTGCCAACCTTCGACTACGGCAACAACATTCGTCAGATGGCGAAAGAAATGGGCGTCAGCAATGCCTTTGATTTCCCAG
GCTTCGTACCGGCTTATATCCGTCCGCTGTTCTGCCGCGGCGTTGGCCCGTTCCGCTGGGCCGCACTGTCTGGCGATCCA
CAAGACATCTACAAAACCGACGCCATGGTTAAAGAATTGATCCCGGATGACGAGCATCTGCACCGCTGGCTGGATATGGC
ACGCGAGCGCATCAGCTTCCAGGGTCTGCCGGCACGTATCTGCTGGGTCGGTCTGGGCCAACGCGCCAAACTGGGTCTGG
CGTTCAACGAAATGGTCCGCAGCGGTGAGCTGTCTGCACCTATCGTCATCGGCCGTGACCATCTGGACTCCGGCTCGGTT
GCCAGCCCGAACCGTGAAACCGAATCAATGAAAGACGGCTCAGACGCCGTATCCGACTGGCCGTTGCTCAATGCCCTGCT
CAATACCGCCAGCGGCGCGACCTGGGTTTCCCTGCACCACGGCGGTGGCGTCGGCATGGGCTTCTCCCAACACTCCGGTA
TGGTTATCGTTTGTGACGGCACCGATGAAGCCGCAGAACGCATCGCCCGCGTATTACATAATGACCCGGCCACCGGCGTA
ATGCGTCACGCCGATGCCGGTTACGACATCGCCATTGAATGCGCCCGCGAGCAAGGTCTGAACCTGCCGATGGTGGCTGC
GACTCAAGGAGACAAAGCATGA

Upstream 100 bases:

>100_bases
ATTAAATAACATCATATTGATTAATAACAAAAATAACTTTCTCTTATGCCATTTTGGGCATCCACTGGTCGGTGTTGCAT
ATGCTTGTACATACAAGTAT

Downstream 100 bases:

>100_bases
AAGCGCTGACTATTCGCCCAGGCCAACTGACACTGGCGCAACTGCGTGAAATTTATCAACACCCGGTCACCCTGACTCTG
GACGACAACGCCTACGCAGA

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MLINPTHCYGVVIHPTALWDSAPILFEENAVTANNKVRNVEVRAPRGTKLNAKSWLTEAPLRMLMNNLDPEVAENPHELV
VYGGIGRAARDWDCYDKIVATLKTLEDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYG
QMTAGSWIYIGSQGIVQGTYETFVEAGRQHYDGSLQGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLKTR
YVDEQAKDLDDALARIKKYTAEGKAISIALCGNAADVLPELVRRGVRPDMVTDQTSAHDPLNGYLPKGWSWEEYRQRALT
EPAQVVIAAKQSMAEHVEAMLAFQKMGVPTFDYGNNIRQMAKEMGVSNAFDFPGFVPAYIRPLFCRGVGPFRWAALSGDP
QDIYKTDAMVKELIPDDEHLHRWLDMARERISFQGLPARICWVGLGQRAKLGLAFNEMVRSGELSAPIVIGRDHLDSGSV
ASPNRETESMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAERIARVLHNDPATGV
MRHADAGYDIAIECAREQGLNLPMVAATQGDKA

Sequences:

>Translated_593_residues
MLINPTHCYGVVIHPTALWDSAPILFEENAVTANNKVRNVEVRAPRGTKLNAKSWLTEAPLRMLMNNLDPEVAENPHELV
VYGGIGRAARDWDCYDKIVATLKTLEDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYG
QMTAGSWIYIGSQGIVQGTYETFVEAGRQHYDGSLQGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLKTR
YVDEQAKDLDDALARIKKYTAEGKAISIALCGNAADVLPELVRRGVRPDMVTDQTSAHDPLNGYLPKGWSWEEYRQRALT
EPAQVVIAAKQSMAEHVEAMLAFQKMGVPTFDYGNNIRQMAKEMGVSNAFDFPGFVPAYIRPLFCRGVGPFRWAALSGDP
QDIYKTDAMVKELIPDDEHLHRWLDMARERISFQGLPARICWVGLGQRAKLGLAFNEMVRSGELSAPIVIGRDHLDSGSV
ASPNRETESMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAERIARVLHNDPATGV
MRHADAGYDIAIECAREQGLNLPMVAATQGDKA
>Mature_593_residues
MLINPTHCYGVVIHPTALWDSAPILFEENAVTANNKVRNVEVRAPRGTKLNAKSWLTEAPLRMLMNNLDPEVAENPHELV
VYGGIGRAARDWDCYDKIVATLKTLEDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYG
QMTAGSWIYIGSQGIVQGTYETFVEAGRQHYDGSLQGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLKTR
YVDEQAKDLDDALARIKKYTAEGKAISIALCGNAADVLPELVRRGVRPDMVTDQTSAHDPLNGYLPKGWSWEEYRQRALT
EPAQVVIAAKQSMAEHVEAMLAFQKMGVPTFDYGNNIRQMAKEMGVSNAFDFPGFVPAYIRPLFCRGVGPFRWAALSGDP
QDIYKTDAMVKELIPDDEHLHRWLDMARERISFQGLPARICWVGLGQRAKLGLAFNEMVRSGELSAPIVIGRDHLDSGSV
ASPNRETESMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAERIARVLHNDPATGV
MRHADAGYDIAIECAREQGLNLPMVAATQGDKA

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=572, Percent_Identity=33.041958041958, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI260306182, Length=220, Percent_Identity=36.3636363636364, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71997891, Length=581, Percent_Identity=34.4234079173838, Blast_Score=330, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 64832; Mature: 64832

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINPTHCYGVVIHPTALWDSAPILFEENAVTANNKVRNVEVRAPRGTKLNAKSWLTEAP
CCCCCCEEEEEEEECHHHCCCCCEEEECCEEECCCCEEEEEEECCCCCCCCHHHHHHHHH
LRMLMNNLDPEVAENPHELVVYGGIGRAARDWDCYDKIVATLKTLEDDETLLVQSGKPVG
HHHHHHHCCHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEE
VFKTHSNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTY
EEEECCCCCEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCHHH
ETFVEAGRQHYDGSLQGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLKTR
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEEEEEECCCCCEEEEEH
YVDEQAKDLDDALARIKKYTAEGKAISIALCGNAADVLPELVRRGVRPDMVTDQTSAHDP
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
LNGYLPKGWSWEEYRQRALTEPAQVVIAAKQSMAEHVEAMLAFQKMGVPTFDYGNNIRQM
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AKEMGVSNAFDFPGFVPAYIRPLFCRGVGPFRWAALSGDPQDIYKTDAMVKELIPDDEHL
HHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHH
HRWLDMARERISFQGLPARICWVGLGQRAKLGLAFNEMVRSGELSAPIVIGRDHLDSGSV
HHHHHHHHHHHCCCCCCEEEEEEECCCCCEECHHHHHHHHCCCCCCCEEEECCCCCCCCC
ASPNRETESMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDG
CCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECC
TDEAAERIARVLHNDPATGVMRHADAGYDIAIECAREQGLNLPMVAATQGDKA
CHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEHHHCCCCCCEEEECCCCCC
>Mature Secondary Structure
MLINPTHCYGVVIHPTALWDSAPILFEENAVTANNKVRNVEVRAPRGTKLNAKSWLTEAP
CCCCCCEEEEEEEECHHHCCCCCEEEECCEEECCCCEEEEEEECCCCCCCCHHHHHHHHH
LRMLMNNLDPEVAENPHELVVYGGIGRAARDWDCYDKIVATLKTLEDDETLLVQSGKPVG
HHHHHHHCCHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEE
VFKTHSNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTY
EEEECCCCCEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCHHH
ETFVEAGRQHYDGSLQGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLKTR
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEEEEEECCCCCEEEEEH
YVDEQAKDLDDALARIKKYTAEGKAISIALCGNAADVLPELVRRGVRPDMVTDQTSAHDP
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
LNGYLPKGWSWEEYRQRALTEPAQVVIAAKQSMAEHVEAMLAFQKMGVPTFDYGNNIRQM
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AKEMGVSNAFDFPGFVPAYIRPLFCRGVGPFRWAALSGDPQDIYKTDAMVKELIPDDEHL
HHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHH
HRWLDMARERISFQGLPARICWVGLGQRAKLGLAFNEMVRSGELSAPIVIGRDHLDSGSV
HHHHHHHHHHHCCCCCCEEEEEEECCCCCEECHHHHHHHHCCCCCCCEEEECCCCCCCCC
ASPNRETESMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDG
CCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECC
TDEAAERIARVLHNDPATGVMRHADAGYDIAIECAREQGLNLPMVAATQGDKA
CHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEHHHCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA