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The map label for this gene is mtnN

Identifier: 157369032

GI number: 157369032

Start: 875664

End: 876365

Strand: Reverse

Name: mtnN

Synonym: Spro_0787

Alternate gene names: 157369032

Gene position: 876365-875664 (Counterclockwise)

Preceding gene: 157369035

Following gene: 157369031

Centisome position: 16.08

GC content: 58.83

Gene sequence:

>702_bases
ATGAAAGTAGGCATCATCGGCGCAATGGAGCAGGAAGTCACCCTGCTGCGCGATCAAATTGAAAACCGTCAGACCATTCA
ACGCGCGGGCTGTGAAATCTATACCGGCCAGATCGGCGGTGTTGACGTGGCGCTGCTCAAATCCGGCATCGGTAAGGTTT
CTGCCGCCATGGGTACCACCCTGCTGCTGGAACACTGCAAGCCGGACCTGGTGATCAATACCGGTTCCGCCGGTGGCCTG
GCCAGCACGCTGAAGGTCGGCGATATTGTGGTATCCGAAGAAGTGCGCTACCACGATGCCGACGTGACCGCCTTTGGATA
CGAGCCAGGCCAGATGGCCGGCTGCCCGGCGGCGTTTGTGGCAGACGACGCGCTGATTGCGCTGGCCGAAAGCTGCATCA
AACAATTGAACCTGAACGCTGTACGCGGCCTGATTTGCAGCGGTGATGCTTTCATTAACGGTGCAGAGCCACTGGCACGC
ATCCGCGCTACCTTCCCGAACGTAGCGGCAGTAGAAATGGAAGCCGCGGCAGTCGGGCACGTCTGCCATCTGTTCGGCAC
GCCGTTTGTGGTAGTGCGCGCTATCTCTGACGTGGCCGACAGTGAATCGCACATGAGTTTTGAGGAGTTCCTTGTCGTGG
CGGCCAAGCAATCTACGCTGATGGTCAACGCCATGCTGCAGACTCTGGCTAAGCGCGGTTGA

Upstream 100 bases:

>100_bases
GTGATAACAATTCCCGACGGCATATGCAACGGATTATCTCTCTATGAGAGCCATGATAGACTATGGCGAAATTCCCACAC
CCAATCAGTGAGCGTTATTT

Downstream 100 bases:

>100_bases
TGTGACGCGACGCTTTTCAGCCCTGCTGTGGCTGCTGGCATTATGGATGGCGCTGCCCGTCGGCGCCGCCCAACGGGTGA
TCAGCCTGGCACCCAACACC

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKVGIIGAMEQEVTLLRDQIENRQTIQRAGCEIYTGQIGGVDVALLKSGIGKVSAAMGTTLLLEHCKPDLVINTGSAGGL
ASTLKVGDIVVSEEVRYHDADVTAFGYEPGQMAGCPAAFVADDALIALAESCIKQLNLNAVRGLICSGDAFINGAEPLAR
IRATFPNVAAVEMEAAAVGHVCHLFGTPFVVVRAISDVADSESHMSFEEFLVVAAKQSTLMVNAMLQTLAKRG

Sequences:

>Translated_233_residues
MKVGIIGAMEQEVTLLRDQIENRQTIQRAGCEIYTGQIGGVDVALLKSGIGKVSAAMGTTLLLEHCKPDLVINTGSAGGL
ASTLKVGDIVVSEEVRYHDADVTAFGYEPGQMAGCPAAFVADDALIALAESCIKQLNLNAVRGLICSGDAFINGAEPLAR
IRATFPNVAAVEMEAAAVGHVCHLFGTPFVVVRAISDVADSESHMSFEEFLVVAAKQSTLMVNAMLQTLAKRG
>Mature_233_residues
MKVGIIGAMEQEVTLLRDQIENRQTIQRAGCEIYTGQIGGVDVALLKSGIGKVSAAMGTTLLLEHCKPDLVINTGSAGGL
ASTLKVGDIVVSEEVRYHDADVTAFGYEPGQMAGCPAAFVADDALIALAESCIKQLNLNAVRGLICSGDAFINGAEPLAR
IRATFPNVAAVEMEAAAVGHVCHLFGTPFVVVRAISDVADSESHMSFEEFLVVAAKQSTLMVNAMLQTLAKRG

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=76.0869565217391, Blast_Score=328, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNN_SERP5 (A8G9V3)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477021.1
- ProteinModelPortal:   A8G9V3
- SMR:   A8G9V3
- STRING:   A8G9V3
- GeneID:   5604129
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0787
- eggNOG:   COG0775
- HOGENOM:   HBG367723
- OMA:   AMEQEVT
- ProtClustDB:   PRK05584
- BioCyc:   SPRO399741:SPRO_0787-MONOMER
- HAMAP:   MF_01684
- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR01704

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =3.2.2.9

Molecular weight: Translated: 24449; Mature: 24449

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: ACT_SITE 12-12 BINDING 78-78 BINDING 152-152 BINDING 197-197

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGIIGAMEQEVTLLRDQIENRQTIQRAGCEIYTGQIGGVDVALLKSGIGKVSAAMGTT
CCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCHHHHHHHHHH
LLLEHCKPDLVINTGSAGGLASTLKVGDIVVSEEVRYHDADVTAFGYEPGQMAGCPAAFV
HHHHHCCCCEEEECCCCCCHHHHHHHCCEEEECCCEECCCCEEEECCCCCCCCCCCHHHH
ADDALIALAESCIKQLNLNAVRGLICSGDAFINGAEPLARIRATFPNVAAVEMEAAAVGH
HHHHHHHHHHHHHHHHCHHHHHHEEECCCCEECCCHHHHHHHHCCCCEEEEEHHHHHHHH
VCHLFGTPFVVVRAISDVADSESHMSFEEFLVVAAKQSTLMVNAMLQTLAKRG
HHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVGIIGAMEQEVTLLRDQIENRQTIQRAGCEIYTGQIGGVDVALLKSGIGKVSAAMGTT
CCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCHHHHHHHHHH
LLLEHCKPDLVINTGSAGGLASTLKVGDIVVSEEVRYHDADVTAFGYEPGQMAGCPAAFV
HHHHHCCCCEEEECCCCCCHHHHHHHCCEEEECCCEECCCCEEEECCCCCCCCCCCHHHH
ADDALIALAESCIKQLNLNAVRGLICSGDAFINGAEPLARIRATFPNVAAVEMEAAAVGH
HHHHHHHHHHHHHHHHCHHHHHHEEECCCCEECCCHHHHHHHHCCCCEEEEEHHHHHHHH
VCHLFGTPFVVVRAISDVADSESHMSFEEFLVVAAKQSTLMVNAMLQTLAKRG
HHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA