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The map label for this gene is hofC [H]

Identifier: 157369021

GI number: 157369021

Start: 865060

End: 866259

Strand: Reverse

Name: hofC [H]

Synonym: Spro_0776

Alternate gene names: 157369021

Gene position: 866259-865060 (Counterclockwise)

Preceding gene: 157369022

Following gene: 157369019

Centisome position: 15.9

GC content: 57.67

Gene sequence:

>1200_bases
GTGAAAGCGCTGCGCCTTTTCCTCTGGCAGGCGATTGACCCTCTGGGTCAACTGCGTCAGGGCGAACTGATGTGCAGCGA
AAAGAATTTGGTCAGCCACTGGCTGATCGAACAAGGGCTGCAGCCCTGCCAGATTAACAGCGGAAAACGTATTGCCCCCA
GTCAGTGGCGCGGCGAACCCTTGATCCAGTTCACCCGCCAACTTGCCACCCTGCTGCAGGCCGGGTTGCCGCTGGTCAGC
GGGTTGCAGTTGCTGGCGGCAGAACACCCGTCTGCCGCCTGGCGCTGTCTGCTGCGGGACATCAGCGAACAGGTGCGGCA
AGGCCAACCCTTTTCCGAGGTTATCGCCGGGCAACATGCCATCTTTCCTCTGATCTACCGCCAGTTGATCGCCATTGGGG
AACTGACCGGCCACCTGGAACAGTGCTGCTTGCAACTGGCCCAACAGCAGGAAGCACAGCAAAAATTGCAGAAGAAAGTG
GTTAAGGCGCTGCGTTATCCCTTGTTTATCTGCGCAGTAGCGCTGTTGGTGAGCATTCTGATGTTGGTCATGGTGTTACC
GGAATTTGCCGGCGTCTATCAGTCCTTCAATGCGCCGCTGCCGTGGTTTACCCAGGGGCTGCTGAACCTTTCTACCTGGT
TGATCCACGGCGGCCCCTGGCTGGTGACGGGGATGGGTTGCACAATATTTGCTTATTTTCGAAGACTGCACCCGCAGTCA
CACTGGCGCAGGCGCGAACAGGCGGCATTACTGCGCCTGCCGCTGATCGCTCAATTGATCAAGGGCGGTTGCCTGAGCCA
AATATTCCGCATTCTGGCCATGACTCAGCAGGCCGGGCTCACGTTGGTTGAAGGATTGAATGCCGCAGCGCTGTCGGTGG
ACAACCTGTTTTACCGACAGGCGATGGAGAAGGTGCAGCACCAGATAGCGCAGGGTCAGACTTTCCACAGTGCGTTGGGG
GAACAGGCACTTTTCCCCCCACTTTGTCAGCAGTTAGTCCGGGTGGGCGAAGAATCCGGCTCGTTAGATACGCTGTTGGG
CAAGCTGGCGCTGTGGCATGAGCAGCAAACTTTTGAGTTGGCCGATACGCTGGCGCAAACGCTGGAACCACTCTTGATGC
TGGTGGTGGGCGGGATCGTCGGCACGCTGGTGATCGCCATGTATTTGCCGATATTCCAGTTGGGGAATGTTTTGGGGTAA

Upstream 100 bases:

>100_bases
CAACGCTGCTGCAAGCCGGATTAACGCTGGTTTCACAAGGCGTCACATCGCTGGAAGAGGTATACCGTATTGTCGGCATC
ATTGCCGGTGAGGAGGCACC

Downstream 100 bases:

>100_bases
GTTCTGGAAAACCTTGAGTGCAGCACTGAACTGCGCCCAAGGTTTGGTCAGGTTGAAGCGAGCCGGATTAGTTACTGCCG
AATACGCGGTTTTCCTGCTC

Product: type IV pilin biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKALRLFLWQAIDPLGQLRQGELMCSEKNLVSHWLIEQGLQPCQINSGKRIAPSQWRGEPLIQFTRQLATLLQAGLPLVS
GLQLLAAEHPSAAWRCLLRDISEQVRQGQPFSEVIAGQHAIFPLIYRQLIAIGELTGHLEQCCLQLAQQQEAQQKLQKKV
VKALRYPLFICAVALLVSILMLVMVLPEFAGVYQSFNAPLPWFTQGLLNLSTWLIHGGPWLVTGMGCTIFAYFRRLHPQS
HWRRREQAALLRLPLIAQLIKGGCLSQIFRILAMTQQAGLTLVEGLNAAALSVDNLFYRQAMEKVQHQIAQGQTFHSALG
EQALFPPLCQQLVRVGEESGSLDTLLGKLALWHEQQTFELADTLAQTLEPLLMLVVGGIVGTLVIAMYLPIFQLGNVLG

Sequences:

>Translated_399_residues
MKALRLFLWQAIDPLGQLRQGELMCSEKNLVSHWLIEQGLQPCQINSGKRIAPSQWRGEPLIQFTRQLATLLQAGLPLVS
GLQLLAAEHPSAAWRCLLRDISEQVRQGQPFSEVIAGQHAIFPLIYRQLIAIGELTGHLEQCCLQLAQQQEAQQKLQKKV
VKALRYPLFICAVALLVSILMLVMVLPEFAGVYQSFNAPLPWFTQGLLNLSTWLIHGGPWLVTGMGCTIFAYFRRLHPQS
HWRRREQAALLRLPLIAQLIKGGCLSQIFRILAMTQQAGLTLVEGLNAAALSVDNLFYRQAMEKVQHQIAQGQTFHSALG
EQALFPPLCQQLVRVGEESGSLDTLLGKLALWHEQQTFELADTLAQTLEPLLMLVVGGIVGTLVIAMYLPIFQLGNVLG
>Mature_399_residues
MKALRLFLWQAIDPLGQLRQGELMCSEKNLVSHWLIEQGLQPCQINSGKRIAPSQWRGEPLIQFTRQLATLLQAGLPLVS
GLQLLAAEHPSAAWRCLLRDISEQVRQGQPFSEVIAGQHAIFPLIYRQLIAIGELTGHLEQCCLQLAQQQEAQQKLQKKV
VKALRYPLFICAVALLVSILMLVMVLPEFAGVYQSFNAPLPWFTQGLLNLSTWLIHGGPWLVTGMGCTIFAYFRRLHPQS
HWRRREQAALLRLPLIAQLIKGGCLSQIFRILAMTQQAGLTLVEGLNAAALSVDNLFYRQAMEKVQHQIAQGQTFHSALG
EQALFPPLCQQLVRVGEESGSLDTLLGKLALWHEQQTFELADTLAQTLEPLLMLVVGGIVGTLVIAMYLPIFQLGNVLG

Specific function: Unknown

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1786295, Length=403, Percent_Identity=42.4317617866005, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1789724, Length=399, Percent_Identity=30.0751879699248, Blast_Score=162, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44453; Mature: 44453

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALRLFLWQAIDPLGQLRQGELMCSEKNLVSHWLIEQGLQPCQINSGKRIAPSQWRGEP
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
LIQFTRQLATLLQAGLPLVSGLQLLAAEHPSAAWRCLLRDISEQVRQGQPFSEVIAGQHA
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHH
IFPLIYRQLIAIGELTGHLEQCCLQLAQQQEAQQKLQKKVVKALRYPLFICAVALLVSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVMVLPEFAGVYQSFNAPLPWFTQGLLNLSTWLIHGGPWLVTGMGCTIFAYFRRLHPQS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCHH
HWRRREQAALLRLPLIAQLIKGGCLSQIFRILAMTQQAGLTLVEGLNAAALSVDNLFYRQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHH
AMEKVQHQIAQGQTFHSALGEQALFPPLCQQLVRVGEESGSLDTLLGKLALWHEQQTFEL
HHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ADTLAQTLEPLLMLVVGGIVGTLVIAMYLPIFQLGNVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7959070; 8202364; 9278503; 2904262 [H]