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The map label for this gene is coaE [H]

Identifier: 157369019

GI number: 157369019

Start: 863003

End: 863617

Strand: Reverse

Name: coaE [H]

Synonym: Spro_0774

Alternate gene names: 157369019

Gene position: 863617-863003 (Counterclockwise)

Preceding gene: 157369021

Following gene: 157369018

Centisome position: 15.85

GC content: 58.54

Gene sequence:

>615_bases
ATGGCCTACATTGTTGCGTTGACAGGGGGTATCGGCAGCGGTAAGTCAACCGTGGCAGATGCCTTTGCCCGCCATGGCGT
GACGGTGGTCGATGCAGACGTTATCGCCAGGCAAGTTGTCGAACCTGGCACCCCGGCGCTGGCTGCTATCGCCAAACGTT
TTGGTAATGAAATGTTGCAGCCTGATGGCAGGCTTAACCGCGCTGCGCTCCGTCAGCGCATCTTCAGTAACCCGGATGAA
AAGAGCTGGCTGAACCAACTGCTGCACCCGCTGATTCATCAGAAAACCCAATGCCAACTGGCGCAAGTGACCAGTCCTTA
TGCACTTTGGGTGGTTCCCCTGCTGGTTGAAAACAACCTGCAGGCACGCGCCGATCGCGTCCTGGTGGTCGACGTTGACA
GCGAGACTCAGTTGGCCAGAACCATCGCCCGCGACGGCATCAGCCGTCAGCAGGCACAGAACATACTGTCCGCGCAGGTC
ACGCGCGAGCAGCGCCTGGCCGCTGCAGATGACATAATTGATAATAGCGGCACCGCTCAGGGGATAGAGCCATTGGTTGC
CGCACTGCATCGCCGTTACCTTGAGCTGGCGGCATCAGCGACCCGACAGGATTAA

Upstream 100 bases:

>100_bases
CAAGCTGCCGAACAAGCGCCGCCTGCTGACTTGCACTTCTGCGCGATCGCTTTATGATTCGTCTATTATTTTTTTATGAA
CATCAGGTGCATTCCCTACC

Downstream 100 bases:

>100_bases
ACTGAATGAGTGATGTTTCCCCAAGCGTTCTTTTTGAACACCCGTTGAATGAAAAAATGCGTACCTGGTTGCGTATGGAA
TTTTTACTGCAGCAATTGCA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MAYIVALTGGIGSGKSTVADAFARHGVTVVDADVIARQVVEPGTPALAAIAKRFGNEMLQPDGRLNRAALRQRIFSNPDE
KSWLNQLLHPLIHQKTQCQLAQVTSPYALWVVPLLVENNLQARADRVLVVDVDSETQLARTIARDGISRQQAQNILSAQV
TREQRLAAADDIIDNSGTAQGIEPLVAALHRRYLELAASATRQD

Sequences:

>Translated_204_residues
MAYIVALTGGIGSGKSTVADAFARHGVTVVDADVIARQVVEPGTPALAAIAKRFGNEMLQPDGRLNRAALRQRIFSNPDE
KSWLNQLLHPLIHQKTQCQLAQVTSPYALWVVPLLVENNLQARADRVLVVDVDSETQLARTIARDGISRQQAQNILSAQV
TREQRLAAADDIIDNSGTAQGIEPLVAALHRRYLELAASATRQD
>Mature_203_residues
AYIVALTGGIGSGKSTVADAFARHGVTVVDADVIARQVVEPGTPALAAIAKRFGNEMLQPDGRLNRAALRQRIFSNPDEK
SWLNQLLHPLIHQKTQCQLAQVTSPYALWVVPLLVENNLQARADRVLVVDVDSETQLARTIARDGISRQQAQNILSAQVT
REQRLAAADDIIDNSGTAQGIEPLVAALHRRYLELAASATRQD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=192, Percent_Identity=36.4583333333333, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI191252795, Length=192, Percent_Identity=36.4583333333333, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI110227607, Length=165, Percent_Identity=28.4848484848485, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI110227605, Length=165, Percent_Identity=28.4848484848485, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI110227603, Length=165, Percent_Identity=28.4848484848485, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI110227601, Length=165, Percent_Identity=28.4848484848485, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI205277394, Length=165, Percent_Identity=28.4848484848485, Blast_Score=78, Evalue=6e-15,
Organism=Escherichia coli, GI1786292, Length=204, Percent_Identity=64.2156862745098, Blast_Score=252, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17554944, Length=179, Percent_Identity=37.4301675977654, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320402, Length=183, Percent_Identity=37.7049180327869, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644728, Length=185, Percent_Identity=37.8378378378378, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24658602, Length=178, Percent_Identity=28.6516853932584, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22175; Mature: 22044

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYIVALTGGIGSGKSTVADAFARHGVTVVDADVIARQVVEPGTPALAAIAKRFGNEMLQ
CEEEEEEECCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
PDGRLNRAALRQRIFSNPDEKSWLNQLLHPLIHQKTQCQLAQVTSPYALWVVPLLVENNL
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCC
QARADRVLVVDVDSETQLARTIARDGISRQQAQNILSAQVTREQRLAAADDIIDNSGTAQ
HHCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GIEPLVAALHRRYLELAASATRQD
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AYIVALTGGIGSGKSTVADAFARHGVTVVDADVIARQVVEPGTPALAAIAKRFGNEMLQ
EEEEEEECCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
PDGRLNRAALRQRIFSNPDEKSWLNQLLHPLIHQKTQCQLAQVTSPYALWVVPLLVENNL
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCC
QARADRVLVVDVDSETQLARTIARDGISRQQAQNILSAQVTREQRLAAADDIIDNSGTAQ
HHCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GIEPLVAALHRRYLELAASATRQD
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA