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The map label for this gene is sgrR [H]

Identifier: 157368983

GI number: 157368983

Start: 820804

End: 822465

Strand: Reverse

Name: sgrR [H]

Synonym: Spro_0738

Alternate gene names: 157368983

Gene position: 822465-820804 (Counterclockwise)

Preceding gene: 157368987

Following gene: 157368982

Centisome position: 15.09

GC content: 58.9

Gene sequence:

>1662_bases
ATGTCCACCTCCAGATTGCAACAGCAGTTCATTCGCCTGTGGCAGCGCTGCCACGGCGAGCCGACCGAAACCACCCTGCA
GGAGCTGGCCGAAGTGCTCAGCTGTTCGCGCCGCCATGTGCGTTCGCTACTGGGTGCCATGCAGCACCAGGGCTGGTTAA
CCTGGCAGGCCGAGTCCGGGCGCGGCAAACGTTCACGGCTCACCTTTCACTACACCGGTCTGGCACTGCAACAGCAGCGG
GCGGAGGAATTGCTGGAGCAAGACCGTATCGATCAACTGGTGCAACTGGTCGGCGATAAAAACGTGGTGCGCCAAATGTT
GCTGTCCCAACTGGGACGCAGCTTTCGTCAGGGGAAACACATCCTGCGGGTGCTCTACTATCGGCAGTTGTACAACCTGC
TGCCCGGCTCGGCGCTGCGGCGTTCGGAAACCCATCTGGCACGGCAGATTTTCAGCGGCCTGACGCGCATAAACGAGGAA
AACGGGGAACTGGAGTCTGATCTTTCGCATCACTGGCAAGCTTTGACCCCGCTGCATTGGCGTTTTTATCTCCGCCCGGC
GATTCATTTTCACCATGGCCGCGAGCTGGAAATGGAGGATGTCATCAGCTCGCTTACCCGTTTGATGCCACAGCCACTGT
TTTCACATCTCGAACGCGTGACCTCACCGACGCCTTATGTGATCGACGTGCATTTGCACAGTCCCGATTACTGGCTACCG
TGGCTGCTGGGCAGCGTGCCCGCGATGATCCTGCCGCGCGAATGGAAAAGCCTGCCGGACTTCTCGCGCCACCCGGTGGG
CACCGGGCCATATAGCGTGGTACGCAACCACCGCAGCCAGATGAAAATCCATGCCTTTGACGATTACTTTGGCTACCGCG
CGCTGATCGATGAGGTGAATATCTGGGTGCTGCCGGAAGTGACCGAAGAACTGGTACATTCCGGCGTCCAGTTGCAGGCG
GACGACACCGGCAAAAACGAACTGGAAAGCCGGCTGGAAGAAGGCTGTTATTTCCTGCTGTTCGATCAGCGTTCGCCACT
GGCGGCCGATCCGGCCATTCGCAGTTGGCTGTGCGAGTTGATCAACCCCATTTCGCTGCTGAGCAATGCCGGCCCGGTCT
ATCAACGCTATTGGTCGCCGGCCTACGGCCTTCTGCCGCGCTGGCATCACAACCGCGCACTGGCACAATTGCCCAAACCG
GACGGGTTGACCGAGCTGACGTTGACTTACTACAGCGAGCACTCGGAGTTCCACGCCATTCAGTTGGCGATCGAACCCCT
GCTGGCGCAGCAGGGTATCAAGCTGAAGATCCAGGCCGTGGATTACGACACCTGGCATAAAGGCGAAGCCATCAGCGATT
TGTGGCTCGGCAGCGCCAACTTCTATCTGCCGCTGGAGTTCTCGCTGTTCGCCACCCTGTATGAACTGCCGCTGATGCAG
CACTGCATGAATGAAGATCTGGCTGAGGATGCCGCGTTGTGGCGCGCCAATAGCCTGCCGCTGGCCGATTTTTGCCAGCG
CCTGGTCAGCAATCATCAGTTACACCCGCTGTTCCACCACTGGTTGCAATTGCACGGCCAGCGCAGCATGCGCGGCGTAC
GGATGAATACCCTGGGCTGGTTTGATTTTAAATCCGCCTGGTTTGCGCCGCCGGAAGCATAA

Upstream 100 bases:

>100_bases
AAACCTTCATCCGTCGCCCTCCCCCTTTCATTGAGGAAAATTATCGGCGTAATATAGGGAAAGATAAATTGATGGGTTGA
TGCCGGAGCGTTCCTCTTTT

Downstream 100 bases:

>100_bases
GCGCCTTTCACCGACGCCCGTTAGTCTTTACAATGACGCCGTCTCAACGGGGTGCAAAATGCGGCGTGCCGATTTTGCTG
AGAACAAACCCGTCGAACCT

Product: transcriptional regulator SgrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MSTSRLQQQFIRLWQRCHGEPTETTLQELAEVLSCSRRHVRSLLGAMQHQGWLTWQAESGRGKRSRLTFHYTGLALQQQR
AEELLEQDRIDQLVQLVGDKNVVRQMLLSQLGRSFRQGKHILRVLYYRQLYNLLPGSALRRSETHLARQIFSGLTRINEE
NGELESDLSHHWQALTPLHWRFYLRPAIHFHHGRELEMEDVISSLTRLMPQPLFSHLERVTSPTPYVIDVHLHSPDYWLP
WLLGSVPAMILPREWKSLPDFSRHPVGTGPYSVVRNHRSQMKIHAFDDYFGYRALIDEVNIWVLPEVTEELVHSGVQLQA
DDTGKNELESRLEEGCYFLLFDQRSPLAADPAIRSWLCELINPISLLSNAGPVYQRYWSPAYGLLPRWHHNRALAQLPKP
DGLTELTLTYYSEHSEFHAIQLAIEPLLAQQGIKLKIQAVDYDTWHKGEAISDLWLGSANFYLPLEFSLFATLYELPLMQ
HCMNEDLAEDAALWRANSLPLADFCQRLVSNHQLHPLFHHWLQLHGQRSMRGVRMNTLGWFDFKSAWFAPPEA

Sequences:

>Translated_553_residues
MSTSRLQQQFIRLWQRCHGEPTETTLQELAEVLSCSRRHVRSLLGAMQHQGWLTWQAESGRGKRSRLTFHYTGLALQQQR
AEELLEQDRIDQLVQLVGDKNVVRQMLLSQLGRSFRQGKHILRVLYYRQLYNLLPGSALRRSETHLARQIFSGLTRINEE
NGELESDLSHHWQALTPLHWRFYLRPAIHFHHGRELEMEDVISSLTRLMPQPLFSHLERVTSPTPYVIDVHLHSPDYWLP
WLLGSVPAMILPREWKSLPDFSRHPVGTGPYSVVRNHRSQMKIHAFDDYFGYRALIDEVNIWVLPEVTEELVHSGVQLQA
DDTGKNELESRLEEGCYFLLFDQRSPLAADPAIRSWLCELINPISLLSNAGPVYQRYWSPAYGLLPRWHHNRALAQLPKP
DGLTELTLTYYSEHSEFHAIQLAIEPLLAQQGIKLKIQAVDYDTWHKGEAISDLWLGSANFYLPLEFSLFATLYELPLMQ
HCMNEDLAEDAALWRANSLPLADFCQRLVSNHQLHPLFHHWLQLHGQRSMRGVRMNTLGWFDFKSAWFAPPEA
>Mature_552_residues
STSRLQQQFIRLWQRCHGEPTETTLQELAEVLSCSRRHVRSLLGAMQHQGWLTWQAESGRGKRSRLTFHYTGLALQQQRA
EELLEQDRIDQLVQLVGDKNVVRQMLLSQLGRSFRQGKHILRVLYYRQLYNLLPGSALRRSETHLARQIFSGLTRINEEN
GELESDLSHHWQALTPLHWRFYLRPAIHFHHGRELEMEDVISSLTRLMPQPLFSHLERVTSPTPYVIDVHLHSPDYWLPW
LLGSVPAMILPREWKSLPDFSRHPVGTGPYSVVRNHRSQMKIHAFDDYFGYRALIDEVNIWVLPEVTEELVHSGVQLQAD
DTGKNELESRLEEGCYFLLFDQRSPLAADPAIRSWLCELINPISLLSNAGPVYQRYWSPAYGLLPRWHHNRALAQLPKPD
GLTELTLTYYSEHSEFHAIQLAIEPLLAQQGIKLKIQAVDYDTWHKGEAISDLWLGSANFYLPLEFSLFATLYELPLMQH
CMNEDLAEDAALWRANSLPLADFCQRLVSNHQLHPLFHHWLQLHGQRSMRGVRMNTLGWFDFKSAWFAPPEA

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=552, Percent_Identity=64.6739130434783, Blast_Score=754, Evalue=0.0,
Organism=Escherichia coli, GI1786650, Length=577, Percent_Identity=29.1161178509532, Blast_Score=196, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64308; Mature: 64177

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSRLQQQFIRLWQRCHGEPTETTLQELAEVLSCSRRHVRSLLGAMQHQGWLTWQAESG
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
RGKRSRLTFHYTGLALQQQRAEELLEQDRIDQLVQLVGDKNVVRQMLLSQLGRSFRQGKH
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRQLYNLLPGSALRRSETHLARQIFSGLTRINEENGELESDLSHHWQALTPLHW
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHH
RFYLRPAIHFHHGRELEMEDVISSLTRLMPQPLFSHLERVTSPTPYVIDVHLHSPDYWLP
HEEEEHHHEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
WLLGSVPAMILPREWKSLPDFSRHPVGTGPYSVVRNHRSQMKIHAFDDYFGYRALIDEVN
HHHHCCCCEEECHHHHCCCCCCCCCCCCCHHHHHHHHHHCEEEEEHHHHHHHHHHHHCCC
IWVLPEVTEELVHSGVQLQADDTGKNELESRLEEGCYFLLFDQRSPLAADPAIRSWLCEL
EEECCHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
INPISLLSNAGPVYQRYWSPAYGLLPRWHHNRALAQLPKPDGLTELTLTYYSEHSEFHAI
HHHHHHHHCCCHHHHHHCCCHHHCCCCCCCCCHHHHCCCCCCCCEEEEEEHHCCCCHHHH
QLAIEPLLAQQGIKLKIQAVDYDTWHKGEAISDLWLGSANFYLPLEFSLFATLYELPLMQ
HHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHH
HCMNEDLAEDAALWRANSLPLADFCQRLVSNHQLHPLFHHWLQLHGQRSMRGVRMNTLGW
HHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCEEECCCCC
FDFKSAWFAPPEA
CCCCCCCCCCCCC
>Mature Secondary Structure 
STSRLQQQFIRLWQRCHGEPTETTLQELAEVLSCSRRHVRSLLGAMQHQGWLTWQAESG
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
RGKRSRLTFHYTGLALQQQRAEELLEQDRIDQLVQLVGDKNVVRQMLLSQLGRSFRQGKH
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRQLYNLLPGSALRRSETHLARQIFSGLTRINEENGELESDLSHHWQALTPLHW
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHH
RFYLRPAIHFHHGRELEMEDVISSLTRLMPQPLFSHLERVTSPTPYVIDVHLHSPDYWLP
HEEEEHHHEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
WLLGSVPAMILPREWKSLPDFSRHPVGTGPYSVVRNHRSQMKIHAFDDYFGYRALIDEVN
HHHHCCCCEEECHHHHCCCCCCCCCCCCCHHHHHHHHHHCEEEEEHHHHHHHHHHHHCCC
IWVLPEVTEELVHSGVQLQADDTGKNELESRLEEGCYFLLFDQRSPLAADPAIRSWLCEL
EEECCHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
INPISLLSNAGPVYQRYWSPAYGLLPRWHHNRALAQLPKPDGLTELTLTYYSEHSEFHAI
HHHHHHHHCCCHHHHHHCCCHHHCCCCCCCCCHHHHCCCCCCCCEEEEEEHHCCCCHHHH
QLAIEPLLAQQGIKLKIQAVDYDTWHKGEAISDLWLGSANFYLPLEFSLFATLYELPLMQ
HHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHH
HCMNEDLAEDAALWRANSLPLADFCQRLVSNHQLHPLFHHWLQLHGQRSMRGVRMNTLGW
HHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCEEECCCCC
FDFKSAWFAPPEA
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA