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The map label for this gene is aaeR [H]

Identifier: 157368947

GI number: 157368947

Start: 774875

End: 775798

Strand: Reverse

Name: aaeR [H]

Synonym: Spro_0702

Alternate gene names: 157368947

Gene position: 775798-774875 (Counterclockwise)

Preceding gene: 157368951

Following gene: 157368941

Centisome position: 14.24

GC content: 52.27

Gene sequence:

>924_bases
ATGAGTAATATTCTAAAACGCATGGCTATTTTTTCTAAAGTTGTCGATTGCGGCGCATTCAGCACGGCAGCCAAAGAATT
AGGCATTACAACCTCCGCCGTCAGCCAACATATCCGCCTGCTGGAAAACGAGTTGGGCATTCAATTACTTCTGCGTTCTA
CCCGTTCACTGAGCCTGACCGAGGCCGGGCTGTGTTTTTATGAGGATTGCGTGTTGATGATCCATGCCGCCGAACGCGGG
CAACAACGTATTGCCGCGCTACGCGGTGAACTGGCCGGGGAACTGCGCGTCGCCACCTCTACGGAGTTTGCCACTCATTA
TCTGGTTCCGGCGCTGCAAAGCTTCCTGGACGAACACCCGCGCATCACGCTGAGGCTGGAAATTCATGATGAAAAGATCG
ACCTGATAAACCAGCGTATTGATCTGGCGATCCGCGGTGGCGTGATGGCTGACTCCAGCTATGTTTCCACCCGTCTGGCG
CGCTTTCGGGAAGTGCTGTGTGCCTCGCCGGCCTACCTTGCCAACCACGGCATGCCAGAAACTCCACAGGCGTTGACGCA
CCATCAATGGGTCACTTTTACCCCGCTGGGAAACCCACAGTTTGTTCGTCTGCTCCACCCTGATGGCGACGAGCATCGGC
TGCGTATGACCGGACGTTTATTTACCAATAACGGCATGGCGATGAAAGAATTGGCGCTGGCCGGTAAAGGGATCATCCGT
AATTTCTTCGTCAATGTTGAAAAGGAATTGAACCGGGGTGAGCTGGTCGAGGTACTGCCAGAGTGGCGCCTACCAGATAT
TAGTTGCTATGCCATTATGCCGCGCAGGGACAGCCAACCATTAAAGGTCCGTCGTTTACTTGAACATATGAAAATCCATT
TACAGCAAAAAGAGCAAAATTCCGTAGGACAATTACGCATTTAA

Upstream 100 bases:

>100_bases
TTACCTCGCGATTTATCTGCTTCAGGCAATATAGAAGAGATAATGCTATATTATTAGCCCTTATAATTAACAATCTTGGT
TAAGTTGAACTTAACAAACT

Downstream 100 bases:

>100_bases
AATAAGAATAATCTGTAACGCCAATTAATTTAGTTATTTAACCTTTCAGCCCGTTGCTGACCAGCACCAGAGTTTATTTA
GATTGCAGCCTAATGATATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSNILKRMAIFSKVVDCGAFSTAAKELGITTSAVSQHIRLLENELGIQLLLRSTRSLSLTEAGLCFYEDCVLMIHAAERG
QQRIAALRGELAGELRVATSTEFATHYLVPALQSFLDEHPRITLRLEIHDEKIDLINQRIDLAIRGGVMADSSYVSTRLA
RFREVLCASPAYLANHGMPETPQALTHHQWVTFTPLGNPQFVRLLHPDGDEHRLRMTGRLFTNNGMAMKELALAGKGIIR
NFFVNVEKELNRGELVEVLPEWRLPDISCYAIMPRRDSQPLKVRRLLEHMKIHLQQKEQNSVGQLRI

Sequences:

>Translated_307_residues
MSNILKRMAIFSKVVDCGAFSTAAKELGITTSAVSQHIRLLENELGIQLLLRSTRSLSLTEAGLCFYEDCVLMIHAAERG
QQRIAALRGELAGELRVATSTEFATHYLVPALQSFLDEHPRITLRLEIHDEKIDLINQRIDLAIRGGVMADSSYVSTRLA
RFREVLCASPAYLANHGMPETPQALTHHQWVTFTPLGNPQFVRLLHPDGDEHRLRMTGRLFTNNGMAMKELALAGKGIIR
NFFVNVEKELNRGELVEVLPEWRLPDISCYAIMPRRDSQPLKVRRLLEHMKIHLQQKEQNSVGQLRI
>Mature_306_residues
SNILKRMAIFSKVVDCGAFSTAAKELGITTSAVSQHIRLLENELGIQLLLRSTRSLSLTEAGLCFYEDCVLMIHAAERGQ
QRIAALRGELAGELRVATSTEFATHYLVPALQSFLDEHPRITLRLEIHDEKIDLINQRIDLAIRGGVMADSSYVSTRLAR
FREVLCASPAYLANHGMPETPQALTHHQWVTFTPLGNPQFVRLLHPDGDEHRLRMTGRLFTNNGMAMKELALAGKGIIRN
FFVNVEKELNRGELVEVLPEWRLPDISCYAIMPRRDSQPLKVRRLLEHMKIHLQQKEQNSVGQLRI

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=36.013986013986, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1786401, Length=303, Percent_Identity=31.6831683168317, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI145693193, Length=277, Percent_Identity=32.4909747292419, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=28.4246575342466, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=29.2929292929293, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787589, Length=263, Percent_Identity=29.6577946768061, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=28.0821917808219, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789173, Length=264, Percent_Identity=28.7878787878788, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786448, Length=255, Percent_Identity=30.9803921568627, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788706, Length=184, Percent_Identity=33.1521739130435, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI157672245, Length=137, Percent_Identity=32.8467153284672, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=144, Percent_Identity=29.8611111111111, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=282, Percent_Identity=21.9858156028369, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786508, Length=185, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790011, Length=297, Percent_Identity=24.9158249158249, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34738; Mature: 34607

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNILKRMAIFSKVVDCGAFSTAAKELGITTSAVSQHIRLLENELGIQLLLRSTRSLSLT
CHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EAGLCFYEDCVLMIHAAERGQQRIAALRGELAGELRVATSTEFATHYLVPALQSFLDEHP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCC
RITLRLEIHDEKIDLINQRIDLAIRGGVMADSSYVSTRLARFREVLCASPAYLANHGMPE
CEEEEEEECCHHHHHHHHHHCEEEECCEEECHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
TPQALTHHQWVTFTPLGNPQFVRLLHPDGDEHRLRMTGRLFTNNGMAMKELALAGKGIIR
CCHHHHCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHH
NFFVNVEKELNRGELVEVLPEWRLPDISCYAIMPRRDSQPLKVRRLLEHMKIHLQQKEQN
HHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
SVGQLRI
CCCCCCC
>Mature Secondary Structure 
SNILKRMAIFSKVVDCGAFSTAAKELGITTSAVSQHIRLLENELGIQLLLRSTRSLSLT
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EAGLCFYEDCVLMIHAAERGQQRIAALRGELAGELRVATSTEFATHYLVPALQSFLDEHP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCC
RITLRLEIHDEKIDLINQRIDLAIRGGVMADSSYVSTRLARFREVLCASPAYLANHGMPE
CEEEEEEECCHHHHHHHHHHCEEEECCEEECHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
TPQALTHHQWVTFTPLGNPQFVRLLHPDGDEHRLRMTGRLFTNNGMAMKELALAGKGIIR
CCHHHHCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHH
NFFVNVEKELNRGELVEVLPEWRLPDISCYAIMPRRDSQPLKVRRLLEHMKIHLQQKEQN
HHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
SVGQLRI
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]